Thermodynamic origins of protein folding, allostery, and capsid formation in the human hepatitis B virus core protein

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 30, 2013, Pages

  Alexander, Crispin G ^a   Jurgens, Maike C ^a   Shepherd, Dale A ^b   Freund, Stefan M V ^c   Ashcroft, Alison E ^b   Ferguson, Neil ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

^b UNIVERSITY OF LEEDS   (United Kingdom)

^c MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

Capsid assembly; Energy landscape; Protein dynamics; Thermodynamic coupling

Indexed keywords

CORE PROTEIN; DIMER; MUTANT PROTEIN;

ALLOSTERISM; ALPHA HELIX; ANALYTIC METHOD; ARTICLE; CONFORMATIONAL TRANSITION; HEPATITIS B VIRUS; ION MOBILITY SPECTROMETRY; MASS SPECTROMETRY; MICROSCALE THERMOPHORESIS; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN ENGINEERING; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN STABILITY; PROTEIN STRUCTURE; THERMODYNAMICS; VIRUS CAPSID; VIRUS REPLICATION;

CAPSID ASSEMBLY; ENERGY LANDSCAPE; PROTEIN DYNAMICS; THERMODYNAMIC COUPLING;

ALLOSTERIC REGULATION; CAPSID; DIMERIZATION; HEPATITIS B VIRUS; MASS SPECTROMETRY; MODELS, MOLECULAR; PROTEIN FOLDING; THERMODYNAMICS; VIRAL CORE PROTEINS;

EID: 84880691749     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1308846110     Document Type: Article

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