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Volumn 289, Issue 31, 2014, Pages 21205-21216

A role for the p75 neurotrophin receptor in axonal degeneration and apoptosis induced by oxidative stress

Author keywords

[No Author keywords available]

Indexed keywords

CELL DEATH; ENZYME INHIBITION; LIGANDS; MAMMALS; OXIDATIVE STRESS; PROTEOLYSIS;

EID: 84905364682     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.563403     Document Type: Article
Times cited : (52)

References (87)
  • 1
    • 84905386927 scopus 로고    scopus 로고
    • The biological functions and signaling mechanisms of the p75 neurotrophin receptor
    • Kraemer, B. R., Yoon, S. O., and Carter, B. D. (2014) The biological functions and signaling mechanisms of the p75 neurotrophin receptor. Handb. Exp. Pharmacol. 220, 121-164
    • (2014) Handb. Exp. Pharmacol. , vol.220 , pp. 121-164
    • Kraemer, B.R.1    Yoon, S.O.2    Carter, B.D.3
  • 3
    • 0038045714 scopus 로고    scopus 로고
    • Proteolytic processing of the p75 neurotrophin receptor and two homologs generates C-terminal fragments with signaling capability
    • Kanning, K. C., Hudson, M., Amieux, P. S., Wiley, J. C., Bothwell, M., and Schecterson, L. C. (2003) Proteolytic processing of the p75 neurotrophin receptor and two homologs generates C-terminal fragments with signaling capability. J. Neurosci. 23, 5425-5436 (Pubitemid 36807816)
    • (2003) Journal of Neuroscience , vol.23 , Issue.13 , pp. 5425-5436
    • Kanning, K.C.1    Hudson, M.2    Amieux, P.S.3    Wiley, J.C.4    Bothwell, M.5    Schecterson, L.C.6
  • 4
    • 1042278167 scopus 로고    scopus 로고
    • Evidence for a critical role of the tumor necrosis factor α convertase (TACE) in ectodomain shedding of the p75 neurotrophin receptor (p75NTR)
    • Weskamp, G., Schlöndorff, J., Lum, L., Becherer, J. D., Kim, T. W., Saftig, P., Hartmann, D., Murphy, G., and Blobel, C. P. (2004) Evidence for a critical role of the tumor necrosis factor α convertase (TACE) in ectodomain shedding of the p75 neurotrophin receptor (p75NTR). J. Biol. Chem. 279, 4241-4249
    • (2004) J. Biol. Chem. , vol.279 , pp. 4241-4249
    • Weskamp, G.1    Schlöndorff, J.2    Lum, L.3    Becherer, J.D.4    Kim, T.W.5    Saftig, P.6    Hartmann, D.7    Murphy, G.8    Blobel, C.P.9
  • 5
    • 33646052860 scopus 로고    scopus 로고
    • Ligand-dependent cleavage of the P75 neurotrophin receptor is necessary for NRIF nuclear translocation and apoptosis in sympathetic neurons
    • Kenchappa, R. S., Zampieri, N., Chao, M. V., Barker, P. A., Teng, H. K., Hempstead, B. L., and Carter, B. D. (2006) Ligand-dependent cleavage of the P75 neurotrophin receptor is necessary for NRIF nuclear translocation and apoptosis in sympathetic neurons. Neuron 50, 219-232
    • (2006) Neuron , vol.50 , pp. 219-232
    • Kenchappa, R.S.1    Zampieri, N.2    Chao, M.V.3    Barker, P.A.4    Teng, H.K.5    Hempstead, B.L.6    Carter, B.D.7
  • 6
    • 77953744202 scopus 로고    scopus 로고
    • p75 neurotrophin receptor-mediated apoptosis in sympathetic neurons involves a biphasic activation of JNK and up-regulation of tumor necrosis factor-α-converting enzyme/ADAM17
    • Kenchappa, R. S., Tep, C., Korade, Z., Urra, S., Bronfman, F. C., Yoon, S. O., and Carter, B. D. (2010) p75 neurotrophin receptor-mediated apoptosis in sympathetic neurons involves a biphasic activation of JNK and up-regulation of tumor necrosis factor-α-converting enzyme/ADAM17. J. Biol. Chem. 285, 20358-20368
    • (2010) J. Biol. Chem. , vol.285 , pp. 20358-20368
    • Kenchappa, R.S.1    Tep, C.2    Korade, Z.3    Urra, S.4    Bronfman, F.C.5    Yoon, S.O.6    Carter, B.D.7
  • 7
    • 20444365447 scopus 로고    scopus 로고
    • MAG induces regulated intramembrane proteolysis of the p75 neurotrophin receptor to inhibit neurite outgrowth
    • DOI 10.1016/j.neuron.2005.05.029, PII S0896627305004769
    • Domeniconi, M., Zampieri, N., Spencer, T., Hilaire, M., Mellado, W., Chao, M. V., and Filbin, M. T. (2005) MAG induces regulated intramembrane proteolysis of the p75 neurotrophin receptor to inhibit neurite outgrowth. Neuron 46, 849-855 (Pubitemid 40805346)
    • (2005) Neuron , vol.46 , Issue.6 , pp. 849-855
    • Domeniconi, M.1    Zampieri, N.2    Spencer, T.3    Hilaire, M.4    Mellado, W.5    Chao, M.V.6    Filbin, M.T.7
  • 8
    • 79957926130 scopus 로고    scopus 로고
    • Trk-dependent ADAM17 activation facilitates neurotrophin survival signaling
    • Kommaddi, R. P., Thomas, R., Ceni, C., Daigneault, K., and Barker, P. A. (2011) Trk-dependent ADAM17 activation facilitates neurotrophin survival signaling. FASEB J. 25, 2061-2070
    • (2011) FASEB J. , vol.25 , pp. 2061-2070
    • Kommaddi, R.P.1    Thomas, R.2    Ceni, C.3    Daigneault, K.4    Barker, P.A.5
  • 9
    • 0029787071 scopus 로고    scopus 로고
