-
1
-
-
67649205803
-
The potential for nanoparticle-based drug delivery to the brain: Overcoming the blood-brain barrier
-
Barbu, E.; Molnàr, E.; Tsibouklis, J.; Górecki, D.C. The potential for nanoparticle-based drug delivery to the brain: overcoming the blood-brain barrier. Expert Opin. Drug Deliv., 2009, 6, 553-565.
-
(2009)
Expert Opin. Drug Deliv
, vol.6
, pp. 553-565
-
-
Barbu, E.1
Molnàr, E.2
Tsibouklis, J.3
Górecki, D.C.4
-
2
-
-
0034032642
-
Cell replacement therapies for central nervous system disorders
-
Björklund, A.; Lindvall, O. Cell replacement therapies for central nervous system disorders. Nat. Neurosci., 2000, 3, 537-544.
-
(2000)
Nat. Neurosci
, vol.3
, pp. 537-544
-
-
Björklund, A.1
Lindvall, O.2
-
3
-
-
84875443169
-
Long-term expression and safety of administration of AAVrh.10hCLN2 to the brain of rats and nonhuman primates for the treatment of late infantile neuronal ceroid lipofuscinosis
-
Sondhi, D.; Johnson, L.; Purpura, K.; Monette, S.; Souweidane, M.M.; Kaplitt, M.G.; Kosofsky, B.; Yohay, K.; Ballon, D.; Dyke, J.; Kaminksy, S.M.; Hackett, N.R.; Crystal, R.G. Long-term expression and safety of administration of AAVrh.10hCLN2 to the brain of rats and nonhuman primates for the treatment of late infantile neuronal ceroid lipofuscinosis. Hum. Gene Ther. Methods, 2012, 23, 324-335.
-
(2012)
Hum. Gene Ther. Methods
, vol.23
, pp. 324-335
-
-
Sondhi, D.1
Johnson, L.2
Purpura, K.3
Monette, S.4
Souweidane, M.M.5
Kaplitt, M.G.6
Kosofsky, B.7
Yohay, K.8
Ballon, D.9
Dyke, J.10
Kaminksy, S.M.11
Hackett, N.R.12
Crystal, R.G.13
-
4
-
-
33645861655
-
Gene therapy for lysosomal storage diseases
-
Sands, M.S.; Davidson, B.L. Gene therapy for lysosomal storage diseases. Mol. Ther., 2006, 13, 839-849.
-
(2006)
Mol. Ther
, vol.13
, pp. 839-849
-
-
Sands, M.S.1
Davidson, B.L.2
-
5
-
-
41049095852
-
CNS-directed gene therapy for lysosomal storage disease
-
Sands, M.S.; Haskins, M.E. CNS-directed gene therapy for lysosomal storage disease. Acta Paediatr., 2008, 97, 22-27.
-
(2008)
Acta Paediatr
, vol.97
, pp. 22-27
-
-
Sands, M.S.1
Haskins, M.E.2
-
6
-
-
79960874985
-
Strategies for enhancing antibody delivery to the brain
-
Frank, R.T.; Aboody, K. S.; Najbauer, J. Strategies for enhancing antibody delivery to the brain. Biochim. Biophys. Acta, 2011, 1816, 191-198.
-
(2011)
Biochim. Biophys. Acta
, vol.1816
, pp. 191-198
-
-
Frank, R.T.1
Aboody, K.S.2
Najbauer, J.3
-
7
-
-
23444437213
-
Convection-enhanced delivery of macromole-cules in the brain
-
Bobo, R.H.; Laske, D.W.; Akbasak, A.; Morrison, P.F.; Dedrick, R.L.; Oldfield, E.H. Convection-enhanced delivery of macromole-cules in the brain. Proc. Natl. Acad. Sci. U. S. A, 1994, 91, 2076-2080.
-
(1994)
Proc. Natl. Acad. Sci. U. S. A
, vol.91
, pp. 2076-2080
-
-
Bobo, R.H.1
Laske, D.W.2
Akbasak, A.3
Morrison, P.F.4
Dedrick, R.L.5
Oldfield, E.H.6
-
8
-
-
33847240102
-
Im-plantable intrathecal pumps for chronic pain: Highlights and updates
-
Knight, K.H.; Brand, F.M.; Mchaourab, A.S.; Veneziano, G. Im-plantable intrathecal pumps for chronic pain: highlights and updates. Croat. Med. J., 2007, 48, 22-34.
-
(2007)
Croat. Med. J
, vol.48
, pp. 22-34
-
-
Knight, K.H.1
Brand, F.M.2
McHaourab, A.S.3
Veneziano, G.4
-
9
-
-
0029095850
-
Catheter implant systems for intrathecal drug delivery
-
Penn, R.D.; York, M.M.; Paice, J.A. Catheter implant systems for intrathecal drug delivery. J. Neurosurg., 1995, 83, 215-217.
-
(1995)
J. Neurosurg
, vol.83
, pp. 215-217
-
-
Penn, R.D.1
York, M.M.2
Paice, J.A.3
-
10
-
-
57449105820
-
Pathways for Drug Delivery to the Central Nervous System
-
Wang, B.; Siahaan, T.; Soltero, R., Eds.; John Wiley & Sons, Inc
-
Zhang, Y.; Miler, D.W. Pathways for Drug Delivery to the Central Nervous System. In Drug Delivery: Principles and Applications; Wang, B.; Siahaan, T.; Soltero, R., Eds.; John Wiley & Sons, Inc., 2005; pp. 29-53.
-
(2005)
Drug Delivery: Principles and Applications
, pp. 29-53
-
-
Zhang, Y.1
Miler, D.W.2
-
11
-
-
77949833508
-
Intranasal Delivery to the Central Nervous System: Mechanisms and Experimental Considerations
-
Dhuria, S.V; Hanson, L.R.; Frey II, W.H. Intranasal Delivery to the Central Nervous System: Mechanisms and Experimental Considerations. J. Pharm. Sci., 2010, 99, 1654-1673.
-
(2010)
J. Pharm. Sci
, vol.99
, pp. 1654-1673
-
-
Dhuria, S.V.1
Hanson, L.R.2
Frey, I.I.3
-
12
-
-
84860193946
-
Intranasal delivery of biologics to the central nervous system
-
Lochhead, J.J.; Thorne, R.G. Intranasal delivery of biologics to the central nervous system. Adv. Drug Deliv. Rev., 2012, 64, 614-628.
-
(2012)
Adv. Drug Deliv. Rev
, vol.64
, pp. 614-628
-
-
Lochhead, J.J.1
Thorne, R.G.2
-
13
-
-
84860342240
-
A new method of quantitatively assessing the opening of the blood-brain barrier in murine animal models
-
Blanchette, M.; Michaud, K.; Fortin, D. A new method of quantitatively assessing the opening of the blood-brain barrier in murine animal models. J. Neurosci. Methods, 2012, 207, 125-129.
-
(2012)
J. Neurosci. Methods
, vol.207
, pp. 125-129
-
-
Blanchette, M.1
Michaud, K.2
Fortin, D.3
-
14
-
-
77953473441
-
Novel and emerging strategies in drug delivery for overcoming the blood-brain barrier
-
Stenehjem, D.D.; Hartz, A.M.S.; Bauer, B.; Anderson, G.W. Novel and emerging strategies in drug delivery for overcoming the blood-brain barrier. Future Med. Chem., 2009, 1, 1623-1641.
-
(2009)
Future Med. Chem
, vol.1
, pp. 1623-1641
-
-
Stenehjem, D.D.1
Hartz, A.M.S.2
Bauer, B.3
Anderson, G.W.4
-
15
-
-
2342471420
-
The blood-brain barrier: An overview: Structure, regulation, and clinical implications
-
Ballabh, P.; Braun, A.; Nedergaard, M. The blood-brain barrier: an overview: structure, regulation, and clinical implications. Neuro-biol. Dis., 2004, 16, 1-13.
-
(2004)
Neuro-biol. Dis
, vol.16
, pp. 1-13
-
-
Ballabh, P.1
Braun, A.2
Nedergaard, M.3
-
16
-
-
29244463365
-
Astrocyte-endothelial interactions at the blood-brain barrier
-
Abbott, N.J.; Rönnbäck, L.; Hansson, E. Astrocyte-endothelial interactions at the blood-brain barrier. Nat. Rev. Neurosci., 2006, 7, 41-53.
