Challenges in drug delivery to the brain: Nature is against us

Journal of Controlled Release

Volumn 164, Issue 2, 2012, Pages 145-155

  Krol, Silke ^a  

^a DEPARTMENT OF NEUROSURGERY   (Italy)

Author keywords

Body physics; Brain drug delivery; Brain physics; Crowding; Targeted delivery

Indexed keywords

BIOCHEMISTRY; BLOOD VESSELS; BRAIN; CONTROLLED DRUG DELIVERY; DRUG INTERACTIONS; HISTOLOGY; MEDICAL APPLICATIONS; MEDICAL NANOTECHNOLOGY; NANOPARTICLES; NEURODEGENERATIVE DISEASES; NEURONS; TISSUE;

BLOOD-BRAIN BARRIER; BRAIN DRUG DELIVERIES; BRAIN PHYSICS; CONTROLLED RELEASE; CROWDING; MULTI-FUNCTIONAL NANOPARTICLES; PATHOLOGICAL CHANGES; TARGETED DELIVERY;

TARGETED DRUG DELIVERY;

ALBUMIN; ALPHA 1 ANTITRYPSIN; APOLIPOPROTEIN A1; APOLIPOPROTEIN A2; CELL RECEPTOR; FIBRINOGEN; HAPTOGLOBIN; HEMOPEXIN; IMMUNOGLOBULIN G; LIPOSOME; NANOPARTICLE; PREALBUMIN; SINGLE WALLED NANOTUBE; TRANSFERRIN;

ASTROCYTE; BLOOD BRAIN BARRIER; BLOOD VESSEL PERMEABILITY; BODY MOVEMENT; BRAIN; BRAIN CANCER; BRAIN MICROCIRCULATION; BRAIN TUMOR; CELL TYPE; CIRCULATION; DEGENERATIVE DISEASE; DILUTION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG TARGETING; ENDOTHELIUM; GLIA; GLIA CELL; HUMAN; MEMORY; NANOMEDICINE; NERVE CELL; OLIGODENDROGLIA; OPSONIZATION; PERICYTE; PERSONALITY; PRIORITY JOURNAL; PROTEIN BINDING; REVIEW; SENSORY SYSTEM; TRANSCYTOSIS;

EID: 84869498477     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2012.04.044     Document Type: Article

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