    • Induction of cell death by endogenous nerve growth factor through its p75 receptor
    • Frade, J. M., Rodríguez-Tébar, A., and Barde, Y. A. (1996) Induction of cell death by endogenous nerve growth factor through its p75 receptor. Nature 383, 166-168
    • (1996) Nature , vol.383 , pp. 166-168
    • Frade, J.M.1    Rodríguez-Tébar, A.2    Barde, Y.A.3
  • 10
    • 0036550661 scopus 로고    scopus 로고
    • NTR Leads to Long-Lasting Increases in the Number of Basal Forebrain Cholinergic Neurons
    • Naumann, T., Casademunt, E., Hollerbach, E., Hofmann, J., Dechant, G., Frotscher, M., and Barde, Y. A. (2002) Complete deletion of the neurotrophin receptor p75NTR leads to long-lasting increases in the number of basal forebrain cholinergic neurons. J. Neurosci. 22, 2409-2418 (Pubitemid 37465788)
    • (2002) Journal of Neuroscience , vol.22 , Issue.7 , pp. 2409-2418
    • Naumann, T.1    Casademunt, E.2    Hollerbach, E.3    Hofmann, J.4    Dechant, G.5    Frotscher, M.6    Barde, Y.-A.7
  • 11
    • 0032559622 scopus 로고    scopus 로고
    • The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron death
    • DOI 10.1083/jcb.140.4.911
    • Bamji, S. X., Majdan, M., Pozniak, C. D., Belliveau, D. J., Aloyz, R., Kohn, J., Causing, C. G., and Miller, F. D. (1998) The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron death. J. Cell Biol. 140, 911-923 (Pubitemid 28141228)
    • (1998) Journal of Cell Biology , vol.140 , Issue.4 , pp. 911-923
    • Bamji, S.X.1    Majdan, M.2    Pozniak, C.D.3    Belliveau, D.J.4    Aloyz, R.5    Kohn, J.6    Causing, C.G.7    Miller, F.D.8
  • 12
    • 0032968762 scopus 로고    scopus 로고
    • Genetic evidence for cell death mediated by nerve growth factor and the neurotrophin receptor p75 in the developing mouse retina and spinal cord
    • Frade, J. M., and Barde, Y. A. (1999) Genetic evidence for cell death mediated by nerve growth factor and the neurotrophin receptor p75 in the developing mouse retina and spinal cord. Development 126, 683-690 (Pubitemid 29106175)
    • (1999) Development , vol.126 , Issue.4 , pp. 683-690
    • Frade, J.M.1    Barde, Y.-A.2
  • 13
    • 77951667668 scopus 로고    scopus 로고
    • p75NTR-dependent, myelin-mediated axonal degeneration regulates neural connectivity in the adult brain
    • Park, K. J., Grosso, C. A., Aubert, I., Kaplan, D. R., and Miller, F. D. (2010) p75NTR-dependent, myelin-mediated axonal degeneration regulates neural connectivity in the adult brain. Nat. Neurosci. 13, 559-566
    • (2010) Nat. Neurosci. , vol.13 , pp. 559-566
    • Park, K.J.1    Grosso, C.A.2    Aubert, I.3    Kaplan, D.R.4    Miller, F.D.5
  • 14
    • 44349087637 scopus 로고    scopus 로고
    • Developmental axon pruning mediated by BDNF-p75NTR-dependent axon degeneration
    • DOI 10.1038/nn.2114, PII NN2114
    • Singh, K. K., Park, K. J., Hong, E. J., Kramer, B. M., Greenberg, M. E., Kaplan, D. R., and Miller, F. D. (2008) Developmental axon pruning mediated by BDNF-p75NTR-dependent axon degeneration. Nat. Neurosci. 11, 649-658 (Pubitemid 351748111)
    • (2008) Nature Neuroscience , vol.11 , Issue.6 , pp. 649-658
    • Singh, K.K.1    Park, K.J.2    Hong, E.J.3    Kramer, B.M.4    Greenberg, M.E.5    Kaplan, D.R.6    Miller, F.D.7
  • 15
    • 0033987763 scopus 로고    scopus 로고
    • Overexpression of neurotrophin receptor p75 contributes to the excitotoxin-induced cholinergic neuronal death in rat basal forebrain
    • DOI 10.1016/S0006-8993(99)02054-5, PII S0006899399020545
    • Oh, J. D., Chartisathian, K., Chase, T. N., and Butcher, L. L. (2000) Overexpression of neurotrophin receptor p75 contributes to the excitotoxin-induced cholinergic neuronal death in rat basal forebrain. Brain Res. 853, 174-185 (Pubitemid 30035217)
    • (2000) Brain Research , vol.853 , Issue.2 , pp. 174-185
    • Oh, J.D.1    Chartisathian, K.2    Chase, T.N.3    Butcher, L.L.4
  • 16
    • 55749104402 scopus 로고    scopus 로고
    • Induction of proneurotrophins and activation of p75NTR-mediated apoptosis via neurotrophin receptor-interacting factor in hippocampal neurons after seizures
    • Volosin, M., Trotter, C., Cragnolini, A., Kenchappa, R. S., Light, M., Hempstead, B. L., Carter, B. D., and Friedman, W. J. (2008) Induction of proneurotrophins and activation of p75NTR-mediated apoptosis via neurotrophin receptor-interacting factor in hippocampal neurons after seizures. J. Neurosci. 28, 9870-9879
    • (2008) J. Neurosci. , vol.28 , pp. 9870-9879
    • Volosin, M.1    Trotter, C.2    Cragnolini, A.3    Kenchappa, R.S.4    Light, M.5    Hempstead, B.L.6    Carter, B.D.7    Friedman, W.J.8
  • 20
    • 80054678078 scopus 로고    scopus 로고
    • Roles of p75NTR in the pathogenesis of Alzheimer's disease: A novel therapeutic target
