메뉴 건너뛰기




Volumn 50, Issue 2, 2006, Pages 219-232

Ligand-Dependent Cleavage of the P75 Neurotrophin Receptor Is Necessary for NRIF Nuclear Translocation and Apoptosis in Sympathetic Neurons

Author keywords

CELLBIO; MOLNEURO; SIGNALING

Indexed keywords

DNA; GAMMA SECRETASE; LIGAND; MUTANT PROTEIN; NEUROTROPHIN RECEPTOR; PROTEIN P75;

EID: 33646052860     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuron.2006.03.011     Document Type: Article
Times cited : (163)

References (68)
  • 1
    • 0032559622 scopus 로고    scopus 로고
    • The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron death
    • Bamji S.X., Majdan M., Pozniak C.D., Belliveau D.J., Aloyz R.K., Kohn J., Causing C.G., and Miller F.D. The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron death. J. Cell Biol. 140 (1998) 911-923
    • (1998) J. Cell Biol. , vol.140 , pp. 911-923
    • Bamji, S.X.1    Majdan, M.2    Pozniak, C.D.3    Belliveau, D.J.4    Aloyz, R.K.5    Kohn, J.6    Causing, C.G.7    Miller, F.D.8
  • 2
    • 1942469520 scopus 로고    scopus 로고
    • Death of injured neurons caused by the precursor of nerve growth factor
    • Barde Y.A. Death of injured neurons caused by the precursor of nerve growth factor. Proc. Natl. Acad. Sci. USA 101 (2004) 5703-5704
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 5703-5704
    • Barde, Y.A.1
  • 3
    • 2442463255 scopus 로고    scopus 로고
    • p75NTR is positively promiscuous: novel partners and new insights
    • Barker P.A. p75NTR is positively promiscuous: novel partners and new insights. Neuron 42 (2004) 529-533
    • (2004) Neuron , vol.42 , pp. 529-533
    • Barker, P.A.1
  • 5
    • 5444234359 scopus 로고    scopus 로고
    • Characterization of the c-Jun N-terminal kinase-BimEL signaling pathway in neuronal apoptosis
    • Becker E.B., Howell J., Kodama Y., Barker P.A., and Bonni A. Characterization of the c-Jun N-terminal kinase-BimEL signaling pathway in neuronal apoptosis. J. Neurosci. 24 (2004) 8762-8770
    • (2004) J. Neurosci. , vol.24 , pp. 8762-8770
    • Becker, E.B.1    Howell, J.2    Kodama, Y.3    Barker, P.A.4    Bonni, A.5
  • 8
    • 0037547112 scopus 로고    scopus 로고
    • Ligand-induced internalization of the p75 neurotrophin receptor: a slow route to the signaling endosome
    • Bronfman F.C., Tcherpakov M., Jovin T.M., and Fainzilber M. Ligand-induced internalization of the p75 neurotrophin receptor: a slow route to the signaling endosome. J. Neurosci. 23 (2003) 3209-3220
    • (2003) J. Neurosci. , vol.23 , pp. 3209-3220
    • Bronfman, F.C.1    Tcherpakov, M.2    Jovin, T.M.3    Fainzilber, M.4
  • 9
    • 0035816661 scopus 로고    scopus 로고
    • A transcriptionally active complex of APP with Fe65 and histone acetylase Tip60
    • Cao X., and Sudhof T.C. A transcriptionally active complex of APP with Fe65 and histone acetylase Tip60. Science 293 (2001) 115-120
    • (2001) Science , vol.293 , pp. 115-120
    • Cao, X.1    Sudhof, T.C.2
  • 10
    • 0033231183 scopus 로고    scopus 로고
    • The zinc finger protein NRIF interacts with the neurotrophin receptor p75(NTR) and participates in programmed cell death
    • Casademunt E., Carter B.D., Benzel I., Frade J.M., Dechant G., and Barde Y.A. The zinc finger protein NRIF interacts with the neurotrophin receptor p75(NTR) and participates in programmed cell death. EMBO J. 18 (1999) 6050-6061
