-
1
-
-
56349093347
-
IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(2) effector T cells
-
Dardalhon, V., A. Awasthi, H. Kwon, G. Galileos, W. Gao, R. A. Sobel, M. Mitsdoerffer, T. B. Strom, W. Elyaman, I. C. Ho, et al. 2008. IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(2) effector T cells. Nat. Immunol. 9: 1347-1355.
-
(2008)
Nat. Immunol
, vol.9
, pp. 1347-1355
-
-
Dardalhon, V.1
Awasthi, A.2
Kwon, H.3
Galileos, G.4
Gao, W.5
Sobel, R.A.6
Mitsdoerffer, M.7
Strom, T.B.8
Elyaman, W.9
Ho, I.C.10
-
2
-
-
56349154943
-
Transforming growth factorbeta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset
-
Veldhoen, M., C. Uyttenhove, J. van Snick, H. Helmby, A. Westendorf, J. Buer, B. Martin, C. Wilhelm, and B. Stockinger. 2008. Transforming growth factorbeta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset. Nat. Immunol. 9: 1341-1346.
-
(2008)
Nat. Immunol
, vol.9
, pp. 1341-1346
-
-
Veldhoen, M.1
Uyttenhove, C.2
Van Snick, J.3
Helmby, H.4
Westendorf, A.5
Buer, J.6
Martin, B.7
Wilhelm, C.8
Stockinger, B.9
-
3
-
-
84859997488
-
Notch receptors and Smad3 signaling cooperate in the induction of interleukin-9-producing T cells
-
Elyaman, W., R. Bassil, E. M. Bradshaw, W. Orent, Y. Lahoud, B. Zhu, F. Radtke, H. Yagita, and S. J. Khoury. 2012. Notch receptors and Smad3 signaling cooperate in the induction of interleukin-9-producing T cells. Immunity 36: 623-634.
-
(2012)
Immunity
, vol.36
, pp. 623-634
-
-
Elyaman, W.1
Bassil, R.2
Bradshaw, E.M.3
Orent, W.4
Lahoud, Y.5
Zhu, B.6
Radtke, F.7
Yagita, H.8
Khoury, S.J.9
-
4
-
-
69149107148
-
IL-9 induces differentiation of TH17 cells and enhances function of FoxP3+ natural regulatory T cells
-
Elyaman, W., E. M. Bradshaw, C. Uyttenhove, V. Dardalhon, A. Awasthi, J. Imitola, E. Bettelli, M. Oukka, J. van Snick, J. C. Renauld, et al. 2009. IL-9 induces differentiation of TH17 cells and enhances function of FoxP3+ natural regulatory T cells. Proc. Natl. Acad. Sci. USA 106: 12885-12890.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 12885-12890
-
-
Elyaman, W.1
Bradshaw, E.M.2
Uyttenhove, C.3
Dardalhon, V.4
Awasthi, A.5
Imitola, J.6
Bettelli, E.7
Oukka, M.8
Van Snick, J.9
Renauld, J.C.10
-
5
-
-
33748320914
-
Mast cells are essential intermediaries in regulatory T-cell tolerance
-
Lu, L. F., E. F. Lind, D. C. Gondek, K. A. Bennett, M. W. Gleeson, K. Pino-Lagos, Z. A. Scott, A. J. Coyle, J. L. Reed, J. Van Snick, et al. 2006. Mast cells are essential intermediaries in regulatory T-cell tolerance. Nature 442: 997-1002.
-
(2006)
Nature
, vol.442
, pp. 997-1002
-
-
Lu, L.F.1
Lind, E.F.2
Gondek, D.C.3
Bennett, K.A.4
Gleeson, M.W.5
Pino-Lagos, K.6
Scott, Z.A.7
Coyle, A.J.8
Reed, J.L.9
Van Snick, J.10
-
6
-
-
77957230475
-
Neutralization of IL-9 ameliorates experimental autoimmune encephalomyelitis by decreasing the effector T cell population
-
Li, H., B. Nourbakhsh, B. Ciric, G. X. Zhang, and A. Rostami. 2010. Neutralization of IL-9 ameliorates experimental autoimmune encephalomyelitis by decreasing the effector T cell population. J. Immunol. 185: 4095-4100.