    • Zeng, F., Lu, J. J., Zhou, X. F., and Wang, Y. J. (2011) Roles of p75NTR in the pathogenesis of Alzheimer's disease: a novel therapeutic target. Biochem. Pharmacol. 82, 1500-1509
    • (2011) Biochem. Pharmacol. , vol.82 , pp. 1500-1509
    • Zeng, F.1    Lu, J.J.2    Zhou, X.F.3    Wang, Y.J.4
  • 21
    • 0142241350 scopus 로고    scopus 로고
    • Antisense peptide nucleic acid-mediated knockdown of the p75 neurotrophin receptor delays motor neuron disease in mutant SOD1 transgenic mice
    • DOI 10.1046/j.1471-4159.2003.02053.x
    • Turner, B. J., Cheah, I. K., Macfarlane, K. J., Lopes, E. C., Petratos, S., Langford, S. J., and Cheema, S. S. (2003) Antisense peptide nucleic acid-mediated knockdown of the p75 neurotrophin receptor delays motor neuron disease in mutant SOD1 transgenic mice. J. Neurochem. 87, 752-763 (Pubitemid 37310640)
    • (2003) Journal of Neurochemistry , vol.87 , Issue.3 , pp. 752-763
    • Turner, B.J.1    Cheah, I.K.2    Macfarlane, K.J.3    Lopes, E.C.4    Petratos, S.5    Langford, S.J.6    Cheema, S.S.7
  • 22
    • 0031981458 scopus 로고    scopus 로고
    • Focal cerebral ischemia in rats induces expression of p75 neurotrophin receptor in resistant striatal cholinergic neurons
    • DOI 10.1016/S0306-4522(97)00579-4, PII S0306452297005794
    • Kokaia, Z., Andsberg, G., Martinez-Serrano, A., and Lindvall, O. (1998) Focal cerebral ischemia in rats induces expression of P75 neurotrophin receptor in resistant striatal cholinergic neurons. Neuroscience 84, 1113-1125 (Pubitemid 28157027)
    • (1998) Neuroscience , vol.84 , Issue.4 , pp. 1113-1125
    • Kokaia, Z.1    Andsberg, G.2    Martinez-Serrano, A.3    Lindvall, O.4
  • 23
    • 0037174774 scopus 로고    scopus 로고
    • Expression of the p75 neurotrophin receptor by striatal cholinergic neurons following global ischemia in rats is associated with neuronal degeneration
    • Greferath, U., Mallard, C., Roufail, E., Rees, S. M., Barrett, G. L., and Bartlett, P. F. (2002) Expression of the p75 neurotrophin receptor by striatal cholinergic neurons following global ischemia in rats is associated with neuronal degeneration. Neurosci. Lett. 332, 57-60
    • (2002) Neurosci. Lett. , vol.332 , pp. 57-60
    • Greferath, U.1    Mallard, C.2    Roufail, E.3    Rees, S.M.4    Barrett, G.L.5    Bartlett, P.F.6
  • 28
    • 84875696199 scopus 로고    scopus 로고
    • Neuronal oxidative stress in acute ischemic stroke: Sources and contribution to cell injury
    • Manzanero, S., Santro, T., and Arumugam, T. V. (2013) Neuronal oxidative stress in acute ischemic stroke: sources and contribution to cell injury. Neurochem. Int. 62, 712-718
    • (2013) Neurochem. Int. , vol.62 , pp. 712-718
    • Manzanero, S.1    Santro, T.2    Arumugam, T.V.3
  • 29
    • 84885388816 scopus 로고    scopus 로고
    • The impact of reactive oxygen species and genetic mitochondrial mutations in Parkinson's disease
    • Zuo, L., and Motherwell, M. S. (2013) The impact of reactive oxygen species and genetic mitochondrial mutations in Parkinson's disease. Gene 532, 18-23
    • (2013) Gene , vol.532 , pp. 18-23
    • Zuo, L.1    Motherwell, M.S.2
  • 30
    • 67649772111 scopus 로고    scopus 로고
    • The role of mitochondrial transition pore, and its modulation, in traumatic brain injury and delayed neurodegeneration after TBI
    • Mazzeo, A. T., Beat, A., Singh, A., and Bullock, M. R. (2009) The role of mitochondrial transition pore, and its modulation, in traumatic brain injury and delayed neurodegeneration after TBI. Exp. Neurol. 218, 363-370
    • (2009) Exp. Neurol. , vol.218 , pp. 363-370
    • Mazzeo, A.T.1    Beat, A.2    Singh, A.3    Bullock, M.R.4
  • 31
    • 84874303866 scopus 로고    scopus 로고
    • Impaired transcription in Alzheimer's disease: Key role in mitochondrial dysfunction and oxidative stress
    • Caldeira, G. L., Ferreira, I. L., and Rego, A. C. (2013) Impaired transcription in Alzheimer's disease: key role in mitochondrial dysfunction and oxidative stress. J. Alzheimers Dis. 34, 115-131
    • (2013) J. Alzheimers Dis. , vol.34 , pp. 115-131
    • Caldeira, G.L.1    Ferreira, I.L.2    Rego, A.C.3
  • 32
    • 84887620267 scopus 로고    scopus 로고
    • Cell death and diseases related to oxidative stress: 4-hydroxynonenal (HNE) in the balance
    • Dalleau, S., Baradat, M., Guéraud, F., and Huc, L. (2013) Cell death and diseases related to oxidative stress: 4-hydroxynonenal (HNE) in the balance. Cell Death Differ. 20, 1615-1630
    • (2013) Cell Death Differ. , vol.20 , pp. 1615-1630
    • Dalleau, S.1    Baradat, M.2    Guéraud, F.3    Huc, L.4
  • 33
    • 84866848255 scopus 로고    scopus 로고
    • 4-Hydroxy-2-nonenal, a reactive product of lipid peroxidation, and neurodegenerative diseases: A toxic combination illuminated by redox proteomics studies
