메뉴 건너뛰기




Volumn 29, Issue 17, 2009, Pages 5525-5535

Nicotinamide mononucleotide adenylyl transferase-mediated axonal protection requires enzymatic activity but not increased levels of neuronal nicotinamide adenine dinucleotide

Author keywords

[No Author keywords available]

Indexed keywords

NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE NUCLEOTIDE ADENYLYLTRANSFERASE; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE;

EID: 65649126738     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5469-08.2009     Document Type: Article
Times cited : (205)

References (47)
  • 1
    • 41749092312 scopus 로고    scopus 로고
    • Reversible compartmentalization of de novo purine biosynthetic complexes in living cells
    • An S, Kumar R, Sheets ED, Benkovic SJ (2008) Reversible compartmentalization of de novo purine biosynthetic complexes in living cells. Science 320:103-106.
    • (2008) Science , vol.320 , pp. 103-106
    • An, S.1    Kumar, R.2    Sheets, E.D.3    Benkovic, S.J.4
  • 2
    • 4043165678 scopus 로고    scopus 로고
    • Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration
    • DOI 10.1126/science.1098014
    • Araki T, Sasaki Y, Milbrandt J (2004) Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration. Science 305:1010-1013. (Pubitemid 39071777)
    • (2004) Science , vol.305 , Issue.5686 , pp. 1010-1013
    • Araki, T.1    Sasaki, Y.2    Milbrandt, J.3
  • 3
    • 27744501798 scopus 로고    scopus 로고
    • Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms
    • DOI 10.1074/jbc.M508660200
    • Berger F, Lau C, Dahlmann M, Ziegler M (2005) Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms. J Biol Chem 280:36334-36341. (Pubitemid 41633907)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.43 , pp. 36334-36341
    • Berger, F.1    Lau, C.2    Dahlmann, M.3    Ziegler, M.4
  • 4
    • 2342550554 scopus 로고    scopus 로고
    • + in fungi and humans
    • DOI 10.1016/S0092-8674(04)00416-7, PII S0092867404004167
    • Bieganowski P, Brenner C (2004) Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans. Cell 117:495-502. (Pubitemid 38610234)
    • (2004) Cell , vol.117 , Issue.4 , pp. 495-502
    • Bieganowski, P.1    Brenner, C.2
  • 6
    • 0037083765 scopus 로고    scopus 로고
    • CD38 is the major enzyme responsible for synthesis of nicotinic acid - Adenine dinucleotide phosphate in mammalian tissues
    • DOI 10.1042/0264-6021:3620125
    • Chini EN, Chini CC, Kato I, Takasawa S, Okamoto H (2002) CD38 is the major enzyme responsible for synthesis of nicotinic acid-adenine dinucleotide phosphate in mammalian tissues. Biochem J 362:125-130. (Pubitemid 34174469)
    • (2002) Biochemical Journal , vol.362 , Issue.1 , pp. 125-130
    • Chini, E.N.1    Chini, C.C.S.2    Kato, I.3    Takasawa, S.4    Okamoto, H.5
  • 8
    • 27644591304 scopus 로고    scopus 로고
    • Axon degeneration mechanisms: Commonality amid diversity
    • DOI 10.1038/nrn1788, PII N1788
    • Coleman M (2005) Axon degeneration mechanisms: commonality amid diversity. Nat Rev Neurosci 6:889-898. (Pubitemid 41568730)
    • (2005) Nature Reviews Neuroscience , vol.6 , Issue.11 , pp. 889-898
    • Coleman, M.1
  • 11
    • 39749117439 scopus 로고    scopus 로고
    • Directed mutagenesis using the polymerase chain reaction
    • Cormack B (1997) Directed mutagenesis using the polymerase chain reaction. Curr Protoc Mol Biol 8.5.1-8.5.10.
