The intake of a hazelnut skin extract improves the plasma lipid profile and reduces the lithocholic/deoxycholic bile acid faecal ratio, a risk factor for colon cancer, in hamsters fed a high-fat diet

Food Chemistry

Volumn 167, Issue , 2015, Pages 138-144

  Caimari, Antoni ^a   Puiggròs, Francesc ^a   Suárez, Manuel ^b   Crescenti, Anna ^a   Laos, Sirle ^a   Ruiz, Juan Antonio ^c   Alonso, Virginia ^c   Moragas, Josep ^c   Del Bas, Josep Maria ^a   Arola, Lluís ^a,b  

^a Avinguda Universitat   (Spain)

^b UNIVERSITAT ROVIRA I VIRGILI   (Spain)

^c Unió Coorporació Alimentària Joan Oliver ^*  (Spain)

Author keywords

Bile acids; Blood cholesterol; Cardiovascular health; Colon metabolism; Hazelnut skin extract; Plasma lipid profile

Indexed keywords

BODY FLUIDS; CHOLESTEROL; FIBERS; METABOLISM; NUTRITION; PHYSIOLOGY;

BILE ACID; BLOOD CHOLESTEROL; CARDIO-VASCULAR DISEASE; CHOLESTEROL-LOWERING EFFECTS; DIFFERENT RISK FACTORS; HAZELNUT SKIN EXTRACT; PLASMA CHOLESTEROL; PLASMA LIPID;

DISEASES;

ANTILIPEMIC AGENT; ANTINEOPLASTIC AGENT; CHOLESTEROL; DEOXYCHOLIC ACID; FATTY ACID; FIBEROX; HAZELNUT SKIN EXTRACT; LITHOCHOLIC ACID; LOW DENSITY LIPOPROTEIN; PHOSPHOLIPID; PLANT EXTRACT; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; BILE ACID; LIPID;

ANIMAL EXPERIMENT; ARTICLE; BIOLOGICAL ACTIVITY; CANCER PREVENTION; CANCER RISK; CHOLESTEROL BLOOD LEVEL; COLON CANCER; CONTROLLED STUDY; DIETARY FIBER; FAT INTAKE; FECES ANALYSIS; FOOD INTAKE; GLUCOSE METABOLISM; HAZELNUT; HEMATOLOGICAL PARAMETERS; LIPID BLOOD LEVEL; LIPID DIET; MALE; METABOLIC SYNDROME X; NONHUMAN; RISK ASSESSMENT; RISK FACTOR; SYRIAN HAMSTER; ADVERSE EFFECTS; ANIMAL; BLOOD; CHEMISTRY; COLON TUMOR; HAMSTER; MESOCRICETUS;

ANIMALS; BILE ACIDS AND SALTS; COLONIC NEOPLASMS; CORYLUS; CRICETINAE; DEOXYCHOLIC ACID; DIET, HIGH-FAT; LIPIDS; LITHOCHOLIC ACID; MALE; MESOCRICETUS; RISK FACTORS;

EID: 84904321120     PISSN: 03088146     EISSN: 18737072     Source Type: Journal    
DOI: 10.1016/j.foodchem.2014.06.072     Document Type: Article

References (35)