    • (1999) EMBO J. , vol.18 , pp. 6050-6061
    • Casademunt, E.1    Carter, B.D.2    Benzel, I.3    Frade, J.M.4    Dechant, G.5    Barde, Y.A.6
  • 11
    • 0346435103 scopus 로고    scopus 로고
    • Generation of the beta-amyloid peptide and the amyloid precursor protein C-terminal fragment gamma are potentiated by FE65L1
    • Chang Y., Tesco G., Jeong W.J., Lindsley L., Eckman E.A., Eckman E.B., Tanzi R.E., and Guenette S.Y. Generation of the beta-amyloid peptide and the amyloid precursor protein C-terminal fragment gamma are potentiated by FE65L1. J. Biol. Chem. 278 (2003) 51100-51107
    • (2003) J. Biol. Chem. , vol.278 , pp. 51100-51107
    • Chang, Y.1    Tesco, G.2    Jeong, W.J.3    Lindsley, L.4    Eckman, E.A.5    Eckman, E.B.6    Tanzi, R.E.7    Guenette, S.Y.8
  • 12
    • 0029021457 scopus 로고
    • p75 and Trk: a two-receptor system
    • Chao M.V., and Hempstead B.L. p75 and Trk: a two-receptor system. Trends Neurosci. 18 (1995) 321-326
    • (1995) Trends Neurosci. , vol.18 , pp. 321-326
    • Chao, M.V.1    Hempstead, B.L.2
  • 13
    • 0032849110 scopus 로고    scopus 로고
    • Identification of a zinc finger protein whose subcellular distribution is regulated by serum and nerve growth factor
    • Chittka A., and Chao M.V. Identification of a zinc finger protein whose subcellular distribution is regulated by serum and nerve growth factor. Proc. Natl. Acad. Sci. USA 96 (1999) 10705-10710
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 10705-10710
    • Chittka, A.1    Chao, M.V.2
  • 14
    • 1842456983 scopus 로고    scopus 로고
    • The p75NTR-interacting protein SC1 inhibits cell cycle progression by transcriptional repression of cyclin E
    • Chittka A., Arevalo J.C., Rodriguez-Guzman M., Perez P., Chao M.V., and Sendtner M. The p75NTR-interacting protein SC1 inhibits cell cycle progression by transcriptional repression of cyclin E. J. Cell Biol. 164 (2004) 985-996
    • (2004) J. Cell Biol. , vol.164 , pp. 985-996
    • Chittka, A.1    Arevalo, J.C.2    Rodriguez-Guzman, M.3    Perez, P.4    Chao, M.V.5    Sendtner, M.6
  • 15
    • 14244268498 scopus 로고    scopus 로고
    • Gamma-secretase exists on the plasma membrane as an intact complex that accepts substrates and effects intramembrane cleavage
    • Chyung J.H., Raper D.M., and Selkoe D.J. Gamma-secretase exists on the plasma membrane as an intact complex that accepts substrates and effects intramembrane cleavage. J. Biol. Chem. 280 (2005) 4383-4392
    • (2005) J. Biol. Chem. , vol.280 , pp. 4383-4392
    • Chyung, J.H.1    Raper, D.M.2    Selkoe, D.J.3
  • 16
    • 0034839287 scopus 로고    scopus 로고
    • The amyloid precursor protein (APP) cytoplasmic fragment generated by gamma-secretase is rapidly degraded but distributes partially in a nuclear fraction of neurons in culture
    • Cupers P., Orlans I., Craessaerts K., Annaert W., and De Strooper B. The amyloid precursor protein (APP) cytoplasmic fragment generated by gamma-secretase is rapidly degraded but distributes partially in a nuclear fraction of neurons in culture. J. Neurochem. 78 (2001) 1168-1178
    • (2001) J. Neurochem. , vol.78 , pp. 1168-1178
    • Cupers, P.1    Orlans, I.2    Craessaerts, K.3    Annaert, W.4    De Strooper, B.5
  • 17
    • 0036830562 scopus 로고    scopus 로고
    • The neurotrophin receptor p75(NTR): novel functions and implications for diseases of the nervous system
