A model for neuronal competition during development

Science

Volumn 320, Issue 5874, 2008, Pages 369-373

  Deppmann, Christopher D ^a   Mihalas, Stefan ^a   Sharma, Nikhil ^a   Lonze, Bonnie E ^a   Niebur, Ernst ^a   Ginty, David D ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; KRUPPEL LIKE FACTOR; NERVE GROWTH FACTOR; NEUROTROPHIN 4; NEUROTROPHIN RECEPTOR P75; PROTEIN TYROSINE KINASE A; TYROSINE 3 MONOOXYGENASE;

COMPETITION (ECOLOGY); FEEDBACK MECHANISM; SIGNALING; SURVIVAL;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL SURVIVAL; COMPETITION; COMPUTER SIMULATION; CONTROLLED STUDY; FEEDBACK SYSTEM; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MATHEMATICAL MODEL; MICROARRAY ANALYSIS; MOUSE; NERVE CELL DIFFERENTIATION; NONHUMAN; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SYMPATHETIC NERVE CELL; WESTERN BLOTTING;

ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL SURVIVAL; CELLS, CULTURED; COMPUTER SIMULATION; FEEDBACK, BIOCHEMICAL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MATHEMATICS; MICE; MODELS, NEUROLOGICAL; NERVE GROWTH FACTOR; NERVE GROWTH FACTORS; NEURONS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RATS; RECEPTOR, TRKA; RECEPTORS, NERVE GROWTH FACTOR; SIGNAL TRANSDUCTION; SUPERIOR CERVICAL GANGLION;

RATTUS;

EID: 42349090693     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1152677     Document Type: Article

References (25)

1. V. Hamburger, R. Levi-Montalcini, J. Exp. Zool. 111, 457 (1949).
2. R. Levi-Montalcini, Science 237, 1154 (1987).
3. R. Levi-Montalcini, B. Booker, Proc. Natl. Acad. Sci. U.S.A. 46, 384 (1960).
4. C. Crowley et al., Cell 76, 1001 (1994).
5. H. M. Heerssen, M. F. Pazyra, R. A. Segal, Nat. Neurosci. 7, 596 (2004).
6. A. Riccio, S. Ahn, C. M. Davenport, J. A. Blendy, D. D. Ginty, Science 286, 2358 (1999).
7. F. L. Watson et al., Nat. Neurosci. 4, 981 (2001).
8. H. Ye, R. Kuruvilla, L. S. Zweifel, D. D. Ginty, Neuron 39, 57 (2003).
9. J. D. Delcroix et al., Neuron 39, 69 (2003).
10. C. L. Howe, W. C. Mobley, Curr. Opin. Neurobiol. 15, 40 (2005).
11. Materials and methods are available as supporting material on Science Online.
12. N. O. Glebova, D. D. Ginty, J. Neurosci. 24, 743 (2004).
13. T. D. Patel, A. Jackman, F. L. Rice, J. Kucera, W. D. Snider, Neuron 25, 345 (2000).
14. T. L. Deckwerth et al., Neuron 17, 401 (1996).
15. L. Lei, L. Ma, S. Nef, T. Thai, L. F. Parada, Development 128, 1147 (2001).
16. J. R. Sanes, J. W. Lichtman, Annu. Rev. Neurosci. 22, 389 (1999).
17. E. C. Yeiser, N. J. Rutkoski, A. Naito, J. Inoue, B. D. Carter, J. Neurosci. 24, 10521 (2004).
18. S. X. Bamji et al., J. Cell Biol. 140, 911 (1998).
19. M. Majdan, G. S. Walsh, R. Aloyz, F. D. Miller, J. Cell Biol. 155, 1275 (2001).
20. S. Wyatt, A. M. Davies, J. Cell Biol. 130, 1435 (1995).
21. R. Kuruvilla et al., Cell 118, 243 (2004).
22. F. D. Miller, T. C. Mathew, J. G. Toma, J. Cell Biol. 112, 303 (1991).
23. R. B. Campenot, Methods Enzymol. 58, 302 (1979).
24. C. Brennan, K. Rivas-Plata, S. C. Landis, Nat. Neurosci. 2, 699 (1999).
25. We thank C. Jie and F. Martinez Murillo of the Johns Hopkins Medical Institute microarray core for their assistance in microarray analysis; and N. Gaiano, A. Harrington, R. Kuruvilla, A. Levchenko, W. Luo, and K. Wright for helpful comments during manuscript preparation. This work is supported by NIH fellowship NS053187 (C.D.D.), A Woodrow Wilson Undergraduate Research Fellowship (N.S.), and NIH grants NS34814 (D.D.G.) and EY016281 (E.N.). D.D.G. is an investigator of the Howard Hughes Medical Institute. The microarray analysis data have been deposited in National Center for Biotechnology Information's Gene Expression Omnibus (GEO, www.ncbi.nlm.nih.gov/geo/), accession no. GSE10498.