    • Perluigi, M., Coccia, R., and Butterfield, D. A. (2012) 4-Hydroxy-2-nonenal, a reactive product of lipid peroxidation, and neurodegenerative diseases: a toxic combination illuminated by redox proteomics studies. Antioxid. Redox Signal. 17, 1590-1609
    • (2012) Antioxid. Redox Signal. , vol.17 , pp. 1590-1609
    • Perluigi, M.1    Coccia, R.2    Butterfield, D.A.3
  • 34
    • 0030986669 scopus 로고    scopus 로고
    • Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis
    • Kruman, I., Bruce-Keller, A. J., Bredesen, D., Waeg, G., and Mattson, M. P. (1997) Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis. J. Neurosci. 17, 5089-5100 (Pubitemid 27263822)
    • (1997) Journal of Neuroscience , vol.17 , Issue.13 , pp. 5089-5100
    • Kruman, I.1    Bruce-Keller, A.J.2    Bredesen, D.3    Waeg, G.4    Mattson, M.P.5
  • 35
    • 45249124663 scopus 로고    scopus 로고
    • 4-Hydroxynonenal: A membrane lipid oxidation product of medicinal interest
    • DOI 10.1002/med.20117
    • Poli, G., Schaur, R. J., Siems, W. G., and Leonarduzzi, G. (2008) 4-Hydroxynonenal: a membrane lipid oxidation product of medicinal interest. Med. Res. Rev. 28, 569-631 (Pubitemid 351842143)
    • (2008) Medicinal Research Reviews , vol.28 , Issue.4 , pp. 569-631
    • Poli, G.1    Schaur, R.J.2    Siems, W.G.3    Leonarduzzi, G.4
  • 36
    • 0033593225 scopus 로고    scopus 로고
    • Activation of stress signaling pathways by the end product of lipid peroxidation: 4-Hydroxy-2-nonenal is a potential inducer of intracellular peroxide production
    • Uchida, K., Shiraishi, M., Naito, Y., Torii, Y., Nakamura, Y., and Osawa, T. (1999) Activation of stress signaling pathways by the end product of lipid peroxidation: 4-hydroxy-2-nonenal is a potential inducer of intracellular peroxide production. J. Biol. Chem. 274, 2234-2242
    • (1999) J. Biol. Chem. , vol.274 , pp. 2234-2242
    • Uchida, K.1    Shiraishi, M.2    Naito, Y.3    Torii, Y.4    Nakamura, Y.5    Osawa, T.6
  • 37
    • 2342653588 scopus 로고    scopus 로고
    • Resveratrol protects against 4-HNE induced oxidative stress and apoptosis in Swiss 3T3 fibroblasts
    • Kutuk, O., Adli, M., Poli, G., and Basaga, H. (2004) Resveratrol protects against 4-HNE induced oxidative stress and apoptosis in Swiss 3T3 fibroblasts. Biofactors 20, 1-10 (Pubitemid 38586205)
    • (2004) BioFactors , vol.20 , Issue.1 , pp. 1-10
    • Kutuk, O.1    Adli, M.2    Poli, G.3    Basaga, H.4
  • 39
    • 33748809208 scopus 로고    scopus 로고
    • 4-Hydroxynonenal induces vascular smooth muscle cell apoptosis through mitochondrial generation of reactive oxygen species
    • DOI 10.1016/j.toxlet.2006.07.305, PII S0378427406011581
    • Lee, J. Y., Jung, G. Y., Heo, H. J., Yun, M. R., Park, J. Y., Bae, S. S., Hong, K. W., Lee, W. S., and Kim, C. D. (2006) 4-Hydroxynonenal induces vascular smooth muscle cell apoptosis through mitochondrial generation of reactive oxygen species. Toxicol. Lett. 166, 212-221 (Pubitemid 44416551)
    • (2006) Toxicology Letters , vol.166 , Issue.3 , pp. 212-221
    • Lee, J.Y.1    Jung, G.Y.2    Heo, H.J.3    Yun, M.R.4    Park, J.Y.5    Bae, S.S.6    Hong, K.W.7    Lee, W.S.8    Kim, C.D.9
  • 40
    • 84859821743 scopus 로고    scopus 로고
    • Use of PC12 cells and rat superior cervical ganglion sympathetic neurons as models for neuroprotective assays relevant to Parkinson's disease
    • Grau, C. M., and Greene, L. A. (2012) Use of PC12 cells and rat superior cervical ganglion sympathetic neurons as models for neuroprotective assays relevant to Parkinson's disease. Methods Mol. Biol. 846, 201-211
    • (2012) Methods Mol. Biol. , vol.846 , pp. 201-211
    • Grau, C.M.1    Greene, L.A.2
  • 41
    • 33751224470 scopus 로고    scopus 로고
    • Convenient and efficient syntheses of 4-hydroxy-2(E)-nonenal and 4-oxo-2(E)-nonenal
    • DOI 10.1007/s11745-006-5043-4
    • Kurangi, R. F., Tilve, S. G., and Blair, I. A. (2006) Convenient and efficient syntheses of 4-hydroxy-2(E)-nonenal and 4-oxo-2(E)-nonenal. Lipids 41, 877-880 (Pubitemid 44788909)
    • (2006) Lipids , vol.41 , Issue.9 , pp. 877-880
    • Kurangi, R.F.1    Tilve, S.G.2    Blair, I.A.3
  • 42
    • 0036322302 scopus 로고    scopus 로고
    • c-jun is essential for sympathetic neuronal death induced by NGF withdrawal but not by p75 activation
    • DOI 10.1083/jcb.200112129
    • Palmada, M., Kanwal, S., Rutkoski, N. J., Gustafson-Brown, C., Johnson, R. S., Wisdom, R., and Carter, B. D. (2002) C-jun is essential for sympathetic neuronal death induced by NGF withdrawal but not by p75 activation. J. Cell Biol. 158, 453-461 (Pubitemid 34851704)
    • (2002) Journal of Cell Biology , vol.158 , Issue.3 , pp. 453-461
    • Palmada, M.1    Kanwal, S.2    Rutkoski, N.J.3    Gufstafson-Brown, C.4    Johnson, R.S.5    Wisdom, R.6    Carter, B.D.7