    • (1997) Curr Protoc Mol Biol
    • Cormack, B.1
  • 12
    • 0034665459 scopus 로고    scopus 로고
    • Structure of nicotinamide mononucleotide adenylyltransferase: A key enzyme in NAD(+) biosynthesis
    • D'Angelo I, Raffaelli N, Dabusti V, Lorenzi T, Magni G, Rizzi M (2000) Structure of nicotinamide mononucleotide adenylyltransferase: a key enzyme in NAD(+) biosynthesis. Structure 8:993-1004.
    • (2000) Structure , vol.8 , pp. 993-1004
    • D'Angelo, I.1    Raffaelli, N.2    Dabusti, V.3    Lorenzi, T.4    Magni, G.5    Rizzi, M.6
  • 14
    • 0037296218 scopus 로고    scopus 로고
    • Identification and characterization of a second NMN adenylyltransferase gene in Saccharomyces cerevisiae
    • Emanuelli M, Amici A, Carnevali F, Pierella F, Raffaelli N, Magni G (2003) Identification and characterization of a second NMN adenylyltransferase gene in Saccharomyces cerevisiae. Protein Expr Purif 27:357-364.
    • (2003) Protein Expr Purif , vol.27 , pp. 357-364
    • Emanuelli, M.1    Amici, A.2    Carnevali, F.3    Pierella, F.4    Raffaelli, N.5    Magni, G.6
  • 16
    • 0242526050 scopus 로고    scopus 로고
    • FK866, a Highly Specific Noncompetitive Inhibitor of Nicotinamide Phosphoribosyltransferase, Represents a Novel Mechanism for Induction of Tumor Cell Apoptosis
    • Hasmann M, Schemainda I (2003) FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis. Cancer Res 63:7436-7442. (Pubitemid 37413486)
    • (2003) Cancer Research , vol.63 , Issue.21 , pp. 7436-7442
    • Hasmann, M.1    Schemainda, I.2
  • 17
    • 33744922406 scopus 로고    scopus 로고
    • s Protection Distinguishes Axon Degeneration following Injury from Naturally Occurring Developmental Pruning
    • DOI 10.1016/j.neuron.2006.05.013, PII S0896627306003801
    • Hoopfer ED, McLaughlin T, Watts RJ, Schuldiner O, O'Leary DD, Luo L (2006) Wlds protection distinguishes axon degeneration following injury from naturally occurring developmental pruning. Neuron 50:883-895. (Pubitemid 43850690)
    • (2006) Neuron , vol.50 , Issue.6 , pp. 883-895
    • Hoopfer, E.D.1    McLaughlin, T.2    Watts, R.J.3    Schuldiner, O.4    O'Leary, D.D.M.5    Luo, L.6
  • 18
    • 33846406104 scopus 로고    scopus 로고
    • s: Essential for Nmnat enzyme activity and axon-protective function
    • DOI 10.1016/j.neulet.2006.11.067, PII S0304394006012377
    • Jia H, Yan T, Feng Y, Zeng C, Shi X, Zhai Q (2007) Identification of a critical site in Wld(s): essential for Nmnat enzyme activity and axon-protective function. Neurosci Lett 413:46-51. (Pubitemid 46149192)
    • (2007) Neuroscience Letters , vol.413 , Issue.1 , pp. 46-51
    • Jia, H.1    Yan, T.2    Feng, Y.3    Zeng, C.4    Shi, X.5    Zhai, Q.6
  • 19
    • 33748908067 scopus 로고    scopus 로고
    • Protecting axonal degeneration by increasing nicotinamide adenine dinucleotide levels in experimental autoimmune encephalomyelitis models
    • DOI 10.1523/JNEUROSCI.2116-06.2006
    • Kaneko S, Wang J, Kaneko M, Yiu G, Hurrell JM, Chitnis T, Khoury SJ, He Z (2006) Protecting axonal degeneration by increasing nicotinamide adenine dinucleotide levels in experimental autoimmune encephalomyelitis models. J Neurosci 26:9794-9804. (Pubitemid 44427718)
    • (2006) Journal of Neuroscience , vol.26 , Issue.38 , pp. 9794-9804
