Identification of an allosteric binding site for Zn2+ on the β2 adrenergic receptor

Journal of Biological Chemistry

Volumn 278, Issue 1, 2003, Pages 352-356

  Swaminath, Gayathri ^a   Lee, Tae Weon ^a   Kobilka, Brian ^a,b  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; DRUG DOSAGE; MUTAGENESIS; PROTEINS; ZINC;

LIGANDS;

BIOCHEMICAL ENGINEERING;

BETA 2 ADRENERGIC RECEPTOR; CYSTEINE; GLUTAMIC ACID; HISTIDINE; ZINC ION;

AGONIST; ALLOSTERISM; ANIMAL CELL; ARTICLE; BINDING SITE; CONTROLLED STUDY; HUMAN; HUMAN CELL; MUTATION; NONHUMAN; PRIORITY JOURNAL; RECEPTOR AFFINITY; RECEPTOR BINDING;

ADRENERGIC BETA-AGONISTS; ADRENERGIC BETA-ANTAGONISTS; ALLOSTERIC SITE; AMINO ACID SEQUENCE; BINDING SITES; CELL LINE; CYCLIC AMP; HUMANS; ISOPROTERENOL; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN STRUCTURE, SECONDARY; RADIOLIGAND ASSAY; RECEPTORS, ADRENERGIC, BETA-2; ZINC;

ANIMALIA;

EID: 0037414774     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M206424200     Document Type: Article

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