A zinc finger HIT domain-containing protein, ZNHIT-1, interacts with orphan nuclear hormone receptor Rev-erbβ and removes Rev-erbβ-induced inhibition of apoCIII transcription

FEBS Journal

Volumn 274, Issue 20, 2007, Pages 5370-5381

  Wang, Jiadong ^a   Li, Yang ^a   Zhang, Min ^a   Liu, Zhongle ^a   Wu, Cong ^a   Yuan, Hanying ^a   Li, Yu Yang ^a   Zhao, Xin ^b   Lu, Hong ^a  

^a FUDAN UNIVERSITY   (China)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

ApoCIII; Rev erb ; Transcriptional regulation; Zinc finger HIT domain containing protein 1; ZNHIT 1

Indexed keywords

AMINO ACID; APOLIPOPROTEIN C3; DNA; GLUTATHIONE TRANSFERASE; HEPARIN PLATELET FACTOR 4 ANTIBODY; PROTEIN REV ERB BETA; RECEPTOR PROTEIN; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DNA BINDING; GENE MAPPING; GENETIC TRANSCRIPTION; HUMAN; HUMAN TISSUE; LIPID METABOLISM; MUTATION; NUCLEAR LOCALIZATION SIGNAL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; TISSUE DISTRIBUTION; TWO HYBRID SYSTEM;

AMINO ACID SEQUENCE; APOLIPOPROTEIN C-III; CHROMATIN IMMUNOPRECIPITATION; DNA-BINDING PROTEINS; GENE LIBRARY; GLUTATHIONE TRANSFERASE; HUMANS; IMMUNOPRECIPITATION; LUCIFERASES; MOLECULAR SEQUENCE DATA; NUCLEAR LOCALIZATION SIGNALS; PHOSPHOPROTEINS; PROMOTER REGIONS (GENETICS); RECEPTORS, CYTOPLASMIC AND NUCLEAR; REPRESSOR PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SUBCELLULAR FRACTIONS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TWO-HYBRID SYSTEM TECHNIQUES; ZINC FINGERS;

EUKARYOTA; MUS; RATTUS;

EID: 34848903026     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2007.06062.x     Document Type: Article

References (40)

