Magnetic brain tumor targeting and biodistribution of long-circulating PEG-modified, cross-linked starch-coated iron oxide nanoparticles

Biomaterials

Volumn 32, Issue 26, 2011, Pages 6291-6301

  Cole, Adam J ^a   David, Allan E ^a,c   Wang, Jianxin ^a,d   Galbán, Craig J ^b   Yang, Victor C ^a,e  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c Industrial Science and Technology Network Inc   (United States)

^d FUDAN UNIVERSITY   (China)

^e TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

Brain tumor; Drug delivery; Magnetic nanoparticles; Magnetic targeting; Pharmacokinetics; Polyethylene glycol (PEG)

Indexed keywords

BIODISTRIBUTIONS; BRAIN TUMORS; CROSS-LINKED STARCH; EXTERNAL MAGNETIC FIELD; FURTHER DEVELOPMENT; HISTOLOGICAL ANALYSIS; IRON OXIDE NANOPARTICLE; MAGNETIC IRON OXIDE NANOPARTICLES; MAGNETIC NANOPARTICLES; MAGNETIC TARGETING; PASSIVE MECHANISM; PROOF OF CONCEPT; RAT MODEL; TIME POINTS;

BIOLOGICAL ORGANS; DRUG DELIVERY; GLYCOLS; IRON OXIDES; MAGNETIC FIELDS; NANOPARTICLES; PHARMACOKINETICS; POLYETHYLENE GLYCOLS; POLYETHYLENES; STARCH; THERMOPLASTICS; TUMORS;

NANOMAGNETICS;

IRON OXIDE; MACROGOL; MAGNETIC NANOPARTICLE; STARCH;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN TUMOR; CANCER THERAPY; CIRCULATION; CROSS LINKING; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG RETENTION; GLIOMA; HISTOLOGY; KIDNEY; LIVER; LUNG; MALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PLASMA; PRIORITY JOURNAL; RAT; SPLEEN; TISSUE LEVEL;

ANIMALS; BRAIN NEOPLASMS; FERRIC COMPOUNDS; MAGNETIC RESONANCE IMAGING; MALE; NANOPARTICLES; POLYETHYLENE GLYCOLS; RATS; RATS, INBRED F344; STARCH;

RATTUS;

EID: 79959866972     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.05.024     Document Type: Article

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