  • 43
    • 65649126738 scopus 로고    scopus 로고
    • Nicotinamide mononucleotide adenylyl transferase-mediated axonal protection requires enzymatic activity but not increased levels of neuronal nicotinamide adenine dinucleotide
    • Sasaki, Y., Vohra, B. P., Lund, F. E., and Milbrandt, J. (2009) Nicotinamide mononucleotide adenylyl transferase-mediated axonal protection requires enzymatic activity but not increased levels of neuronal nicotinamide adenine dinucleotide. J. Neurosci. 29, 5525-5535
    • (2009) J. Neurosci. , vol.29 , pp. 5525-5535
    • Sasaki, Y.1    Vohra, B.P.2    Lund, F.E.3    Milbrandt, J.4
  • 45
    • 80051519518 scopus 로고    scopus 로고
    • Image-based screening identifies novel roles for IκB kinase and glycogen synthase kinase 3 in axonal degeneration
    • Gerdts, J., Sasaki, Y., Vohra, B., Marasa, J., and Milbrandt, J. (2011) Image-based screening identifies novel roles for IκB kinase and glycogen synthase kinase 3 in axonal degeneration. J. Biol. Chem. 286, 28011-28018
    • (2011) J. Biol. Chem. , vol.286 , pp. 28011-28018
    • Gerdts, J.1    Sasaki, Y.2    Vohra, B.3    Marasa, J.4    Milbrandt, J.5
  • 46
    • 0026567360 scopus 로고
    • Pharmacological characterization of dopamine systems in the nucleus accumbens core and shell
    • Deutch, A. Y., and Cameron, D. S. (1992) Pharmacological characterization of dopamine systems in the nucleus accumbens core and shell. Neuroscience 46, 49-56
    • (1992) Neuroscience , vol.46 , pp. 49-56
    • Deutch, A.Y.1    Cameron, D.S.2
  • 47
    • 0036893515 scopus 로고    scopus 로고
    • JNK3 contributes to c-jun induction and apoptosis in 4-hydroxynonenal- treated sympathetic neurons
    • DOI 10.1002/jnr.10437
    • Bruckner, S. R., and Estus, S. (2002) JNK3 contributes to c-jun induction and apoptosis in 4-hydroxynonenal-treated sympathetic neurons. J. Neurosci. Res. 70, 665-670 (Pubitemid 35397140)
    • (2002) Journal of Neuroscience Research , vol.70 , Issue.5 , pp. 665-670
    • Bruckner, S.R.1    Estus, S.2
  • 48
    • 0034524859 scopus 로고    scopus 로고
    • Human studies related to protein oxidation: Protein carbonyl content as a marker of damage
    • Chevion, M., Berenshtein, E., and Stadtman, E. R. (2000) Human studies related to protein oxidation: protein carbonyl content as a marker of damage. Free Radic. Res. 33, S99-108
    • (2000) Free Radic. Res. , vol.33
    • Chevion, M.1    Berenshtein, E.2    Stadtman, E.R.3
  • 49
    • 84879799811 scopus 로고    scopus 로고
    • Axonal degeneration in the peripheral nervous system: Implications for the pathogenesis of amyotrophic lateral sclerosis
    • Fischer-Hayes, L. R., Brotherton, T., and Glass, J. D. (2013) Axonal degeneration in the peripheral nervous system: implications for the pathogenesis of amyotrophic lateral sclerosis. Exp. Neurol. 246, 6-13
    • (2013) Exp. Neurol. , vol.246 , pp. 6-13
    • Fischer-Hayes, L.R.1    Brotherton, T.2    Glass, J.D.3
  • 50
    • 84897437047 scopus 로고    scopus 로고
    • Pathogenesis of synaptic degeneration in Alzheimer's disease and Lewy body disease
    • Overk, C. R., and Masliah, E. (2014) Pathogenesis of synaptic degeneration in Alzheimer's disease and Lewy body disease. Biochem. Pharmacol. 88, 508-516
    • (2014) Biochem. Pharmacol. , vol.88 , pp. 508-516
    • Overk, C.R.1    Masliah, E.2
  • 51
    • 84878586685 scopus 로고    scopus 로고
    • The Phr1 ubiquitin ligase promotes injury-induced axon self-destruction
    • Babetto, E., Beirowski, B., Russler, E. V., Milbrandt, J., and DiAntonio, A. (2013) The Phr1 ubiquitin ligase promotes injury-induced axon self-destruction. Cell Rep. 3, 1422-1429
    • (2013) Cell Rep. , vol.3 , pp. 1422-1429
    • Babetto, E.1    Beirowski, B.2    Russler, E.V.3    Milbrandt, J.4    DiAntonio, A.5
  • 52
    • 0031039772 scopus 로고    scopus 로고
    • Synaptic innervation density is regulated by neuron-derived BDNF
    • DOI 10.1016/S0896-6273(00)80266-4
    • Causing, C. G., Gloster, A., Aloyz, R., Bamji, S. X., Chang, E., Fawcett, J., Kuchel, G., and Miller, F. D. (1997) Synaptic innervation density is regulated by neuron-derived BDNF. Neuron 18, 257-267 (Pubitemid 27111108)
    • (1997) Neuron , vol.18 , Issue.2 , pp. 257-267
    • Causing, C.G.1    Gloster, A.2    Aloyz, R.3    Bamji, S.X.4    Chang, E.5    Fawcett, J.6    Kuchel, G.7    Miller, F.D.8
  • 53
    • 42349090693 scopus 로고    scopus 로고
    • A model for neuronal competition during development
    • DOI 10.1126/science.1152677
    • Deppmann, C. D., Mihalas, S., Sharma, N., Lonze, B. E., Niebur, E., and Ginty, D. D. (2008) A model for neuronal competition during development. Science 320, 369-373 (Pubitemid 351555658)
    • (2008) Science , vol.320 , Issue.5874 , pp. 369-373