-
(2006)
Nat. Rev. Neurosci
, vol.7
, pp. 41-53
-
-
Abbott, N.J.1
Rönnbäck, L.2
Hansson, E.3
-
17
-
-
0037120667
-
Local drug delivery to the brain
-
Wang, P.P.; Frazier, J.; Brem, H. Local drug delivery to the brain. Adv. Drug Deliv. Rev., 2002, 54, 987-1013.
-
(2002)
Adv. Drug Deliv. Rev
, vol.54
, pp. 987-1013
-
-
Wang, P.P.1
Frazier, J.2
Brem, H.3
-
18
-
-
70449529433
-
Structure and function of the blood-brain barrier
-
Abbott, N.J.; Patabendige, A. a K.; Dolman, D.E.M.; Yusof, S.R.; Begley, D.J. Structure and function of the blood-brain barrier. Neu-robiol. Dis., 2010, 37, 13-25.
-
(2010)
Neu-robiol. Dis
, vol.37
, pp. 13-25
-
-
Abbott, N.J.1
Patabendige, A.A.K.2
Dolman, D.E.M.3
Yusof, S.R.4
Begley, D.J.5
-
19
-
-
0033974507
-
Osmotic opening of the blood-brain barrier: Principles, mechanism, and therapeutic applications
-
Rapoport, S.I. Osmotic opening of the blood-brain barrier: principles, mechanism, and therapeutic applications. Cell. Mol. Neuro-biol., 2000, 20, 217-230.
-
(2000)
Cell. Mol. Neuro-biol
, vol.20
, pp. 217-230
-
-
Rapoport, S.I.1
-
21
-
-
0022559194
-
Specialized Properties and Solute Transport in Brain Capillaries
-
Betz, A.L.; Goldstein, G.W. Specialized Properties and Solute Transport in Brain Capillaries. Ann. Rev. Physiol., 1986, 48, 241-250.
-
(1986)
Ann. Rev. Physiol
, vol.48
, pp. 241-250
-
-
Betz, A.L.1
Goldstein, G.W.2
-
22
-
-
84903729296
-
-
M, N. Y. D. D
-
D.D.; Silvestrini, B.; Cheng, C.Y.A.N.; Council, P.; York, N.; M, N. Y. D. D. Anchoring Junctions As Drug Targets: 2008, 60, 146-180.
-
(2008)
Anchoring Junctions As Drug Targets
, vol.60
, pp. 146-180
-
-
-
23
-
-
0016724876
-
Segmental Differentiations of Cell Junctions in the Vascular Endothelium: The Mi-crovasculature
-
Simionescu, M.; Simionescu, N.; Palade, G.E. Segmental Differentiations of Cell Junctions in the Vascular Endothelium: The Mi-crovasculature. J. Cell Biol., 1975, 67, 863-885.
-
(1975)
J. Cell Biol
, vol.67
, pp. 863-885
-
-
Simionescu, M.1
Simionescu, N.2
Palade, G.E.3
-
24
-
-
0003880161
-
-
4th ed.; Garland Science: New York
-
Alberts, B.; Johnson, A.; Lewis, J.; Raff, M.; Roberts, K.; Walker, P. Molecular Biology of the Cell; 4th ed.; Garland Science: New York, 2002.
-
(2002)
Molecular Biology of the Cell
-
-
Alberts, B.1
Johnson, A.2
Lewis, J.3
Raff, M.4
Roberts, K.5
Walker, P.6
-
25
-
-
0029841675
-
Gap Junctions in Vascular Tissues
-
Christ, G.J.; Spray, D.C.; El-Sabban, M.; Moore, L.K.; Brink, P.R. Gap Junctions in Vascular Tissues. Circ. Res., 1996, 631-646.
-
(1996)
Circ. Res
, pp. 631-646
-
-
Christ, G.J.1
Spray, D.C.2
El-Sabban, M.3
Moore, L.K.4
Brink, P.R.5
-
27
-
-
0030270961
-
Pericytes in the microvasculature
-
Hirschi, K.K.; D'Amore, P.A., Pericytes in the microvasculature. Cardiovasc. Res., 1996, 32, 687-698.
-
(1996)
Cardiovasc. Res
, vol.32
, pp. 687-698
-
-
Hirschi, K.K.1
D'Amore, P.A.2
-
28
-
-
78649467527
-
Pericytes regulate the blood-brain barrier
-
Armulik, A.; Genové, G.; Mäe, M.; Nisancioglu, M.H.; Wallgard, E.; Niaudet, C.; He, L.; Norlin, J.; Lindblom, P.; Strittmatter, K.; Johansson, B.R.; Betsholtz, C. Pericytes regulate the blood-brain barrier. Nature, 2010, 468, 557-561.
-
(2010)
Nature
, vol.468
, pp. 557-561
-
-
Armulik, A.1
Genové, G.2
Mäe, M.3
Nisancioglu, M.H.4
Wallgard, E.5
Niaudet, C.6
He, L.7
Norlin, J.8
Lindblom, P.9
Strittmatter, K.10
Johansson, B.R.11
Betsholtz, C.12
-
29
-
-
84886094687
-
Blood-Brain Barrier In Vitro: Rapid Evaluation of Strategies for Achieving Drug Targeting to the Central Nervous System
-
Couraud, P.-O.; Scherman, D., Eds.; Plenum Press: New York
-
Dehouck, M.P.; Dehouck, B.; Fenart, L.; Cecchelli, R. Blood-Brain Barrier In Vitro: Rapid Evaluation of Strategies for Achieving Drug Targeting to the Central Nervous System. In Biology and Physiology of the Blood-Brain Barrier: Transport, Cellular Interactions, and Brain Pathologies; Couraud, P.-O.; Scherman, D., Eds.; Plenum Press: New York, 1996; pp. 143-145.
-
(1996)
Biology and Physiology of the Blood-Brain Barrier: Transport, Cellular Interactions, and Brain Pathologies
, pp. 143-145
-
-
Dehouck, M.P.1
Dehouck, B.2
Fenart, L.3
Cecchelli, R.4
-
30
-
-
84869498477
-
Challenges in drug delivery to the brain: Nature is against us
-
Krol, S. Challenges in drug delivery to the brain: nature is against us. J. Control. Release, 2012, 164, 145-155.
-
(2012)
J. Control. Release
, vol.164
, pp. 145-155
-
-
Krol, S.1
-
31
-
-
0345159498
-
The Microarchitecture of Cerebral Vessels
-
Couraud, P.-O.; Scherman, D., Eds.; Plenum Press: New York
-
Davies, K.R.; Richardson, G.; Akmentin, W.; Acuff, V.; Fenster-macher, J.D. The Microarchitecture of Cerebral Vessels. In Biology and Physiology of the Blood-Brain Barrier: Transport, Cellular Interactions, and Brain Pathologies1; Couraud, P.-O.; Scherman, D., Eds.; Plenum Press: New York, 1996; pp. 83-90.
-
(1996)
Biology and Physiology of the Blood-Brain Barrier: Transport, Cellular Interactions, and Brain Pathologies1
, pp. 83-90
-
-
Davies, K.R.1
Richardson, G.2
Akmentin, W.3
Acuff, V.4
Fenster-Macher, J.D.5
-
33
-
-
0003632424
-
Blood-brain barrier transport of drugs
-
Pardridge, W. M., Ed.; Cambridge University Press
-
Tsuji, A.; Tamai, I. Blood-brain barrier transport of drugs. In Introduction to the Blood-Brain Barrier: Methodology, Biology, and Pa-thology2; Pardridge, W. M., Ed.; Cambridge University Press, 2006; pp. 238-245.
-
(2006)
Introduction to The Blood-Brain Barrier: Methodology, Biology, and Pa-thology2
, pp. 238-245
-
-
Tsuji, A.1
Tamai, I.2
-
34
-
-
0035960650
-
The cerebrospinal fluid production rate is reduced in dementia of the Alzheimer's type
-
Silverberg, G.D.; Heit, G.; Huhn, S.; Jaffe, R.A.; Chang, S.D.; Bronte-Stewart, H.; Rubenstein, E.; Possin, K.; Saul, T.A. The cerebrospinal fluid production rate is reduced in dementia of the Alzheimer's type. Neurology, 2001, 57, 1763-1766.
