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Volumn 25, Issue 9, 2014, Pages 893-902

Capsaicin-induced transcriptional changes in hypothalamus and alterations in gut microbial count in high fat diet fed mice

Author keywords

Anti obesity; Capsaicin; Gut microflora; Hypothalamus; TRPV1

Indexed keywords

ADIPONECTIN; CAPSAICIN; LEPTIN; GLUCOSE BLOOD LEVEL; PRIMER DNA;

EID: 84905224561     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2014.04.004     Document Type: Article
Times cited : (91)

References (58)
  • 1
    • 84905229367 scopus 로고    scopus 로고
    • World Health Statistics.
    • World Health Statistics 2012.
    • (2012)
  • 3
    • 79952084858 scopus 로고    scopus 로고
    • Dietary polyphenols and obesity
    • Meydani M., Hasan S.T. Dietary polyphenols and obesity. Nutrients 2010, 2(7):737-751.
    • (2010) Nutrients , vol.2 , Issue.7 , pp. 737-751
    • Meydani, M.1    Hasan, S.T.2
  • 4
    • 84876379831 scopus 로고    scopus 로고
    • Vegetables containing phytochemicals with potential anti-obesity properties: a review
    • Williams D.J., Edwards D., Hamernig I., Jian L., James A.P., Johnson S.K., et al. Vegetables containing phytochemicals with potential anti-obesity properties: a review. Food Res Int 2013, 52:323-333.
    • (2013) Food Res Int , vol.52 , pp. 323-333
    • Williams, D.J.1    Edwards, D.2    Hamernig, I.3    Jian, L.4    James, A.P.5    Johnson, S.K.6
  • 5
    • 84890125300 scopus 로고    scopus 로고
    • Mechanisms and clinical uses of capsaicin
    • Sharma S.K., Vij A.S., Sharma M. Mechanisms and clinical uses of capsaicin. Eur J Pharmacol 2013, 720(1-3):55-62.
    • (2013) Eur J Pharmacol , vol.720 , Issue.1-3 , pp. 55-62
    • Sharma, S.K.1    Vij, A.S.2    Sharma, M.3
  • 6
    • 77950493222 scopus 로고    scopus 로고
    • Capsaicinoids in the hottest pepper Bhut Jolokia and its antioxidant and anti inflammatory activities
    • Liu Y., Nair M.G. Capsaicinoids in the hottest pepper Bhut Jolokia and its antioxidant and anti inflammatory activities. Nat Prod Commun 2010, 5(1):91-94.
    • (2010) Nat Prod Commun , vol.5 , Issue.1 , pp. 91-94
    • Liu, Y.1    Nair, M.G.2
  • 7
    • 34247168128 scopus 로고    scopus 로고
    • Activation of transient receptor potential vanilloid type-1 channel prevents adipogenesis and obesity
    • Zhang L.L., Yan Liu D., Ma L.Q., Luo Z.D., Cao T.B., Zhong J., et al. Activation of transient receptor potential vanilloid type-1 channel prevents adipogenesis and obesity. Circ Res 2007, 100(7):1063-1070.
    • (2007) Circ Res , vol.100 , Issue.7 , pp. 1063-1070
    • Zhang, L.L.1    Yan Liu, D.2    Ma, L.Q.3    Luo, Z.D.4    Cao, T.B.5    Zhong, J.6
  • 8
    • 74349091894 scopus 로고    scopus 로고
    • Non-pungent capsaicin analogs (capsinoids) increase metabolic rate and enhance thermogenesis via gastrointestinal TRPV1 in mice
    • Kawabata F., Inoue N., Masamoto Y., Matsumura S., Kimura W., Kadowaki M., et al. Non-pungent capsaicin analogs (capsinoids) increase metabolic rate and enhance thermogenesis via gastrointestinal TRPV1 in mice. Biosci Biotechnol Biochem 2009, 73(12):2690-2697.