    • Deppmann, C.D.1    Mihalas, S.2    Sharma, N.3    Lonze, B.E.4    Niebur, E.5    Ginty, D.D.6
  • 54
    • 0035976524 scopus 로고    scopus 로고
    • Regulation of cell survival by secreted proneurotrophins
    • DOI 10.1126/science.1065057
    • Lee, R., Kermani, P., Teng, K. K., and Hempstead, B. L. (2001) Regulation of cell survival by secreted proneurotrophins. Science 294, 1945-1948 (Pubitemid 33101595)
    • (2001) Science , vol.294 , Issue.5548 , pp. 1945-1948
    • Lee, R.1    Kermani, P.2    Teng, K.K.3    Hempstead, B.L.4
  • 55
    • 76549235314 scopus 로고
    • Selective growth stimulating effects of mouse sarcoma on the sensory and sympathetic nervous system of the chick embryo
    • Levi-Montalcini, R., and Hamburger, V. (1951) Selective growth stimulating effects of mouse sarcoma on the sensory and sympathetic nervous system of the chick embryo. J. Exp. Zool. 116, 321-361
    • (1951) J. Exp. Zool. , vol.116 , pp. 321-361
    • Levi-Montalcini, R.1    Hamburger, V.2
  • 56
    • 0001047311 scopus 로고
    • Purification of a nerve-growth promoting protein from the mouse salivary gland and its neuro-cytotoxic antiserum
    • Cohen, S. (1960) Purification of a nerve-growth promoting protein from the mouse salivary gland and its neuro-cytotoxic antiserum. Proc. Natl. Acad. Sci. U.S.A. 46, 302-311
    • (1960) Proc. Natl. Acad. Sci. U.S.A. , vol.46 , pp. 302-311
    • Cohen, S.1
  • 57
    • 84905396442 scopus 로고    scopus 로고
    • NGF, BDNF, NT3, and NT4
    • Bothwell, M. (2014) NGF, BDNF, NT3, and NT4. Handb. Exp. Pharmacol. 220, 3-15
    • (2014) Handb. Exp. Pharmacol. , vol.220 , pp. 3-15
    • Bothwell, M.1
  • 58
    • 84860615324 scopus 로고    scopus 로고
    • Neurotoxin-based models of Parkinson's disease
    • Bové, J., and Perier, C. (2012) Neurotoxin-based models of Parkinson's disease. Neuroscience 211, 51-76
    • (2012) Neuroscience , vol.211 , pp. 51-76
    • Bové, J.1    Perier, C.2
  • 59
    • 0014415255 scopus 로고
    • An electron microscopic study of selective, acute degeneration of sympathetic nerve terminals after administration of 6-hydroxydopamine
    • Tranzer, J. P., and Thoenen, H. (1968) An electron microscopic study of selective, acute degeneration of sympathetic nerve terminals after administration of 6-hydroxydopamine. Experientia 24, 155-156
    • (1968) Experientia , vol.24 , pp. 155-156
    • Tranzer, J.P.1    Thoenen, H.2
  • 60
    • 0014709463 scopus 로고
    • Sympathetic nerve cell destruction in newborn mammals by 6-hydroxydopamine
    • Angeletti, P. U., and Levi-Montalcini, R. (1970) Sympathetic nerve cell destruction in newborn mammals by 6-hydroxydopamine. Proc. Natl. Acad. Sci. U.S.A. 65, 114-121
    • (1970) Proc. Natl. Acad. Sci. U.S.A. , vol.65 , pp. 114-121
    • Angeletti, P.U.1    Levi-Montalcini, R.2
  • 61
    • 0015020955 scopus 로고
    • Model experiments on the molecular mechanism of action of 6-hydroxydopamine
    • Saner, A., and Thoenen, H. (1971) Model experiments on the molecular mechanism of action of 6-hydroxydopamine. Mol. Pharmacol. 7, 147-154
    • (1971) Mol. Pharmacol. , vol.7 , pp. 147-154
    • Saner, A.1    Thoenen, H.2
  • 62
    • 0016378870 scopus 로고
    • The generation of hydrogen peroxide, superoxide radical, and hydroxyl radical by 6-hydroxydopamine, dialuric acid, and related cytotoxic agents
    • Cohen, G., and Heikkila, R. E. (1974) The generation of hydrogen peroxide, superoxide radical, and hydroxyl radical by 6-hydroxydopamine, dialuric acid, and related cytotoxic agents. J. Biol. Chem. 249, 2447-2452
    • (1974) J. Biol. Chem. , vol.249 , pp. 2447-2452
    • Cohen, G.1    Heikkila, R.E.2
  • 63
    • 64749085056 scopus 로고    scopus 로고
    • Elevated P75NTR expression causes death of engrailed-deficient midbrain dopaminergic neurons by Erk1/2 suppression
    • Alavian, K. N., Sgadò, P., Alberi, L., Subramaniam, S., and Simon, H. H. (2009) Elevated P75NTR expression causes death of engrailed-deficient midbrain dopaminergic neurons by Erk1/2 suppression. Neural Dev. 4, 11
    • (2009) Neural Dev. , vol.4 , pp. 11
    • Alavian, K.N.1    Sgadò, P.2    Alberi, L.3    Subramaniam, S.4    Simon, H.H.5
  • 64
    • 84880170272 scopus 로고    scopus 로고
    • Neurofibrillary tangles in the peripheral sympathetic ganglia of patients with myotonic dystrophy
    • Kuru, S., Sakai, M., Yoshida, M., Mimuro, M., and Hashizume, Y. (2013) Neurofibrillary tangles in the peripheral sympathetic ganglia of patients with myotonic dystrophy. Neuropathol. Appl. Neurobiol. 39, 585-588
    • (2013) Neuropathol. Appl. Neurobiol. , vol.39 , pp. 585-588
    • Kuru, S.1    Sakai, M.2    Yoshida, M.3    Mimuro, M.4    Hashizume, Y.5
  • 65
    • 77953033188 scopus 로고    scopus 로고
    • Involvement of the peripheral nervous system in synucleinopathies, tauopathies and other neurodegenerative proteinopathies of the brain
