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Volumn 99, Issue 1, 1997, Pages 14-18

Human blood-brain barrier leptin receptor. Binding and endocytosis in isolated human brain microvessels

Author keywords

central nervous system; cerebrovascular; OB protein; OB R; obesity

Indexed keywords

ARTICLE; AUTORADIOGRAPHY; BLOOD BRAIN BARRIER; BRAIN TISSUE; CEREBROSPINAL FLUID ANALYSIS; DISEASE ASSOCIATION; ENDOCYTOSIS; HUMAN; HUMAN TISSUE; MICROVASCULATURE; OBESITY; PRIORITY JOURNAL; PROTEIN BINDING; RADIOACTIVITY;

EID: 0031017561     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119125     Document Type: Article
Times cited : (351)

References (39)
  • 3
    • 0029048408 scopus 로고
    • Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks
    • Campfield, C.A., F.J. Smith, Y. Guisez, R. Devas, and P. Burn. 1995. Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks. Science (Wash. DC). 269:546-549.
    • (1995) Science (Wash. DC) , vol.269 , pp. 546-549
    • Campfield, C.A.1    Smith, F.J.2    Guisez, Y.3    Devas, R.4    Burn, P.5
  • 14
    • 0029881125 scopus 로고    scopus 로고
    • Cerebrospinal fluid leptin levels: Relationship to plasma levels and to adiposity in humans
    • Schwartz, M.W., E. Peskind, M. Raskind, E.J. Boyko, and D. Porte, Jr. 1996. Cerebrospinal fluid leptin levels: relationship to plasma levels and to adiposity in humans. Nat. Med. 2:589-593.
    • (1996) Nat. Med. , vol.2 , pp. 589-593
    • Schwartz, M.W.1    Peskind, E.2    Raskind, M.3    Boyko, E.J.4    Porte Jr., D.5
  • 17
    • 0029932592 scopus 로고    scopus 로고
    • Autoradiographic localization of leptin binding in the choroid plexus of ob/ob and db/db mice
    • Lynn, R.B., G.-Y. Cao, R.V. Considine, T.M. Hyde, and J.F. Caro. 1996. Autoradiographic localization of leptin binding in the choroid plexus of ob/ob and db/db mice. Biochem. Biophys. Res. Commun. 219:884-889.
    • (1996) Biochem. Biophys. Res. Commun. , vol.219 , pp. 884-889
    • Lynn, R.B.1    Cao, G.-Y.2    Considine, R.V.3    Hyde, T.M.4    Caro, J.F.5
  • 18
    • 0029986894 scopus 로고    scopus 로고
    • Localization of binding sites in the central nervous system for leptin (OB protein) in normal, obese (ob/ob), and diabetic (db/db) C57BL/6J mice
    • Malik, K.F., and W.S. Young III. 1996. Localization of binding sites in the central nervous system for leptin (OB protein) in normal, obese (ob/ob), and diabetic (db/db) C57BL/6J mice. Endocrinology. 137:1497-1500.
    • (1996) Endocrinology , vol.137 , pp. 1497-1500
    • Malik, K.F.1    Young III, W.S.2
  • 20
    • 0022764022 scopus 로고
    • Receptor-mediated peptide transport through the blood-brain barrier
    • Pardridge, W.M. 1986. Receptor-mediated peptide transport through the blood-brain barrier. Endocr. Rev. 7:314-330.
    • (1986) Endocr. Rev. , vol.7 , pp. 314-330
    • Pardridge, W.M.1
  • 21
    • 0021841594 scopus 로고
    • Human blood-brain barrier insulin receptor
    • Pardridge, W.M., J. Eisenberg, and J. Yang. 1985. Human blood-brain barrier insulin receptor. J. Neurochem. 44:1771-1778.
    • (1985) J. Neurochem. , vol.44 , pp. 1771-1778
    • Pardridge, W.M.1    Eisenberg, J.2    Yang, J.3
  • 22
    • 0023636719 scopus 로고
    • Blood-brain barrier transcytosis of insulin in developing rabbits
    • Duffy, K.R., and W.M. Pardridge. 1987. Blood-brain barrier transcytosis of insulin in developing rabbits. Brain Res. 420:32-38.
    • (1987) Brain Res. , vol.420 , pp. 32-38
    • Duffy, K.R.1    Pardridge, W.M.2
  • 23
    • 0027984463 scopus 로고
    • Insulin-like growth factors cross the blood-brain barrier
    • Reinhardt, R.R., and C.A. Bondy. 1994. Insulin-like growth factors cross the blood-brain barrier. Endocrinology. 135:1753-1761.
    • (1994) Endocrinology , vol.135 , pp. 1753-1761
    • Reinhardt, R.R.1    Bondy, C.A.2
  • 25
    • 0028079865 scopus 로고
    • In vivo demonstration of subcellular localization of anti-transferrin receptor monoclonal antibody-colloidal gold conjugate within brain capillary endothelium