    • (2009) Biosci Biotechnol Biochem , vol.73 , Issue.12 , pp. 2690-2697
    • Kawabata, F.1    Inoue, N.2    Masamoto, Y.3    Matsumura, S.4    Kimura, W.5    Kadowaki, M.6
  • 9
    • 84857784321 scopus 로고    scopus 로고
    • TRPV1 activation improves exercise endurance and energy metabolism through PGC-1α upregulation in mice
    • Luo Z., Ma L., Zhao Z., He H., Yang D., Feng X., et al. TRPV1 activation improves exercise endurance and energy metabolism through PGC-1α upregulation in mice. Cell Res 2012, 22(3):551-564.
    • (2012) Cell Res , vol.22 , Issue.3 , pp. 551-564
    • Luo, Z.1    Ma, L.2    Zhao, Z.3    He, H.4    Yang, D.5    Feng, X.6
  • 10
    • 20044370154 scopus 로고    scopus 로고
    • Sensory and gastrointestinal satiety effects of capsaicin on food intake
    • Westerterp-Plantenga M.S., Smeets A., Lejeune M.P. Sensory and gastrointestinal satiety effects of capsaicin on food intake. Int J Obes (Lond) 2005, 299(6):682-688.
    • (2005) Int J Obes (Lond) , vol.299 , Issue.6 , pp. 682-688
    • Westerterp-Plantenga, M.S.1    Smeets, A.2    Lejeune, M.P.3
  • 11
    • 84891834540 scopus 로고    scopus 로고
    • Combined medium-chain triglyceride and chilli feeding increases diet-induced thermogenesis in normal weight humans
    • Clegg M.E., Golsorkhi M., Henry C.J. Combined medium-chain triglyceride and chilli feeding increases diet-induced thermogenesis in normal weight humans. Eur J Nutr 2012, 52(6):1579-1585.
    • (2012) Eur J Nutr , vol.52 , Issue.6 , pp. 1579-1585
    • Clegg, M.E.1    Golsorkhi, M.2    Henry, C.J.3
  • 12
    • 84855904085 scopus 로고    scopus 로고
    • The effects of capsaicin and capsiate on energy balance: critical review and meta-analyses of studies in humans
    • Ludy M.J., Moore G.E., Mattes R.D. The effects of capsaicin and capsiate on energy balance: critical review and meta-analyses of studies in humans. Chem Senses 2012, 37(2):103-121.
    • (2012) Chem Senses , vol.37 , Issue.2 , pp. 103-121
    • Ludy, M.J.1    Moore, G.E.2    Mattes, R.D.3
  • 13
    • 84879750170 scopus 로고    scopus 로고
    • Acute effects of capsaicin on energy expenditure and fat oxidation in negative energy balance
    • Janssens P.L.H.R., Hursel R., Martens E.A.P., Westerterp-Plantenga M.S. Acute effects of capsaicin on energy expenditure and fat oxidation in negative energy balance. PLoS One 2013, 8(7):e67786.
    • (2013) PLoS One , vol.8 , Issue.7
    • Janssens, P.L.H.R.1    Hursel, R.2    Martens, E.A.P.3    Westerterp-Plantenga, M.S.4
  • 14
    • 77950861528 scopus 로고    scopus 로고
    • Thermogenic ingredients and body weight regulation
    • Hursel R., Westerterp-Plantenga M.S. Thermogenic ingredients and body weight regulation. Int J Obes (Lond) 2010, 34(4):659-669.
    • (2010) Int J Obes (Lond) , vol.34 , Issue.4 , pp. 659-669
    • Hursel, R.1    Westerterp-Plantenga, M.S.2
  • 15
    • 84859046511 scopus 로고    scopus 로고
    • Nonpungent capsaicin analogs (capsinoids) increase energy expenditure through the activation of brown adipose tissue in humans
    • Yoneshiro T., Aita S., Kawai Y., Iwanaga T., Saito M. Nonpungent capsaicin analogs (capsinoids) increase energy expenditure through the activation of brown adipose tissue in humans. Am J Clin Nutr 2012, 95(4):845-850.