-
(2001)
Neurology
, vol.57
, pp. 1763-1766
-
-
Silverberg, G.D.1
Heit, G.2
Huhn, S.3
Jaffe, R.A.4
Chang, S.D.5
Bronte-Stewart, H.6
Rubenstein, E.7
Possin, K.8
Saul, T.A.9
-
35
-
-
0037526444
-
Development of the brain: A vital role for cerebrospinal fluid
-
Miyan, J.A.; Nabiyouni, M.; Zendah, M. Development of the brain: a vital role for cerebrospinal fluid. Can. J. Physoilogy Pharmacol., 2003, 81, 317-328.
-
(2003)
Can. J. Physoilogy Pharmacol
, vol.81
, pp. 317-328
-
-
Miyan, J.A.1
Nabiyouni, M.2
Zendah, M.3
-
36
-
-
0000583211
-
Blood-Cerebrospinal Fluid Barrier
-
Lippincott-Raven: Philadelphia
-
Laterra, J.; Keep, R.; Betz, L.A.; Goldstein, G.W. Blood-Cerebrospinal Fluid Barrier. In Basic Neurochemistry: Molecular, Cellular and Medical Aspects; Lippincott-Raven: Philadelphia, 1999.
-
(1999)
Basic Neurochemistry: Molecular, Cellular and Medical Aspects
-
-
Laterra, J.1
Keep, R.2
Betz, L.A.3
Goldstein, G.W.4
-
37
-
-
0032890649
-
Brief Review: Barrier Mechanisms in the Brain, I. Adult Brain
-
Saunders, N.R.; Dziegielewska, K.M. Brief Review: Barrier Mechanisms in the Brain, I. Adult Brain. Clin. Exp. Pharmacol. Physiol., 1998, 26, 11-19.
-
(1998)
Clin. Exp. Pharmacol. Physiol
, vol.26
, pp. 11-19
-
-
Saunders, N.R.1
Dziegielewska, K.M.2
-
38
-
-
76749146826
-
The regulation of brain states by neuroactive substances distributed via the cerebrospinal fluid; a review
-
Veening, J.G.; Barendregt, H.P. The regulation of brain states by neuroactive substances distributed via the cerebrospinal fluid; a review. Cerebrospinal Fluid Res., 2010, 7, 1.
-
(2010)
Cerebrospinal Fluid Res
, vol.7
, pp. 1
-
-
Veening, J.G.1
Barendregt, H.P.2
-
39
-
-
0000583211
-
Blood-Cerebrospinal Fluid Barrier
-
Lippincott-Raven: Philadelphia
-
Laterra, J.; Keep, R.; Betz, L.A.; Goldstein, G.W. Blood-Cerebrospinal Fluid Barrier. In Basic Neurochemistry: Molecular, Cellular and Medical Aspects; Lippincott-Raven: Philadelphia, 1999.
-
(1999)
Basic Neurochemistry: Molecular, Cellular and Medical Aspects
-
-
Laterra, J.1
Keep, R.2
Betz, L.A.3
Goldstein, G.W.4
-
40
-
-
84864540429
-
Gene transfer corrects acute GM2 gangliosidosis--potential therapeutic contribution of perivascular enzyme flow
-
Cachón-González, M.B.; Wang, S.Z.; McNair, R.; Bradley, J.; Lunn, D.; Ziegler, R.; Cheng, S.H.; Cox, T.M. Gene transfer corrects acute GM2 gangliosidosis--potential therapeutic contribution of perivascular enzyme flow. Mol. Ther., 2012, 20, 1489-1500.
-
(2012)
Mol. Ther
, vol.20
, pp. 1489-1500
-
-
Cachón-González, M.B.1
Wang, S.Z.2
McNair, R.3
Bradley, J.4
Lunn, D.5
Ziegler, R.6
Cheng, S.H.7
Cox, T.M.8
-
41
-
-
78149463784
-
AAV-mediated gene delivery in adult GM1-gangliosidosis mice corrects lysosomal storage in CNS and improves survival
-
Baek, R.C.; Broekman, M.L.D.; Leroy, S.G.; Tierney, L. A; Sand-berg, M. A; D'Azzo, A.; Seyfried, T. N.; Sena-Esteves, M. AAV-mediated gene delivery in adult GM1-gangliosidosis mice corrects lysosomal storage in CNS and improves survival. PLoS One, 2010, 5, e13468.
-
(2010)
PLoS One
, vol.5
-
-
Baek, R.C.1
Broekman, M.L.D.2
Leroy, S.G.3
Tierney, L.A.4
Sand-Berg, M.A.5
D'Azzo, A.6
Seyfried, T.N.7
Sena-Esteves, M.8
-
42
-
-
60849128839
-
Convection-enhanced delivery of nanocarriers for the treatment of brain tumors
-
Allard, E.; Passirani, C.; Benoit, J.-P. Convection-enhanced delivery of nanocarriers for the treatment of brain tumors. Biomaterials, 2009, 30, 2302-2318.
-
(2009)
Biomaterials
, vol.30
, pp. 2302-2318
-
-
Allard, E.1
Passirani, C.2
Benoit, J.-P.3
-
44
-
-
0034023168
-
A prospective study of catheter-related complications of intrathecal drug delivery systems
-
Follett, K. A; Naumann, C.P. A prospective study of catheter-related complications of intrathecal drug delivery systems. J. Pain Symptom Manage., 2000, 19, 209-215.
-
(2000)
J. Pain Symptom Manage
, vol.19
, pp. 209-215
-
-
Follett, K.A.1
Naumann, C.P.2
-
45
-
-
29244472029
-
Barriers to carrier mediated drug and gene delivery to brain tumors
-
Huynh, G.H.; Deen, D.F.; Szoka, F.C. Barriers to carrier mediated drug and gene delivery to brain tumors. J. Control. Release, 2006, 110, 236-259.
-
(2006)
J. Control. Release
, vol.110
, pp. 236-259
-
-
Huynh, G.H.1
Deen, D.F.2
Szoka, F.C.3
-
46
-
-
33845784758
-
Blood-brain barrier delivery
-
Pardridge, W.M. Blood-brain barrier delivery. Drug Discov. Today, 2007, 12, 54-61.
-
(2007)
Drug Discov. Today
, vol.12
, pp. 54-61
-
-
Pardridge, W.M.1
-
47
-
-
84863978211
-
Receptor-Mediated Drug Delivery
-
Wang, B.; Siahaan, T.; Soltero, R., Eds.; John Wiley & Sons, Inc
-
Leamon, C.P. Receptor-Mediated Drug Delivery. In Drug Delivery: Principles and Applications; Wang, B.; Siahaan, T.; Soltero, R., Eds.; John Wiley & Sons, Inc., 2005; pp. 167-185.
-
(2005)
Drug Delivery: Principles and Applications
, pp. 167-185
-
-
Leamon, C.P.1
-
49
-
-
70449529637
-
Approaches to transport therapeutic drugs across the blood-brain barrier to treat brain diseases
-
Gabathuler, R. Approaches to transport therapeutic drugs across the blood-brain barrier to treat brain diseases. Neurobiol. Dis., 2010, 37, 48-57.
-
(2010)
Neurobiol. Dis
, vol.37
, pp. 48-57
-
-
Gabathuler, R.1
-
50
-
-
79958706127
-
Transferrin mediated drug delivery to brain
-
Chandra, D.; Karande, P. Transferrin mediated drug delivery to brain. Bioeng. Conf., 2011, 1-2.
-
(2011)
Bioeng. Conf
, pp. 1-2
-
-
Chandra, D.1
Karande, P.2
-
51
-
-
84868573143
-
Drug transport across the blood-brain barrier
-
Pardridge, W.M. Drug transport across the blood-brain barrier. J. Cereb. Blood Flow Metab., 2012, 32, 1959-1972.
