Activation and dynamic network of the M2 muscarinic receptor

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 27, 2013, Pages 10982-10987

  Miao, Yinglong ^a   Nichols, Sara E ^a   Gasper, Paul M ^a   Metzger, Vincent T ^a   McCammon, J Andrew ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Allosteric network; Cross correlations; Drug design; Enhanced sampling; GPCR signaling

Indexed keywords

HYDROGEN; MUSCARINIC M2 RECEPTOR;

ALPHA HELIX; ARTICLE; CRYSTAL STRUCTURE; HYDROGEN BOND; LIGAND BINDING; MOLECULAR DYNAMICS; PRIORITY JOURNAL; TILTING;

ALLOSTERIC NETWORK; CROSS-CORRELATIONS; DRUG DESIGN; ENHANCED SAMPLING; GPCR SIGNALING;

BINDING SITES; HUMANS; HYDROGEN BONDING; LIGANDS; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; PROTEIN CONFORMATION; PROTEIN INTERACTION DOMAINS AND MOTIFS; RECEPTOR, MUSCARINIC M2;

EID: 84879707465     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1309755110     Document Type: Article

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