-
(2010)
J. Immunol
, vol.185
, pp. 4095-4100
-
-
Li, H.1
Nourbakhsh, B.2
Ciric, B.3
Zhang, G.X.4
Rostami, A.5
-
7
-
-
73349109145
-
Th1, Th17, and Th9 effector cells induce experimental autoimmune encephalomyelitis with different pathological phenotypes
-
Jäger, A., V. Dardalhon, R. A. Sobel, E. Bettelli, and V. K. Kuchroo. 2009. Th1, Th17, and Th9 effector cells induce experimental autoimmune encephalomyelitis with different pathological phenotypes. J. Immunol. 183: 7169-7177.
-
(2009)
J. Immunol
, vol.183
, pp. 7169-7177
-
-
Jäger, A.1
Dardalhon, V.2
Sobel, R.A.3
Bettelli, E.4
Kuchroo, V.K.5
-
8
-
-
84864648969
-
Robust tumor immunity to melanoma mediated by interleukin-9-producing T cells
-
Purwar, R., C. Schlapbach, S. Xiao, H. S. Kang, W. Elyaman, X. Jiang, A. M. Jetten, S. J. Khoury, R. C. Fuhlbrigge, V. K. Kuchroo, et al. 2012. Robust tumor immunity to melanoma mediated by interleukin-9-producing T cells. Nat. Med. 18: 1248-1253.
-
(2012)
Nat. Med
, vol.18
, pp. 1248-1253
-
-
Purwar, R.1
Schlapbach, C.2
Xiao, S.3
Kang, H.S.4
Elyaman, W.5
Jiang, X.6
Jetten, A.M.7
Khoury, S.J.8
Fuhlbrigge, R.C.9
Kuchroo, V.K.10
-
9
-
-
84859137202
-
Activin A and TGF-beta promote T(H)9 cell-mediated pulmonary allergic pathology
-
Jones, C. P., L. G. Gregory, B. Causton, G. A. Campbell, and C. M. Lloyd. 2012. Activin A and TGF-beta promote T(H)9 cell-mediated pulmonary allergic pathology. J. Allergy Clin. Immunol. 129: 1000-1010.e3.
-
(2012)
J. Allergy Clin. Immunol
, vol.129
-
-
Jones, C.P.1
Gregory, L.G.2
Causton, B.3
Campbell, G.A.4
Lloyd, C.M.5
-
10
-
-
67651162130
-
Computational and functional analysis of growth hormone (GH)-regulated genes identifies the transcriptional repressor B-cell lymphoma 6 (Bc16) as a participant in GH-regulated transcription
-
Chen, Y., G. Lin, J. S. Huo, D. Barney, Z. Wang, T. Livshiz, D. J. States, Z. S. Qin, and J. Schwartz. 2009. Computational and functional analysis of growth hormone (GH)-regulated genes identifies the transcriptional repressor B-cell lymphoma 6 (Bc16) as a participant in GH-regulated transcription. Endocrinology 150: 3645-3654.
-
(2009)
Endocrinology
, vol.150
, pp. 3645-3654
-
-
Chen, Y.1
Lin, G.2
Huo, J.S.3
Barney, D.4
Wang, Z.5
Livshiz, T.6
States, D.J.7
Qin, Z.S.8
Schwartz, J.9
-
11
-
-
77958611660
-
Peripheral CD4+ T-cell differentiation regulated by networks of cytokines and transcription factors
-
Zhu, J., and W. E. Paul. 2010. Peripheral CD4+ T-cell differentiation regulated by networks of cytokines and transcription factors. Immunol. Rev. 238: 247-262.
-
(2010)
Immunol. Rev
, vol.238
, pp. 247-262
-
-
Zhu, J.1
Paul, W.E.2
-
12
-
-
77955902281
-
Interferon-regulatory factor 4 is essential for the developmental program of T helper 9 cells
-
Staudt, V., E. Bothur, M. Klein, K. Lingnau, S. Reuter, N. Grebe, B. Gerlitzki, M. Hoffmann, A. Ulges, C. Taube, et al. 2010. Interferon-regulatory factor 4 is essential for the developmental program of T helper 9 cells. Immunity 33: 192-202.
