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Volumn 39, Issue 2, 2014, Pages 281-302

Competing views on cancer

Author keywords

Cancer; Histogenesis; Intrinsically disordered proteins; Morphogenesis; Protein interaction network; Stroma epithelium interaction; Tissue organization field theory

Indexed keywords

MYC PROTEIN; INTRINSICALLY DISORDERED PROTEIN;

EID: 84904208474     PISSN: 02505991     EISSN: 09737138     Source Type: Journal    
DOI: 10.1007/s12038-013-9403-y     Document Type: Review
Times cited : (49)

References (169)
  • 1
    • 78650354119 scopus 로고    scopus 로고
    • Model organisms and human health
    • Alberts B 2010 Model organisms and human health. Science 330 1724
    • (2010) Science , vol.330 , pp. 1724
    • Alberts, B.1
  • 8
    • 72949092693 scopus 로고    scopus 로고
    • Unraveling the potential of intrinsically disordered proteins as drug targets: Application to Mycobacterium tuberculosis
    • Anurag M and Dash D 2009 Unraveling the potential of intrinsically disordered proteins as drug targets: application to Mycobacterium tuberculosis. Mol. Biosyst. 5 1752-1757
    • (2009) Mol. Biosyst. , vol.5 , pp. 1752-1757
    • Anurag, M.1    Dash, D.2
  • 9
    • 49149115868 scopus 로고    scopus 로고
    • The RAS/MAPK syndromes: Novel roles of the RAS pathway in human genetic disorders
    • Aoki Y, Niihori T, Narumi Y, Kure S and Matsubara Y 2008 The RAS/MAPK syndromes: novel roles of the RAS pathway in human genetic disorders. Hum. Mutat. 29 992-1006
    • (2008) Hum. Mutat. , vol.29 , pp. 992-1006
    • Aoki, Y.1    Niihori, T.2    Narumi, Y.3    Kure, S.4    Matsubara, Y.5
  • 11
    • 0014333785 scopus 로고
    • Biology as an autonomous science
    • Ayala FJ 1968 Biology as an autonomous science. Am. Sci. 56 207-221
    • (1968) Am. Sci. , vol.56 , pp. 207-221
    • Ayala, F.J.1
  • 12
    • 84866447416 scopus 로고    scopus 로고
    • The evolving concept of cancer and metastasis stem cells
    • Baccelli I and Trumpp A 2012 The evolving concept of cancer and metastasis stem cells. J. Cell Biol. 198 281-93
    • (2012) J. Cell Biol. , vol.198 , pp. 281-293
    • Baccelli, I.1    Trumpp, A.2
  • 13
    • 84880270290 scopus 로고    scopus 로고
    • Identification of a population of blood circulating tumor cells from breast cancer patients that initiates metastasis in a xenograft assay
    • Baccelli I, Schneeweiss A, Riethdorf S, Stenzinger A, Schillert A, Vogel V, Klein C, Saini M, et al. 2013 Identification of a population of blood circulating tumor cells from breast cancer patients that initiates metastasis in a xenograft assay. Nat. Biotechnol. 31 539-44
    • (2013) Nat. Biotechnol. , vol.31 , pp. 539-544
    • Baccelli, I.1    Schneeweiss, A.2    Riethdorf, S.3    Stenzinger, A.4    Schillert, A.5    Vogel, V.6    Klein, C.7    Saini, M.8
  • 14
    • 84874821233 scopus 로고    scopus 로고
    • Paradoxes in carcinogenesis should spur new avenues of research: An historical perspective
    • Baker SG 2012 Paradoxes in carcinogenesis should spur new avenues of research: an historical perspective. Disrup. Sci. Technol. 1 100-107
    • (2012) Disrup. Sci. Technol. , vol.1 , pp. 100-107
    • Baker, S.G.1
  • 15
    • 34848857387 scopus 로고    scopus 로고
    • Paradoxes in carcinogenesis: New opportunities for research directions
    • Baker SG and Kramer BS 2007 Paradoxes in carcinogenesis: new opportunities for research directions. BMC Cancer 7 151
    • (2007) BMC Cancer , vol.7 , pp. 151
    • Baker, S.G.1    Kramer, B.S.2
  • 16
    • 64049111618 scopus 로고    scopus 로고
    • Plausibility of stromal initiation of epithelial cancers without a mutation in the epithelium: A computer simulation of morphostats
    • Baker SG, Soto AM, Sonnenschein C, Cappuccio A, Potter JD and Kramer BS 2009 Plausibility of stromal initiation of epithelial cancers without a mutation in the epithelium: a computer simulation of morphostats. BMC Cancer 9 89
    • (2009) BMC Cancer , vol.9 , pp. 89
    • Baker, S.G.1    Soto, A.M.2    Sonnenschein, C.3    Cappuccio, A.4    Potter, J.D.5    Kramer, B.S.6
  • 17
    • 0001410750 scopus 로고
    • A new factor in evolution
    • Baldwin JM 1896 A new factor in evolution. Am. Nat. 30 441-451
    • (1896) Am. Nat. , vol.30 , pp. 441-451
    • Baldwin, J.M.1
  • 18
    • 0034161922 scopus 로고    scopus 로고
    • Irradiated mammary gland stroma promotes the expression of tumorigenic potential by unirradiated epithelial cells
    • Barcellos-Hoff MH and Ravani SA 2000 Irradiated mammary gland stroma promotes the expression of tumorigenic potential by unirradiated epithelial cells. Cancer Res. 60 1254-1260 (Pubitemid 30151992)
    • (2000) Cancer Research , vol.60 , Issue.5 , pp. 1254-1260
    • Barcellos-Hoff, M.H.1    Ravani, S.A.2
  • 19
    • 79952377463 scopus 로고    scopus 로고
    • Resistance, epigenetics and the cancer ecosystem
    • Baylin SB 2011 Resistance, epigenetics and the cancer ecosystem. Nat. Med. 17 288-289
    • (2011) Nat. Med. , vol.17 , pp. 288-289
    • Baylin, S.B.1
  • 20
    • 84860826713 scopus 로고    scopus 로고
    • A core subunit of Polycomb repressive complex 1 is broadly conserved in function but not primary sequence