    • Dechant G., and Barde Y.A. The neurotrophin receptor p75(NTR): novel functions and implications for diseases of the nervous system. Nat. Neurosci. 5 (2002) 1131-1136
    • (2002) Nat. Neurosci. , vol.5 , pp. 1131-1136
    • Dechant, G.1    Barde, Y.A.2
  • 18
    • 0034644474 scopus 로고    scopus 로고
    • Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain
    • Deng L., Wang C., Spencer E., Yang L., Braun A., You J., Slaughter C., Pickart C., and Chen Z.J. Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain. Cell 103 (2000) 351-361
    • (2000) Cell , vol.103 , pp. 351-361
    • Deng, L.1    Wang, C.2    Spencer, E.3    Yang, L.4    Braun, A.5    You, J.6    Slaughter, C.7    Pickart, C.8    Chen, Z.J.9
  • 19
    • 0021100690 scopus 로고
    • Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
    • Dignam J.D., Lebovitz R.M., and Roeder R.G. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11 (1983) 1475-1489
    • (1983) Nucleic Acids Res. , vol.11 , pp. 1475-1489
    • Dignam, J.D.1    Lebovitz, R.M.2    Roeder, R.G.3
  • 20
    • 0025220956 scopus 로고
    • Regulation of Schwann cell surface and truncated nerve growth factor receptors in vitro by axonal components
    • DiStefano P.S., and Chelsea D.M. Regulation of Schwann cell surface and truncated nerve growth factor receptors in vitro by axonal components. Brain Res. 534 (1990) 340-344
    • (1990) Brain Res. , vol.534 , pp. 340-344
    • DiStefano, P.S.1    Chelsea, D.M.2
  • 21
    • 0027281156 scopus 로고
    • Involvement of a metalloprotease in low-affinity nerve growth factor receptor truncation: inhibition of truncation in vitro and in vivo
    • DiStefano P.S., Chelsea D.M., Schick C.M., and McKelvy J.F. Involvement of a metalloprotease in low-affinity nerve growth factor receptor truncation: inhibition of truncation in vitro and in vivo. J. Neurosci. 13 (1993) 2405-2414
    • (1993) J. Neurosci. , vol.13 , pp. 2405-2414
    • DiStefano, P.S.1    Chelsea, D.M.2    Schick, C.M.3    McKelvy, J.F.4
  • 22
    • 20444365447 scopus 로고    scopus 로고
    • MAG induces regulated intramembrane proteolysis of the p75 neurotrophin receptor to inhibit neurite outgrowth
    • Domeniconi M., Zampieri N., Spencer T., Hilaire M., Mellado W., Chao M.V., and Filbin M.T. MAG induces regulated intramembrane proteolysis of the p75 neurotrophin receptor to inhibit neurite outgrowth. Neuron 46 (2005) 849-855
    • (2005) Neuron , vol.46 , pp. 849-855
    • Domeniconi, M.1    Zampieri, N.2    Spencer, T.3    Hilaire, M.4    Mellado, W.5    Chao, M.V.6    Filbin, M.T.7
  • 24
    • 0037118248 scopus 로고    scopus 로고
    • A RIP tide in neuronal signal transduction
    • Ebinu J.O., and Yankner B.A. A RIP tide in neuronal signal transduction. Neuron 34 (2002) 499-502
    • (2002) Neuron , vol.34 , pp. 499-502
    • Ebinu, J.O.1    Yankner, B.A.2
  • 25
    • 0036727125 scopus 로고    scopus 로고
    • Gamma-secretase-mediated proteolysis in cell-surface-receptor signaling
    • Fortini M.E. Gamma-secretase-mediated proteolysis in cell-surface-receptor signaling. Nat. Rev. Mol. Cell Biol. 3 (2002) 673-684
    • (2002) Nat. Rev. Mol. Cell Biol. , vol.3 , pp. 673-684
    • Fortini, M.E.1
  • 26
    • 13844271798 scopus 로고    scopus 로고
    • Nuclear translocation of the p75 neurotrophin receptor cytoplasmic domain in response to neurotrophin binding