-
(2010)
Immunity
, vol.33
, pp. 192-202
-
-
Staudt, V.1
Bothur, E.2
Klein, M.3
Lingnau, K.4
Reuter, S.5
Grebe, N.6
Gerlitzki, B.7
Hoffmann, M.8
Ulges, A.9
Taube, C.10
-
13
-
-
84860851543
-
Nuclear factor of activated T cells 1 (NFAT1)-induced permissive chromatin modification facilitates nuclear factor-κB (NF-κB)- mediated interleukin-9 (IL-9) transactivation
-
Jash, A., A. Sahoo, G. C. Kim, C. S. Chae, J. S. Hwang, J. E. Kim, and S. H. Im. 2012. Nuclear factor of activated T cells 1 (NFAT1)-induced permissive chromatin modification facilitates nuclear factor-κB (NF-κB)- mediated interleukin-9 (IL-9) transactivation. J. Biol. Chem. 287: 15445-15457.
-
(2012)
J. Biol. Chem
, vol.287
, pp. 15445-15457
-
-
Jash, A.1
Sahoo, A.2
Kim, G.C.3
Chae, C.S.4
Hwang, J.S.5
Kim, J.E.6
Im, S.H.7
-
14
-
-
77952584843
-
The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation
-
Chang, H. C., S. Sehra, R. Goswami, W. Yao, Q. Yu, G. L. Stritesky, R. Jabeen, C. McKinley, A. N. Ahyi, L. Han, et al. 2010. The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation. Nat. Immunol. 11: 527-534.
-
(2010)
Nat. Immunol
, vol.11
, pp. 527-534
-
-
Chang, H.C.1
Sehra, S.2
Goswami, R.3
Yao, W.4
Yu, Q.5
Stritesky, G.L.6
Jabeen, R.7
McKinley, C.8
Ahyi, A.N.9
Han, L.10
-
15
-
-
84863010992
-
STAT6-dependent regulation of Th9 development
-
Goswami, R., R. Jabeen, R. Yagi, D. Pham, J. Zhu, S. Goenka, and M. H. Kaplan. 2012. STAT6-dependent regulation of Th9 development. J. Immunol. 188: 968-975.
-
(2012)
J. Immunol
, vol.188
, pp. 968-975
-
-
Goswami, R.1
Jabeen, R.2
Yagi, R.3
Pham, D.4
Zhu, J.5
Goenka, S.6
Kaplan, M.H.7
-
16
-
-
84874241774
-
Interleukin-9 is required for allergic airway inflammation mediated by the cytokine TSLP
-
Yao, W., Y. Zhang, R. Jabeen, E. T. Nguyen, D. S. Wilkes, R. S. Tepper, M. H. Kaplan, and B. Zhou. 2013. Interleukin-9 is required for allergic airway inflammation mediated by the cytokine TSLP. Immunity 38: 360-372.
-
(2013)
Immunity
, vol.38
, pp. 360-372
-
-
Yao, W.1
Zhang, Y.2
Jabeen, R.3
Nguyen, E.T.4
Wilkes, D.S.5
Tepper, R.S.6
Kaplan, M.H.7
Zhou, B.8
-
17
-
-
84868530014
-
Bcl6 controls the Th2 inflammatory activity of regulatory T cells by repressing Gata3 function
-
Sawant, D. V., S. Sehra, E. T. Nguyen, R. Jadhav, K. Englert, R. Shinnakasu, G. Hangoc, H. E. Broxmeyer, T. Nakayama, N. B. Perumal, et al. 2012. Bcl6 controls the Th2 inflammatory activity of regulatory T cells by repressing Gata3 function. J. Immunol. 189: 4759-4769.
-
(2012)
J. Immunol
, vol.189
, pp. 4759-4769
-
-
Sawant, D.V.1
Sehra, S.2
Nguyen, E.T.3
Jadhav, R.4
Englert, K.5
Shinnakasu, R.6
Hangoc, G.7
Broxmeyer, H.E.8
Nakayama, T.9
Perumal, N.B.10
-
18
-
-
77952780554
-
Transcriptional repressor BCL6 controls Th17 responses by controlling gene expression in both T cells and macrophages
-
Mondal, A., D. Sawant, and A. L. Dent. 2010. Transcriptional repressor BCL6 controls Th17 responses by controlling gene expression in both T cells and macrophages. J. Immunol. 184: 4123-4132.
