In vivo biodistribution of prion- and GM1-targeted polymersomes following intravenous administration in mice

Molecular Pharmaceutics

Volumn 9, Issue 6, 2012, Pages 1620-1627

  Stojanov, Katica ^a   Georgieva, Julia V ^a   Brinkhuis, René P ^b   Van Hest, Jan C ^b   Rutjes, Floris P ^b   Dierckx, Rudi A J O ^a   De Vries, Erik F J ^a   Zuhorn, Inge S ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

Author keywords

blood brain barrier; GM1; polymersomes; prion; transcytosis

Indexed keywords

CHOLERA TOXIN B SUBUNIT; GANGLIOSIDE GM1; NANOCARRIER; POLYMERSOME; PRION PROTEIN; PROTEIN P50; STREPTAVIDIN; TRANSFERRIN RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN BLOOD VESSEL; BRAIN DISEASE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG RELEASE; DRUG STABILITY; DRUG TARGETING; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIPOPHILICITY; MALE; MICROVASCULAR ENDOTHELIAL CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN TARGETING; TRANSCYTOSIS; VASCULAR ENDOTHELIUM;

ADMINISTRATION, INTRAVENOUS; ANIMALS; BLOOD-BRAIN BARRIER; DRUG DELIVERY SYSTEMS; G(M1) GANGLIOSIDE; MALE; MICE; MICE, INBRED BALB C; PRIONS;

EID: 84862001921     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp200621v     Document Type: Article

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