    • Frade J.M. Nuclear translocation of the p75 neurotrophin receptor cytoplasmic domain in response to neurotrophin binding. J. Neurosci. 25 (2005) 1407-1411
    • (2005) J. Neurosci. , vol.25 , pp. 1407-1411
    • Frade, J.M.1
  • 27
    • 0031934936 scopus 로고    scopus 로고
    • Microglia-derived nerve growth factor causes cell death in the developing retina
    • Frade J.M., and Barde Y.A. Microglia-derived nerve growth factor causes cell death in the developing retina. Neuron 20 (1998) 35-41
    • (1998) Neuron , vol.20 , pp. 35-41
    • Frade, J.M.1    Barde, Y.A.2
  • 28
    • 0032968762 scopus 로고    scopus 로고
    • Genetic evidence for cell death mediated by nerve growth factor and the neurotrophin receptor p75 in the developing mouse retina and spinal cord
    • Frade J.M., and Barde Y.A. Genetic evidence for cell death mediated by nerve growth factor and the neurotrophin receptor p75 in the developing mouse retina and spinal cord. Development 126 (1999) 683-690
    • (1999) Development , vol.126 , pp. 683-690
    • Frade, J.M.1    Barde, Y.A.2
  • 29
    • 0029787071 scopus 로고    scopus 로고
    • Induction of cell death by endogenous nerve growth factor through its p75 receptor
    • Frade J.M., Rodriguez-Tebar A., and Barde Y.A. Induction of cell death by endogenous nerve growth factor through its p75 receptor. Nature 383 (1996) 166-168
    • (1996) Nature , vol.383 , pp. 166-168
    • Frade, J.M.1    Rodriguez-Tebar, A.2    Barde, Y.A.3
  • 31
    • 27844442187 scopus 로고    scopus 로고
    • TRAF6 mediated polyubiquitination regulates nuclear translocation of NRIF, the p75 neurotrophin receptor interactor
    • Geetha T., Kenchappa R.S., Wooten M.W., and Carter B.D. TRAF6 mediated polyubiquitination regulates nuclear translocation of NRIF, the p75 neurotrophin receptor interactor. EMBO J. 24 (2005) 3859-3868
    • (2005) EMBO J. , vol.24 , pp. 3859-3868
    • Geetha, T.1    Kenchappa, R.S.2    Wooten, M.W.3    Carter, B.D.4
  • 32
    • 0346849774 scopus 로고    scopus 로고
    • The p75 neurotrophin receptor: multiple interactors and numerous functions
    • Gentry J.J., Barker P.A., and Carter B.D. The p75 neurotrophin receptor: multiple interactors and numerous functions. Prog. Brain Res. 146 (2004) 25-39
    • (2004) Prog. Brain Res. , vol.146 , pp. 25-39
    • Gentry, J.J.1    Barker, P.A.2    Carter, B.D.3
  • 33
    • 1942469321 scopus 로고    scopus 로고
    • A functional interaction between the p75 neurotrophin receptor interacting factors, TRAF6 and NRIF
    • Gentry J.J., Rutkoski N.J., Burke T.L., and Carter B.D. A functional interaction between the p75 neurotrophin receptor interacting factors, TRAF6 and NRIF. J. Biol. Chem. 279 (2004) 16646-16656
    • (2004) J. Biol. Chem. , vol.279 , pp. 16646-16656
    • Gentry, J.J.1    Rutkoski, N.J.2    Burke, T.L.3    Carter, B.D.4
  • 35
    • 0036140118 scopus 로고    scopus 로고
    • Activation of Rac GTPase by p75 is necessary for c-jun N-terminal kinase-mediated apoptosis
    • Harrington A.W., Kim J.Y., and Yoon S.O. Activation of Rac GTPase by p75 is necessary for c-jun N-terminal kinase-mediated apoptosis. J. Neurosci. 22 (2002) 156-166
    • (2002) J. Neurosci. , vol.22 , pp. 156-166
    • Harrington, A.W.1    Kim, J.Y.2    Yoon, S.O.3
  • 38
    • 0038045714 scopus 로고    scopus 로고