    • Beh LY, Colwell LJ and Francis NJ 2012 A core subunit of Polycomb repressive complex 1 is broadly conserved in function but not primary sequence. Proc. Acad. Natl. Acad. Sci. USA 109 E1063-E1071
    • (2012) Proc. Acad. Natl. Acad. Sci. USA , vol.109
    • Beh, L.Y.1    Colwell, L.J.2    Francis, N.J.3
  • 21
    • 0028986561 scopus 로고
    • An investigation into the role of phenotypic plasticity in evolution
    • DOI 10.1006/jtbi.1995.0019
    • Behera N and Nanjundiah V 1995 An investigation into the role of phenotypic plasticity in evolution. J. Theor. Biol. 172 225-234 (Pubitemid 26447560)
    • (1995) Journal of Theoretical Biology , vol.172 , Issue.3 , pp. 225-234
    • Behera, N.1    Nanjundiah, V.2
  • 22
    • 0029961136 scopus 로고    scopus 로고
    • The consequences of phenotypic plasticity in cyclically varying environments: A genetic algorithm study
    • DOI 10.1006/jtbi.1996.0012
    • Behera N and Nanjundiah V 1996 The consequences of phenotypic plasticity in cyclically varying environments: a genetic algorithm study. J. Theor. Biol. 178 135-144 (Pubitemid 26118843)
    • (1996) Journal of Theoretical Biology , vol.178 , Issue.2 , pp. 135-144
    • Behera, N.1    Nanjundiah, V.2
  • 23
    • 0344120676 scopus 로고    scopus 로고
    • Phenotypic plasticity can potentiate rapid evolutionary change
    • DOI 10.1016/j.jtbi.2003.08.011
    • Behera N and Nanjundiah V 2004 Phenotypic plasticity can potentiate rapid evolutionary change. J. Theor. Biol. 226 177-184 (Pubitemid 37468396)
    • (2004) Journal of Theoretical Biology , vol.226 , Issue.2 , pp. 177-184
    • Behera, N.1    Nanjundiah, V.2
  • 24
    • 84865798159 scopus 로고    scopus 로고
    • Bacterial survival strategies suggest rethinking cancer cooperativity
    • Ben-Jacob E, Coffey DS and Levine H 2012 Bacterial survival strategies suggest rethinking cancer cooperativity. Trends Microbiol. 20 403-410
    • (2012) Trends Microbiol. , vol.20 , pp. 403-410
    • Ben-Jacob, E.1    Coffey, D.S.2    Levine, H.3
  • 25
    • 9244227134 scopus 로고    scopus 로고
    • Stromal fibroblasts in cancer initiation and progression
    • DOI 10.1038/nature03096
    • Bhowmick NA, Neilson EG and Moses HL 2004 Stromal fibroblasts in cancer initiation and progression. Nature 432 332-337 (Pubitemid 39551661)
    • (2004) Nature , vol.432 , Issue.7015 , pp. 332-337
    • Bhowmick, N.A.1    Neilson, E.G.2    Moses, H.L.3
  • 29
    • 84873843971 scopus 로고    scopus 로고
    • Physical forces and non-linear dynamics mould fractal cell shape: Quantitative morphological parameters and cell phenotype
    • Bizzarri M, Pasqualato A, Cucina A and Pasta V 2013 Physical forces and non-linear dynamics mould fractal cell shape: quantitative morphological parameters and cell phenotype. Histol. Histopathol. 28 155-274
    • (2013) Histol. Histopathol. , vol.28 , pp. 155-274
    • Bizzarri, M.1    Pasqualato, A.2    Cucina, A.3    Pasta, V.4
  • 30
    • 0030789242 scopus 로고    scopus 로고
    • Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
    • DOI 10.1038/nm0797-730
    • Bonnet D and Dick JE 1997 Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat. Med. 3 730-737 (Pubitemid 27298715)
    • (1997) Nature Medicine , vol.3 , Issue.7 , pp. 730-737
    • Bonnet, D.1    Dick, J.E.2
  • 31
    • 79951509549 scopus 로고    scopus 로고
    • The normal mammary microenvironment suppresses the tumorigenic phenotype of mouse mammary tumor virus-neu-transformed mammary tumor cells
    • Booth BW, Boulanger CA anderson LH and Smith GH 2011 The normal mammary microenvironment suppresses the tumorigenic phenotype of mouse mammary tumor virus-neu-transformed mammary tumor cells. Oncogene 30 679-869
    • (2011) Oncogene , vol.30 , pp. 679-869
    • Booth, B.W.1    Boulanger, C.A.2    Anderson, L.H.3    Smith, G.H.4
  • 33
    • 25444495269 scopus 로고    scopus 로고
    • Migrating cancer stem cells - An integrated concept of malignant tumour progression
    • DOI 10.1038/nrc1694, PII N1694
    • Brabletz T, Jung A, Spaderna S, Hlubek F and Kirchner T 2005 Opinion: migrating cancer stem cells - an integrated concept of malignant tumour progression. Nat. Rev. Cancer 5 744-749 (Pubitemid 41486367)
    • (2005) Nature Reviews Cancer , vol.5 , Issue.9 , pp. 744-749
    • Brabletz, T.1    Jung, A.2    Spaderna, S.3    Hlubek, F.4    Kirchner, T.5
  • 36
  • 37
    • 84859158880 scopus 로고    scopus 로고
    • The CD47-SIRPalpha pathway in cancer immune evasion and potential therapeutic implications
    • Chao MP, Weissman IL and Majeti R 2012 The CD47-SIRPalpha pathway in cancer immune evasion and potential therapeutic implications. Curr. Opin. Immunol. 24 225-232
    • (2012) Curr. Opin. Immunol. , vol.24 , pp. 225-232
    • Chao, M.P.1    Weissman, I.L.2    Majeti, R.3
  • 38
    • 43749084585 scopus 로고    scopus 로고
    • Recent advances in cancer stem cells
    • DOI 10.1016/j.gde.2008.01.017, PII S0959437X08000221
    • Cho RW and Clarke MF 2008 Recent advances in cancer stem cells. Curr. Opin. Genet. Dev. 18 48-53 (Pubitemid 351694448)
    • (2008) Current Opinion in Genetics and Development , vol.18 , Issue.1 , pp. 48-53
    • Cho, R.W.1    Clarke, M.F.2
  • 39
    • 84872445265 scopus 로고    scopus 로고
    • Neutralizing tumor-promoting chronic inflammation: A magic bullet?