    • Wakabayashi, K., Mori, F., Tanji, K., Orimo, S., and Takahashi, H. (2010) Involvement of the peripheral nervous system in synucleinopathies, tauopathies and other neurodegenerative proteinopathies of the brain. Acta Neuropathol. 120, 1-12
    • (2010) Acta Neuropathol. , vol.120 , pp. 1-12
    • Wakabayashi, K.1    Mori, F.2    Tanji, K.3    Orimo, S.4    Takahashi, H.5
  • 66
    • 77953022918 scopus 로고    scopus 로고
    • Lewy pathology in the submandibular gland of individuals with incidental Lewy body disease and sporadic Parkinson's disease
    • Del Tredici, K., Hawkes, C. H., Ghebremedhin, E., and Braak, H. (2010) Lewy pathology in the submandibular gland of individuals with incidental Lewy body disease and sporadic Parkinson's disease. Acta Neuropathol. 119, 703-713
    • (2010) Acta Neuropathol. , vol.119 , pp. 703-713
    • Del Tredici, K.1    Hawkes, C.H.2    Ghebremedhin, E.3    Braak, H.4
  • 67
    • 39749123263 scopus 로고    scopus 로고
    • Axonal α-synuclein aggregates herald centripetal degeneration of cardiac sympathetic nerve in Parkinson's disease
    • DOI 10.1093/brain/awm302
    • Orimo, S., Uchihara, T., Nakamura, A., Mori, F., Kakita, A., Wakabayashi, K., and Takahashi, H. (2008) Axonal α-synuclein aggregates herald centripetal degeneration of cardiac sympathetic nerve in Parkinson's disease. Brain 131, 642-650 (Pubitemid 351294710)
    • (2008) Brain , vol.131 , Issue.3 , pp. 642-650
    • Orimo, S.1    Uchihara, T.2    Nakamura, A.3    Mori, F.4    Kakita, A.5    Wakabayashi, K.6    Takahashi, H.7
  • 68
    • 33646082266 scopus 로고    scopus 로고
    • α-Synuclein pathology of the spinal and peripheral autonomic nervous system in neurologically unimpaired elderly subjects
    • Bloch, A., Probst, A., Bissig, H., Adams, H., and Tolnay, M. (2006) α-Synuclein pathology of the spinal and peripheral autonomic nervous system in neurologically unimpaired elderly subjects. Neuropathol. Appl. Neurobiol. 32, 284-295
    • (2006) Neuropathol. Appl. Neurobiol. , vol.32 , pp. 284-295
    • Bloch, A.1    Probst, A.2    Bissig, H.3    Adams, H.4    Tolnay, M.5
  • 69
    • 48349086088 scopus 로고    scopus 로고
    • Identification and kainic acid-induced up-regulation of low-affinity p75 neurotrophin receptor (p75NTR) in the nigral dopamine neurons of adult rats
    • Wang, Y. Q., Bian, G. L., Bai, Y., Cao, R., and Chen, L. W. (2008) Identification and kainic acid-induced up-regulation of low-affinity p75 neurotrophin receptor (p75NTR) in the nigral dopamine neurons of adult rats. Neurochem. Int. 53, 56-62
    • (2008) Neurochem. Int. , vol.53 , pp. 56-62
    • Wang, Y.Q.1    Bian, G.L.2    Bai, Y.3    Cao, R.4    Chen, L.W.5
  • 71
    • 84862312999 scopus 로고    scopus 로고
    • Astrocyte immune responses in epilepsy
    • Aronica, E., Ravizza, T., Zurolo, E., and Vezzani, A. (2012) Astrocyte immune responses in epilepsy. Glia 60, 1258-1268
    • (2012) Glia , vol.60 , pp. 1258-1268
    • Aronica, E.1    Ravizza, T.2    Zurolo, E.3    Vezzani, A.4
  • 72
    • 84874663092 scopus 로고    scopus 로고
    • Roles of activated microglia in hypoxia induced neuroinflammation in the developing brain and the retina
    • Kaur, C., Rathnasamy, G., and Ling, E. A. (2013) Roles of activated microglia in hypoxia induced neuroinflammation in the developing brain and the retina. J. Neuroimmune Pharmacol. 8, 66-78
    • (2013) J. Neuroimmune Pharmacol. , vol.8 , pp. 66-78
    • Kaur, C.1    Rathnasamy, G.2    Ling, E.A.3
  • 73
    • 70449425925 scopus 로고    scopus 로고
    • Inflammatory cytokines IL-1β and TNF-α regulate p75NTR expression in CNS neurons and astrocytes by distinct cell-type-specific signalling mechanisms
    • Choi, S., and Friedman, W. J. (2009) Inflammatory cytokines IL-1β and TNF-α regulate p75NTR expression in CNS neurons and astrocytes by distinct cell-type-specific signalling mechanisms. ASN Neuro 1, e00010
    • (2009) ASN Neuro , vol.1
    • Choi, S.1    Friedman, W.J.2
  • 74
    • 84888422685 scopus 로고    scopus 로고
    • Interleukin-1β enhances neuronal vulnerability to proNGF-mediated apoptosis by increasing surface expression of p75(NTR) and sortillin
    • Choi, S., and Friedman, W. J. (2014) Interleukin-1β enhances neuronal vulnerability to proNGF-mediated apoptosis by increasing surface expression of p75(NTR) and sortillin. Neuroscience 257, 11-19
    • (2014) Neuroscience , vol.257 , pp. 11-19
    • Choi, S.1    Friedman, W.J.2
  • 76
    • 0034730639 scopus 로고    scopus 로고
    • Chopper, a new death domain of the p75 neurotrophin receptor that mediates rapid neuronal cell death
    • Coulson, E. J., Reid, K., Baca, M., Shipham, K. A., Hulett, S. M., Kilpatrick, T. J., and Bartlett, P. F. (2000) Chopper, a new death domain of the p75 neurotrophin receptor that mediates rapid neuronal cell death. J. Biol. Chem. 275, 30537-30545