1. Robinson-Rechavi M, Escriva Garcia H Laudet V (2003) The nuclear receptor superfamily. J Cell 116, 585 586.
2. Rosen J, Marschke K Rungta D (2003) Nuclear hormone receptor assays for drug discovery. Curr Opin Drug Discov Devel 6, 224 230.
3. Smith CL O'Malley BW (2004) Coregulator function: a key to understanding tissue specificity of selective receptor modulators. Endocr Rev 25, 45 71.
4. Lazar MA, Hodin RA, Darling DS Chin WW (1989) A novel member of the thyroid/steroid hormone receptor family is encoded by the opposite strand of the rat c-erbA alpha transcriptional unit. Mol Cell Biol 9, 1128 1136.
5. Burke L, Downes M, Carozzi A, Gigue're V Muscat GE (1996) Transcriptional repression by the orphan steroid receptor Rev-erbβ/Rev-erb beta is dependent on the signature motif and helix 5 in the E region: functional evidence for a biological role of Rev-erbβ in myogenesis. Nucleic Acids Res 24, 3481 3489.
6. Downes M, Burke LJ, Bailey PJ Muscat GE (1996) Two receptor interaction domains in the corepressor, N-CoR/RIP13, are required for an efficient interaction with Rev-erbA alpha and Rev-erbβ: physical association is dependent on the E region of the orphan receptors. Nucleic Acids Res 24, 4379 4386.
7. Adelmant G, Be'gue A, Stehelin D Laudet V (1996) A functional Rev-erb responsive element located in the human Rev-erb promoter mediates a repressing activity. Proc Natl Acad Sci USA 93, 3553 3558.
8. Dussault I Giguere V (1997) Differential regulation of the N-myc proto-oncogene by ROR alpha and Rev-erbβ, two orphan members of the superfamily of nuclear hormone receptors. Mol Cell Biol 17, 1860 1867.
9. Yin L Lazar MA (2005) The orphan nuclear receptor Rev-erbalpha recruits the N-CoR/histone deacetylase 3 corepressor to regulate the circadian Bmal1 gene. Mol Endocrinol 19, 1452 1459.
10. Kassam A, Capone JP Rachubinski RA (1999) Orphan nuclear hormone receptor RevErb modulates expression from the promoter of the hydratase-dehydrogenase gene by inhibiting peroxisome proliferator-activated receptor α-dependent transactivation. J Biol Chem 274, 22 895 22 900.
11. Bois-Joyeux B, Chauvet C, Nacer-Che'rif H, Bergeret W, Mazure N, Gigue're V, Laudet V Danan JL (2000) Modulation of the far upstream enhancer of the rat a-fetoprotein gene by members of the RORα, Rev-erbα and Rev-erbβ groups of monomeric orphan nuclear receptors. DNA Cell Biol 19, 589 599.
12. Vu-Dac N, Chopin-Delannoy S, Gervois P, Bonnelye E, Martin G, Fruchart JC, Laudet V Staels B (1998) The nuclear receptors peroxisome proliferator-activated receptor alpha and Rev-erbalpha mediate the species-specific regulation of apolipoprotein AI expression by fibrates. J Biol Chem 273, 25 713 25 720.
13. Balsalobre A, Damiola F Schibler U (1998) A serum shock induces circadian gene expression in mammalian tissue culture cells. Cell 93, 929 937.
14. Delaunay F, Thisse C, Marchand O, Laudet V Thisse B (2000) An inherited functional circadian clock in zebrafish embryos. Science 289, 297 300.
15. Triqueneaux G, Thenot S, Kakizawa T, Antoch MP, Safi R, Takahashi JS, Delaunay F Laudet V (2004) The orphan receptor Rev-erbalpha gene is a target of the circadian clock pacemaker. J Mol Endocrinol 33, 585 608.
16. Preitner N, Damiola F, Lopez-Molina L, Zakany J, Duboule D, Albrecht U Schibler U (2002) The orphan nuclear receptor REV-ERBalpha controls circadian transcription within the positive limb of the mammalian circadian oscillator. Cell 110, 251 260.
17. Coste H Rodriguez JC (2002) Orphan nuclear hormone receptor Rev-erbalpha regulates the human apolipoprotein CIII promoter. J Biol Chem 277, 27 120 27 129.
18. Shachter NS (2001) Apolipoproteins C-I and C-III as important modulators of lipoprotein metabolism. Curr Opin Lipidol 12, 297 304.
19. Assmann G, Schulte H von Eckardstein A (1996) Hypertriglyceridemia and elevated lipoprotein (a) are risk factors for major coronary events in middle-aged men. Am J Cardiol 77, 1179 1184.
20. Krauss RM (1998) Atherogenicity of triglyceride-rich lipoproteins. Am J Cardiol 81, 13B 17B.
21. Hasty AH, Shimano H, Osuga J Yamada N (2001) Severe hypercholesterolemia, hypertriglyceridemia, and atherosclerosis in mice lacking both leptin and the low density lipoprotein receptor. J Biol Chem 276, 37 402 37 408.