    • Coussens LM, Zitvogel L and Palucka AK 2013 Neutralizing tumor-promoting chronic inflammation: a magic bullet? Science 339 286-91
    • (2013) Science , vol.339 , pp. 286-291
    • Coussens, L.M.1    Zitvogel, L.2    Palucka, A.K.3
  • 40
    • 84883419186 scopus 로고    scopus 로고
    • Promiscuity as a functional trait: Intrinsically disordered regions as central players of interactomes
    • Cumberworth A, Lamour G, Babu MM and Gsponer J 2013 Promiscuity as a functional trait: intrinsically disordered regions as central players of interactomes. Biochem. J. 454 361-369
    • (2013) Biochem. J. , vol.454 , pp. 361-369
    • Cumberworth, A.1    Lamour, G.2    Babu, M.M.3    Gsponer, J.4
  • 41
    • 34047096557 scopus 로고    scopus 로고
    • Cancer stem cells: Models and concepts
    • DOI 10.1146/annurev.med.58.062105.204854
    • Dalerba P, Cho RW and Clarke MF 2007 Cancer stem cells: models and concepts. Annu. Rev. Med. 58 267-284 (Pubitemid 46706514)
    • (2007) Annual Review of Medicine , vol.58 , pp. 267-284
    • Dalerba, P.1    Cho, R.W.2    Clarke, M.F.3
  • 43
    • 16844368698 scopus 로고    scopus 로고
    • Tumour stem cells and drug resistance
    • DOI 10.1038/nrc1590
    • Dean M, Fojo T and Bates S 2005 Tumour stem cells and drug resistance. Nat. Rev. Cancer 5 275-84 (Pubitemid 40488633)
    • (2005) Nature Reviews Cancer , vol.5 , Issue.4 , pp. 275-284
    • Dean, M.1    Fojo, T.2    Bates, S.3
  • 44
    • 84860368661 scopus 로고    scopus 로고
    • Transcriptional mechanisms of developmental cell cycle arrest: Problems and models
    • Deves M and Bourrat F 2012 Transcriptional mechanisms of developmental cell cycle arrest: problems and models. Semin. Cell Dev. Biol. 23 290-297
    • (2012) Semin. Cell Dev. Biol. , vol.23 , pp. 290-297
    • Deves, M.1    Bourrat, F.2
  • 46
    • 0002224909 scopus 로고
    • Punctuated equilibria: An alternative to phyletic gradualism
    • Eldredge N and Gould SJ 1972 Punctuated equilibria: an alternative to phyletic gradualism. Models Paleobiol. 82 115
    • (1972) Models Paleobiol. , vol.82 , pp. 115
    • Eldredge, N.1    Gould, S.J.2
  • 48
    • 40849139208 scopus 로고    scopus 로고
    • Epigenetics in cancer
    • Esteller M 2008 Epigenetics in cancer. New Engl. J. Med. 358 1148-59
    • (2008) New Engl. J. Med. , vol.358 , pp. 1148-1159
    • Esteller, M.1
  • 49
    • 34548217968 scopus 로고    scopus 로고
    • Human breast cancer stem cell markers CD44 and CD24: Enriching for cells with functional properties in mice or in man
    • Fillmore C and Kuperwasser C 2007 Human breast cancer stem cell markers CD44 and CD24: enriching for cells with functional properties in mice or in man. Breast Cancer Res. 9 303
    • (2007) Breast Cancer Res. , vol.9 , pp. 303
    • Fillmore, C.1    Kuperwasser, C.2
  • 50
    • 84875211731 scopus 로고    scopus 로고
    • Cancer heterogeneity: Implications for targeted therapeutics
    • Fisher R, Pusztai L and Swanton C 2013 Cancer heterogeneity: implications for targeted therapeutics. Brit. J. Cancer 108 479-85
    • (2013) Brit. J. Cancer , vol.108 , pp. 479-485
    • Fisher, R.1    Pusztai, L.2    Swanton, C.3
  • 52
    • 84859517054 scopus 로고    scopus 로고
    • Intrinsic protein flexibility in regulation of cell proliferation: Advantages for signaling and opportunities for novel therapeutics
    • Follis AV, Galea CA and Kriwacki RW 2012 Intrinsic protein flexibility in regulation of cell proliferation: advantages for signaling and opportunities for novel therapeutics. Adv. Exp. Med. Biol. 725 27-49
    • (2012) Adv. Exp. Med. Biol. , vol.725 , pp. 27-49
    • Follis, A.V.1    Galea, C.A.2    Kriwacki, R.W.3
  • 53
    • 80053538947 scopus 로고    scopus 로고
    • ADNA repair complex functions as an Oct4/Sox2 coactivator in embryonic stem cells
    • Fong YW, Inouye C, Yamaguchi T, Cattoglio C, Grubisic I and Tjian R 2011 ADNA repair complex functions as an Oct4/Sox2 coactivator in embryonic stem cells. Cell 147 120-131
    • (2011) Cell , vol.147 , pp. 120-131
    • Fong, Y.W.1    Inouye, C.2    Yamaguchi, T.3    Cattoglio, C.4    Grubisic, I.5    Tjian, R.6
  • 54
    • 0000812966 scopus 로고
    • Molecular configuration in sodium thymonucleate
    • Franklin RE and Gosling RG 1953 Molecular configuration in sodium thymonucleate. Nature 171 740-741
    • (1953) Nature , vol.171 , pp. 740-741
    • Franklin, R.E.1    Gosling, R.G.2
  • 55
    • 0033598978 scopus 로고    scopus 로고
    • Heterogeneity studies identify a subset of sporadic colorectal cancers without evidence for chromosomal or microsatellite instability
    • Georgiades IB, Curtis LJ, Morris RM, Bird CC and Wyllie AH 1999 Heterogeneity studies identify a subset of sporadic colorectal cancers without evidence for chromosomal or microsatellite instability. Oncogene 18 7933-7940 (Pubitemid 30050553)
    • (1999) Oncogene , vol.18 , Issue.56 , pp. 7933-7940
    • Georgiades, I.B.1    Curtis, L.J.2    Morris, R.M.3    Bird, C.C.4    Wyllie, A.H.5
  • 56
    • 0029958876 scopus 로고    scopus 로고
    • Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo
    • DOI 10.1084/jem.183.4.1797
    • Goodell MA, Brose K, Paradis G, Conner AS and Mulligan RC 1996 Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. J. Exp. Med. 183 1797-1806 (Pubitemid 26134320)