-
(2012)
J. Cereb. Blood Flow Metab
, vol.32
, pp. 1959-1972
-
-
Pardridge, W.M.1
-
52
-
-
0033996507
-
Transport Across the Primate Blood- Brain Barrier of a Genetically Engineered Chimeric Monoclonal Antibody to the Human Insulin Receptor
-
Coloma, M.J.; Lee, H.J.; Kurihara, A.; Landaw, E.M.; Boado, R.J.; Morrison, S.L.; Pardridge, W.M. Transport Across the Primate Blood- Brain Barrier of a Genetically Engineered Chimeric Monoclonal Antibody to the Human Insulin Receptor. Pharm. Res., 2000, 17, 266-274.
-
(2000)
Pharm. Res
, vol.17
, pp. 266-274
-
-
Coloma, M.J.1
Lee, H.J.2
Kurihara, A.3
Landaw, E.M.4
Boado, R.J.5
Morrison, S.L.6
Pardridge, W.M.7
-
53
-
-
33846897981
-
Humanization of Anti-Human Insulin Receptor Antibody for Drug Targeting Across the Human
-
Boado, R.J.; Zhang, Y.; Zhang, Y.; Pardridge, W.M. Humanization of Anti-Human Insulin Receptor Antibody for Drug Targeting Across the Human. Biotechnol. Bioeng., 2007, 96, 381-391.
-
(2007)
Biotechnol. Bioeng
, vol.96
, pp. 381-391
-
-
Boado, R.J.1
Zhang, Y.2
Zhang, Y.3
Pardridge, W.M.4
-
54
-
-
84855597543
-
Reengineering biopharmaceuticals for targeted delivery across the blood-brain barrier
-
Pardridge, W.M.; Boado, R.J. Reengineering biopharmaceuticals for targeted delivery across the blood-brain barrier. Methods in En-zymology, 2012, 503, 269-292.
-
(2012)
Methods In En-zymology
, vol.503
, pp. 269-292
-
-
Pardridge, W.M.1
Boado, R.J.2
-
55
-
-
44449128659
-
GDNF fusion protein for targeted-drug delivery across the human blood-brain barrier
-
Boado, R.J.; Zhang, Y.; Zhang, Y.; Wang, Y.; Pardridge, W.M. GDNF fusion protein for targeted-drug delivery across the human blood-brain barrier. Biotechnol. Bioeng., 2008, 100, 387-396.
-
(2008)
Biotechnol. Bioeng
, vol.100
, pp. 387-396
-
-
Boado, R.J.1
Zhang, Y.2
Zhang, Y.3
Wang, Y.4
Pardridge, W.M.5
-
56
-
-
84874271571
-
Engineering a lysosomal enzyme with a derivative of receptor-binding domain of apoE enables delivery across the blood-brain barrier
-
Wang, D.; El-Amouri, S.S.; Dai, M.; Kuan, C.-Y.; Hui, D.Y.; Brady, R.O.; Pan, D. Engineering a lysosomal enzyme with a derivative of receptor-binding domain of apoE enables delivery across the blood-brain barrier. Proc. Natl. Acad. Sci. U. S. A, 2013, 110, 2999-3004.
-
(2013)
Proc. Natl. Acad. Sci. U. S. A
, vol.110
, pp. 2999-3004
-
-
Wang, D.1
El-Amouri, S.S.2
Dai, M.3
Kuan, C.-Y.4
Hui, D.Y.5
Brady, R.O.6
Pan, D.7
-
57
-
-
84877596293
-
A highly secreted sulphamidase engineered to cross the blood-brain barrier corrects brain lesions of mice with mucopolysaccharidoses type IIIA
-
Sorrentino, N.C.; D'Orsi, L.; Sambri, I.; Nusco, E.; Monaco, C.; Spampanato, C.; Polishchuk, E.; Saccone, P.; De Leonibus, E.; Bal-labio, A.; Fraldi, A. A highly secreted sulphamidase engineered to cross the blood-brain barrier corrects brain lesions of mice with mucopolysaccharidoses type IIIA. EMBO Mol. Med., 2013, 5(5), 675-690.
-
(2013)
EMBO Mol. Med
, vol.5
, Issue.5
, pp. 675-690
-
-
Sorrentino, N.C.1
D'Orsi, L.2
Sambri, I.3
Nusco, E.4
Monaco, C.5
Spampanato, C.6
Polishchuk, E.7
Saccone, P.8
de Leonibus, E.9
Bal-Labio, A.10
Fraldi, A.11
-
58
-
-
34548650086
-
Blood-brain barrier delivery of protein and non-viral gene therapeutics with molecular Trojan horses
-
Pardridge, W.M. Blood-brain barrier delivery of protein and non-viral gene therapeutics with molecular Trojan horses. J. Control. Release, 2007, 122, 345-348.
-
(2007)
J. Control. Release
, vol.122
, pp. 345-348
-
-
Pardridge, W.M.1
-
59
-
-
58549114669
-
Liposome encapsulated polyethylenimine/ODN polyplexes for brain targeting
-
Ko, Y.T.; Bhattacharya, R.; Bickel, U. Liposome encapsulated polyethylenimine/ODN polyplexes for brain targeting. J. Control. Release, 2009, 133, 230-237.
-
(2009)
J. Control. Release
, vol.133
, pp. 230-237
-
-
Ko, Y.T.1
Bhattacharya, R.2
Bickel, U.3
-
60
-
-
1342332987
-
Gene Targeting In Vivo with Pegylated Immu-noliposomes
-
Pardridge, W.M. Gene Targeting In Vivo with Pegylated Immu-noliposomes. Methods Enzymol., 2003, 373, 507-528.
-
(2003)
Methods Enzymol
, vol.373
, pp. 507-528
-
-
Pardridge, W.M.1
-
61
-
-
8744266243
-
Efficient transfer of receptor-associated protein (RAP) across the blood-brain barrier
-
Pan, W.; Kastin, A.J.; Zankel, T.C.; van Kerkhof, P.; Terasaki, T.; Bu, G. Efficient transfer of receptor-associated protein (RAP) across the blood-brain barrier. J. Cell Sci., 2004, 117, 5071-5078.
-
(2004)
J. Cell Sci
, vol.117
, pp. 5071-5078
-
-
Pan, W.1
Kastin, A.J.2
Zankel, T.C.3
van Kerkhof, P.4
Terasaki, T.5
Bu, G.6
-
62
-
-
51249091226
-
Recent advances in blood-brain barrier disruption as a CNS delivery strategy
-
Bellavance, M.-A.; Blanchette, M.; Fortin, D. Recent advances in blood-brain barrier disruption as a CNS delivery strategy. AAPS J., 2008, 10, 166-177.
-
(2008)
AAPS J
, vol.10
, pp. 166-177
-
-
Bellavance, M.-A.1
Blanchette, M.2
Fortin, D.3
-
63
-
-
79953711501
-
Chapter 23: Blood-Brain Barrier Disruption in the Treatment of Brain Tumors
-
Nag, S., Ed.; Humana Press: Totowa, NJ
-
Blanchette, M.; Fortin, D. Chapter 23: Blood-Brain Barrier Disruption in the Treatment of Brain Tumors. In The Blood-Brain and Other Neural Barriers; Nag, S., Ed.; Humana Press: Totowa, NJ, 2011; Vol. 686, pp. 447-463.
-
(2011)
The Blood-Brain and Other Neural Barriers;
, vol.686
, pp. 447-463
-
-
Blanchette, M.1
Fortin, D.2
-
64
-
-
76749120847
-
Evaluation of pH-responsive liposomes containing amino acid-based zwitterionic lipids for improving intracellular drug delivery in vitro and in vivo
-
Obata, Y.; Tajima, S.; Takeoka, S. Evaluation of pH-responsive liposomes containing amino acid-based zwitterionic lipids for improving intracellular drug delivery in vitro and in vivo. J. Control. Release, 2010, 142, 267-276.
-
(2010)
J. Control. Release
, vol.142
, pp. 267-276
-
-
Obata, Y.1
Tajima, S.2
Takeoka, S.3
-
65
-
-
0030447660
-
Brain drug delivery of small molecules using immunoliposomes
-
Huwyler, J.; Wu, D.; Pardridge, W.M. Brain drug delivery of small molecules using immunoliposomes. Proc. Natl. Acad. Sci. U. S. A, 1996, 93, 14164-14169.