    • Kaneko, S.1    Wang, J.2    Kaneko, M.3    Yiu, G.4    Hurrell, J.M.5    Chitnis, T.6    Khoury, S.J.7    He, Z.8
  • 20
    • 0036468677 scopus 로고    scopus 로고
    • Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors
    • DOI 10.1126/science.1067081
    • Lois C, Hong EJ, Pease S, Brown EJ, Baltimore D (2002) Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors. Science 295:868-872. (Pubitemid 34118370)
    • (2002) Science , vol.295 , Issue.5556 , pp. 868-872
    • Lois, C.1    Hong, E.J.2    Pease, S.3    Brown, E.J.4    Baltimore, D.5
  • 21
    • 33947680687 scopus 로고    scopus 로고
    • Signaling properties of CD38 in the mouse immune system: Enzyme-dependent and -independent roles in immunity
    • DOI 10.2119/2006-00099.Lund
    • Lund FE (2006) Signaling properties of CD38 in the mouse immune system: enzyme-dependent and -independent roles in immunity. Mol Med 12:328-333. (Pubitemid 46489828)
    • (2006) Molecular Medicine , vol.12 , Issue.11-12 , pp. 328-333
    • Lund, F.E.1
  • 22
    • 0024373441 scopus 로고
    • Absence of Wallerian degeneration does not hinder regeneration in peripheral nerve
    • DOI 10.1111/j.1460-9568.1989.tb00771.x
    • Lunn ER, Perry VH, Brown MC, Rosen H, Gordon S (1989) Absence of Wallerian degeneration does not hinder regeneration in peripheral nerve. Eur J Neurosci 1:27-33. (Pubitemid 19142026)
    • (1989) European Journal of Neuroscience , vol.1 , Issue.1 , pp. 27-33
    • Lunn, E.R.1    Perry, V.H.2    Brown, M.C.3    Rosen, H.4    Gordon, S.5
  • 23
    • 33744926927 scopus 로고    scopus 로고
    • The Drosophila cell corpse engulfment receptor draper mediates glial clearance of severed axons
    • MacDonald JM, Beach MG, Porpiglia E, Sheehan AE, Watts RJ, Freeman MR (2006) The Drosophila cell corpse engulfment receptor draper mediates glial clearance of severed axons. Neuron 50:869-881.
    • (2006) Neuron , vol.50 , pp. 869-881
    • MacDonald, J.M.1    Beach, M.G.2    Porpiglia, E.3    Sheehan, A.E.4    Watts, R.J.5    Freeman, M.R.6
  • 26
    • 33748069813 scopus 로고    scopus 로고
    • Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
    • DOI 10.1126/science.1128294
    • Ozcan U, Yilmaz E, Ozcan L, Furuhashi M, Vaillancourt E, Smith RO, Görgün CZ, Hotamisligil GS (2006) Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes. Science 313:1137-1140. (Pubitemid 44300242)
    • (2006) Science , vol.313 , Issue.5790 , pp. 1137-1140
    • Ozcan, U.1    Yilmaz, E.2    Ozcan, L.3    Furuhashi, M.4    Vaillancourt, E.5    Smith, R.O.6    Gorgun, C.Z.7    Hotamisligil, G.S.8
  • 27
    • 0025974211 scopus 로고
    • Very slow retrograde and Wallerian degeneration in the CNS of C57BL/Ola mice
    • Perry VH, Brown MC, Lunn ER (1991) Very slow retrograde and Wallerian degeneration in the CNS of C57BL/Ola mice. Eur J Neurosci 3:102-105.
    • (1991) Eur J Neurosci , vol.3 , pp. 102-105
    • Perry, V.H.1    Brown, M.C.2    Lunn, E.R.3
  • 28
    • 44949233176 scopus 로고    scopus 로고
    • Nmnat delays axonal degeneration caused by mitochondrial and oxidative stress
    • Press C, Milbrandt J (2008) Nmnat delays axonal degeneration caused by mitochondrial and oxidative stress. J Neurosci 28:4861-4871.