    • (2012) Am J Clin Nutr , vol.95 , Issue.4 , pp. 845-850
    • Yoneshiro, T.1    Aita, S.2    Kawai, Y.3    Iwanaga, T.4    Saito, M.5
  • 16
    • 84873131782 scopus 로고    scopus 로고
    • Hypothalamic control of energy balance: insights into the role of synaptic plasticity
    • Dietrich M.O., Horvath T.L. Hypothalamic control of energy balance: insights into the role of synaptic plasticity. Trends Neurosci 2013, 36(2):65-73.
    • (2013) Trends Neurosci , vol.36 , Issue.2 , pp. 65-73
    • Dietrich, M.O.1    Horvath, T.L.2
  • 17
    • 80052934802 scopus 로고    scopus 로고
    • The expression pattern of TRPV1 in brain
    • Menigoz A., Boudes M. The expression pattern of TRPV1 in brain. J Neurosci 2011, 31(37):13025-13027.
    • (2011) J Neurosci , vol.31 , Issue.37 , pp. 13025-13027
    • Menigoz, A.1    Boudes, M.2
  • 18
    • 80051680169 scopus 로고    scopus 로고
    • Preservation of acute pain and efferent functions following intrathecal resiniferatoxin-induced analgesia in rats
    • Bishnoi M., Bosgraaf C.A., Premkumar L.S. Preservation of acute pain and efferent functions following intrathecal resiniferatoxin-induced analgesia in rats. J Pain 2011, 12(9):991-1003.
    • (2011) J Pain , vol.12 , Issue.9 , pp. 991-1003
    • Bishnoi, M.1    Bosgraaf, C.A.2    Premkumar, L.S.3
  • 19
    • 79951683913 scopus 로고    scopus 로고
    • Obesity, diabetes and gut microbiota
    • Musso G., Gambino R., Cassader M. Obesity, diabetes and gut microbiota. Diabetes Care 2010, 33(10):2277-2284.
    • (2010) Diabetes Care , vol.33 , Issue.10 , pp. 2277-2284
    • Musso, G.1    Gambino, R.2    Cassader, M.3
  • 20
    • 84866546211 scopus 로고    scopus 로고
    • Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour
    • Cryan J.F., Dinan T.G. Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour. Nat Rev Neurosci 2012, 13(10):701-712.
    • (2012) Nat Rev Neurosci , vol.13 , Issue.10 , pp. 701-712
    • Cryan, J.F.1    Dinan, T.G.2
  • 21
    • 84878465280 scopus 로고    scopus 로고
    • Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity
    • Everard A., Belzer C., Geurts L., Ouwerkerk J.P., Druart C., Bindels L.B., et al. Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity. Proc Natl Acad Sci U S A 2013, 110(22):9066-9071.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , Issue.22 , pp. 9066-9071
    • Everard, A.1    Belzer, C.2    Geurts, L.3    Ouwerkerk, J.P.4    Druart, C.5    Bindels, L.B.6
  • 22
    • 84870374152 scopus 로고    scopus 로고
    • Diet induced dysbiosis of the intestinal microbiota and the effects on immunity and disease
    • Brown K., DeCoffe D., Molcan E., Gibson D.L. Diet induced dysbiosis of the intestinal microbiota and the effects on immunity and disease. Nutrients 2012, 4(8):1095-1119.
    • (2012) Nutrients , vol.4 , Issue.8 , pp. 1095-1119
    • Brown, K.1    DeCoffe, D.2    Molcan, E.3    Gibson, D.L.4
  • 23
    • 85027916882 scopus 로고    scopus 로고
    • Capsicum annuum enhances l-lactate production by Lactobacillus acidophilus: implication in curd formation
    • Sharma S., Jain S., Nair G.N., Ramachandran S. Capsicum annuum enhances l-lactate production by Lactobacillus acidophilus: implication in curd formation. J Dairy Sci 2013, 96(7):4142-4148.