-
(1996)
Proc. Natl. Acad. Sci. U. S. A
, vol.93
, pp. 14164-14169
-
-
Huwyler, J.1
Wu, D.2
Pardridge, W.M.3
-
66
-
-
0037222013
-
Global non-viral gene transfer to the primate brain following intravenous administration
-
Zhang, Y.; Schlachetzki, F.; Pardridge, W. Global non-viral gene transfer to the primate brain following intravenous administration. Mol. Ther., 2003, 7, 11-18.
-
(2003)
Mol. Ther
, vol.7
, pp. 11-18
-
-
Zhang, Y.1
Schlachetzki, F.2
Pardridge, W.3
-
67
-
-
84877256284
-
Enhanced Brain Delivery of the Opioid Peptide DAMGO in Glutathione PEGylated Liposomes: A Microdialysis Study
-
Lindqvist, A.; Rip, J.; Gaillard, P.J.; Björkman, S.; Hammarlund-Udenaes, M. Enhanced Brain Delivery of the Opioid Peptide DAMGO in Glutathione PEGylated Liposomes: A Microdialysis Study. Mol. Pharm., 2013, 10, 1533-1541.
-
(2013)
Mol. Pharm
, vol.10
, pp. 1533-1541
-
-
Lindqvist, A.1
Rip, J.2
Gaillard, P.J.3
Björkman, S.4
Hammarlund-Udenaes, M.5
-
68
-
-
77955466238
-
Nanoparticle-mediated brain-specific drug delivery, imaging, and diagnosis
-
Yang, H. Nanoparticle-mediated brain-specific drug delivery, imaging, and diagnosis. Pharm. Res., 2010, 27, 1759-1771.
-
(2010)
Pharm. Res
, vol.27
, pp. 1759-1771
-
-
Yang, H.1
-
69
-
-
34548482374
-
Stealth liposomes: Review of the basic science, rationale, and clinical applications, existing and potential
-
Immordino, M.L.; Dosio, F.; Cattel, L. Stealth liposomes: review of the basic science, rationale, and clinical applications, existing and potential. Int. J. Nanomedicine, 2006, 1, 297-315.
-
(2006)
Int. J. Nanomedicine
, vol.1
, pp. 297-315
-
-
Immordino, M.L.1
Dosio, F.2
Cattel, L.3
-
70
-
-
0020597630
-
Transferrin receptors in human tissues: Their distribution and possible clinical relevance
-
Gatter, K.C.; Brown, G.; Trowbridge, I.S.; Woolston, R.E.; Mason, D.Y. Transferrin receptors in human tissues: their distribution and possible clinical relevance. J. Clin. Pathol., 1983, 36, 539-545.
-
(1983)
J. Clin. Pathol
, vol.36
, pp. 539-545
-
-
Gatter, K.C.1
Brown, G.2
Trowbridge, I.S.3
Woolston, R.E.4
Mason, D.Y.5
-
71
-
-
0032830130
-
The transferrin receptor: Role in health and disease
-
Ponka, P.; Lok, C.N. The transferrin receptor: role in health and disease. Int. J. Biochem. Cell Biol., 1999, 31, 1111-1137.
-
(1999)
Int. J. Biochem. Cell Biol
, vol.31
, pp. 1111-1137
-
-
Ponka, P.1
Lok, C.N.2
-
72
-
-
0036889760
-
-
Qian, Z.M.; Li, H.; Sun, H.; Ho, K. Targeted Drug Delivery via the Transferrin Receptor-. 2002, 54, 561-587.
-
(2002)
Targeted Drug Delivery Via the Transferrin Receptor
, vol.54
, pp. 561-587
-
-
Qian, Z.M.1
Li, H.2
Sun, H.3
Ho, K.4
-
73
-
-
84893713757
-
Glutathione as Potential Target for Cancer Therapy; More or Less is Good?
-
Abdalla, M.Y. Glutathione as Potential Target for Cancer Therapy; More or Less is Good? Jordan J. Biol. Sci., 2011, 4, 119-124.
-
(2011)
Jordan J. Biol. Sci
, vol.4
, pp. 119-124
-
-
Abdalla, M.Y.1
-
74
-
-
80051930096
-
Cytotoxicity Tests of Water Soluble ZnS and CdS Quantum Dots
-
Li, H.; Li, M.; Shih, W.Y.; Lelkes, P.I.; Shih, W.-H. Cytotoxicity Tests of Water Soluble ZnS and CdS Quantum Dots. J. Nanosci. Nanotechnol., 2011, 11, 3543-3551.
-
(2011)
J. Nanosci. Nanotechnol
, vol.11
, pp. 3543-3551
-
-
Li, H.1
Li, M.2
Shih, W.Y.3
Lelkes, P.I.4
Shih, W.-H.5
-
75
-
-
34547801806
-
Proin-flammogenic effects of low-toxicity and metal nanoparticles in vivo and in vitro: Highlighting the role of particle surface area and surface reactivity
-
Duffin, R.; Tran, L.; Brown, D.; Stone, V.; Donaldson, K. Proin-flammogenic effects of low-toxicity and metal nanoparticles in vivo and in vitro: highlighting the role of particle surface area and surface reactivity. Inhal. Toxicol., 2007, 19, 849-856.
-
(2007)
Inhal. Toxicol
, vol.19
, pp. 849-856
-
-
Duffin, R.1
Tran, L.2
Brown, D.3
Stone, V.4
Donaldson, K.5
-
76
-
-
34548832559
-
Cellular toxicity of various inhalable metal nanoparticles on human alveolar epithelial cells
-
Park, S.; Lee, Y.K.; Jung, M.; Kim, K.H.; Chung, N.; Ahn, E.-K.; Lim, Y.; Lee, K.-H. Cellular toxicity of various inhalable metal nanoparticles on human alveolar epithelial cells. Inhal. Toxicol., 2007, 19 Suppl 1, 59-65.
-
(2007)
Inhal. Toxicol
, vol.19
, Issue.SUPPL. 1
, pp. 59-65
-
-
Park, S.1
Lee, Y.K.2
Jung, M.3
Kim, K.H.4
Chung, N.5
Ahn, E.-K.6
Lim, Y.7
Lee, K.-H.8
-
77
-
-
84866480382
-
A nanoscale drug delivery carrier using nucleic acid aptamers for extended release of therapeutic
-
Sundaram, P.; Wower, J.; Byrne, M.E. A nanoscale drug delivery carrier using nucleic acid aptamers for extended release of therapeutic. Nanomedicine, 2012, 8, 1143-1151.
-
(2012)
Nanomedicine
, vol.8
, pp. 1143-1151
-
-
Sundaram, P.1
Wower, J.2
Byrne, M.E.3
-
78
-
-
85039607636
-
Controlled and Extended Release of Daunomycin from DNA Aptamer-Programmed Gold Nanoparticles
-
Sundaram, P.; Kurniawan, H.; Wower, J.; Byrne, M.E. Controlled and Extended Release of Daunomycin from DNA Aptamer-Programmed Gold Nanoparticles. Trans. Soc, Biomater., 2012, 35, 542.
-
(2012)
Trans. Soc, Biomater
, vol.35
, pp. 542
-
-
Sundaram, P.1
Kurniawan, H.2
Wower, J.3
Byrne, M.E.4
-
79
-
-
27944494819
-
Development and brain delivery of chi-tosan-PEG nanoparticles functionalized with the monoclonal antibody OX26
-
Aktas, Y.; Yemisci, M.; Andrieux, K.; Gürsoy, R.N.; Alonso, M.J.; Fernandez-Megia, E.; Novoa-Carballal, R.; Quiñoá, E.; Riguera, R.; Sargon, M.F.; Celik, H.H.; Demir, A.S.; Hincal, A.A.; Dalkara, T.; Capan, Y.; Couvreur, P. Development and brain delivery of chi-tosan-PEG nanoparticles functionalized with the monoclonal antibody OX26. Bioconjug. Chem., 2005, 16, 1503-1511.
