Chimpanzee/human mAbs to vaccinia virus B5 protein neutralize vaccinia and smallpox viruses and protect mice against vaccinia virus

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 6, 2006, Pages 1882-1887

  Chen, Zhaochun ^a   Earl, Patricia ^b   Americo, Jeffrey ^b   Damon, Inger ^c   Smith, Scott K ^c   Zhou, Yi Hua ^a   Yu, Fujuan ^a   Sebrell, Andrew ^a   Emerson, Suzanne ^a   Cohen, Gary ^d   Eisenberg, Roselyn J ^d   Svitel, Juraj ^a   Schuck, Peter ^a   Satterfield, William ^e   Moss, Bernard ^b   Purcell, Robert ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Biodefense

Indexed keywords

EPITOPE; GLYCOPROTEIN; IMMUNOGLOBULIN; IMMUNOGLOBULIN F(AB) FRAGMENT; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 19C2; MONOCLONAL ANTIBODY 8AH7AL; MONOCLONAL ANTIBODY 8AH8AL; MONOCLONAL ANTIBODY VACCINIA VIRUS B5 PROTEIN; SMALLPOX VACCINE; UNCLASSIFIED DRUG; VACCINIA VACCINE; VACCINIA VIRUS B5 PROTEIN; VIRUS PROTEIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; CHIMPANZEE; CONTROLLED STUDY; DRUG PROTEIN BINDING; FEMALE; HEAVY CHAIN; HUMAN; IMMUNOPROPHYLAXIS; IMMUNOTHERAPY; IN VITRO STUDY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ISOLATION; RAT; SMALLPOX; SMALLPOX VIRUS; STATISTICAL SIGNIFICANCE; VACCINATION REACTION; VACCINIA; VACCINIA VIRUS; VIRUS ENVELOPE; VIRUS INHIBITION; VIRUS NEUTRALIZATION; VIRUS VIRULENCE;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; EPITOPES; FEMALE; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; MICE; MOLECULAR SEQUENCE DATA; NEUTRALIZATION TESTS; PAN TROGLODYTES; VACCINIA; VACCINIA VIRUS; VARIOLA VIRUS; VIRAL PROTEINS;

ANIMALIA; PAN TROGLODYTES; VACCINIA VIRUS; VARIOLA VIRUS;

EID: 32444440977     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0510598103     Document Type: Article

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