    • (2008) J Neurosci , vol.28 , pp. 4861-4871
    • Press, C.1    Milbrandt, J.2
  • 29
    • 0027050148 scopus 로고
    • Recursive PCR: A novel technique for total gene synthesis
    • Prodromou C, Pearl LH (1992) Recursive PCR: a novel technique for total gene synthesis. Protein Eng 5:827-829.
    • (1992) Protein Eng , vol.5 , pp. 827-829
    • Prodromou, C.1    Pearl, L.H.2
  • 30
    • 0037012844 scopus 로고    scopus 로고
    • Axonal self-destruction and neurodegeneration
    • Raff MC, Whitmore AV, Finn JT (2002) Axonal self-destruction and neurodegeneration. Science 296:868-871.
    • (2002) Science , vol.296 , pp. 868-871
    • Raff, M.C.1    Whitmore, A.V.2    Finn, J.T.3
  • 32
    • 10944270187 scopus 로고    scopus 로고
    • The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells
    • DOI 10.1074/jbc.M408388200
    • Revollo JR, Grimm AA, Imai S (2004) The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells. J Biol Chem 279:50754-50763. (Pubitemid 40017813)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.49 , pp. 50754-50763
    • Revollo, J.R.1    Grimm, A.A.2    Imai, S.-I.3
  • 35
    • 33748174151 scopus 로고    scopus 로고
    • Stimulation of nicotinamide adenine dinucleotide biosynthetic pathways delays axonal degeneration after axotomy
    • DOI 10.1523/JNEUROSCI.2320-06.2006
    • Sasaki Y, Araki T, Milbrandt J (2006) Stimulation of nicotinamide adenine dinucleotide biosynthetic pathways delays axonal degeneration after axotomy. J Neurosci 26:8484-8491. (Pubitemid 44316176)
    • (2006) Journal of Neuroscience , vol.26 , Issue.33 , pp. 8484-8491
    • Sasaki, Y.1    Araki, T.2    Milbrandt, J.3
  • 37
    • 30944467113 scopus 로고    scopus 로고
    • A guide to choosing fluorescent proteins
    • DOI 10.1038/nmeth819, PII N819
    • Shaner NC, Steinbach PA, Tsien RY (2005) A guide to choosing fluorescent proteins. Nat Methods 2:905-909. (Pubitemid 43108726)
    • (2005) Nature Methods , vol.2 , Issue.12 , pp. 905-909
    • Shaner, N.C.1    Steinbach, P.A.2    Tsien, R.Y.3
  • 38
    • 34247500849 scopus 로고    scopus 로고
    • + biosynthesis
    • DOI 10.1021/bi6023379
    • Sorci L, Cimadamore F, Scotti S, Petrelli R, Cappellacci L, Franchetti P, Orsomando G, Magni G (2007) Initial-rate kinetics of human NMN- adenylyltransferases: substrate and metal ion specificity, inhibition by products and multisubstrate analogues, and isozyme contributions to NAD+ biosynthesis. Biochemistry 46:4912-4922. (Pubitemid 46651212)
    • (2007) Biochemistry , vol.46 , Issue.16 , pp. 4912-4922
    • Sorci, L.1    Cimadamore, F.2    Scotti, S.3    Petrelli, R.4    Cappellacci, L.5    Franchetti, P.6    Orsomando, G.7    Magni, G.8
  • 39
    • 23744474976 scopus 로고    scopus 로고
    • A local mechanism mediates NAD-dependent protection of axon degeneration
    • DOI 10.1083/jcb.200504028
    • Wang J, Zhai Q, Chen Y, Lin E, Gu W, McBurney MW, He Z (2005) A local mechanism mediates NAD-dependent protection of axon degeneration. J Cell Biol 170:349-355. (Pubitemid 41126935)
    • (2005) Journal of Cell Biology , vol.170 , Issue.3 , pp. 349-355
    • Wang, J.1    Zhai, Q.2    Chen, Y.3    Lin, E.4    Gu, W.5    McBurney, M.W.6    He, Z.7
  • 40
    • 38849146956 scopus 로고    scopus 로고
    • ER and oxidative stresses are common mediators of apoptosis in both neurodegenerative and non-neurodegenerative lysosomal storage disorders and are alleviated by chemical chaperones
    • Wei H, Kim SJ, Zhang Z, Tsai PC, Wisniewski KE, Mukherjee AB (2008) ER and oxidative stresses are common mediators of apoptosis in both neurodegenerative and non-neurodegenerative lysosomal storage disorders and are alleviated by chemical chaperones. Hum Mol Genet 17:469-477.