-
(2005)
Bioconjug. Chem
, vol.16
, pp. 1503-1511
-
-
Aktas, Y.1
Yemisci, M.2
Andrieux, K.3
Gürsoy, R.N.4
Alonso, M.J.5
Fernandez-Megia, E.6
Novoa-Carballal, R.7
Quiñoá, E.8
Riguera, R.9
Sargon, M.F.10
Celik, H.H.11
Demir, A.S.12
Hincal, A.A.13
Dalkara, T.14
Capan, Y.15
Couvreur, P.16
-
80
-
-
79959866972
-
Magnetic brain tumor targeting and biodistribution of long-circulating PEG-modified, cross-linked starch-coated iron oxide nanoparticles
-
Cole, A.J.; David, A.E.; Wang, J.; Galbán, C.J.; Yang, V.C. Magnetic brain tumor targeting and biodistribution of long-circulating PEG-modified, cross-linked starch-coated iron oxide nanoparticles. Biomaterials, 2011, 32, 6291-6301.
-
(2011)
Biomaterials
, vol.32
, pp. 6291-6301
-
-
Cole, A.J.1
David, A.E.2
Wang, J.3
Galbán, C.J.4
Yang, V.C.5
-
81
-
-
84866508055
-
Enhanced delivery of gold nanoparticles with therapeutic potential into the brain using MRI-guided focused ultrasound
-
Etame, A.B.; Diaz, R.J.; O'Reilly, M.A.; Smith, C.A.; Mainprize, T.G.; Hynynen, K.; Rutka, J.T. Enhanced delivery of gold nanoparticles with therapeutic potential into the brain using MRI-guided focused ultrasound. Nanomedicine, 2012, 8, 1133-1142.
-
(2012)
Nanomedicine
, vol.8
, pp. 1133-1142
-
-
Etame, A.B.1
Diaz, R.J.2
O'Reilly, M.A.3
Smith, C.A.4
Mainprize, T.G.5
Hynynen, K.6
Rutka, J.T.7
-
82
-
-
79959874155
-
Magnetically-enabled and MR-monitored selective brain tumor protein delivery in rats via magnetic nanocarriers
-
Chertok, B.; David, A.E.; Yang, V.C. Magnetically-enabled and MR-monitored selective brain tumor protein delivery in rats via magnetic nanocarriers. Biomaterials, 2011, 32, 6245-6253.
-
(2011)
Biomaterials
, vol.32
, pp. 6245-6253
-
-
Chertok, B.1
David, A.E.2
Yang, V.C.3
-
83
-
-
77957013817
-
Magnetic resonance monitoring of focused ultrasound/magnetic nanoparticle targeting delivery of therapeutic agents to the brain
-
Liu, H.-L.; Hua, M.-Y.; Yang, H.-W.; Huang, C.-Y.; Chu, P.-C; Wu, J.-S.; Tseng, I.-C; Wang, J.-J.; Yen, T.-C; Chen, P.-Y.; Wei, K.-C. Magnetic resonance monitoring of focused ultrasound/magnetic nanoparticle targeting delivery of therapeutic agents to the brain. Proc. Natl. Acad. Sci. U. S. A, 2010, 107, 15205-15210.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A
, vol.107
, pp. 15205-15210
-
-
Liu, H.-L.1
Hua, M.-Y.2
Yang, H.-W.3
Huang, C.-Y.4
Chu, P.-C.5
Wu, J.-S.6
Tseng, I.-C.7
Wang, J.-J.8
Yen, T.-C.9
Chen, P.-Y.10
Wei, K.-C.11
-
84
-
-
64149094873
-
Stimuli-responsive polymersomes for programmed drug delivery
-
Meng, F.; Zhong, Z.; Feijen, J. Stimuli-responsive polymersomes for programmed drug delivery. Biomacromolecules, 2009, 10, 197-209.
-
(2009)
Biomacromolecules
, vol.10
, pp. 197-209
-
-
Meng, F.1
Zhong, Z.2
Feijen, J.3
-
86
-
-
4644232492
-
Block copolymer vesicles
-
Opsteen, J.; Cornelissen, J.; van Hest, J.C. Block copolymer vesicles. Pure Appl. Chem., 2004, 76, 1309-1319.
-
(2004)
Pure Appl. Chem
, vol.76
, pp. 1309-1319
-
-
Opsteen, J.1
Cornelissen, J.2
van Hest, J.C.3
-
87
-
-
0038103614
-
Biodegradable Polymersomes
-
Meng, F.; Hiemstra, C; Engbers, G.H.M.; Feijen, J. Biodegradable Polymersomes. Macromolecules, 2003, 36, 3004-3006.
-
(2003)
Macromolecules
, vol.36
, pp. 3004-3006
-
-
Meng, F.1
Hiemstra, C.2
Engbers, G.H.M.3
Feijen, J.4
-
88
-
-
66149140264
-
Stimuli-responsive polymersomes as nanocarriers for drug and gene delivery
-
Onaca, O.; Enea, R.; Hughes, D.W.; Meier, W. Stimuli-responsive polymersomes as nanocarriers for drug and gene delivery. Macro-mol. Biosci., 2009, 9, 129-139.
-
(2009)
Macro-mol. Biosci
, vol.9
, pp. 129-139
-
-
Onaca, O.1
Enea, R.2
Hughes, D.W.3
Meier, W.4
-
89
-
-
84861584761
-
Polymersomes for drug delivery: Design, formation and characterization
-
Lee, J.S.; Feijen, J. Polymersomes for drug delivery: design, formation and characterization. J. Control. Release, 2012, 161, 473-483.
-
(2012)
J. Control. Release
, vol.161
, pp. 473-483
-
-
Lee, J.S.1
Feijen, J.2
-
91
-
-
1842526004
-
Self-porating polymersomes of PEG-PLA and PEG-PCL: Hydrolysis-triggered controlled release vesicles
-
Ahmed, F.; Discher, D.E. Self-porating polymersomes of PEG-PLA and PEG-PCL: hydrolysis-triggered controlled release vesicles. J. Control. Release, 2004, 96, 37-53.
-
(2004)
J. Control. Release
, vol.96
, pp. 37-53
-
-
Ahmed, F.1
Discher, D.E.2
-
92
-
-
78649450675
-
Self-assembled vesicles of am-phiphilic poly(dimethylsiloxane)-b-poly(ethylene glycol) copolymers as nanotanks for hydrophobic drugs
-
Li, D.; Li, C; Wan, G.; Hou, W. Self-assembled vesicles of am-phiphilic poly(dimethylsiloxane)-b-poly(ethylene glycol) copolymers as nanotanks for hydrophobic drugs. Colloids Surfaces A Physicochem. Eng. Asp., 2010, 372, 1-8.
-
(2010)
Colloids Surfaces a Physicochem. Eng. Asp
, vol.372
, pp. 1-8
-
-
Li, D.1
Li, C.2
Wan, G.3
Hou, W.4
-
93
-
-
26844449055
-
Synthesis, characterization and properties of chitosan modified with polyethylene glycol)-polydimethylsiloxane amphiphilic block copolymers
-
Rutnakornpituk, M.; Ngamdee, P.; Phinyocheep, P. Synthesis, characterization and properties of chitosan modified with polyethylene glycol)-polydimethylsiloxane amphiphilic block copolymers. Polymer. 2005, 46, 9742-9752.
-
(2005)
Polymer
, vol.46
, pp. 9742-9752
-
-
Rutnakornpituk, M.1
Ngamdee, P.2
Phinyocheep, P.3
-
94
-
-
84874935837
-
Brushlike amphiphilic copolymers based on polylactide and polyethylene glycol): Synthesis, self-assembly and evaluation as drug carrier
-
Bakkour, Y.; Darcos, V.; Coumes, F.; Li, S.; Coudane, J. Brushlike amphiphilic copolymers based on polylactide and polyethylene glycol): Synthesis, self-assembly and evaluation as drug carrier. Polymer. 2013, 54, 1746-1754.
-
(2013)
Polymer
, vol.54
, pp. 1746-1754
-
-
Bakkour, Y.1
Darcos, V.2
Coumes, F.3
Li, S.4
Coudane, J.5
-
95
-
-
1842541520
-
From su-pramolecular polymersomes to stimuli-responsive nano-capsules based on poly(diene-b-peptide) diblock copolymers
-
Chécot, F.; Lecommandoux, S.; Klok, H.; Gnanou, Y. From su-pramolecular polymersomes to stimuli-responsive nano-capsules based on poly(diene-b-peptide) diblock copolymers. Eur. Phys. J. E. Soft Matter, 2003, 10, 25-35.