    • (2013) J Dairy Sci , vol.96 , Issue.7 , pp. 4142-4148
    • Sharma, S.1    Jain, S.2    Nair, G.N.3    Ramachandran, S.4
  • 24
    • 84890128058 scopus 로고    scopus 로고
    • Verapamil augments the neuroprotectant action of berberine in rat model of transient global cerebral ischemia
    • Singh D.P., Chopra K. Verapamil augments the neuroprotectant action of berberine in rat model of transient global cerebral ischemia. Eur J Pharmacol 2013, 720(1-3):98-106.
    • (2013) Eur J Pharmacol , vol.720 , Issue.1-3 , pp. 98-106
    • Singh, D.P.1    Chopra, K.2
  • 25
    • 84886281122 scopus 로고    scopus 로고
    • Transient receptor potential channels and energy homeostasis
    • Ahern G.P. Transient receptor potential channels and energy homeostasis. Trends Endocrinol Metab 2013, 24(11):554-560.
    • (2013) Trends Endocrinol Metab , vol.24 , Issue.11 , pp. 554-560
    • Ahern, G.P.1
  • 26
    • 78650629113 scopus 로고    scopus 로고
    • The effects of hedonically acceptable red pepper doses on thermogenesis and appetite
    • Ludy M.J., Mattes R.D. The effects of hedonically acceptable red pepper doses on thermogenesis and appetite. Physiol Behav 2011, 102(3-4):251-258.
    • (2011) Physiol Behav , vol.102 , Issue.3-4 , pp. 251-258
    • Ludy, M.J.1    Mattes, R.D.2
  • 27
    • 79951991598 scopus 로고    scopus 로고
    • Dietary capsaicin attenuates metabolic dysregulation in genetically obese diabetic mice
    • Kang J.H., Tsuyoshi G., Le Ngoc H., Kim H.M., Tu T.H., Noh H.J., et al. Dietary capsaicin attenuates metabolic dysregulation in genetically obese diabetic mice. J Med Food 2011, 14(3):310-315.
    • (2011) J Med Food , vol.14 , Issue.3 , pp. 310-315
    • Kang, J.H.1    Tsuyoshi, G.2    Le Ngoc, H.3    Kim, H.M.4    Tu, T.H.5    Noh, H.J.6
  • 28
    • 84876294971 scopus 로고    scopus 로고
    • Topical application of capsaicin reduces visceral adipose fat by affecting adipokine levels in high-fat diet-induced obese mice
    • Lee G.R., Shin M.K., Yoon D.J., Kim A.R., Yu R., Park N.H., et al. Topical application of capsaicin reduces visceral adipose fat by affecting adipokine levels in high-fat diet-induced obese mice. Obesity (Silver Spring) 2013, 21(1):115-122.
    • (2013) Obesity (Silver Spring) , vol.21 , Issue.1 , pp. 115-122
    • Lee, G.R.1    Shin, M.K.2    Yoon, D.J.3    Kim, A.R.4    Yu, R.5    Park, N.H.6
  • 29
    • 77950187437 scopus 로고    scopus 로고
    • Dietary capsaicin reduces obesity-induced insulin resistance and hepatic steatosis in obese mice fed a high-fat diet
    • Kang J.-H., Tsuyoshi G., Han I.-S., Kawada T., Kim Y.M., Yu R. Dietary capsaicin reduces obesity-induced insulin resistance and hepatic steatosis in obese mice fed a high-fat diet. Obesity 2010, 18(4):780-787.
