메뉴 건너뛰기




Volumn 379, Issue 2, 2013, Pages 221-228

Mouse limbs expressing only the Gli3 repressor resemble those of Sonic hedgehog mutants

Author keywords

Gli3; Hedgehog; Limb patterning

Indexed keywords

CRE RECOMBINASE; MUTANT PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI3; GLI3 PROTEIN, MOUSE; INTEGRASE; KRUPPEL LIKE FACTOR; NERVE PROTEIN; PRIMER DNA;

EID: 84878840427     PISSN: 00121606     EISSN: 1095564X     Source Type: Journal    
DOI: 10.1016/j.ydbio.2013.04.025     Document Type: Article
Times cited : (23)

References (38)
  • 2
    • 0030680207 scopus 로고    scopus 로고
    • Strike three for GLI3
    • Biesecker L.G. Strike three for GLI3. Nat. Genet. 1997, 17:259-260.
    • (1997) Nat. Genet. , vol.17 , pp. 259-260
    • Biesecker, L.G.1
  • 3
    • 0036566575 scopus 로고    scopus 로고
    • Pallister-hall syndrome phenotype in mice mutant for Gli3
    • Bose J., Grotewold L., Ruther U. Pallister-hall syndrome phenotype in mice mutant for Gli3. Hum. Mol. Genet. 2002, 11:1129-1135.
    • (2002) Hum. Mol. Genet. , vol.11 , pp. 1129-1135
    • Bose, J.1    Grotewold, L.2    Ruther, U.3
  • 4
    • 84865658146 scopus 로고    scopus 로고
    • Limb anterior-posterior polarity integrates activator and repressor functions of GLI2 as well as GLI3
    • Bowers, M., Eng, L., Lao, Z., Turnbull, R.K., Bao, X., Riedel, E., Mackem, S., Joyner, A.L., 2012. Limb anterior-posterior polarity integrates activator and repressor functions of GLI2 as well as GLI3. Dev. Biol. vol. 370, pp. 110-124.
    • (2012) Dev. Biol. , vol.370 , pp. 110-124
    • Bowers, M.1    Eng, L.2    Lao, Z.3    Turnbull, R.K.4    Bao, X.5    Riedel, E.6    Mackem, S.7    Joyner, A.L.8
  • 5
    • 0040976312 scopus 로고    scopus 로고
    • Evidence for genetic control of Sonic hedgehog by Gli3 in mouse limb development
    • Buscher D., Bosse B., Heymer J., Ruther U. Evidence for genetic control of Sonic hedgehog by Gli3 in mouse limb development. Mech. Dev. 1997, 62:175-182.
    • (1997) Mech. Dev. , vol.62 , pp. 175-182
    • Buscher, D.1    Bosse, B.2    Heymer, J.3    Ruther, U.4
  • 6
    • 0035881926 scopus 로고    scopus 로고
    • Manifestation of the limb prepattern: limb development in the absence of sonic hedgehog function
    • Chiang C., Litingtung Y., Harris M.P., Simandl B.K., Li Y., Beachy P.A., Fallon J.F. Manifestation of the limb prepattern: limb development in the absence of sonic hedgehog function. Dev. Biol. 2001, 236:421-435.
    • (2001) Dev. Biol. , vol.236 , pp. 421-435
    • Chiang, C.1    Litingtung, Y.2    Harris, M.P.3    Simandl, B.K.4    Li, Y.5    Beachy, P.A.6    Fallon, J.F.7
  • 8
    • 0031855859 scopus 로고    scopus 로고
    • Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice
    • Ding Q., Motoyama J., Gasca S., Mo R., Sasaki H., Rossant J., Hui C.C. Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice. Development 1998, 125:2533-2543.
    • (1998) Development , vol.125 , pp. 2533-2543
    • Ding, Q.1    Motoyama, J.2    Gasca, S.3    Mo, R.4    Sasaki, H.5    Rossant, J.6    Hui, C.C.7
  • 9
    • 0030027059 scopus 로고    scopus 로고
    • Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog
    • Goodrich L.V., Johnson R.L., Milenkovic L., McMahon J.A., Scott M.P. Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog. Genes Dev. 1996, 10:301-312.