-
(2003)
Eur. Phys. J. E. Soft Matter
, vol.10
, pp. 25-35
-
-
Chécot, F.1
Lecommandoux, S.2
Klok, H.3
Gnanou, Y.4
-
96
-
-
43449094024
-
Preparation and brain delivery property of biodegradable polymersomes conjugated with OX26
-
Pang, Z.; Lu, W.; Gao, H.; Hu, K.; Chen, J.; Zhang, C; Gao, X.; Jiang, X.; Zhu, C. Preparation and brain delivery property of biodegradable polymersomes conjugated with OX26. J. Control. Release, 2008, 128, 120-127.
-
(2008)
J. Control. Release
, vol.128
, pp. 120-127
-
-
Pang, Z.1
Lu, W.2
Gao, H.3
Hu, K.4
Chen, J.5
Zhang, C.6
Gao, X.7
Jiang, X.8
Zhu, C.9
-
97
-
-
79960199617
-
Brain delivery and cellular internalization mechanisms for transferrin conjugated biodegradable polymersomes
-
Pang, Z.; Gao, H.; Yu, Y.; Chen, J.; Guo, L.; Ren, J.; Wen, Z.; Su, J.; Jiang, X. Brain delivery and cellular internalization mechanisms for transferrin conjugated biodegradable polymersomes. Int. J. Pharm., 2011, 415, 284-292.
-
(2011)
Int. J. Pharm
, vol.415
, pp. 284-292
-
-
Pang, Z.1
Gao, H.2
Yu, Y.3
Chen, J.4
Guo, L.5
Ren, J.6
Wen, Z.7
Su, J.8
Jiang, X.9
-
98
-
-
77955769665
-
Transferrin-conjugated nanoparticles of poly(lactide)-D-alpha-tocopheryl polyethylene glycol succinate diblock copolymer for targeted drug delivery across the blood-brain barrier
-
Gan, C.W.; Feng, S.-S. Transferrin-conjugated nanoparticles of poly(lactide)-D-alpha-tocopheryl polyethylene glycol succinate diblock copolymer for targeted drug delivery across the blood-brain barrier. Biomaterials, 2010, 31, 7748-7757.
-
(2010)
Biomaterials
, vol.31
, pp. 7748-7757
-
-
Gan, C.W.1
Feng, S.-S.2
-
99
-
-
84862001921
-
In vivo biodistribution of prion-and GM1-targeted polymersomes following intravenous administration in mice
-
Stojanov, K.; Georgieva, J.V.; Brinkhuis, R.P.; van Hest, J.C; Rutjes, F.P.; Dierckx, R.A.J.O.; de Vries, E.F.J.; Zunhorn, I.S. In vivo biodistribution of prion-and GM1-targeted polymersomes following intravenous administration in mice. Mol. Pharm., 2012, 9, 1620-1627.
-
(2012)
Mol. Pharm
, vol.9
, pp. 1620-1627
-
-
Stojanov, K.1
Georgieva, J.V.2
Brinkhuis, R.P.3
van Hest, J.C.4
Rutjes, F.P.5
Dierckx, R.A.J.O.6
de Vries, E.F.J.7
Zunhorn, I.S.8
-
100
-
-
84875294969
-
Controlled Delivery of Functional-ized Gold Nanoparticles by pH-Sensitive Polymersomes
-
Popescu, M.-T.; Tsitsilianis, C. Controlled Delivery of Functional-ized Gold Nanoparticles by pH-Sensitive Polymersomes. ACS Macro Lett., 2013, 2, 222-225.
-
(2013)
ACS Macro Lett
, vol.2
, pp. 222-225
-
-
Popescu, M.-T.1
Tsitsilianis, C.2
-
101
-
-
84877747508
-
Blood-brain barrier structure and function and the challenges for CNS drug delivery
-
Abbott, N.J. Blood-brain barrier structure and function and the challenges for CNS drug delivery. J. Inherit. Metab. Dis., 2013, 36, 437-449.
-
(2013)
J. Inherit. Metab. Dis
, vol.36
, pp. 437-449
-
-
Abbott, N.J.1
-
102
-
-
79951682931
-
The Blood-Cerebrospinal Fluid Barrier: Structure and Functional Significance
-
Nag, S., Ed.; Humana Press: Totowa, NJ
-
Johanson, C.E.; Stopa, E.G.; McMillan, P.N. The Blood-Cerebrospinal Fluid Barrier: Structure and Functional Significance. In The Blood-Brain and Other Neural Barriers; Nag, S., Ed.; Humana Press: Totowa, NJ, 2011; Vol. 686, pp. 101-131.
-
(2011)
The Blood-Brain and Other Neural Barriers
, vol.686
, pp. 101-131
-
-
Johanson, C.E.1
Stopa, E.G.2
McMillan, P.N.3
-
103
-
-
0037212701
-
Tight junction proteins
-
Betanzos, A.; Nava, P.; Jaramillo, B.E.; Gonz, L. Tight junction proteins. Prog. Biophys. Mol. Biol. 2003, 81, 1-44.
-
(2003)
Prog. Biophys. Mol. Biol
, vol.81
, pp. 1-44
-
-
Betanzos, A.1
Nava, P.2
Jaramillo, B.E.3
Gonz, L.4
-
104
-
-
0141749405
-
Structure and function of desmosomal proteins and their role in development and disease
-
Huber, O. Structure and function of desmosomal proteins and their role in development and disease. Cell. Mol. Life Sci., 2003, 60, 1872-1890.
-
(2003)
Cell. Mol. Life Sci
, vol.60
, pp. 1872-1890
-
-
Huber, O.1
-
105
-
-
0036841868
-
Glomerular Endothelial Fenestrae In Vivo Are Not Formed from Caveolae
-
Sorensson, J. Glomerular Endothelial Fenestrae In Vivo Are Not Formed from Caveolae. J. Am. Soc. Nephrol., 2002, 13, 2639-2647.
-
(2002)
J. Am. Soc. Nephrol
, vol.13
, pp. 2639-2647
-
-
Sorensson, J.1
-
106
-
-
84863266360
-
Caveolae, fenestrae and transen-dothelial channels retain PV1 on the surface of endothelial cells
-
Tkachenko, E.; Tse, D.; Sideleva, O.; Deharvengt, S.J.; Luciano, M.R.; Xu, Y.; McGarry, C.L.; Chidlow, J.; Pilch, P.F.; Sessa, W.C.; Toomre, D.K.; Stan, R.V. Caveolae, fenestrae and transen-dothelial channels retain PV1 on the surface of endothelial cells. PLoS One, 2012, 7, e32655.
-
(2012)
PLoS One
, vol.7
-
-
Tkachenko, E.1
Tse, D.2
Sideleva, O.3
Deharvengt, S.J.4
Luciano, M.R.5
Xu, Y.6
McGarry, C.L.7
Chidlow, J.8
Pilch, P.F.9
Sessa, W.C.10
Toomre, D.K.11
Stan, R.V.12
-
107
-
-
0024802648
-
Differential expression of three gap junction proteins in developing and mature brain tissues
-
Dermietzel, R.; Traub, O.; Hwang, T.K.; Beyer, E.; Bennett, M.V; Spray, D.C.; Willecke, K. Differential expression of three gap junction proteins in developing and mature brain tissues. Proc. Natl. Acad. Sci. U. S. A, 1989, 86, 10148-10152.
-
(1989)
Proc. Natl. Acad. Sci. U. S. A
, vol.86
, pp. 10148-10152
-
-
Dermietzel, R.1
Traub, O.2
Hwang, T.K.3
Beyer, E.4
Bennett, M.V.5
Spray, D.C.6
Willecke, K.7
-
108
-
-
0003571561
-
-
14th ed.; McGraw-Hill Health Professions Division: New York
-
Fauci, A.; Braunwald, E.; Isselbacher, K.; Wilson, J.; Marin, J.; Kasper, D.; Hauser, S.; Longo, D. Harrison's principles of internal medicine; 14th ed.; McGraw-Hill Health Professions Division: New York, 1998; pp. A2-A8.