-
(2010)
J. Immunol
, vol.184
, pp. 4123-4132
-
-
Mondal, A.1
Sawant, D.2
Dent, A.L.3
-
19
-
-
53149154521
-
Blimp-1 attenuates Th1 differentiation by repression of ifng, tbx21, and bcl6 gene expression
-
Cimmino, L., G. A. Martins, J. Liao, E. Magnusdottir, G. Grunig, R. K. Perez, and K. L. Calame. 2008. Blimp-1 attenuates Th1 differentiation by repression of ifng, tbx21, and bcl6 gene expression. J. Immunol. 181: 2338-2347.
-
(2008)
J. Immunol
, vol.181
, pp. 2338-2347
-
-
Cimmino, L.1
Martins, G.A.2
Liao, J.3
Magnusdottir, E.4
Grunig, G.5
Perez, R.K.6
Calame, K.L.7
-
20
-
-
0030901289
-
Control of inflammation, cytokine expression, and germinal center formation by BCL-6
-
Dent, A. L., A. L. Shaffer, X. Yu, D. Allman, and L. M. Staudt. 1997. Control of inflammation, cytokine expression, and germinal center formation by BCL-6. Science 276: 589-592.
-
(1997)
Science
, vol.276
, pp. 589-592
-
-
Dent, A.L.1
Shaffer, A.L.2
Yu, X.3
Allman, D.4
Staudt, L.M.5
-
21
-
-
17144439800
-
The BCL-6 protooncogene controls germinal-centre formation and Th2-type inflammation
-
Ye, B. H., G. Cattoretti, Q. Shen, J. Zhang, N. Hawe, R. de Waard, C. Leung, M. Nouri-Shirazi, A. Orazi, R. S. Chaganti, et al. 1997. The BCL-6 protooncogene controls germinal-centre formation and Th2-type inflammation. Nat. Genet. 16: 161-170.
-
(1997)
Nat. Genet
, vol.16
, pp. 161-170
-
-
Ye, B.H.1
Cattoretti, G.2
Shen, Q.3
Zhang, J.4
Hawe, N.5
De Waard, R.6
Leung, C.7
Nouri-Shirazi, M.8
Orazi, A.9
Chaganti, R.S.10
-
22
-
-
0034306290
-
STAT proteins and transcriptional responses to extracellular signals
-
Horvath, C. M. 2000. STAT proteins and transcriptional responses to extracellular signals. Trends Biochem. Sci. 25: 496-502.
-
(2000)
Trends Biochem. Sci
, vol.25
, pp. 496-502
-
-
Horvath, C.M.1
-
23
-
-
3142724732
-
Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis
-
Bettelli, E., B. Sullivan, S. J. Szabo, R. A. Sobel, L. H. Glimcher, and V. K. Kuchroo. 2004. Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis. J. Exp. Med. 200: 79-87.
-
(2004)
J. Exp. Med
, vol.200
, pp. 79-87
-
-
Bettelli, E.1
Sullivan, B.2
Szabo, S.J.3
Sobel, R.A.4
Glimcher, L.H.5
Kuchroo, V.K.6
-
24
-
-
13544262333
-
BCL-6 negatively regulates macrophage proliferation by suppressing autocrine IL-6 production
-
Yu, R. Y., X. Wang, F. J. Pixley, J. J. Yu, A. L. Dent, H. E. Broxmeyer, E. R. Stanley, and B. H. Ye. 2005. BCL-6 negatively regulates macrophage proliferation by suppressing autocrine IL-6 production. Blood 105: 1777-1784.
-
(2005)
Blood
, vol.105
, pp. 1777-1784
-
-
Yu, R.Y.1
Wang, X.2
Pixley, F.J.3
Yu, J.J.4
Dent, A.L.5
Broxmeyer, H.E.6
Stanley, E.R.7
Ye, B.H.8
-
25
-
-
82455188362
-
Progenitor expansion in apc mutants is mediated by Jak/Stat signaling
-
Lin, J., X. Wang, and R. I. Dorsky. 2011. Progenitor expansion in apc mutants is mediated by Jak/Stat signaling. BMC Dev. Biol. 11: 73.