    • (2008) Hum Mol Genet , vol.17 , pp. 469-477
    • Wei, H.1    Kim, S.J.2    Zhang, Z.3    Tsai, P.C.4    Wisniewski, K.E.5    Mukherjee, A.B.6
  • 41
    • 65649108676 scopus 로고    scopus 로고
    • Differential axonal protection against Wallerian degeneration in vivo is observed in mice overexpressing family members of nicotinamide mononucleotide adenylyltransferase(Nmnat)
    • Yahata N, Araki T (2007) Differential axonal protection against Wallerian degeneration in vivo is observed in mice overexpressing family members of nicotinamide mononucleotide adenylyltransferase(Nmnat). Soc Neurosci Abstr 33:377.20.
    • (2007) Soc Neurosci Abstr , vol.33
    • Yahata, N.1    Araki, T.2
  • 42
    • 0942279500 scopus 로고    scopus 로고
    • Characterization of human brain nicotinamide 5′-mononucleotide adenylyltransferase-2 and expression in human pancreas
    • DOI 10.1042/BJ20030518
    • Yalowitz JA, Xiao S, Biju MP, Antony AC, Cummings OW, Deeg MA, Jayaram HN (2004) Characterization of human brain nicotinamide 5′-mononucleotide adenylyltransferase-2 and expression in human pancreas. Biochem J 377:317-326. (Pubitemid 38142187)
    • (2004) Biochemical Journal , vol.377 , Issue.2 , pp. 317-326
    • Yalowitz, J.A.1    Xiao, S.2    Biju, M.P.3    Antony, A.C.4    Cummings, O.W.5    Deeg, M.A.6    Jayaram, H.N.7
  • 46
    • 42249103603 scopus 로고    scopus 로고
    • NAD synthase NMNAT acts as a chaperone to protect against neurodegeneration
    • Zhai RG, Zhang F, Hiesinger PR, Cao Y, Haueter CM, Bellen HJ (2008) NAD synthase NMNAT acts as a chaperone to protect against neurodegeneration. Nature 452:887-891.
    • (2008) Nature , vol.452 , pp. 887-891
    • Zhai, R.G.1    Zhang, F.2    Hiesinger, P.R.3    Cao, Y.4    Haueter, C.M.5    Bellen, H.J.6
  • 47
    • 0037066769 scopus 로고    scopus 로고
    • Structure of human nicotinamide/nicotinic acid mononucleotide adenylyltransferase. Basis for the dual substrate specificity and activation of the oncolytic agent tiazofurin
    • Zhou T, Kurnasov O, Tomchick DR, Binns DD, Grishin NV, Marquez VE, Osterman AL, Zhang H (2002) Structure of human nicotinamide/nicotinic acid mononucleotide adenylyltransferase. Basis for the dual substrate specificity and activation of the oncolytic agent tiazofurin. J Biol Chem 277:13148-13154.
    • (2002) J Biol Chem , vol.277 , pp. 13148-13154
    • Zhou, T.1    Kurnasov, O.2    Tomchick, D.R.3    Binns, D.D.4    Grishin, N.V.5    Marquez, V.E.6    Osterman, A.L.7    Zhang, H.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.