-
(1998)
Harrison's Principles of Internal Medicine
-
-
Fauci, A.1
Braunwald, E.2
Isselbacher, K.3
Wilson, J.4
Marin, J.5
Kasper, D.6
Hauser, S.7
Longo, D.8
-
109
-
-
84866372345
-
Intravenous Injection/Pharmacokinetics
-
Pardridge, W. M., Ed.; Cambridge University Press
-
Bickel, U. Intravenous Injection/Pharmacokinetics. In Introduction to the Blood-Brain Barrier: Methodology, Biology, and Pathology; Pardridge, W. M., Ed.; Cambridge University Press, 2006; pp. 41-47.
-
(2006)
Introduction to The Blood-Brain Barrier: Methodology, Biology, and Pathology
, pp. 41-47
-
-
Bickel, U.1
-
110
-
-
0035292828
-
Delivery of peptides and proteins through the blood-brain barrier
-
Bickel, U.; Yoshikawa, T.; Pardridge, W. Delivery of peptides and proteins through the blood-brain barrier. Adv. Drug Deliv. Rev., 2001, 46, 247-279.
-
(2001)
Adv. Drug Deliv. Rev
, vol.46
, pp. 247-279
-
-
Bickel, U.1
Yoshikawa, T.2
Pardridge, W.3
-
111
-
-
0005735688
-
Insulinlike growth factor II (IGF II) in human brain: Regional distribution of IGF II and of higher molecular mass forms
-
Haselbacher, G.K.; Schwab, M.E.; Pasi, A.; Humbel, R.E. Insulinlike growth factor II (IGF II) in human brain: regional distribution of IGF II and of higher molecular mass forms. Proc. Natl. Acad. Sci. U. S. A, 1985, 82, 2153-2157.
-
(1985)
Proc. Natl. Acad. Sci. U. S. A
, vol.82
, pp. 2153-2157
-
-
Haselbacher, G.K.1
Schwab, M.E.2
Pasi, A.3
Humbel, R.E.4
-
112
-
-
0029977219
-
Serum insulin-like growth factor II levels in normal adolescents and those with insulin dependent diabetes mellitus
-
Acerini, C.L.; Clayton, K.L.; Hintz, R.; Baker, B.; Watts, A.; Holly, J.M.; Dunger, D.B. Serum insulin-like growth factor II levels in normal adolescents and those with insulin dependent diabetes mellitus. Clin. Endocrinol. (Oxf). 1996, 45, 13-19.
-
(1996)
Clin. Endocrinol. (Oxf)
, vol.45
, pp. 13-19
-
-
Acerini, C.L.1
Clayton, K.L.2
Hintz, R.3
Baker, B.4
Watts, A.5
Holly, J.M.6
Dunger, D.B.7
-
114
-
-
0029974877
-
Adipose tissue leptin production and plasma leptin kinetics in humans
-
Klein, S.; Coppack, S.W.; Mohamed-Ali, V.; Landt, M. Adipose tissue leptin production and plasma leptin kinetics in humans. Diabetes, 1996, 45, 984-987.
-
(1996)
Diabetes
, vol.45
, pp. 984-987
-
-
Klein, S.1
Coppack, S.W.2
Mohamed-Ali, V.3
Landt, M.4
-
115
-
-
13344295079
-
Serum immunoreactive-leptin concentrations in normal-weight and obese humans
-
Considine, R.V; Sinha, M.K.; Heiman, M.L.; Kriauciunas, A.; Stephens, T.W.; Nyce, M.R.; Ohannesian, J.P.; Marco, C.C.; McKee, L.J.; Bauer, T.L. Serum immunoreactive-leptin concentrations in normal-weight and obese humans. N. Engl. J. Med., 1996, 334, 292-295.
-
(1996)
N. Engl. J. Med
, vol.334
, pp. 292-295
-
-
Considine, R.V.1
Sinha, M.K.2
Heiman, M.L.3
Kriauciunas, A.4
Stephens, T.W.5
Nyce, M.R.6
Ohannesian, J.P.7
Marco, C.C.8
McKee, L.J.9
Bauer, T.L.10
-
116
-
-
0024239015
-
The half-lives of IgG subclasses and specific antibodies in patients with primary immunodeficiency who are receiving intravenously administered
-
Mankarious, S.; Lee, M.; Fischer, S.; Pyun, K.; Ochs, H.; Oxelius, V.; Wedgwood, R. The half-lives of IgG subclasses and specific antibodies in patients with primary immunodeficiency who are receiving intravenously administered. J. Lab. Clin. Med., 1988, 112, 634-640.
-
(1988)
J. Lab. Clin. Med
, vol.112
, pp. 634-640
-
-
Mankarious, S.1
Lee, M.2
Fischer, S.3
Pyun, K.4
Ochs, H.5
Oxelius, V.6
Wedgwood, R.7
-
117
-
-
34848883058
-
Decreased circulation time offsets increased efficacy of PEGylated nanocarri-ers targeting folate receptors of glioma
-
McNeeley, K.M.; Annapragada, A.; Bellamkonda, R.V Decreased circulation time offsets increased efficacy of PEGylated nanocarri-ers targeting folate receptors of glioma. Nanotechnology, 2007, 18, 385101.
-
(2007)
Nanotechnology
, vol.18
, pp. 385101
-
-
McNeeley, K.M.1
Annapragada, A.2
Bellamkonda, R.V.3
-
118
-
-
67349259953
-
Masking and triggered unmasking of targeting ligands on nanocarriers to improve drug delivery to brain tumors
-
McNeeley, K.M.; Karathanasis, E.; Annapragada, A.V; Bellamkonda, R.V. Masking and triggered unmasking of targeting ligands on nanocarriers to improve drug delivery to brain tumors. Biomaterials, 2009, 30, 3986-3995.
-
(2009)
Biomaterials
, vol.30
, pp. 3986-3995
-
-
McNeeley, K.M.1
Karathanasis, E.2
Annapragada, A.V.3
Bellamkonda, R.V.4
-
119
-
-
84873449630
-
Cell penetrating peptide tethered bi-ligand liposomes for delivery to brain in vivo: Biodistribution and transfection
-
Sharma, G.; Modgil, A.; Layek, B.; Arora, K.; Sun, C.; Law, B.; Singh, J. Cell penetrating peptide tethered bi-ligand liposomes for delivery to brain in vivo: Biodistribution and transfection. J. Control. Release, 2013, 167, 1-10.
-
(2013)
J. Control. Release
, vol.167
, pp. 1-10
-
-
Sharma, G.1
Modgil, A.2
Layek, B.3
Arora, K.4
Sun, C.5
Law, B.6
Singh, J.7
-
120
-
-
84864313094
-
Delivery of gold nanoparticles to the brain by conjugation with a peptide that recognizes the transferrin receptor
-
Prades, R.; Guerrero, S.; Araya, E.; Molina, C.; Salas, E.; Zurita, E.; Selva, J.; Egea, G.; López-Iglesias, C.; Teixidó, M.; Kogan, M. J.; Giralt, E. Delivery of gold nanoparticles to the brain by conjugation with a peptide that recognizes the transferrin receptor. Bioma-terials, 2012, 33, 7194-7205.
-
(2012)
Bioma-terials
, vol.33
, pp. 7194-7205
-
-
Prades, R.1
Guerrero, S.2
Araya, E.3
Molina, C.4
Salas, E.5
Zurita, E.6
Selva, J.7
Egea, G.8
López-Iglesias, C.9
Teixidó, M.10
Kogan, M.J.11
Giralt, E.12
-
121
-
-
59049097859
-
Lactoferrin-conjugated PEG-PLA nanoparticles with improved brain delivery: In vitro and in vivo evaluations
-
Hu, K.; Li, J.; Shen, Y.; Lu, W.; Gao, X.; Zhang, Q.; Jiang, X. Lactoferrin-conjugated PEG-PLA nanoparticles with improved brain delivery: in vitro and in vivo evaluations. J. Control. Release, 2009, 134, 55-61.
-
(2009)
J. Control. Release
, vol.134
, pp. 55-61
-
-
Hu, K.1
Li, J.2
Shen, Y.3
Lu, W.4
Gao, X.5
Zhang, Q.6
Jiang, X.7
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