1. C. Alasalvar, F. Shahidi, and K.R. Cadwallader Comparison of natural and roasted Turkish tombul hazelnut (Corylus avellana L.) volatiles and flavor by DHA/GC/MS and descriptive sensory analysis Journal of Agricultural and Food Chemistry 51 17 2003 5067 5072
2. C. Alasalvar, F. Shahidi, T. Ohshima, U. Wanasundara, H.C. Yurttas, and C.M. Liyanapathirana et al. Turkish Tombul hazelnut (Corylus avellana L.). 2. Lipid characteristics and oxidative stability Journal of Agricultural and Food Chemistry 51 13 2003 3797 3805
3. Association of Analytical Communities. (2000). Official methods of analysis of AOAC International. (17th ed.). Gaithersburg, MD, USA.
4. C. Bladé, L. Arola, and M.-J. Salvadó Hypolipidemic effects of proanthocyanidins and their underlying biochemical and molecular mechanisms Molecular Nutrition & Food Research 54 1 2010 37 59
5. A. Caimari, J.M. del Bas, A. Crescenti, and L. Arola Low doses of grape seed procyanidins reduce adiposity and improve the plasma lipid profile in hamsters International Journal of Obesity 37 4 2013 576 583
6. P. Casas-Agustench, P. López-Uriarte, M. Bulló, E. Ros, J.J. Cabré-Vila, and J. Salas-Salvadó Effects of one serving of mixed nuts on serum lipids, insulin resistance and inflammatory markers in patients with the metabolic syndrome Nutrition, Metabolism, and Cardiovascular Diseases: NMCD 21 2 2011 126 135
7. C.-F. Chau, and Y.-L. Huang Effects of the insoluble fiber derived from Passiflora edulis seed on plasma and hepatic lipids and fecal output Molecular Nutrition & Food Research 49 8 2005 786 790 (Pubitemid 41188587)
8. B.P. Daggy, N.C. O'Connell, G.R. Jerdack, B.a Stinson, and K.D. Setchell Additive hypocholesterolemic effect of psyllium and cholestyramine in the hamster: influence on fecal sterol and bile acid profiles Journal of Lipid Research 38 3 1997 491 502 (Pubitemid 27166692)
9. E. De Smet, R.P. Mensink, and J. Plat Effects of plant sterols and stanols on intestinal cholesterol metabolism: suggested mechanisms from past to present Molecular Nutrition & Food Research 56 7 2012 1058 1072
10. P.R. Debruyne, E.a. Bruyneel, X. Li, A. Zimber, C. Gespach, and M.M. Mareel The role of bile acids in carcinogenesis Mutation Research 480-481 2001 359 369 (Pubitemid 32744842)
11. D. Del Rio, L. Calani, M. Dall'Asta, and F. Brighenti Polyphenolic composition of hazelnut skin Journal of Agricultural and Food Chemistry 59 18 2011 9935 9941
12. M. Galisteo, R. Morón, L. Rivera, R. Romero, A. Anguera, and A. Zarzuelo Plantago ovata husks-supplemented diet ameliorates metabolic alterations in obese Zucker rats through activation of AMP-activated protein kinase. Comparative study with other dietary fibers Clinical Nutrition (Edinburgh, Scotland) 29 2 2010 261 267
13. M. Hagio, M. Matsumoto, and S. Ishizuka Bile acid analysis in various biological samples using ultra performance liquid chromatography/electrospray ionization-mass spectrometry (UPLC/ESI-MS) Methods in Molecular Biology 708 2011 119 129
14. Y.-J. Hong, M. Turowski, J.-T. Lin, and W.H. Yokoyama Simultaneous characterization of bile acid, sterols, and determination of acylglycerides in feces from soluble cellulose-fed hamsters using HPLC with evaporative light-scattering detection and APCI-MS Journal of Agricultural and Food Chemistry 55 24 2007 9750 9757 (Pubitemid 350305155)
15. Huguet, F.; Moragas, J.; Ruiz, J.A.; & Alonso, V. (2011). Fibra alimentaria antioxidante y procedimiento para su obtención. Unió Corporació Alimentària, SCCL. Spanish Patent ES 2.366.221. Submission date: 07.06.2011.
16. J.R. Lupton, G. Steinbach, W.C. Chang, B.C. O'Brien, S. Wiese, and C.L. Stoltzfus et al. Calcium supplementation modifies the relative amounts of bile acids in bile and affects key aspects of human colon physiology Journal of Nutrition 126 5 1996 1421 1428 (Pubitemid 26137701)
17. E. Lecumberri, L. Goya, R. Mateos, M. Alía, S. Ramos, and M. Izquierdo-Pulido et al. A diet rich in dietary fiber from cocoa improves lipid profile and reduces malondialdehyde in hypercholesterolemic rats Nutrition (Burbank, Los Angeles County, Calif.) 23 4 2007 332 341 (Pubitemid 46497648)