    • (2000) J. Biol. Chem. , vol.275 , pp. 30537-30545
    • Coulson, E.J.1    Reid, K.2    Baca, M.3    Shipham, K.A.4    Hulett, S.M.5    Kilpatrick, T.J.6    Bartlett, P.F.7
  • 78
    • 0035933783 scopus 로고    scopus 로고
    • The p75 neurotrophin receptor activates Akt (protein kinase B) through a phosphatidylinositol 3-kinase-dependent pathway
    • Roux, P. P., Bhakar, A. L., Kennedy, T. E., and Barker, P. A. (2001) The p75 neurotrophin receptor activates Akt (protein kinase B) through a phosphatidylinositol 3-kinase-dependent pathway. J. Biol. Chem. 276, 23097-23104
    • (2001) J. Biol. Chem. , vol.276 , pp. 23097-23104
    • Roux, P.P.1    Bhakar, A.L.2    Kennedy, T.E.3    Barker, P.A.4
  • 81
    • 0035260351 scopus 로고    scopus 로고
    • Reactive oxygen species mediate tumor necrosis factor α-converting, enzyme-dependent ectodomain shedding induced by phorbol myristate acetate
    • Zhang, Z., Oliver, P., Lancaster, J. R., Jr., Schwarzenberger, P. O., Joshi, M. S., Cork, J., and Kolls, J. K. (2001) Reactive oxygen species mediate tumor necrosis factor α-converting, enzyme-dependent ectodomain shedding induced by phorbol myristate acetate. FASEB J. 15, 303-305
    • (2001) FASEB J. , vol.15 , pp. 303-305
    • Zhang, Z.1    Oliver, P.2    Lancaster Jr., J.R.3    Schwarzenberger, P.O.4    Joshi, M.S.5    Cork, J.6    Kolls, J.K.7
  • 82
    • 61449229249 scopus 로고    scopus 로고
    • Regulation of mature ADAM17 by redox agents for L-selectin shedding
    • Wang, Y., Herrera, A. H., Li, Y., Belani, K. K., and Walcheck, B. (2009) Regulation of mature ADAM17 by redox agents for L-selectin shedding. J. Immunol. 182, 2449-2457
    • (2009) J. Immunol. , vol.182 , pp. 2449-2457
    • Wang, Y.1    Herrera, A.H.2    Li, Y.3    Belani, K.K.4    Walcheck, B.5
  • 83
    • 73849141240 scopus 로고    scopus 로고
    • Mitochondrial reactive oxygen species mediate GPCR-induced TACE/ADAM17-dependent transforming growth factor-α shedding
    • Myers, T. J., Brennaman, L. H., Stevenson, M., Higashiyama, S., Russell, W. E., Lee, D. C., and Sunnarborg, S. W. (2009) Mitochondrial reactive oxygen species mediate GPCR-induced TACE/ADAM17-dependent transforming growth factor-α shedding. Mol. Biol. Cell 20, 5236-5249
    • (2009) Mol. Biol. Cell , vol.20 , pp. 5236-5249
    • Myers, T.J.1    Brennaman, L.H.2    Stevenson, M.3    Higashiyama, S.4    Russell, W.E.5    Lee, D.C.6    Sunnarborg, S.W.7
  • 84
    • 70449732317 scopus 로고    scopus 로고
    • Oxidative stress activates ADAM17/TACE and induces its target receptor shedding in platelets in a p38-dependent fashion
    • Brill, A., Chauhan, A. K., Canault, M., Walsh, M. T., Bergmeier, W., and Wagner, D. D. (2009) Oxidative stress activates ADAM17/TACE and induces its target receptor shedding in platelets in a p38-dependent fashion. Cardiovasc. Res. 84, 137-144
    • (2009) Cardiovasc. Res. , vol.84 , pp. 137-144
    • Brill, A.1    Chauhan, A.K.2    Canault, M.3    Walsh, M.T.4    Bergmeier, W.5    Wagner, D.D.6
  • 85
    • 26944498689 scopus 로고    scopus 로고
    • The intracellular domain of p75NTR as a determinant of cellular reducing potential and response to oxidant stress
    • DOI 10.1111/j.1474-9726.2005.00160.x
    • Tyurina, Y. Y., Nylander, K. D., Mirnics, Z. K., Portugal, C., Yan, C., Zaccaro, C., Saragovi, H. U., Kagan, V. E., and Schor, N. F. (2005) The intracellular domain of p75NTR as a determinant of cellular reducing potential and response to oxidant stress. Aging Cell 4, 187-196 (Pubitemid 41602740)
    • (2005) Aging Cell , vol.4 , Issue.4 , pp. 187-196
    • Tyurina, Y.Y.1    Nylander, K.D.2    Mirnics, Z.K.3    Portugal, C.4    Yan, C.5    Zaccaro, C.6    Saragovi, H.U.7    Kagan, V.E.8    Schor, N.F.9
  • 86
    • 77954367715 scopus 로고    scopus 로고
    • The p75NTR intracellular domain generated by neurotrophin-induced receptor cleavage potentiates Trk signaling
    • Ceni, C., Kommaddi, R. P., Thomas, R., Vereker, E., Liu, X., McPherson, P. S., Ritter, B., and Barker, P. A. (2010) The p75NTR intracellular domain generated by neurotrophin-induced receptor cleavage potentiates Trk signaling. J. Cell Sci. 123, 2299-2307
    • (2010) J. Cell Sci. , vol.123 , pp. 2299-2307
    • Ceni, C.1    Kommaddi, R.P.2    Thomas, R.3    Vereker, E.4    Liu, X.5    McPherson, P.S.6    Ritter, B.7    Barker, P.A.8
  • 87
    • 0015546165 scopus 로고
    • The pharmacology of 6-hydroxydopamine
    • Thoenen, H., and Tranzer, J. P. (1973) The pharmacology of 6-hydroxydopamine. Annu. Rev. Pharmacol. 13, 169-180
    • (1973) Annu. Rev. Pharmacol. , vol.13 , pp. 169-180
    • Thoenen, H.1    Tranzer, J.P.2


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