Differential regulation of Gli proteins by Sufu in the lung affects PDGF signaling and myofibroblast development

Developmental Biology

Volumn 392, Issue 2, 2014, Pages 324-333

  Lin, Chuwen ^a   Chen, Miao Hsueh ^a,b   Yao, Erica ^a   Song, Hai ^a   Gacayan, Rhodora ^a   Hui, Chi chung ^c   Chuang, Pao Tien ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

Gli; Hedgehog; Lung; Myofibroblast; PDGF; Sufu

Indexed keywords

CELL PROTEIN; NUMB PROTEIN; PLATELET DERIVED GROWTH FACTOR; REGULATOR PROTEIN; SONIC HEDGEHOG PROTEIN; SPOP PROTEIN; SUFU PROTEIN; TRANSCRIPTION FACTOR GLI1; TRANSCRIPTION FACTOR GLI2; TRANSCRIPTION FACTOR GLI3; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING SITE; CELL MATURATION; CHROMATIN IMMUNOPRECIPITATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; EMBRYO; GENE; GENE ACTIVATION; GENE LOSS; GENE TARGETING; LUCIFERASE ASSAY; LUNG; LUNG ALVEOLUS; MOUSE; MYOFIBROBLAST; NONHUMAN; PDGFRA GENE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEGRADATION; PROTEIN FUNCTION; PTCH1 GENE; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SUFU GENE; UPREGULATION; VALIDATION PROCESS;

GLI; HEDGEHOG; LUNG; MYOFIBROBLAST; PDGF; SUFU;

ANIMALS; BLOTTING, WESTERN; CHROMATIN IMMUNOPRECIPITATION; DNA PRIMERS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEDGEHOG PROTEINS; HEK293 CELLS; HISTOLOGICAL TECHNIQUES; HUMANS; IMMUNOPRECIPITATION; IN SITU HYBRIDIZATION; KRUPPEL-LIKE TRANSCRIPTION FACTORS; LUCIFERASES; LUNG; MICE; MICE, KNOCKOUT; MICROSCOPY, FLUORESCENCE; MODELS, BIOLOGICAL; MYOFIBROBLASTS; PLATELET-DERIVED GROWTH FACTOR; POLYMERASE CHAIN REACTION; REPRESSOR PROTEINS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 84904290230     PISSN: 00121606     EISSN: 1095564X     Source Type: Journal    
DOI: 10.1016/j.ydbio.2014.05.014     Document Type: Article

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