Opposite orientations of a transcription factor heterodimer bind DNA cooperatively with interaction partners but have different effects on interferon-β gene transcription

Journal of Biological Chemistry

Volumn 287, Issue 38, 2012, Pages 31833-31844

  Burns, Veronica ^a   Kerppola, Tom Klaus ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID RESIDUES; COEXPRESSED; COMPLEX CONFIGURATION; COMPLEX FORMATIONS; COOPERATIVITY; CULTURED CELL; DIFFERENT EFFECTS; DNA BINDING; ENDOGENOUS GENES; GENE TRANSCRIPTIONS; HETERODIMERS; IN-VITRO; REGULATORY ELEMENTS; TRANSCRIPTIONAL ACTIVITY;

AMINO ACIDS; ANTIBIOTICS; GENES; GLYCOPROTEINS; NUCLEIC ACIDS; TRANSCRIPTION FACTORS;

TRANSCRIPTION;

ACTIVATING TRANSCRIPTION FACTOR 2; BETA INTERFERON; DNA; HETERODIMER; HIGH MOBILITY GROUP I PROTEIN; HIGH MOBILITY GROUP PROTEIN; INTERFERON REGULATORY FACTOR 3; PROTEIN C JUN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DNA BINDING; ENHANCER REGION; GENE; GENETIC TRANSCRIPTION; IN VITRO STUDY; INTERFERON BETA GENE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION;

ACTIVATING TRANSCRIPTION FACTOR 2; DIMERIZATION; DNA; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENE EXPRESSION REGULATION; HMGA1A PROTEIN; HUMANS; INTERFERON REGULATORY FACTOR-3; INTERFERON-BETA; JNK MITOGEN-ACTIVATED PROTEIN KINASES; NUCLEOPROTEINS; OLIGONUCLEOTIDES; PROTEIN BINDING; PROTEIN CONFORMATION; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 84866398522     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.374462     Document Type: Article

References (24)