    • Bickel, U., Y.-S. Kang, T. Yoshikawa, and W.M. Pardridge. 1994. In vivo demonstration of subcellular localization of anti-transferrin receptor monoclonal antibody-colloidal gold conjugate within brain capillary endothelium. J. Histochem. Cytochem. 42:1493-1497.
    • (1994) J. Histochem. Cytochem. , vol.42 , pp. 1493-1497
    • Bickel, U.1    Kang, Y.-S.2    Yoshikawa, T.3    Pardridge, W.M.4
  • 27
    • 0021965663 scopus 로고
    • Rapid sequestration and degradation of somatostatin analogues by isolated brain microvessels
    • Pardridge, W.M., J. Eisenberg, and T. Yamada. 1985. Rapid sequestration and degradation of somatostatin analogues by isolated brain microvessels. J. Neurochem. 44:1178-1184.
    • (1985) J. Neurochem. , vol.44 , pp. 1178-1184
    • Pardridge, W.M.1    Eisenberg, J.2    Yamada, T.3
  • 28
    • 0022506238 scopus 로고
    • Binding and internalization of insulin and insulin-like growth factors by isolated brain microvessels
    • Frank, H.J.L., W.M. Pardridge, W.L. Morris, R.G. Rosenfeld, and T.B. Choi. 1986. Binding and internalization of insulin and insulin-like growth factors by isolated brain microvessels. Diabetes. 35:654-661.
    • (1986) Diabetes , vol.35 , pp. 654-661
    • Frank, H.J.L.1    Pardridge, W.M.2    Morris, W.L.3    Rosenfeld, R.G.4    Choi, T.B.5
  • 29
    • 0021026190 scopus 로고
    • Characterization of the blood-brain barrier: Protein composition of the capillary endothelial cell membrane
    • Lidinsky, W.A., and L.R. Drewes. 1983. Characterization of the blood-brain barrier: protein composition of the capillary endothelial cell membrane. J. Neurochem. 41:1341-1348.
    • (1983) J. Neurochem. , vol.41 , pp. 1341-1348
    • Lidinsky, W.A.1    Drewes, L.R.2
  • 30
    • 0019909034 scopus 로고
    • 125I-insulin in adipocytes and IM-9 lymphocytes
    • 125I-insulin in adipocytes and IM-9 lymphocytes. J. Biol. Chem. 257: 8667-8673.
    • (1982) J. Biol. Chem. , vol.257 , pp. 8667-8673
    • Olefsky, J.M.1    Kao, M.2
  • 31
    • 0015386271 scopus 로고
    • Mathematical theory of complex ligand-binding systems of equilibrium: Some methods for parameter fitting
    • Feldman, H.A. 1972. Mathematical theory of complex ligand-binding systems of equilibrium: some methods for parameter fitting. Anal. Biochem. 48: 317-338.
    • (1972) Anal. Biochem. , vol.48 , pp. 317-338
    • Feldman, H.A.1
  • 34
    • 0023830889 scopus 로고
    • Human blood-brain barrier insulin-like growth factor receptor
    • Duffy, K.R., W.M. Pardridge, and R.G. Rosenfeld. 1988. Human blood-brain barrier insulin-like growth factor receptor. Metab. Clin. Exp. 37:136-140.
    • (1988) Metab. Clin. Exp. , vol.37 , pp. 136-140
    • Duffy, K.R.1    Pardridge, W.M.2    Rosenfeld, R.G.3
  • 35
    • 0023227218 scopus 로고
    • Human blood-brain barrier transferrin receptor
    • Pardridge, W.M., J. Eisenberg, and J. Yang. 1987. Human blood-brain barrier transferrin receptor. Metab. Clin. Exp. 36:892-895.
    • (1987) Metab. Clin. Exp. , vol.36 , pp. 892-895
    • Pardridge, W.M.1    Eisenberg, J.2    Yang, J.3
  • 36
    • 0029864416 scopus 로고    scopus 로고
    • Leptin enters the brain by a saturable system independent of insulin
    • Banks, W.A., A.J. Kastin, W. Huant, J.B. Jaspan, and L.M. Maness. 1996. Leptin enters the brain by a saturable system independent of insulin. Peptides. 17:305-311.
    • (1996) Peptides , vol.17 , pp. 305-311
    • Banks, W.A.1    Kastin, A.J.2    Huant, W.3    Jaspan, J.B.4    Maness, L.M.5
  • 38
    • 13344259300 scopus 로고    scopus 로고
    • Evidence that the diabetes gene encodes the leptin receptor: Identification of a mutation in the leptin receptor gene in db/db mice
    • Chen, H., O. Charlat, L.A. Tartaglia, E.A. Woolf, X. Weng, S.J. Ellis, N.D. Lakey, J. Culpepper, K.J. Moore, R.E. Breitbart, et al. 1996. Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice. Cell. 84:491-495.
    • (1996) Cell , vol.84 , pp. 491-495
    • Chen, H.1    Charlat, O.2    Tartaglia, L.A.3    Woolf, E.A.4    Weng, X.5    Ellis, S.J.6    Lakey, N.D.7    Culpepper, J.8    Moore, K.J.9    Breitbart, R.E.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.