    • (1996) Journal of Experimental Medicine , vol.183 , Issue.4 , pp. 1797-1806
    • Goodell, M.A.1    Brose, K.2    Paradis, G.3    Conner, A.S.4    Mulligan, R.C.5
  • 57
    • 33847370301 scopus 로고    scopus 로고
    • Tumour metabolomics in animal models of human cancer
    • DOI 10.1021/pr060464h
    • Griffin JL and Kauppinen RA 2007 Tumour metabolomics in animal models of human cancer. J. Proteome Res. 6 498-505 (Pubitemid 46340153)
    • (2007) Journal of Proteome Research , vol.6 , Issue.2 , pp. 498-505
    • Griffin, J.L.1    Kauppinen, R.A.2
  • 59
    • 80051967505 scopus 로고    scopus 로고
    • Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells
    • Gupta PB, Fillmore CM, Jiang G, Shapira SD, Tao K, Kuperwasser C and Lander ES 2011 Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells. Cell 146 633-44
    • (2011) Cell , vol.146 , pp. 633-644
    • Gupta, P.B.1    Fillmore, C.M.2    Jiang, G.3    Shapira, S.D.4    Tao, K.5    Kuperwasser, C.6    Lander, E.S.7
  • 60
    • 0036561908 scopus 로고    scopus 로고
    • Modelling the molecular circuitry of cancer
    • Hahn WC and Weinberg RA 2002 Modelling the molecular circuitry of cancer. Nat. Rev. Cancer 2 331-341 (Pubitemid 37328946)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.5 , pp. 331-341
    • Hahn, W.C.1    Weinberg, R.A.2
  • 61
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D and Weinberg RA 2000 The hallmarks of cancer. Cell 100 57-70 (Pubitemid 30046295)
    • (2000) Cell , vol.100 , Issue.1 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 62
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D and Weinberg RA 2011 Hallmarks of cancer: the next generation. Cell 144 646-674
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 66
    • 0000211184 scopus 로고
    • How learning can guide evolution
    • Hinton GE and Nowlan SJ 1987 How learning can guide evolution. Complex Syst. 1 495-502
    • (1987) Complex Syst. , vol.1 , pp. 495-502
    • Hinton, G.E.1    Nowlan, S.J.2
  • 67
    • 84866000928 scopus 로고    scopus 로고
    • Tumor progression: Chance and necessity in Darwinian and Lamarckian somatic (mutationless) evolution
    • Huang S 2012 Tumor progression: chance and necessity in Darwinian and Lamarckian somatic (mutationless) evolution. Prog. Biophys. Mol. Biol. 110 69-86
    • (2012) Prog. Biophys. Mol. Biol. , vol.110 , pp. 69-86
    • Huang, S.1
  • 68
    • 84876312818 scopus 로고    scopus 로고
    • When peers are not peers and don't know it: The Dunning-Kruger effect and self-fulfilling prophecy in peer-review
    • Huang S 2013 When peers are not peers and don't know it: The Dunning-Kruger effect and self-fulfilling prophecy in peer-review. BioEssays: News Rev. Mol. Cell. Dev. Biol. 35 414-416
    • (2013) BioEssays: News Rev. Mol. Cell. Dev. Biol. , vol.35 , pp. 414-416
    • Huang, S.1
  • 69
    • 34247535888 scopus 로고    scopus 로고
    • A non-genetic basis for cancer progression and metastasis: Self-organizing attractors in cell regulatory networks
    • Huang S and Ingber DE 2006 A non-genetic basis for cancer progression and metastasis: self-organizing attractors in cell regulatory networks. Breast Dis. 26 27-54 (Pubitemid 46647413)
    • (2006) Breast Disease , vol.26 , Issue.1 , pp. 27-54
    • Huang, S.1    Ingber, D.E.2
  • 70
    • 70349330663 scopus 로고    scopus 로고
    • Cancer attractors: A systems view of tumors from a gene network dynamics and developmental perspective
    • Huang S, Ernberg I and Kauffman S 2009 Cancer attractors: a systems view of tumors from a gene network dynamics and developmental perspective. Semin. Cell Dev. Biol. 20 869-876
    • (2009) Semin. Cell Dev. Biol. , vol.20 , pp. 869-876
    • Huang, S.1    Ernberg, I.2    Kauffman, S.3
  • 72
    • 2042435768 scopus 로고
    • Totipotency and normal differentiation of single teratocarcinoma cells cloned by injection into blastocysts
    • Illmensee K and Mintz B 1976 Totipotency and normal differentiation of single teratocarcinoma cells cloned by injection into blastocysts. Proc. Acad. Natl. Acad. Sci. USA 73 549-53
    • (1976) Proc. Acad. Natl. Acad. Sci. USA , vol.73 , pp. 549-553
    • Illmensee, K.1    Mintz, B.2
  • 74
    • 77957350610 scopus 로고    scopus 로고
    • Identification of driver and passenger DNA methylation in cancer by epigenomic analysis
    • Kalari S and Pfeifer GP 2010 Identification of driver and passenger DNA methylation in cancer by epigenomic analysis. Adv. Genet. 70 277-308
    • (2010) Adv. Genet. , vol.70 , pp. 277-308
    • Kalari, S.1    Pfeifer, G.P.2
  • 76
    • 84873084388 scopus 로고    scopus 로고
    • Variable clonal repopulation dynamics influence chemotherapy response in colorectal cancer
    • Kreso A, O'Brien CA, van Galen P, Gan OI, Notta F, Brown AM, Ng K, Ma J, et al. 2013 Variable clonal repopulation dynamics influence chemotherapy response in colorectal cancer. Science 339 543-548
    • (2013) Science , vol.339 , pp. 543-548
    • Kreso, A.1    O'Brien, C.A.2    Van Galen, P.3    Gan, O.I.4    Notta, F.5    Brown, A.M.6    Ng, K.7    Ma, J.8
  • 81
    • 84863035821 scopus 로고    scopus 로고
    • Cancer stem cells: Distinct entities or dynamically regulated phenotypes?