-
(2011)
BMC Dev. Biol
, vol.11
, pp. 73
-
-
Lin, J.1
Wang, X.2
Dorsky, R.I.3
-
26
-
-
77955708227
-
Effective targeting of STAT5-mediated survival in myeloproliferative neoplasms using ABT-737 combined with rapamycin
-
Li, G., K. L. Miskimen, Z. Wang, X. Y. Xie, W. Tse, F. Gouilleux, R. Moriggl, and K. D. Bunting. 2010. Effective targeting of STAT5-mediated survival in myeloproliferative neoplasms using ABT-737 combined with rapamycin. Leukemia 24: 1397-1405.
-
(2010)
Leukemia
, vol.24
, pp. 1397-1405
-
-
Li, G.1
Miskimen, K.L.2
Wang, Z.3
Xie, X.Y.4
Tse, W.5
Gouilleux, F.6
Moriggl, R.7
Bunting, K.D.8
-
27
-
-
77956220086
-
TGF-beta induces IL-9 production from human Th17 cells
-
Beriou, G., E. M. Bradshaw, E. Lozano, C. M. Costantino, W. D. Hastings, T. Orban, W. Elyaman, S. J. Khoury, V. K. Kuchroo, C. Baecher-Allan, and D. A. Hafler. 2010. TGF-beta induces IL-9 production from human Th17 cells. J. Immunol. 185: 46-54.
-
(2010)
J. Immunol
, vol.185
, pp. 46-54
-
-
Beriou, G.1
Bradshaw, E.M.2
Lozano, E.3
Costantino, C.M.4
Hastings, W.D.5
Orban, T.6
Elyaman, W.7
Khoury, S.J.8
Kuchroo, V.K.9
Baecher-Allan, C.10
Hafler, D.A.11
-
28
-
-
0028077321
-
IL-9 production of naive CD4+ T cells depends on IL-2, is synergistically enhanced by a combination of TGF-beta and IL-4, and is inhibited by IFN-γamma
-
Schmitt, E., T. Germann, S. Goedert, P. Hoehn, C. Huels, S. Koelsch, R. Kühn, W. Müller, N. Palm, and E. Rüde. 1994. IL-9 production of naive CD4+ T cells depends on IL-2, is synergistically enhanced by a combination of TGF-beta and IL-4, and is inhibited by IFN-γamma. J. Immunol. 153: 3989-3996.
-
(1994)
J. Immunol
, vol.153
, pp. 3989-3996
-
-
Schmitt, E.1
Germann, T.2
Goedert, S.3
Hoehn, P.4
Huels, C.5
Koelsch, S.6
Kühn, R.7
Müller, W.8
Palm, N.9
Rüde, E.10
-
29
-
-
84879355943
-
The signaling suppressor CIS controls proallergic T cell development and allergic airway inflammation
-
Yang, X. O., H. Zhang, B. S. Kim, X. Niu, J. Peng, Y. Chen, R. Kerketta, Y. H. Lee, S. H. Chang, D. B. Corry, et al. 2013. The signaling suppressor CIS controls proallergic T cell development and allergic airway inflammation. Nat. Immunol. 14: 732-740.
-
(2013)
Nat. Immunol
, vol.14
, pp. 732-740
-
-
Yang, X.O.1
Zhang, H.2
Kim, B.S.3
Niu, X.4
Peng, J.5
Chen, Y.6
Kerketta, R.7
Lee, Y.H.8
Chang, S.H.9
Corry, D.B.10
-
30
-
-
84867861268
-
BATF-JUN is critical for IRF4-mediated transcription in T cells
-
Li, P., R. Spolski, W. Liao, L. Wang, T. L. Murphy, K. M. Murphy, and W. J. Leonard. 2012. BATF-JUN is critical for IRF4-mediated transcription in T cells. Nature 490: 543-546.