    • (1996) Genes Dev. , vol.10 , pp. 301-312
    • Goodrich, L.V.1    Johnson, R.L.2    Milenkovic, L.3    McMahon, J.A.4    Scott, M.P.5
  • 10
    • 63349088603 scopus 로고    scopus 로고
    • A SHH-independent regulation of Gli3 is a significant determinant of anteroposterior patterning of the limb bud
    • Hill P., Gotz K., Ruther U. A SHH-independent regulation of Gli3 is a significant determinant of anteroposterior patterning of the limb bud. Dev. Biol. 2009, 328:506-516.
    • (2009) Dev. Biol. , vol.328 , pp. 506-516
    • Hill, P.1    Gotz, K.2    Ruther, U.3
  • 11
    • 0027478216 scopus 로고
    • A mouse model of greig cephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 gene
    • Hui C.C., Joyner A.L. A mouse model of greig cephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 gene. Nat. Genet. 1993, 3:241-246.
    • (1993) Nat. Genet. , vol.3 , pp. 241-246
    • Hui, C.C.1    Joyner, A.L.2
  • 12
    • 0033950445 scopus 로고    scopus 로고
    • Indian hedgehog coordinates endochondral bone growth and morphogenesis via parathyroid hormone related-protein-dependent and -independent pathways
    • Karp S.J., Schipani E., St-Jacques B., Hunzelman J., Kronenberg H., McMahon A.P. Indian hedgehog coordinates endochondral bone growth and morphogenesis via parathyroid hormone related-protein-dependent and -independent pathways. Development 2000, 127:543-548.
    • (2000) Development , vol.127 , pp. 543-548
    • Karp, S.J.1    Schipani, E.2    St-Jacques, B.3    Hunzelman, J.4    Kronenberg, H.5    McMahon, A.P.6
  • 13
    • 21344455343 scopus 로고    scopus 로고
    • Early developmental arrest of mammalian limbs lacking HoxA/HoxD gene function
    • Kmita M., Tarchini B., Zakany J., Logan M., Tabin C.J., Duboule D. Early developmental arrest of mammalian limbs lacking HoxA/HoxD gene function. Nature 2005, 435:1113-1116.
    • (2005) Nature , vol.435 , pp. 1113-1116
    • Kmita, M.1    Tarchini, B.2    Zakany, J.3    Logan, M.4    Tabin, C.J.5    Duboule, D.6
  • 14
    • 0035213877 scopus 로고    scopus 로고
    • Some distal limb structures develop in mice lacking Sonic hedgehog signaling
    • Kraus P., Fraidenraich D., Loomis C.A. Some distal limb structures develop in mice lacking Sonic hedgehog signaling. Mech. Dev. 2001, 100:45-58.
    • (2001) Mech. Dev. , vol.100 , pp. 45-58
    • Kraus, P.1    Fraidenraich, D.2    Loomis, C.A.3
  • 15
    • 0037194765 scopus 로고    scopus 로고
    • Shh and Gli3 are dispensable for limb skeleton formation but regulate digit number and identity
    • Litingtung Y., Dahn R.D., Li Y., Fallon J.F., Chiang C. Shh and Gli3 are dispensable for limb skeleton formation but regulate digit number and identity. Nature 2002, 418:979-983.
    • (2002) Nature , vol.418 , pp. 979-983
    • Litingtung, Y.1    Dahn, R.D.2    Li, Y.3    Fallon, J.F.4    Chiang, C.5
  • 16
    • 0036076389 scopus 로고    scopus 로고
    • Expression of Cre Recombinase in the developing mouse limb bud driven by a Prxl enhancer
    • Logan M., Martin J.F., Nagy A., Lobe C., Olson E.N., Tabin C.J. Expression of Cre Recombinase in the developing mouse limb bud driven by a Prxl enhancer. Genesis 2002, 33:77-80.
    • (2002) Genesis , vol.33 , pp. 77-80