18. G. Mandalari, A. Tomaino, T. Arcoraci, M. Martorana, V.Lo Turco, and F. Cacciola et al. Characterization of polyphenols, lipids and dietary fibre from almond skins (Amygdalus communis L.) Journal of Food Composition and Analysis 23 2 2010 166 174
19. R. Montella, J.D. Coïsson, F. Travaglia, M. Locatelli, P. Malfa, and A. Martelli et al. Bioactive compounds from hazelnut skin (Corylus avellana L.): effects on Lactobacillus plantarum P17630 and Lactobacillus crispatus P17631 Journal of Functional Foods 5 1 2013 306 315
20. Y. Okazaki, Z. Utama, S. Suidasari, P. Zhang, N. Yanaka, and H. Tomotake et al. Consumption of vitamin B(6) reduces fecal ratio of lithocholic acid to deoxycholic acid, a risk factor for colon cancer, in rats fed a high-fat diet Journal of Nutritional Science and Vitaminology 58 5 2012 366 370
21. A. Orem, F.B. Yucesan, C. Orem, B. Akcan, B.V. Kural, and C. Alasalvar et al. Hazelnut-enriched diet improves cardiovascular risk biomarkers beyond a lipid-lowering effect in hypercholesterolemic subjects Journal of Clinical Lipidology 7 2 2013 123 131
22. R.W. Owen, D.W. Day, and M.H. Thompson Faecal steroids and colorectal cancer: steroid profiles in subjects with adenomatous polyps of the large bowel European Journal of Cancer Prevention: The official Journal of the European Cancer Prevention Organisation (ECP) 1 2 1992 105 112
23. R.W. Owen, P.J. Henly, M.H. Thompson, and M.J. Hill Steroids and cancer: faecal bile acid screening for early detection of cancer risk Journal of Steroid Biochemistry 24 1 1986 391 394 (Pubitemid 16047812)
24. R.L. Prior, H. Hoang, L. Gu, X. Wu, M. Bacchiocca, and L. Howard et al. Assays for hydrophilic and lipophilic antioxidant capacity (oxygen radical absorbance capacity (ORAC(FL))) of plasma and other biological and food samples Journal of Agricultural and Food Chemistry 51 11 2003 3273 3279
25. Z. Qiang, S.-O. Lee, Z. Ye, X. Wu, and S. Hendrich Artichoke extract lowered plasma cholesterol and increased fecal bile acids in Golden Syrian hamsters Phytotherapy Research: PTR 26 7 2012 1048 1052
26. M. Quiñones, M. Miguel, and A. Aleixandre Beneficial effects of polyphenols on cardiovascular disease Pharmacological Research: The Official Journal of the Italian Pharmacological Society 68 1 2013 125 131
27. C.K. Roberts, A.L. Hevener, and R.J. Barnard Metabolic syndrome and insulin resistance. underlying causes and modification by exercise training Comprehensive Physiology 3 1 2013 1 58
28. E. Ros Nuts and novel biomarkers of cardiovascular disease The American journal of clinical nutrition 89 5 2009 1649S 1656S
29. D. Sánchez, L. Moulay, B. Muguerza, M. Quiñones, M. Miguel, and A. Aleixandre Effect of a soluble cocoa fiber-enriched diet in Zucker fatty rats Journal of Medicinal Food 13 3 2010 621 628
30. D. Sánchez, M. Quiñones, L. Moulay, B. Muguerza, M. Miguel, and A. Aleixandre Soluble fiber-enriched diets improve inflammation and oxidative stress biomarkers in Zucker fatty rats Pharmacological Research: The Official Journal of the Italian Pharmacological Society 64 1 2011 31 35
31. J. Slavin Fiber and prebiotics: mechanisms and health benefits Nutrients 5 4 2013 1417 1435
32. S.L. Tey, R.C. Brown, A.W. Chisholm, C.M. Delahunty, A.R. Gray, and S.M. Williams Effects of different forms of hazelnuts on blood lipids and α-tocopherol concentrations in mildly hypercholesterolemic individuals European Journal of Clinical Nutrition 65 1 2011 117 124
33. F.B. Yücesan, A. Orem, B.V. Kural, C. Orem, and I. Turan Hazelnut consumption decreases the susceptibility of LDL to oxidation, plasma oxidized LDL level and increases the ratio of large/small LDL in normolipidemic healthy subjects Anadolu Kardiyoloji Dergisi: AKD = the Anatolian Journal of Cardiology 10 1 2010 28 35
34. L. Zhang, M. Zhou, G. Fang, Y. Tang, Z. Chen, and X. Liu Hypocholesterolemic effect of capsaicinoids by increased bile acids excretion in ovariectomized rats Molecular Nutrition & Food Research 57 6 2013 1080 1088
35. E. Zuccato, M. Venturi, G. Di Leo, L. Colombo, C. Bertolo, and S.B. Doldi et al. Role of bile acids and metabolic activity of colonic bacteria in increased risk of colon cancer after cholecystectomy Digestive Diseases and Sciences 38 3 1993 514 519 (Pubitemid 23087128)