    • Proteolytic processing of the p75 neurotrophin receptor and two homologs generates C-terminal fragments with signaling capability
    • Kanning K.C., Hudson M., Amieux P.S., Wiley J.C., Bothwell M., and Schecterson L.C. Proteolytic processing of the p75 neurotrophin receptor and two homologs generates C-terminal fragments with signaling capability. J. Neurosci. 23 (2003) 5425-5436
    • (2003) J. Neurosci. , vol.23 , pp. 5425-5436
    • Kanning, K.C.1    Hudson, M.2    Amieux, P.S.3    Wiley, J.C.4    Bothwell, M.5    Schecterson, L.C.6
  • 39
    • 11144284732 scopus 로고    scopus 로고
    • Notch signaling: a different sort makes the cut
    • Kanwar R., and Fortini M.E. Notch signaling: a different sort makes the cut. Curr. Biol. 14 (2004) R1043-R1045
    • (2004) Curr. Biol. , vol.14
    • Kanwar, R.1    Fortini, M.E.2
  • 40
    • 0033613831 scopus 로고    scopus 로고
    • Association of the p75 neurotrophin receptor with TRAF6
    • Khursigara G., Orlinick J.R., and Chao M.V. Association of the p75 neurotrophin receptor with TRAF6. J. Biol. Chem. 274 (1999) 2597-2600
    • (1999) J. Biol. Chem. , vol.274 , pp. 2597-2600
    • Khursigara, G.1    Orlinick, J.R.2    Chao, M.V.3
  • 41
    • 0347087481 scopus 로고    scopus 로고
    • Necdin-related MAGE proteins differentially interact with the E2F1 transcription factor and the p75 neurotrophin receptor
    • Kuwako K., Taniura H., and Yoshikawa K. Necdin-related MAGE proteins differentially interact with the E2F1 transcription factor and the p75 neurotrophin receptor. J. Biol. Chem. 279 (2004) 1703-1712
    • (2004) J. Biol. Chem. , vol.279 , pp. 1703-1712
    • Kuwako, K.1    Taniura, H.2    Yoshikawa, K.3
  • 42
    • 18844414504 scopus 로고    scopus 로고
    • The roles of receptor and ligand endocytosis in regulating Notch signaling
    • Le Borgne R., Bardin A., and Schweisguth F. The roles of receptor and ligand endocytosis in regulating Notch signaling. Development 132 (2005) 1751-1762
    • (2005) Development , vol.132 , pp. 1751-1762
    • Le Borgne, R.1    Bardin, A.2    Schweisguth, F.3
  • 43
    • 10344238086 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha, interleukin-1beta, and interferon-gamma stimulate gamma-secretase-mediated cleavage of amyloid precursor protein through a JNK-dependent MAPK pathway
    • Liao Y.F., Wang B.J., Cheng H.T., Kuo L.H., and Wolfe M.S. Tumor necrosis factor-alpha, interleukin-1beta, and interferon-gamma stimulate gamma-secretase-mediated cleavage of amyloid precursor protein through a JNK-dependent MAPK pathway. J. Biol. Chem. 279 (2004) 49523-49532
    • (2004) J. Biol. Chem. , vol.279 , pp. 49523-49532
    • Liao, Y.F.1    Wang, B.J.2    Cheng, H.T.3    Kuo, L.H.4    Wolfe, M.S.5
  • 45
    • 0035945344 scopus 로고    scopus 로고
    • TrkA mediates developmental sympathetic neuron survival in vivo by silencing an ongoing p75NTR-mediated death signal
    • Majdan M., Walsh G.S., Aloyz R., and Miller F.D. TrkA mediates developmental sympathetic neuron survival in vivo by silencing an ongoing p75NTR-mediated death signal. J. Cell Biol. 155 (2001) 1275-1285
    • (2001) J. Cell Biol. , vol.155 , pp. 1275-1285
    • Majdan, M.1    Walsh, G.S.2    Aloyz, R.3    Miller, F.D.4
  • 48
    • 0036550661 scopus 로고    scopus 로고
    • Complete deletion of the neurotrophin receptor p75NTR leads to long-lasting increases in the number of basal forebrain cholinergic neurons