-
(2012)
Nature
, vol.490
, pp. 543-546
-
-
Li, P.1
Spolski, R.2
Liao, W.3
Wang, L.4
Murphy, T.L.5
Murphy, K.M.6
Leonard, W.J.7
-
31
-
-
84859487740
-
STAT5 protein negatively regulates T follicular helper (Tfh) cell generation and function
-
Nurieva, R. I., A. Podd, Y. Chen, A.M. Alekseev, M. Yu, X. Qi, H. Huang, R.Wen, J. Wang, H. S. Li, et al. 2012. STAT5 protein negatively regulates T follicular helper (Tfh) cell generation and function. J. Biol. Chem. 287: 11234-11239.
-
(2012)
J. Biol. Chem
, vol.287
, pp. 11234-11239
-
-
Nurieva, R.I.1
Podd, A.2
Chen, Y.3
Alekseev, A.M.4
Yu, M.5
Qi, X.6
Huang, H.7
Wen, R.8
Wang, J.9
Li, H.S.10
-
32
-
-
84863116170
-
STAT5 is a potent negative regulator of TFH cell differentiation
-
Johnston, R. J., Y. S. Choi, J. A. Diamond, J. A. Yang, and S. Crotty. 2012. STAT5 is a potent negative regulator of TFH cell differentiation. J. Exp. Med. 209: 243-250.
-
(2012)
J. Exp. Med
, vol.209
, pp. 243-250
-
-
Johnston, R.J.1
Choi, Y.S.2
Diamond, J.A.3
Yang, J.A.4
Crotty, S.5
-
33
-
-
80755172184
-
Opposing signals from the Bcl6 transcription factor and the interleukin-2 receptor generate T helper 1 central and effector memory cells
-
Pepper, M., A. J. Pagán, B. Z. Igyártó, J. J. Taylor, and M. K. Jenkins. 2011. Opposing signals from the Bcl6 transcription factor and the interleukin-2 receptor generate T helper 1 central and effector memory cells. Immunity 35: 583-595.
-
(2011)
Immunity
, vol.35
, pp. 583-595
-
-
Pepper, M.1
Pagán, A.J.2
Igyártó, B.Z.3
Taylor, J.J.4
Jenkins, M.K.5
-
34
-
-
84858706847
-
Molecular mechanisms that control the expression and activity of Bcl-6 in TH1 cells to regulate flexibility with a TFH-like gene profile
-
Oestreich, K. J., S. E. Mohn, and A. S. Weinmann. 2012. Molecular mechanisms that control the expression and activity of Bcl-6 in TH1 cells to regulate flexibility with a TFH-like gene profile. Nat. Immunol. 13: 405-411.
-
(2012)
Nat. Immunol
, vol.13
, pp. 405-411
-
-
Oestreich, K.J.1
Mohn, S.E.2
Weinmann, A.S.3
-
36
-
-
20144369616
-
STAT5 regulates the self-renewal capacity and differentiation of human memory B cells and controls Bcl-6 expression
-
Scheeren, F. A., M. Naspetti, S. Diehl, R. Schotte, M. Nagasawa, E. Wijnands, R. Gimeno, F. A. Vyth-Dreese, B. Blom, and H. Spits. 2005. STAT5 regulates the self-renewal capacity and differentiation of human memory B cells and controls Bcl-6 expression. Nat. Immunol. 6: 303-313.
-
(2005)
Nat. Immunol
, vol.6
, pp. 303-313
-
-
Scheeren, F.A.1
Naspetti, M.2
Diehl, S.3
Schotte, R.4
Nagasawa, M.5
Wijnands, E.6
Gimeno, R.7
Vyth-Dreese, F.A.8
Blom, B.9
Spits, H.10
-
37
-
-
77953494012
-
BCL6 is critical for the development of a diverse primary B cell repertoire
-
Duy, C., J. J. Yu, R. Nahar, S. Swaminathan, S. M. Kweon, J. M. Polo, E. Valls, L. Klemm, S. Shojaee, L. Cerchietti, et al. 2010. BCL6 is critical for the development of a diverse primary B cell repertoire. J. Exp. Med. 207: 1209-1221.