    • Li Y and Laterra J 2012 Cancer stem cells: distinct entities or dynamically regulated phenotypes? Cancer Res. 72 576-80
    • (2012) Cancer Res. , vol.72 , pp. 576-580
    • Li, Y.1    Laterra, J.2
  • 84
    • 77649208749 scopus 로고    scopus 로고
    • Cancer stem cells: A reality, a myth, a fuzzy concept or a misnomer? An analysis
    • Maenhaut C, Dumont JE, Roger PP and van Staveren WC 2010 Cancer stem cells: a reality, a myth, a fuzzy concept or a misnomer? An analysis. Carcinogenesis 31 149-158
    • (2010) Carcinogenesis , vol.31 , pp. 149-158
    • Maenhaut, C.1    Dumont, J.E.2    Roger, P.P.3    Van Staveren, W.C.4
  • 86
    • 27544510187 scopus 로고    scopus 로고
    • Stromal regulation of neoplastic development: Age-dependent normalization of neoplastic mammary cells by mammary stroma
    • Maffini MV, Calabro JM, Soto AM and Sonnenschein C 2005 Stromal regulation of neoplastic development: age-dependent normalization of neoplastic mammary cells by mammary stroma. Am. J. Pathol. 167 1405-1410 (Pubitemid 41541426)
    • (2005) American Journal of Pathology , vol.167 , Issue.5 , pp. 1405-1410
    • Maffini, M.V.1    Calabro, J.M.2    Soto, A.M.3    Sonnenschein, C.4
  • 89
    • 0036007425 scopus 로고    scopus 로고
    • The intestinal epithelial stem cell
    • DOI 10.1002/bies.10028
    • Marshman E, Booth C and Potten CS 2002 The intestinal epithelial stem cell. BioEssays: News Rev. Mol. Cell. Dev. Biol. 24 91-98 (Pubitemid 34108424)
    • (2002) BioEssays , vol.24 , Issue.1 , pp. 91-98
    • Marshman, E.1    Booth, C.2    Potten, C.S.3
  • 91
    • 84873314642 scopus 로고    scopus 로고
    • Cancer cell phenotypes, in fifty shades of grey
    • Cancer
    • Marusyk A and Polyak K 2013 Cancer. Cancer cell phenotypes, in fifty shades of grey. Science 339 528-9
    • (2013) Science , vol.339 , pp. 528-529
    • Marusyk, A.1    Polyak, K.2
  • 92
    • 60749092460 scopus 로고    scopus 로고
    • Epigenetics and cancer without genomic instability
    • McKenna ES and Roberts CW 2009 Epigenetics and cancer without genomic instability. Cell Cycle 8 23-26
    • (2009) Cell Cycle , vol.8 , pp. 23-26
    • McKenna, E.S.1    Roberts, C.W.2
  • 93
    • 14044250003 scopus 로고    scopus 로고
    • Stroma is not a major target in DMBA-mediated tumorigenesis of mouse mammary preneoplasia
    • DOI 10.1242/jcs.01597
    • Medina D and Kittrell F 2005 Stroma is not a major target in DMBA-mediated tumorigenesis of mouse mammary preneoplasia. J. Cell Sci. 118 123-127 (Pubitemid 40277110)
    • (2005) Journal of Cell Science , vol.118 , Issue.1 , pp. 123-127
    • Medina, D.1    Kittrell, F.2
  • 95
    • 0345366593 scopus 로고
    • Normal genetically mosaic mice produced from malignant teratocarcinoma cells
    • Mintz B and Illmensee K 1975 Normal genetically mosaic mice produced from malignant teratocarcinoma cells. Proc. Acad. Natl. Acad. Sci. USA 72 3585-9
    • (1975) Proc. Acad. Natl. Acad. Sci. USA , vol.72 , pp. 3585-3589
    • Mintz, B.1    Illmensee, K.2
  • 96
    • 0001730968 scopus 로고
    • On modification and variation
    • Morgan CL 1896 On modification and variation. Science 4 733-740
    • (1896) Science , vol.4 , pp. 733-740
    • Morgan, C.L.1
  • 97
    • 33846230449 scopus 로고    scopus 로고
    • Clinical relevance of mutations and gene-expression changes in adult acute myeloid leukemia with normal cytogenetics: Are we ready for a prognostically prioritized molecular classification?
    • DOI 10.1182/blood-2006-06-001149
    • Mrozek K, Marcucci G, Paschka P, Whitman SP and Bloomfield CD 2007 Clinical relevance of mutations and gene-expression changes in adult acute myeloid leukemia with normal cytogenetics: are we ready for a prognostically prioritized molecular classification? Blood 109 431-448 (Pubitemid 46105936)
    • (2007) Blood , vol.109 , Issue.2 , pp. 431-448
    • Mrozek, K.1    Marcucci, G.2    Paschka, P.3    Whitman, S.P.4    Bloomfield, C.D.5
  • 98
    • 8144228952 scopus 로고    scopus 로고
    • Friends or foes - Bipolar effects of the tumour stroma in cancer
    • DOI 10.1038/nrc1477
    • Mueller MM and Fusenig NE 2004 Friends or foes - bipolar effects of the tumour stroma in cancer. Nat. Rev. Cancer 4 839-849 (Pubitemid 39472951)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.11 , pp. 839-849
    • Mueller, M.M.1    Fusenig, N.E.2
  • 100
    • 84869880156 scopus 로고    scopus 로고
    • Epigenetic alterations involved in cancer stem cell reprogramming
    • Munoz P, Iliou MS and Esteller M 2012 Epigenetic alterations involved in cancer stem cell reprogramming. Mol. Oncol. 6 620-636
    • (2012) Mol. Oncol. , vol.6 , pp. 620-636
    • Munoz, P.1    Iliou, M.S.2    Esteller, M.3
  • 101
    • 84855165141 scopus 로고    scopus 로고
    • CHD chromatin remodelers and the transcription cycle
    • Murawska M and Brehm A 2011 CHD chromatin remodelers and the transcription cycle. Transcription 2 244-253
    • (2011) Transcription , vol.2 , pp. 244-253
    • Murawska, M.1    Brehm, A.2
  • 102
    • 0343278984 scopus 로고    scopus 로고
    • Maze-solving by an amoeboid organism
    • Nakagaki T, Yamada H and Toth A 2000 Maze-solving by an amoeboid organism. Nature 407 470
    • (2000) Nature , vol.407 , pp. 470
    • Nakagaki, T.1    Yamada, H.2    Toth, A.3
  • 103
    • 79955975612 scopus 로고    scopus 로고
    • Radiation acts on the microenvironment to affect breast carcinogenesis by distinct mechanisms that decrease cancer latency and affect tumor type
    • Nguyen DH, Oketch-Rabah HA, Illa-Bochaca I, Geyer FC, Reis-Filho JS, Mao JH, Ravani SA, Zavadil J, et al. 2011 Radiation acts on the microenvironment to affect breast carcinogenesis by distinct mechanisms that decrease cancer latency and affect tumor type. Cancer Cell 19 640-651
    • (2011) Cancer Cell , vol.19 , pp. 640-651
    • Nguyen, D.H.1    Oketch-Rabah, H.A.2    Illa-Bochaca, I.3    Geyer, F.C.4    Reis-Filho, J.S.5    Mao, J.H.6    Ravani, S.A.7    Zavadil, J.8
  • 105
    • 0017167185 scopus 로고
    • The clonal evolution of tumor cell populations
    • Nowell PC 1976 The clonal evolution of tumor cell populations. Science 194 23-28
    • (1976) Science , vol.194 , pp. 23-28
    • Nowell, P.C.1
  • 106
    • 0033215242 scopus 로고    scopus 로고
    • Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium
    • Olumi AF, Grossfeld GD, Hayward SW, Carroll PR, Tlsty TD and Cunha GR 1999 Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium. Cancer Res. 59 5002-5011 (Pubitemid 29472907)
    • (1999) Cancer Research , vol.59 , Issue.19 , pp. 5002-5011
    • Olumi, A.F.1    Grossfeld, G.D.2    Hayward, S.W.3    Carroll, P.R.4    Tlsty, T.D.5    Cunha, G.R.6
  • 107
    • 0000311229 scopus 로고
    • Oytogenic and phylogenic variation
    • Osborn HF 1896 Oytogenic and phylogenic variation. Science 4 786-789
    • (1896) Science , vol.4 , pp. 786-789
    • Osborn, H.F.1
  • 108
    • 84859776256 scopus 로고    scopus 로고
    • Introduction of SV40ER and hTERT into mammospheres generates breast cancer cells with stem cell properties
    • Paranjape AN, Mandal T, Mukherjee G, Kumar MV, Sengupta K and Rangarajan A 2012 Introduction of SV40ER and hTERT into mammospheres generates breast cancer cells with stem cell properties. Oncogene 31 1896-1909
    • (2012) Oncogene , vol.31 , pp. 1896-1909
    • Paranjape, A.N.1    Mandal, T.2    Mukherjee, G.3    Kumar, M.V.4    Sengupta, K.5    Rangarajan, A.6
  • 109
    • 0345059767 scopus 로고    scopus 로고
    • Applying the principles of stem-cell biology to cancer
    • Pardal R, Clarke MF and Morrison SJ 2003 Applying the principles of stem-cell biology to cancer. Nat. Rev. Cancer 3 895-902 (Pubitemid 37500174)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.12 , pp. 895-902
    • Pardal, R.1    Clarke, M.F.2    Morrison, S.J.3
  • 110
    • 83455266856 scopus 로고    scopus 로고
    • The default state of the cell: Quiescence or proliferation?
    • Parr E 2012 The default state of the cell: quiescence or proliferation? BioEssays: News Rev. Mol. Cell. Dev. Biol. 34 36-37
    • (2012) BioEssays: News Rev. Mol. Cell. Dev. Biol. , vol.34 , pp. 36-37
    • Parr, E.1
  • 112
    • 77951898121 scopus 로고    scopus 로고
    • Hub promiscuity in protein-protein interaction networks
    • Patil A, Kinoshita K and Nakamura H 2010 Hub promiscuity in protein-protein interaction networks. Int. J. Mol. Sci. 11 1930-43
    • (2010) Int. J. Mol. Sci. , vol.11 , pp. 1930-1943
    • Patil, A.1    Kinoshita, K.2    Nakamura, H.3
  • 113
    • 0034877064 scopus 로고    scopus 로고
    • Philadelphia-positive B-cell acute lymphoblastic leukemia is initiated in an uncommitted progenitor cell
    • Perez-Losada J, Gutierrez-Cianca N and Sanchez-Garcia I 2001 Philadelphia-positive B-cell acute lymphoblastic leukemia is initiated in an uncommitted progenitor cell. Leukemia Lymphoma 42 569-576 (Pubitemid 32782762)
    • (2001) Leukemia and Lymphoma , vol.42 , Issue.4 , pp. 569-576
    • Perez-Losada, J.1    Gutierrez-Cianca, N.2    Sanchez-Garcia, I.3
  • 116
    • 77957970301 scopus 로고    scopus 로고
    • Epigenetic modifications and human disease
    • Portela A and Esteller M 2010 Epigenetic modifications and human disease. Nat. Biotechnol. 28 1057-1068
    • (2010) Nat. Biotechnol. , vol.28 , pp. 1057-1068
    • Portela, A.1    Esteller, M.2
  • 117
    • 0028172057 scopus 로고
    • Cancers beget mutations versus mutations beget cancers
    • Prehn RT 1994 Cancers beget mutations versus mutations beget cancers. Cancer Res. 54 5296-5300 (Pubitemid 24336016)
    • (1994) Cancer Research , vol.54 , Issue.20 , pp. 5296-5300
    • Prehn, R.T.1
  • 118
    • 84885762909 scopus 로고    scopus 로고
    • What lies beneath: Looking beyond tumor genetics shows the complexity of signaling networks underlying drug sensitivity
    • Quaranta V and Tyson DR 2013 What lies beneath: looking beyond tumor genetics shows the complexity of signaling networks underlying drug sensitivity. Sci. Signal 6 32
    • (2013) Sci. Signal , vol.6 , pp. 32
    • Quaranta, V.1    Tyson, D.R.2
  • 121
    • 1342288971 scopus 로고    scopus 로고
    • Comparative biology of mouse versus human cells: Modelling human cancer in mice
    • Rangarajan A and Weinberg RA 2003 Opinion: Comparative biology of mouse versus human cells: modelling human cancer in mice. Nat. Rev. Cancer 3 952-959 (Pubitemid 37500180)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.12 , pp. 952-959
    • Rangarajan, A.1    Weinberg, R.A.2
  • 122
    • 3142577806 scopus 로고
    • Baltimore: Johns Hopkins University Press
    • Rather LJ 1978 The genesis of cancer (Baltimore: Johns Hopkins University Press)
    • (1978) The Genesis of Cancer
    • Rather, L.J.1
  • 124
    • 0032569851 scopus 로고    scopus 로고
    • Hsp90 as a capacitor for morphological evolution
    • DOI 10.1038/24550
    • Rutherford SL and Lindquist S 1998 Hsp90 as a capacitor for morphological evolution. Nature 396 336-42 (Pubitemid 28557387)
    • (1998) Nature , vol.396 , Issue.6709 , pp. 336-342
    • Rutherford, S.L.1    Lindquist, S.2
  • 125
    • 79960715759 scopus 로고    scopus 로고
    • Systems biology beyond networks: Generating order from disorder through self-organization
    • Saetzler K, Sonnenschein C and Soto AM 2011 Systems biology beyond networks: generating order from disorder through self-organization. Semin. Cancer Biol. 21 165-174
    • (2011) Semin. Cancer Biol. , vol.21 , pp. 165-174
    • Saetzler, K.1    Sonnenschein, C.2    Soto, A.M.3
  • 127
    • 59649087503 scopus 로고    scopus 로고
    • Intrinsic disorder explains diverse nuclear roles of chromatin remodeling proteins
    • Sandhu KS 2009 Intrinsic disorder explains diverse nuclear roles of chromatin remodeling proteins. J. Mol. Recognit. 22 1-8
    • (2009) J. Mol. Recognit. , vol.22 , pp. 1-8
    • Sandhu, K.S.1
  • 129
    • 80051495448 scopus 로고    scopus 로고
    • Transcription factors that mediate epithelial-mesenchymal transition lead to multidrug resistance by upregulating ABC transporters
    • Saxena M, Stephens MA, Pathak H and Rangarajan A 2011 Transcription factors that mediate epithelial-mesenchymal transition lead to multidrug resistance by upregulating ABC transporters. Cell Death Dis. 2 e179
    • (2011) Cell Death Dis. , vol.2
    • Saxena, M.1    Stephens, M.A.2    Pathak, H.3    Rangarajan, A.4
  • 130
    • 80052964920 scopus 로고    scopus 로고
    • Phenotypic plasticity and epithelial-mesenchymal transitions in cancer and normal stem cells?