    • Logan, M.1    Martin, J.F.2    Nagy, A.3    Lobe, C.4    Olson, E.N.5    Tabin, C.J.6
  • 18
    • 0030601955 scopus 로고    scopus 로고
    • Sonic hedgehog differentially regulates expression of GLI and GLI3 during limb development
    • Marigo V., Johnson R.L., Vortkamp A., Tabin C.J. Sonic hedgehog differentially regulates expression of GLI and GLI3 during limb development. Dev. Biol. 1996, 180:273-283.
    • (1996) Dev. Biol. , vol.180 , pp. 273-283
    • Marigo, V.1    Johnson, R.L.2    Vortkamp, A.3    Tabin, C.J.4
  • 19
    • 2642595047 scopus 로고    scopus 로고
    • The roles of FGFs in the early development of vertebrate limbs
    • Martin G.R. The roles of FGFs in the early development of vertebrate limbs. Genes Dev. 1998, 12:1571-1586.
    • (1998) Genes Dev. , vol.12 , pp. 1571-1586
    • Martin, G.R.1
  • 20
    • 0031679850 scopus 로고    scopus 로고
    • Gli2 is required for induction of floor plate and adjacent cells, but not most ventral neurons in the mouse central nervous system
    • Matise M.P., Epstein D.J., Park H.L., Platt K.A., Joyner A.L. Gli2 is required for induction of floor plate and adjacent cells, but not most ventral neurons in the mouse central nervous system. Development 1998, 125:2759-2770.
    • (1998) Development , vol.125 , pp. 2759-2770
    • Matise, M.P.1    Epstein, D.J.2    Park, H.L.3    Platt, K.A.4    Joyner, A.L.5
  • 23
    • 33646270662 scopus 로고    scopus 로고
    • Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation
    • Pan Y., Bai C.B., Joyner A.L., Wang B. Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation. Mol. Cell Biol. 2006, 26:3365-3377.
    • (2006) Mol. Cell Biol. , vol.26 , pp. 3365-3377
    • Pan, Y.1    Bai, C.B.2    Joyner, A.L.3    Wang, B.4
  • 25
    • 0027760995 scopus 로고
    • Sonic hedgehog mediates the polarizing activity of the ZPA
    • Riddle R.D., Johnson R.L., Laufer E., Tabin C. Sonic hedgehog mediates the polarizing activity of the ZPA. Cell 1993, 75:1401-1416.
    • (1993) Cell , vol.75 , pp. 1401-1416
    • Riddle, R.D.1    Johnson, R.L.2    Laufer, E.3    Tabin, C.4
  • 26
    • 0030808324 scopus 로고    scopus 로고
    • The PDGF alpha receptor is required for neural crest cell development and for normal patterning of the somites
    • Soriano P. The PDGF alpha receptor is required for neural crest cell development and for normal patterning of the somites. Development 1997, 124:2691-2700.
    • (1997) Development , vol.124 , pp. 2691-2700
    • Soriano, P.1
  • 27
    • 0037083760 scopus 로고    scopus 로고
    • Mutual genetic antagonism involving GLI3 and dHAND prepatterns the vertebrate limb bud mesenchyme prior to SHH signaling
    • te Welscher P., Fernandez-Teran M., Ros M.A., Zeller R. Mutual genetic antagonism involving GLI3 and dHAND prepatterns the vertebrate limb bud mesenchyme prior to SHH signaling. Genes Dev. 2002, 16:421-426.
    • (2002) Genes Dev. , vol.16 , pp. 421-426
    • te Welscher, P.1    Fernandez-Teran, M.2    Ros, M.A.3    Zeller, R.4
  • 29
    • 33646869503 scopus 로고    scopus 로고
    • Multisite protein kinase A and glycogen synthase kinase 3{beta} phosphorylation leads to Gli3 ubiquitination by SCF{beta}TrCP
    • Tempe D., Casas M., Karaz S., Blanchet-Tournier M.F., Concordet J.P. Multisite protein kinase A and glycogen synthase kinase 3{beta} phosphorylation leads to Gli3 ubiquitination by SCF{beta}TrCP. Mol. Cell Biol. 2006, 26:4316-4326.