    • Naumann T., Casademunt E., Hollerbach E., Hofmann J., Dechant G., Frotscher M., and Barde Y.A. Complete deletion of the neurotrophin receptor p75NTR leads to long-lasting increases in the number of basal forebrain cholinergic neurons. J. Neurosci. 22 (2002) 2409-2418
    • (2002) J. Neurosci. , vol.22 , pp. 2409-2418
    • Naumann, T.1    Casademunt, E.2    Hollerbach, E.3    Hofmann, J.4    Dechant, G.5    Frotscher, M.6    Barde, Y.A.7
  • 49
    • 0035824391 scopus 로고    scopus 로고
    • gamma -Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase
    • Ni C.Y., Murphy M.P., Golde T.E., and Carpenter G. gamma -Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase. Science 294 (2001) 2179-2181
    • (2001) Science , vol.294 , pp. 2179-2181
    • Ni, C.Y.1    Murphy, M.P.2    Golde, T.E.3    Carpenter, G.4
  • 51
    • 0026058318 scopus 로고
    • Cell death during development of the nervous system
    • Oppenheim R.W. Cell death during development of the nervous system. Annu. Rev. Neurosci. 14 (1991) 453-501
    • (1991) Annu. Rev. Neurosci. , vol.14 , pp. 453-501
    • Oppenheim, R.W.1
  • 54
    • 0035933783 scopus 로고    scopus 로고
    • The p75 neurotrophin receptor activates Akt (protein kinase B) through a phosphatidylinositol 3-kinase-dependent pathway
    • Roux P.P., Bhakar A.L., Kennedy T.E., and Barker P.A. The p75 neurotrophin receptor activates Akt (protein kinase B) through a phosphatidylinositol 3-kinase-dependent pathway. J. Biol. Chem. 276 (2001) 23097-23104
    • (2001) J. Biol. Chem. , vol.276 , pp. 23097-23104
    • Roux, P.P.1    Bhakar, A.L.2    Kennedy, T.E.3    Barker, P.A.4
  • 55
    • 0033695190 scopus 로고    scopus 로고
    • NRAGE, a novel MAGE protein, interacts with the p75 neurotrophin receptor and facilitates nerve growth factor-dependent apoptosis
    • Salehi A.H., Roux P.P., Kubu C.J., Zeindler C., Bhakar A., Tannis L.L., Verdi J.M., and Barker P.A. NRAGE, a novel MAGE protein, interacts with the p75 neurotrophin receptor and facilitates nerve growth factor-dependent apoptosis. Neuron 27 (2000) 279-288
    • (2000) Neuron , vol.27 , pp. 279-288
    • Salehi, A.H.1    Roux, P.P.2    Kubu, C.J.3    Zeindler, C.4    Bhakar, A.5    Tannis, L.L.6    Verdi, J.M.7    Barker, P.A.8
  • 56
    • 2242447082 scopus 로고    scopus 로고
    • NRAGE, a p75 neurotrophin receptor-interacting protein, induces caspase activation and cell death through a JNK-dependent mitochondrial pathway
    • Salehi A.H., Xanthoudakis S., and Barker P.A. NRAGE, a p75 neurotrophin receptor-interacting protein, induces caspase activation and cell death through a JNK-dependent mitochondrial pathway. J. Biol. Chem. 277 (2002) 48043-48050
    • (2002) J. Biol. Chem. , vol.277 , pp. 48043-48050
    • Salehi, A.H.1    Xanthoudakis, S.2    Barker, P.A.3
  • 57
    • 1242265691 scopus 로고    scopus 로고
    • Notch signaling activity
    • Schweisguth F. Notch signaling activity. Curr. Biol. 14 (2004) R129-R138
    • (2004) Curr. Biol. , vol.14
    • Schweisguth, F.1
  • 59
    • 0041355557 scopus 로고    scopus 로고
    • Notch and Presenilin: regulated intramembrane proteolysis links development and degeneration
    • Selkoe D., and Kopan R. Notch and Presenilin: regulated intramembrane proteolysis links development and degeneration. Annu. Rev. Neurosci. 26 (2003) 565-597