    • Scheel C and Weinberg RA 2011 Phenotypic plasticity and epithelial-mesenchymal transitions in cancer and normal stem cells? Int. J. Cancer 129 2310-2314
    • (2011) Int. J. Cancer , vol.129 , pp. 2310-2314
    • Scheel, C.1    Weinberg, R.A.2
  • 133
    • 4644219809 scopus 로고    scopus 로고
    • Cancer stem cells persist in many cancer cell lines
    • Setoguchi T, Taga T and Kondo T 2004 Cancer stem cells persist in many cancer cell lines. Cell Cycle 3 414-415 (Pubitemid 40278224)
    • (2004) Cell Cycle , vol.3 , Issue.4 , pp. 414-415
    • Setoguchi, T.1    Taga, T.2    Kondo, T.3
  • 134
    • 45649084243 scopus 로고    scopus 로고
    • Chaotic gene regulatory networks can be robust against mutations and noise
    • Sevim V and Rikvold PA 2008 Chaotic gene regulatory networks can be robust against mutations and noise. J. Theor. Biol. 253 323-332
    • (2008) J. Theor. Biol. , vol.253 , pp. 323-332
    • Sevim, V.1    Rikvold, P.A.2
  • 135
    • 84255204457 scopus 로고    scopus 로고
    • Prostate cancer and inflammation: The evidence
    • Sfanos KS and De Marzo AM 2012 Prostate cancer and inflammation: the evidence. Histopathology 60 199-215
    • (2012) Histopathology , vol.60 , pp. 199-215
    • Sfanos, K.S.1    De Marzo, A.M.2
  • 138
    • 1842581858 scopus 로고    scopus 로고
    • An error catastrophe in cancer?
    • DOI 10.1016/j.jtbi.2003.08.018, PII S0022519303004569
    • Sole RV and Deisboeck TS 2004 An error catastrophe in cancer? J. Theor. Biol. 228 47-54 (Pubitemid 38452725)
    • (2004) Journal of Theoretical Biology , vol.228 , Issue.1 , pp. 47-54
    • Sole, R.V.1    Deisboeck, T.S.2
  • 140
    • 84883205105 scopus 로고    scopus 로고
    • The aging of the 2000 and 2011 Hallmarks of Cancer reviews: A critique
    • Sonnenschein C and Soto AM 2013 The aging of the 2000 and 2011 Hallmarks of Cancer reviews: A critique. J. Biosci. 38 651-63
    • (2013) J. Biosci. , vol.38 , pp. 651-663
    • Sonnenschein, C.1    Soto, A.M.2
  • 141
    • 79954623572 scopus 로고    scopus 로고
    • The tissue organization field theory of cancer: A testable replacement for the somatic mutation theory
    • Soto AM and Sonnenschein C 2011 The tissue organization field theory of cancer: a testable replacement for the somatic mutation theory. BioEssays: News Rev. Mol. Cell. Dev. Biol. 33 332-40
    • (2011) BioEssays: News Rev. Mol. Cell. Dev. Biol. , vol.33 , pp. 332-340
    • Soto, A.M.1    Sonnenschein, C.2
  • 142
    • 84858726938 scopus 로고    scopus 로고
    • Is systems biology a promising approach to resolve controversies in cancer research?
    • Soto AM and Sonnenschein C 2012 Is systems biology a promising approach to resolve controversies in cancer research? Cancer Cell Int. 12 12
    • (2012) Cancer Cell Int. , vol.12 , pp. 12
    • Soto, A.M.1    Sonnenschein, C.2
  • 143
    • 84904176047 scopus 로고    scopus 로고
    • Paradoxes in carcinogenesis: There is light at the end of that tunnel!