    • (2010) Obesity , vol.18 , Issue.4 , pp. 780-787
    • Kang, J.-H.1    Tsuyoshi, G.2    Han, I.-S.3    Kawada, T.4    Kim, Y.M.5    Yu, R.6
  • 30
    • 84869052722 scopus 로고    scopus 로고
    • Effect of caffeine and capsaicin on the blood glucose levels of obese/diabetic KK-A(y) mice
    • Okumura T., Tsukui T., Hosokawa M., Miyashita K. Effect of caffeine and capsaicin on the blood glucose levels of obese/diabetic KK-A(y) mice. J Oleo Sci 2012, 61(9):515-523.
    • (2012) J Oleo Sci , vol.61 , Issue.9 , pp. 515-523
    • Okumura, T.1    Tsukui, T.2    Hosokawa, M.3    Miyashita, K.4
  • 32
    • 34047214228 scopus 로고    scopus 로고
    • Review physiology, pharmacology, and therapeutic relevance of urocortins in mammals: ancient CRF paralogs
    • Fekete E.M., Zorrilla E.P. Review physiology, pharmacology, and therapeutic relevance of urocortins in mammals: ancient CRF paralogs. Front Neuroendocrinol 2007, 28(1):1-27.
    • (2007) Front Neuroendocrinol , vol.28 , Issue.1 , pp. 1-27
    • Fekete, E.M.1    Zorrilla, E.P.2
  • 33
    • 0035199423 scopus 로고    scopus 로고
    • Peripheral urocortin inhibits gastric emptying and food intake in mice: differential role of CRF receptor 2
    • Wang L., Martinez V., Rivier J.E., Tache Y. Peripheral urocortin inhibits gastric emptying and food intake in mice: differential role of CRF receptor 2. Am J Physiol Regul Integr Comp Physiol 2001, 281(5):R1401-R1410.
    • (2001) Am J Physiol Regul Integr Comp Physiol , vol.281 , Issue.5
    • Wang, L.1    Martinez, V.2    Rivier, J.E.3    Tache, Y.4
  • 34
    • 84873106561 scopus 로고    scopus 로고
    • BDNF and the central control of feeding: accidental bystander or essential player?
    • Rios M. BDNF and the central control of feeding: accidental bystander or essential player?. Trends Neurosci 2013, 36(2):83-90.
    • (2013) Trends Neurosci , vol.36 , Issue.2 , pp. 83-90
    • Rios, M.1
  • 35
    • 84859560308 scopus 로고    scopus 로고
    • Dendritically targeted Bdnf mRNA is essential for energy balance and response to leptin
    • Liao G.Y., An J.J., Gharami K., Waterhouse E.G., Vanevski F., Jones K.R., et al. Dendritically targeted Bdnf mRNA is essential for energy balance and response to leptin. Nat Med 2012, 18(4):564-571.
    • (2012) Nat Med , vol.18 , Issue.4 , pp. 564-571
    • Liao, G.Y.1    An, J.J.2    Gharami, K.3    Waterhouse, E.G.4    Vanevski, F.5    Jones, K.R.6
  • 36
    • 80052739107 scopus 로고    scopus 로고
    • White to brown fat phenotypic switch induced by genetic and environmental activation of a hypothalamic-adipocyte axis
    • Cao L., Choi E.Y., Liu X., Martin A., Wang C., Xu X., et al. White to brown fat phenotypic switch induced by genetic and environmental activation of a hypothalamic-adipocyte axis. Cell Metab 2011, 14(3):324-338.
    • (2011) Cell Metab , vol.14 , Issue.3 , pp. 324-338
    • Cao, L.1    Choi, E.Y.2    Liu, X.3    Martin, A.4    Wang, C.5    Xu, X.6
  • 37
    • 2442707521 scopus 로고    scopus 로고
    • Expressional changes of neuropeptide Y and cholecystokinin in the arcuate and paraventricular nuclei after capsaicin administration
    • Lee I.S., Nam Y.S., Lee C.H., Chung D.W., Yoon Y.S., Kim J.S., et al. Expressional changes of neuropeptide Y and cholecystokinin in the arcuate and paraventricular nuclei after capsaicin administration. J Nutr Sci Vitaminol (Tokyo) 2004, 50(2):144-148.
