Confronting the challenges of discovery of novel antibacterial agents

Bioorganic and Medicinal Chemistry Letters

Volumn 24, Issue 16, 2014, Pages 3683-3689

  Singh, Sheo B ^a  

^a SBS Pharma Consulting LLC   (United States)

Author keywords

Antibacterial; Antimicrobial; Discovery strategy; Phenotypic screening; Topoisomerase II

Indexed keywords

AM 8191; ANTIBIOTIC AGENT; ANTIINFECTIVE AGENT; AVIBACTAM; AZD 0914; BAL 30072; BARBITURIC ACID DERIVATIVE; BETA LACTAMASE INHIBITOR; CADAZOLID; CEFTAZIDIME; CHIR 090; CIPROFLOXACIN; COUMARIN DERIVATIVE; ERAVACYCLINE; GSK 2140944; GSK 299423; GYRASE INHIBITOR; IMIPENEM; L 161240; MK 7655; NOVOBIOCIN; PNU 286607; PYRIDOXAL 5 PHOSPHATE; PYRROLE DERIVATIVE; QPT 1; QUINOLONE DERIVATIVE; RPX 7009; TETRACYCLINE DERIVATIVE; UNCLASSIFIED DRUG; VIQUIDACIN; VRT 752586;

ARTICLE; DRUG MECHANISM; DRUG SCREENING; DRUG STRUCTURE; GROWTH INHIBITION; NONHUMAN; BACTERIA; CHEMICAL STRUCTURE; CHEMISTRY; DRUG DEVELOPMENT; DRUG EFFECTS; HUMAN; MICROBIAL SENSITIVITY TEST; SYNTHESIS; ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; HISTORY;

BACTERIA (MICROORGANISMS);

ANTI-BACTERIAL AGENTS; BACTERIA; DRUG DISCOVERY; HUMANS; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE;

EID: 84905919391     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2014.06.053     Document Type: Review

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