    • (2003) Annu. Rev. Neurosci. , vol.26 , pp. 565-597
    • Selkoe, D.1    Kopan, R.2
  • 62
    • 0037072873 scopus 로고    scopus 로고
    • Mechanisms of p75-mediated death of hippocampal neurons. Role of caspases
    • Troy C.M., Friedman J.E., and Friedman W.J. Mechanisms of p75-mediated death of hippocampal neurons. Role of caspases. J. Biol. Chem. 277 (2002) 34295-34302
    • (2002) J. Biol. Chem. , vol.277 , pp. 34295-34302
    • Troy, C.M.1    Friedman, J.E.2    Friedman, W.J.3
  • 63
    • 0037038435 scopus 로고    scopus 로고
    • p75 interacts with the Nogo receptor as a co-receptor for Nogo, MAG and OMgp
    • Wang K.C., Kim J.A., Sivasankaran R., Segal R., and He Z. p75 interacts with the Nogo receptor as a co-receptor for Nogo, MAG and OMgp. Nature 420 (2002) 74-78
    • (2002) Nature , vol.420 , pp. 74-78
    • Wang, K.C.1    Kim, J.A.2    Sivasankaran, R.3    Segal, R.4    He, Z.5
  • 64
    • 1042278167 scopus 로고    scopus 로고
    • Evidence for a critical role of the tumor necrosis factor alpha convertase (TACE) in ectodomain shedding of the p75 neurotrophin receptor (p75NTR)
    • Weskamp G., Schlondorff J., Lum L., Becherer J.D., Kim T.W., Saftig P., Hartmann D., Murphy G., and Blobel C.P. Evidence for a critical role of the tumor necrosis factor alpha convertase (TACE) in ectodomain shedding of the p75 neurotrophin receptor (p75NTR). J. Biol. Chem. 279 (2004) 4241-4249
    • (2004) J. Biol. Chem. , vol.279 , pp. 4241-4249
    • Weskamp, G.1    Schlondorff, J.2    Lum, L.3    Becherer, J.D.4    Kim, T.W.5    Saftig, P.6    Hartmann, D.7    Murphy, G.8    Blobel, C.P.9
  • 65
    • 0036897583 scopus 로고    scopus 로고
    • A p75(NTR) and Nogo receptor complex mediates repulsive signaling by myelin-associated glycoprotein
    • Wong S.T., Henley J.R., Kanning K.C., Huang K.H., Bothwell M., and Poo M.M. A p75(NTR) and Nogo receptor complex mediates repulsive signaling by myelin-associated glycoprotein. Nat. Neurosci. 5 (2002) 1302-1308
    • (2002) Nat. Neurosci. , vol.5 , pp. 1302-1308
    • Wong, S.T.1    Henley, J.R.2    Kanning, K.C.3    Huang, K.H.4    Bothwell, M.5    Poo, M.M.6
  • 67
    • 0030610047 scopus 로고    scopus 로고
    • Absence of p75NTR causes increased basal forebrain cholinergic neuron size, choline acetyltransferase activity, and target innervation
    • Yeo T.T., Chua-Couzens J., Butcher L.L., Bredesen D.E., Cooper J.D., Valletta J.S., Mobley W.C., and Longo F.M. Absence of p75NTR causes increased basal forebrain cholinergic neuron size, choline acetyltransferase activity, and target innervation. J. Neurosci. 17 (1997) 7594-7605
    • (1997) J. Neurosci. , vol.17 , pp. 7594-7605
    • Yeo, T.T.1    Chua-Couzens, J.2    Butcher, L.L.3    Bredesen, D.E.4    Cooper, J.D.5    Valletta, J.S.6    Mobley, W.C.7    Longo, F.M.8
  • 68
    • 17644388524 scopus 로고    scopus 로고
    • Cleavage of p75 Neurotrophin receptor by α-secretase and γ-secretase requires specific domains
    • Zampieri N., Xu C.F., Neubert T.A., and Chao M.V. Cleavage of p75 Neurotrophin receptor by α-secretase and γ-secretase requires specific domains. J. Biol. Chem. 280 (2005) 14563-14571
    • (2005) J. Biol. Chem. , vol.280 , pp. 14563-14571
    • Zampieri, N.1    Xu, C.F.2    Neubert, T.A.3    Chao, M.V.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.