Assessment of differences in the conformational flexibility of hepatitis B virus core-antigen and e-antigen by hydrogen deuterium exchange-mass spectrometry

Protein Science

Volumn 23, Issue 7, 2014, Pages 884-896

  Bereszczak, Jessica Z ^a,b   Watts, Norman R ^c   Wingfield, Paul T ^c   Steven, Alasdair C ^c   Heck, Albert J R ^a,b  

^a UTRECHT UNIVERSITY   (Netherlands)

^b NETHERLANDS PROTEOMICS CENTRE   (Netherlands)

^c NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

Author keywords

E antigen; EX1 kinetics; Hepatitis B virus; Hydrogen deuterium exchange mass spectrometry

Indexed keywords

DIMER; DISULFIDE; HEPATITIS B CORE ANTIGEN; HEPATITIS E ANTIGEN; IMMUNOGLOBULIN F(AB) FRAGMENT; HEPATITIS B(E) ANTIGEN;

ANTIGEN BINDING; ANTIGEN DETECTION; ANTIGEN STRUCTURE; ANTIGENICITY; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DEUTERIUM HYDROGEN EXCHANGE; DISULFIDE BOND; IMMUNOREGULATION; MASS SPECTROMETRY; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION; REDUCTION KINETICS; VIRUS CAPSID; CHEMISTRY; HEPATITIS B VIRUS; KINETICS; METABOLISM; PROCEDURES; PROTEIN MULTIMERIZATION; PROTEIN QUATERNARY STRUCTURE;

DEUTERIUM EXCHANGE MEASUREMENT; HEPATITIS B CORE ANTIGENS; HEPATITIS B E ANTIGENS; HEPATITIS B VIRUS; IMMUNOGLOBULIN FAB FRAGMENTS; KINETICS; MASS SPECTROMETRY; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY;

EID: 84904171369     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1002/pro.2470     Document Type: Article

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