    • (2004) J Nutr Sci Vitaminol (Tokyo) , vol.50 , Issue.2 , pp. 144-148
    • Lee, I.S.1    Nam, Y.S.2    Lee, C.H.3    Chung, D.W.4    Yoon, Y.S.5    Kim, J.S.6
  • 38
    • 79954620647 scopus 로고    scopus 로고
    • Intragastric administration of capsiate, a transient receptor potential channel agonist, triggers thermogenic sympathetic responses
    • Ono K., Tsukamoto-Yasui M., Hara-Kimura Y., Inoue N., Nogusa Y., Okabe Y., et al. Intragastric administration of capsiate, a transient receptor potential channel agonist, triggers thermogenic sympathetic responses. J Appl Physiol 2011, 110(3):789-798.
    • (2011) J Appl Physiol , vol.110 , Issue.3 , pp. 789-798
    • Ono, K.1    Tsukamoto-Yasui, M.2    Hara-Kimura, Y.3    Inoue, N.4    Nogusa, Y.5    Okabe, Y.6
  • 40
  • 41
    • 84886404045 scopus 로고    scopus 로고
    • Transient receptor potential activated brown fat thermogenesis as a target of food ingredients for obesity management
    • Yoneshiro T., Saito M. Transient receptor potential activated brown fat thermogenesis as a target of food ingredients for obesity management. Curr Opin Clin Nutr Metab Care 2013, 16(6):625-631.
    • (2013) Curr Opin Clin Nutr Metab Care , vol.16 , Issue.6 , pp. 625-631
    • Yoneshiro, T.1    Saito, M.2
  • 42
    • 84881221754 scopus 로고    scopus 로고
    • Recruited brown adipose tissue as an anti-obesity agent in humans
    • Yoneshiro T., Aita S., Matsushita M., Kayahara T., Kameya T., et al. Recruited brown adipose tissue as an anti-obesity agent in humans. J Clin Investig 2013, 123(8):3404-3408.
    • (2013) J Clin Investig , vol.123 , Issue.8 , pp. 3404-3408
    • Yoneshiro, T.1    Aita, S.2    Matsushita, M.3    Kayahara, T.4    Kameya, T.5
  • 43
    • 84872857675 scopus 로고    scopus 로고
    • Capsinoids and related food ingredients activating brown fat thermogenesis and reducing body fat in humans
    • Saito M., Yoneshiro T. Capsinoids and related food ingredients activating brown fat thermogenesis and reducing body fat in humans. Curr Opin Lipidol 2013, 24(1):71-77.
    • (2013) Curr Opin Lipidol , vol.24 , Issue.1 , pp. 71-77
    • Saito, M.1    Yoneshiro, T.2
  • 44
    • 84869882221 scopus 로고    scopus 로고
    • Manipulating molecular switches in brown adipocytes and their precursors: a therapeutic potential
    • Birerdinc A., Jarrar M., Stotish T., Randhawa M., Baranova A. Manipulating molecular switches in brown adipocytes and their precursors: a therapeutic potential. Prog Lipid Res 2013, 52(1):51-61.
    • (2013) Prog Lipid Res , vol.52 , Issue.1 , pp. 51-61
    • Birerdinc, A.1    Jarrar, M.2    Stotish, T.3    Randhawa, M.4    Baranova, A.5
  • 45
    • 79957793687 scopus 로고    scopus 로고
    • TRPV1 agonist monoacylglycerol increases UCP1 content in brown adipose tissue and suppresses accumulation of visceral fat in mice fed a high-fat and high-sucrose diet
    • Iwasaki Y., Tamura Y., Inayoshi K., Narukawa M., Kobata K., Chiba H., et al. TRPV1 agonist monoacylglycerol increases UCP1 content in brown adipose tissue and suppresses accumulation of visceral fat in mice fed a high-fat and high-sucrose diet. Biosci Biotechnol Biochem 2011, 75(5):904-909.