    • Soto AM and Sonnenschein C 2013 Paradoxes in carcinogenesis: there is light at the end of that tunnel! Disrup. Sci. Technol. 1 154-156
    • (2013) Disrup. Sci. Technol. , vol.1 , pp. 154-156
    • Soto, A.M.1    Sonnenschein, C.2
  • 144
    • 57049112129 scopus 로고    scopus 로고
    • On physicalism and downward causation in developmental and cancer biology
    • Soto AM, Sonnenschein C and Miquel PA 2008 On physicalism and downward causation in developmental and cancer biology. Acta Biotheoretica 56 257-274
    • (2008) Acta Biotheoretica , vol.56 , pp. 257-274
    • Soto, A.M.1    Sonnenschein, C.2    Miquel, P.A.3
  • 146
    • 0001619450 scopus 로고
    • Growth and organized development of cultured cells. I. Growth and division freely suspended cells
    • Steward FC, Mapes MO and Smith J 1958 Growth and organized development of cultured cells. I. Growth and division freely suspended cells. Am. J. Bot. 45 693-703
    • (1958) Am. J. Bot. , vol.45 , pp. 693-703
    • Steward, F.C.1    Mapes, M.O.2    Smith, J.3
  • 148
    • 84875537133 scopus 로고    scopus 로고
    • Epigenetic reprogramming in cancer
    • Suva ML, Riggi N and Bernstein BE 2013 Epigenetic reprogramming in cancer. Science 339 1567-1570
    • (2013) Science , vol.339 , pp. 1567-1570
    • Suva, M.L.1    Riggi, N.2    Bernstein, B.E.3
  • 149
    • 84887456252 scopus 로고    scopus 로고
    • The epigenetics of epithelial-mesenchymal plasticity in cancer
    • Tam WL and Weinberg RA 2013 The epigenetics of epithelial-mesenchymal plasticity in cancer. Nat. Med. 19 1438-1449
    • (2013) Nat. Med. , vol.19 , pp. 1438-1449
    • Tam, W.L.1    Weinberg, R.A.2
  • 150
    • 2442619253 scopus 로고    scopus 로고
    • Colorectal cancer without high microsatellite instability and chromosomal instability - An alternative genetic pathway to human colorectal cancer
    • DOI 10.1093/carcin/bgh074
    • Tang R, Changchien CR, Wu MC, Fan CW, Liu KW, Chen JS, Chien HT and Hsieh LL 2004 Colorectal cancer without high microsatellite instability and chromosomal instability - an alternative genetic pathway to human colorectal cancer. Carcinogenesis 25 841-846 (Pubitemid 38618539)
    • (2004) Carcinogenesis , vol.25 , Issue.5 , pp. 841-846
    • Tang, R.1    Changchien, C.R.2    Wu, M.-C.3    Fan, C.-W.4    Liu, K.-W.5    Chen, J.-S.6    Chien, H.-T.7    Hsieh, L.-L.8
  • 152
    • 84881086323 scopus 로고    scopus 로고
    • Cancer as a dysregulated epigenome allowing cellular growth advantage at the expense of the host
    • Timp W and Feinberg AP 2013 Cancer as a dysregulated epigenome allowing cellular growth advantage at the expense of the host. Nat. Rev. Cancer 13 497-510
    • (2013) Nat. Rev. Cancer , vol.13 , pp. 497-510
    • Timp, W.1    Feinberg, A.P.2
  • 153
    • 3442902456 scopus 로고    scopus 로고
    • The role of structural disorder in the function of RNA and protein chaperones
    • DOI 10.1096/fj.04-1584rev
    • Tompa P and Csermely P 2004 The role of structural disorder in the function of RNA and protein chaperones. FASEB J. 18 1169-1175 (Pubitemid 39006878)
    • (2004) FASEB Journal , vol.18 , Issue.11 , pp. 1169-1175
    • Tompa, P.1    Csermely, P.2
  • 154
    • 84861512163 scopus 로고    scopus 로고
    • Intrinsically disordered proteins and novel strategies for drug discovery
    • Uversky VN 2012 Intrinsically disordered proteins and novel strategies for drug discovery. Expert Opin. Drug Discov. 7 475-488
    • (2012) Expert Opin. Drug Discov. , vol.7 , pp. 475-488
    • Uversky, V.N.1
  • 156
    • 0037169361 scopus 로고    scopus 로고
    • Cancer modeling in the modern era: Progress and challenges
    • DOI 10.1016/S0092-8674(02)00621-9
    • Van Dyke T and Jacks T 2002 Cancer modeling in the modern era: progress and challenges. Cell 108 135-144 (Pubitemid 34161134)
    • (2002) Cell , vol.108 , Issue.2 , pp. 135-144
    • Van Dyke, T.1    Jacks, T.2
  • 158
    • 79954575999 scopus 로고    scopus 로고
    • In defense of the somatic mutation theory of cancer
    • Vaux DL 2011 In defense of the somatic mutation theory of cancer. BioEssays: News Rev. Mol. Cell. Dev. Biol. 33 341-343
    • (2011) BioEssays: News Rev. Mol. Cell. Dev. Biol. , vol.33 , pp. 341-343
    • Vaux, D.L.1
  • 159
    • 67649635978 scopus 로고    scopus 로고
    • Intrinsic protein disorder and interaction promiscuity are widely associated with dosage sensitivity
    • Vavouri T, Semple JI, Garcia-Verdugo R and Lehner B 2009 Intrinsic protein disorder and interaction promiscuity are widely associated with dosage sensitivity. Cell 138 198-208
    • (2009) Cell , vol.138 , pp. 198-208
    • Vavouri, T.1    Semple, J.I.2    Garcia-Verdugo, R.3    Lehner, B.4
  • 160
    • 84864545633 scopus 로고    scopus 로고
    • Molecular link mechanisms between inflammation and cancer
    • Vendramini-Costa DB and Carvalho JE 2012 Molecular link mechanisms between inflammation and cancer. Curr. Pharm. Des. 18 3831-3852
    • (2012) Curr. Pharm. Des. , vol.18 , pp. 3831-3852
    • Vendramini-Costa, D.B.1    Carvalho, J.E.2
  • 161
    • 52549087785 scopus 로고    scopus 로고
    • Cancer stem cells in solid tumours: Accumulating evidence and unresolved questions
    • Visvader JE and Lindeman GJ 2008 Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat. Rev. Cancer 8 755-768
    • (2008) Nat. Rev. Cancer , vol.8 , pp. 755-768
    • Visvader, J.E.1    Lindeman, G.J.2
  • 162
    • 4043181214 scopus 로고    scopus 로고
    • Cancer genes and the pathways they control
    • DOI 10.1038/nm1087
    • Vogelstein B and Kinzler KW 2004 Cancer genes and the pathways they control. Nat. Med. 10 789-799 (Pubitemid 39070849)
    • (2004) Nature Medicine , vol.10 , Issue.8 , pp. 789-799
    • Vogelstein, B.1    Kinzler, K.W.2
  • 165
    • 51149203927 scopus 로고
    • Canalization of development and the inheritance of acquired characters
    • Waddington CH 1942 Canalization of development and the inheritance of acquired characters. Nature 150 563-565
    • (1942) Nature , vol.150 , pp. 563-565
    • Waddington, C.H.1
  • 166
    • 0038497542 scopus 로고
    • Molecular structure of nucleic acids; a structure for deoxyribose nucleic acid
    • Watson JD and Crick FH 1953 Molecular structure of nucleic acids; a structure for deoxyribose nucleic acid. Nature 171 737-738
    • (1953) Nature , vol.171 , pp. 737-738
    • Watson, J.D.1    Crick, F.H.2
  • 168
    • 36949065046 scopus 로고
    • Molecular structure of deoxypentose nucleic acids
    • Wilkins MH, Stokes AR and Wilson HR 1953 Molecular structure of deoxypentose nucleic acids. Nature 171 738-740
    • (1953) Nature , vol.171 , pp. 738-740
    • Wilkins, M.H.1    Stokes, A.R.2    Wilson, H.R.3
  • 169
    • 7644243641 scopus 로고    scopus 로고
    • The nature of stem cells: State rather than entity
    • DOI 10.1038/nrg1475
    • Zipori D 2004 The nature of stem cells: state rather than entity. Nat. Rev. Genet. 5 873-878 (Pubitemid 39457503)
    • (2004) Nature Reviews Genetics , vol.5 , Issue.11 , pp. 873-878
    • Zipori, D.1


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