1. Glover, J. N., and Harrison, S. C. (1995) Crystal structure of the heterodimeric bZIP transcription factor c-Fos-c-Jun bound to DNA. Nature 373, 257-261
2. Leonard, D. A., and Kerppola, T. K. (1998) DNA bending determines Fos-Jun heterodimer orientation. Nat. Struct. Biol. 5, 877-881 (Pubitemid 28467409)
3. Chen, L., Oakley, M. G., Glover, J. N., Jain, J., Dervan, P. B., Hogan, P. G., Rao, A., and Verdine, G. L. (1995) Only one of the two DNA-bound orientations of AP-1 found in solution cooperates with NFATp. Curr. Biol. 5, 882-889
4. Chen, L., Glover, J. N., Hogan, P. G., Rao, A., and Harrison, S. C. (1998) Structure of the DNA-binding domains from NFAT, Fos and Jun bound specifically to DNA. Nature 392, 42-48 (Pubitemid 28150581)
5. Diebold, R. J., Rajaram, N., Leonard, D. A., and Kerppola, T. K. (1998) Molecular basis of cooperative DNA bending and oriented heterodimer binding in the NFAT1-Fos-Jun-ARRE2 complex. Proc. Natl. Acad. Sci. U.S.A. 95, 7915-7920
6. Ramirez-Carrozzi, V. R., and Kerppola, T. K. (2001) Control of the orientation of Fos-Jun binding and the transcriptional cooperativity of Fos-Jun-NFAT1 complexes. J. Biol. Chem. 276, 21797-21808
7. Ramirez-Carrozzi, V. R., and Kerppola, T. K. (2001) Dynamics of Fos-Jun-NFAT1 complexes. Proc. Natl. Acad. Sci. U.S.A. 98, 4893-4898 (Pubitemid 32397053)
8. Ramirez-Carrozzi, V., and Kerppola, T. (2003) Asymmetric recognition of nonconsensus AP-1 sites by Fos-Jun and Jun-Jun influences transcriptional cooperativity with NFAT1. Mol. Cell. Biol. 23, 1737-1749
9. Falvo, J. V., Parekh, B. S., Lin, C. H., Fraenkel, E., and Maniatis, T. (2000) Assembly of a functional β interferon enhanceosome is dependent on ATF-2-c-Jun heterodimer orientation. Mol. Cell. Biol. 20, 4814-4825 (Pubitemid 30396128)
10. Panne, D., Maniatis, T., and Harrison, S. C. (2004) Crystal structure of ATF-2/c-Jun and IRF-3 bound to the interferon-β enhancer. EMBO J. 23, 4384-4393 (Pubitemid 39601963)
11. Dragan, A. I., Carrillo, R., Gerasimova, T. I., and Privalov, P. L. (2008) Assembling the human IFN-β enhanceosome in solution. J. Mol. Biol. 384, 335-348
12. Agalioti, T., Lomvardas, S., Parekh, B., Yie, J., Maniatis, T., and Thanos, D. (2000) Ordered recruitment of chromatin modifying and general transcription factors to the IFN-β promoter. Cell 103, 667-678
13. Kim, T. K., Kim, T. H., and Maniatis, T. (1998) Efficient recruitment of TFIIB and CBP-RNA polymerase II holoenzyme by an interferon-β enhanceosome in vitro. Proc. Natl. Acad. Sci. U.S.A. 95, 12191-12196 (Pubitemid 28483741)
14. Kim, T. K., and Maniatis, T. (1997) The mechanism of transcriptional synergy of an in vitro assembled interferon-β enhanceosome. Mol. Cell 1, 119-129 (Pubitemid 127376399)
15. Munshi, N., Agalioti, T., Lomvardas, S., Merika, M., Chen, G., and Thanos, D. (2001) Coordination of a transcriptional switch by HMGI(Y) acetylation. Science 293, 1133-1136 (Pubitemid 32758093)
16. Kerppola, T. K., and Curran, T. (1993) Selective DNA bending by a variety of bZIP proteins. Mol. Cell. Biol. 13, 5479-5489 (Pubitemid 23260651)
17. Ramirez-Carrozzi, V., and Kerppola, T. (2001) Gel-based fluorescence resonance energy transfer (gelFRET) analysis of nucleoprotein complex architecture. Methods 25, 31-43 (Pubitemid 32905286)
18. Leonard, D. A., Rajaram, N., and Kerppola, T. K. (1997) Structural basis of DNA bending and oriented heterodimer binding by the basic leucine zipper domains of Fos and Jun. Proc. Natl. Acad. Sci. U.S.A. 94, 4913-4918 (Pubitemid 27214710)
19. Schräder, M., Müller, K. M., Nayeri, S., Kahlen, J. P., and Carlberg, C. (1994) Vitamin D3-thyroid hormone receptor heterodimer polarity directs ligand sensitivity of transactivation. Nature 370, 382-386
20. Scully, K. M., Jacobson, E. M., Jepsen, K., Lunyak, V., Viadiu, H., Carrière, C., Rose, D. W., Hooshmand, F., Aggarwal, A. K., and Rosenfeld, M. G. (2000) Allosteric effects of Pit-1 DNA sites on long-term repression in cell type specification. Science 290, 1127-1131
21. Tomilin, A., Reményi, A., Lins, K., Bak, H., Leidel, S., Vriend, G., Wilmanns, M., and Schöler, H. R. (2000) Synergism with the coactivator OBF-1 (OCA-B, BOB-1) is mediated by a specific POU dimer configuration. Cell 103, 853-864
22. Core, L. J., Waterfall, J. J., and Lis, J. T. (2008) Nascent RNA sequencing reveals widespread pausing and divergent initiation at human promoters. Science 322, 1845-1848
23. Seila, A. C., Calabrese, J. M., Levine, S. S., Yeo, G. W., Rahl, P. B., Flynn, R. A., Young, R. A., and Sharp, P. A. (2008) Divergent transcription from active promoters. Science 322, 1849-1851
24. Cox, J. M., Hayward, M. M., Sanchez, J. F., Gegnas, L. D., van der Zee, S., Dennis, J. H., Sigler, P. B., and Schepartz, A. (1997) Bidirectional binding of the TATA box binding protein to the TATA box. Proc. Natl. Acad. Sci. U.S.A. 94, 13475-13480 (Pubitemid 28009607)