22. Tybjaerg-Hansen A, Nordestgaard BG, Gerdes LU, Faergeman O Humphries SE (1993) Genetic markers in the apo AI-CIII-AIV gene cluster for combined hyperlipidemia, hypertriglyceridemia, and predisposition to atherosclerosis. Atherosclerosis 100, 157 169.
23. Galibert F, Alexandraki D, Baur A, Boles E, Chalwatzis N, Chuat J-C, Coster F, Cziepluch C Karpfinger-Hartl L (1996) Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X. EMBO J 15, 2031 2049.
24. Cai Y, Jin J, Florens L, Swanson SK, Kusch T, Li B, Workman JL, Washburn MP, Conaway RC Conaway JW (2005) The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes. J Biol Chem 280, 13 665 13 670.
25. He F, Umehara T, Tsuda K, Inoue M, Kigawa T, Matsuda T, Yabuki T, Aoki M, Seki E, Terada T et al. (2007) Solution structure of the zinc finger HIT domain in protein FON. Protein Sci 16, 1577 1587.
26. Le Douarin B, Lade Nielsen A, Garnier J-M, Ichinose H, Jeanmougin F, Losson R Chambon P (1996) A possible involvement of TIF1a and TIF1b in the epigenetic control of transcription by nuclear receptors. EMBO J 15, 6701 6715.
27. Heery DM, Kalkhoven E, Hoare S Parker MG (1997) A signature motif in transcriptional co-activators mediates binding to nuclear receptors. Nature 387, 733 736.
28. Heery DM, Hoare S, Hussain S, Parker MG Sheppard H (2001) Core LXXLL motif sequences in CREB-binding protein, SRC1, and RIP140 define affinity and selectivity for steroid and retinoid receptors. J Biol Chem 276, 6695 6702.
29. Burke LJ, Downes M, Laudet V Muscat GE (1998) Identification and characterization of a novel corepressor interaction region in RVR and Rev-erbA alpha. Mol Endocrinol 12, 248 262.
30. Raspe E, Duez H, Mansen A, Fontaine C, Fievet C, Fruchart JC, Vennstrom B Staels B (2002) Identification of Rev-erbalpha as a physiological repressor of apoC-III gene transcription. J Lipid Res 43, 2172 2181.
31. Chomez P, Neveu I, Mansen A, Kiesler E, Larsson L, Vennstrom B Arenas E (2000) Increased cell death and delayed development in the cerebellum of mice lacking the Rev-erbA (α) orphan receptor. Development 127, 1489 1498.
32. Huang N, vom Baur E, Garnier JM, Lerouge T, Vonesch JL, Lutz Y, Chambon P Losson R (1998) Two distinct nuclear receptor interaction domains in NSD1, a novel SET protein that exhibits characteristics of both corepressors and coactivators. EMBO J 17, 3398 3412.
33. Storch KF, Lipan O, Leykin I, Viswanathan N, Davis FC, Wong WH Weitz CJ (2002) Extensive and divergent circadian gene expression in liver and heart. Nature 417, 78 83.
34. Reinking J, Lam MM, Pardee K, Sampson HM, Liu S, Yang P, Williams S, White W, Lajoie G, Edwards A et al. (2005) The Drosophila nuclear receptor e75 contains heme and is gas responsive. Cell 122, 195 207.
35. Krogan NJ, Baetz K, Keogh M-C, Datta N, Sawa C, Hieter TP Greenblatt JF (2004) Regulation of chromosome stability by the histone H2A variant Htz1, the Swr1 chromatin remodeling complex, and the histone acetyltransferase NuA4. Proc Natl Acad Sci USA 101, 13 513 13 518.
36. Li B, Pattenden SG, Lee D, Gutiérrez J, Chen J, Seidel C, Gerton J Workman JL (2005) Preferential occupancy of histone variant H2AZ at inactive promoters influences local histone modifications and chromatin remodeling. Proc Natl Acad Sci USA 102, 18 385 18 390.
37. Ruhl DD, Jin J, Cai Y, Swanson S, Florens L, Washburn MP, Conaway RC, Conaway JW Chrivia JC (2006) Purification of a human SRCAP complex that remodels chromatin by incorporating the histone variant H2A.Z into nucleosomes. Biochemistry 45, 5671 5677.
38. Shen L, Hu J, Lu H, Wu M, Qin W, Wan DF, Li YY Gu JR (2003) The apoptosis-associated protein BNIPL interacts with two cell proliferation-related proteins, MIF and GFER. FEBS Lett 540, 86 90.
39. Reid G, Metivier R, Lin CY, Denger S, Ibberson D, Ivacevic T, Brand H, Benes V, Liu ET Gannon F (2005) Multiple mechanisms induce transcriptional silencing of a subset of genes, including oestrogen receptor alpha, in response to deacetylase inhibition by valproic acid and trichostatin A. Oncogene 24, 4894 4907.
40. Hearnes JM, Mays DJ, Schavolt KL, Tang L, Jiang X Pietenpol JA (2005) Chromatin immunoprecipitation-based screen to identify functional genomic binding sites for sequence-specific transactivators. Mol Cell Biol 25, 10 148 10 158.