    • (2006) Mol. Cell Biol. , vol.26 , pp. 4316-4326
    • Tempe, D.1    Casas, M.2    Karaz, S.3    Blanchet-Tournier, M.F.4    Concordet, J.P.5
  • 30
    • 0025812172 scopus 로고
    • GLI3 zinc-finger gene interrupted by translocations in Greig syndrome families
    • Vortkamp A., Gessler M., Grzeschik K.H. GLI3 zinc-finger gene interrupted by translocations in Greig syndrome families. Nature 1991, 352:539-540.
    • (1991) Nature , vol.352 , pp. 539-540
    • Vortkamp, A.1    Gessler, M.2    Grzeschik, K.H.3
  • 31
    • 0034681266 scopus 로고    scopus 로고
    • Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb
    • Wang B., Fallon J.F., Beachy P.A. Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb. Cell 2000, 100:423-434.
    • (2000) Cell , vol.100 , pp. 423-434
    • Wang, B.1    Fallon, J.F.2    Beachy, P.A.3
  • 32
    • 30444437000 scopus 로고    scopus 로고
    • Evidence for the direct involvement of {beta}TrCP in Gli3 protein processing
    • Wang B., Li Y. Evidence for the direct involvement of {beta}TrCP in Gli3 protein processing. Proc. Natl. Acad. Sci. USA 2006, 103:33-38.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 33-38
    • Wang, B.1    Li, Y.2
  • 33
    • 33947411380 scopus 로고    scopus 로고
    • A hypermorphic mouse Gli3 allele results in a polydactylous limb phenotype
    • Wang C., Pan Y., Wang B. A hypermorphic mouse Gli3 allele results in a polydactylous limb phenotype. Dev. Dyn. 2007, 236:769-776.
    • (2007) Dev. Dyn. , vol.236 , pp. 769-776
    • Wang, C.1    Pan, Y.2    Wang, B.3
  • 34
    • 34247569471 scopus 로고    scopus 로고
    • The Shh-independent activator function of the full-length Gli3 protein and its role in vertebrate limb digit patterning
    • Wang C., Ruther U., Wang B. The Shh-independent activator function of the full-length Gli3 protein and its role in vertebrate limb digit patterning. Dev. Biol. 2007, 305:460-469.
    • (2007) Dev. Biol. , vol.305 , pp. 460-469
    • Wang, C.1    Ruther, U.2    Wang, B.3
  • 35
    • 0001244671 scopus 로고
    • Whole mount in situ hybridization of vertebrate embryos
    • IRL Press, Oxford, D. Wilkinson (Ed.)
    • Wilkinson D. Whole mount in situ hybridization of vertebrate embryos. In Situ Hybridization: A Practical Approach 1992, IRL Press, Oxford, pp. 75-84. D. Wilkinson (Ed.).
    • (1992) In Situ Hybridization: A Practical Approach , pp. 75-84
    • Wilkinson, D.1
  • 37
    • 0032902095 scopus 로고    scopus 로고
    • Hox genes in digit development and evolution
    • Zakany J., Duboule D. Hox genes in digit development and evolution. Cell Tissue Res. 1999, 296:19-25.
    • (1999) Cell Tissue Res. , vol.296 , pp. 19-25
    • Zakany, J.1    Duboule, D.2
  • 38
    • 0041030051 scopus 로고    scopus 로고
    • Signal relay by BMP antagonism controls the SHH/FGF4 feedback loop in vertebrate limb buds
    • Zuniga A., Haramis A.P., McMahon A.P., Zeller R. Signal relay by BMP antagonism controls the SHH/FGF4 feedback loop in vertebrate limb buds. Nature 1999, 401:598-602.
    • (1999) Nature , vol.401 , pp. 598-602
    • Zuniga, A.1    Haramis, A.P.2    McMahon, A.P.3    Zeller, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.