    • (2011) Biosci Biotechnol Biochem , vol.75 , Issue.5 , pp. 904-909
    • Iwasaki, Y.1    Tamura, Y.2    Inayoshi, K.3    Narukawa, M.4    Kobata, K.5    Chiba, H.6
  • 46
    • 78650945931 scopus 로고    scopus 로고
    • Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice
    • Seale P., Conroe H.M., Estall J., Kajimura S., Frontini A., Ishibashi J., et al. Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice. J Clin Invest 2011, 121(1):96-105.
    • (2011) J Clin Invest , vol.121 , Issue.1 , pp. 96-105
    • Seale, P.1    Conroe, H.M.2    Estall, J.3    Kajimura, S.4    Frontini, A.5    Ishibashi, J.6
  • 47
    • 84894132767 scopus 로고    scopus 로고
    • A new era in brown adipose tissue biology: molecular control of brown fat development and energy homeostasis
    • Kajimura S., Saito M. A new era in brown adipose tissue biology: molecular control of brown fat development and energy homeostasis. Annu Rev Physiol 2014, 76:225-249.
    • (2014) Annu Rev Physiol , vol.76 , pp. 225-249
    • Kajimura, S.1    Saito, M.2
  • 48
    • 80052225187 scopus 로고    scopus 로고
    • Modulation of the gut microbiota by nutrients with prebiotic properties: consequences for host health in the context of obesity and metabolic syndrome
    • Delzenne N.M., Neyrinck A.M., Cani P.D. Modulation of the gut microbiota by nutrients with prebiotic properties: consequences for host health in the context of obesity and metabolic syndrome. Microb Cell Fact 2011, 10(Suppl. 1):S10.
    • (2011) Microb Cell Fact , vol.10 , Issue.SUPPL. 1
    • Delzenne, N.M.1    Neyrinck, A.M.2    Cani, P.D.3
  • 49
    • 33845901507 scopus 로고    scopus 로고
    • Microbial ecology: human gut microbes associated with obesity
    • Ley R.E., Turnbaugh P.J., Klein S., Gordon J.I. Microbial ecology: human gut microbes associated with obesity. Nature 2006, 444(7122):1022-1023.
    • (2006) Nature , vol.444 , Issue.7122 , pp. 1022-1023
    • Ley, R.E.1    Turnbaugh, P.J.2    Klein, S.3    Gordon, J.I.4
  • 51
    • 79151484704 scopus 로고    scopus 로고
    • Adipokines in inflammation and metabolic disease
    • Ouchi N., Parker J.L., Lugus J.J., Walsh K. Adipokines in inflammation and metabolic disease. Nat Rev Immunol 2011, 11(2):85-97.
    • (2011) Nat Rev Immunol , vol.11 , Issue.2 , pp. 85-97
    • Ouchi, N.1    Parker, J.L.2    Lugus, J.J.3    Walsh, K.4
  • 52
    • 77954672686 scopus 로고    scopus 로고
    • Gut microbiota composition is associated with body weight, weight gain and biochemical parameters in pregnant women
    • Santacruz A., Collado M.C., García-Valdés L., Segura M.T., Martín-Lagos J.A., Anjos T., et al. Gut microbiota composition is associated with body weight, weight gain and biochemical parameters in pregnant women. Br J Nutr 2010, 104(1):83-92.
    • (2010) Br J Nutr , vol.104 , Issue.1 , pp. 83-92
    • Santacruz, A.1    Collado, M.C.2    García-Valdés, L.3    Segura, M.T.4    Martín-Lagos, J.A.5    Anjos, T.6
  • 53
    • 84866386969 scopus 로고    scopus 로고
    • Early life treatment with vancomycin propagates Akkermansia muciniphila and reduces diabetes incidence in the NOD mouse
    • Hansen C.H., Krych L., Nielsen D.S., Vogensen F.K., Hansen L.H., Sørensen S.J., et al. Early life treatment with vancomycin propagates Akkermansia muciniphila and reduces diabetes incidence in the NOD mouse. Diabetologia 2012, 55(8):2285-2294.
    • (2012) Diabetologia , vol.55 , Issue.8 , pp. 2285-2294
    • Hansen, C.H.1    Krych, L.2    Nielsen, D.S.3    Vogensen, F.K.4    Hansen, L.H.5    Sørensen, S.J.6
  • 54
    • 5444248493 scopus 로고    scopus 로고
    • Akkermansia muciniphila gen. nov., sp. nov., a human intestinal mucin-degrading bacterium
    • Derrien M., Vaughan E.E., Plugge C.M., de Vos W.M. Akkermansia muciniphila gen. nov., sp. nov., a human intestinal mucin-degrading bacterium. Int J Syst Evol Microbiol 2004, 54(Pt 5):1469-1476.
    • (2004) Int J Syst Evol Microbiol , vol.54 , Issue.PART 5 , pp. 1469-1476
    • Derrien, M.1    Vaughan, E.E.2    Plugge, C.M.3    de Vos, W.M.4
  • 55
    • 80755152887 scopus 로고    scopus 로고
    • Responses of gut microbiota and glucose and lipid metabolism to prebiotics in genetic obese and diet-induced leptin-resistant mice
    • Everard A., Lazarevic V., Derrien M., Girard M., Muccioli G.G., Neyrinck A.M., et al. Responses of gut microbiota and glucose and lipid metabolism to prebiotics in genetic obese and diet-induced leptin-resistant mice. Diabetes 2011, 60(11):2775-2786.
    • (2011) Diabetes , vol.60 , Issue.11 , pp. 2775-2786
    • Everard, A.1    Lazarevic, V.2    Derrien, M.3    Girard, M.4    Muccioli, G.G.5    Neyrinck, A.M.6
  • 56
    • 84897960120 scopus 로고    scopus 로고
    • An increase in the Akkermansia spp. population induced by metformin treatment improves glucose homeostasis in diet-induced obese mice
    • Shin N.R., Lee J.C., Lee H.Y., Kim M.S., Whon T.W., Lee M.S., et al. An increase in the Akkermansia spp. population induced by metformin treatment improves glucose homeostasis in diet-induced obese mice. Gut 2014, 63(5):727-735.
    • (2014) Gut , vol.63 , Issue.5 , pp. 727-735
    • Shin, N.R.1    Lee, J.C.2    Lee, H.Y.3    Kim, M.S.4    Whon, T.W.5    Lee, M.S.6
  • 57
    • 84880511198 scopus 로고    scopus 로고
    • Functional food ingredients for the management of obesity and associated co-morbidities - a review
    • Baboota R.K., Bishnoi M., Ambalam P., Kondepudi K.K., Sarma S.M., Boparai R.K., et al. Functional food ingredients for the management of obesity and associated co-morbidities - a review. J Funct Foods 2013, 5(3):997-1012.
    • (2013) J Funct Foods , vol.5 , Issue.3 , pp. 997-1012
    • Baboota, R.K.1    Bishnoi, M.2    Ambalam, P.3    Kondepudi, K.K.4    Sarma, S.M.5    Boparai, R.K.6
  • 58
    • 84867616398 scopus 로고    scopus 로고
    • High fat diet-induced gut microbiota exacerbates inflammation and obesity in mice via the TLR4 signaling pathway
    • Kim K.-A., Gu W., Lee I.-A., Joh E.-H., Kim D.-H. High fat diet-induced gut microbiota exacerbates inflammation and obesity in mice via the TLR4 signaling pathway. PLoS One 2012, 7(10):e47713.
    • (2012) PLoS One , vol.7 , Issue.10
    • Kim, K.-A.1    Gu, W.2    Lee, I.-A.3    Joh, E.-H.4    Kim, D.-H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.