-
(2010)
J. Exp. Med
, vol.207
, pp. 1209-1221
-
-
Duy, C.1
Yu, J.J.2
Nahar, R.3
Swaminathan, S.4
Kweon, S.M.5
Polo, J.M.6
Valls, E.7
Klemm, L.8
Shojaee, S.9
Cerchietti, L.10
-
38
-
-
33846187999
-
STAT5 represses BCL6 expression by binding to a regulatory region frequently mutated in lymphomas
-
Walker, S. R., E. A. Nelson, and D. A. Frank. 2007. STAT5 represses BCL6 expression by binding to a regulatory region frequently mutated in lymphomas. Oncogene 26: 224-233.
-
(2007)
Oncogene
, vol.26
, pp. 224-233
-
-
Walker, S.R.1
Nelson, E.A.2
Frank, D.A.3
-
39
-
-
79955429556
-
Gene interaction network regulates plasma cell differentiation
-
Alinikula, J., and O. Lassila. 2011. Gene interaction network regulates plasma cell differentiation. Scand. J. Immunol. 73: 512-519.
-
(2011)
Scand. J. Immunol
, vol.73
, pp. 512-519
-
-
Alinikula, J.1
Lassila, O.2
-
40
-
-
79961158055
-
Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions
-
Chung, Y., S. Tanaka, F. Chu, R. I. Nurieva, G. J. Martinez, S. Rawal, Y. H. Wang, H. Lim, J. M. Reynolds, X. H. Zhou, et al. 2011. Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions. Nat. Med. 17: 983-988.
-
(2011)
Nat. Med
, vol.17
, pp. 983-988
-
-
Chung, Y.1
Tanaka, S.2
Chu, F.3
Nurieva, R.I.4
Martinez, G.J.5
Rawal, S.6
Wang, Y.H.7
Lim, H.8
Reynolds, J.M.9
Zhou, X.H.10
-
41
-
-
0037100388
-
A putative silencer element in the IL-5 gene recognized by Bcl6
-
Arima, M., H. Toyama, H. Ichii, S. Kojima, S. Okada, M. Hatano, G. Cheng, M. Kubo, T. Fukuda, and T. Tokuhisa. 2002. A putative silencer element in the IL-5 gene recognized by Bcl6. J. Immunol. 169: 829-836.
-
(2002)
J. Immunol
, vol.169
, pp. 829-836
-
-
Arima, M.1
Toyama, H.2
Ichii, H.3
Kojima, S.4
Okada, S.5
Hatano, M.6
Cheng, G.7
Kubo, M.8
Fukuda, T.9
Tokuhisa, T.10
-
42
-
-
51349096042
-
Effects of Th2 pulmonary inflammation in mice with bleomycin-induced pulmonary fibrosis
-
Hirata, H., M. Arima, Y. Fukushima, Y. Ishii, T. Tokuhisa, and T. Fukuda. 2008. Effects of Th2 pulmonary inflammation in mice with bleomycin-induced pulmonary fibrosis. Respirology 13: 788-798.
-
(2008)
Respirology
, vol.13
, pp. 788-798
-
-
Hirata, H.1
Arima, M.2
Fukushima, Y.3
Ishii, Y.4
Tokuhisa, T.5
Fukuda, T.6
-
43
-
-
84255178198
-
Early Th1 cell differentiation is marked by a Tfh cell-like transition
-
Nakayamada, S., Y. Kanno, H. Takahashi, D. Jankovic, K. T. Lu, T. A. Johnson, H. W. Sun, G. Vahedi, O. Hakim, R. Handon, et al. 2011. Early Th1 cell differentiation is marked by a Tfh cell-like transition. Immunity 35: 919-931.
-
(2011)
Immunity
, vol.35
, pp. 919-931
-
-
Nakayamada, S.1
Kanno, Y.2
Takahashi, H.3
Jankovic, D.4
Lu, K.T.5
Johnson, T.A.6
Sun, H.W.7
Vahedi, G.8
Hakim, O.9
Handon, R.10
-
44
-
-
0036695190
-
IL-2 and autoimmune disease
-
Schimpl, A., I. Berberich, B. Kneitz, S. Krämer, B. Santner-Nanan, S. Wagner, M. Wolf, and T. Hünig. 2002. IL-2 and autoimmune disease. Cytokine Growth Factor Rev. 13: 369-378.
-
(2002)
Cytokine Growth Factor Rev
, vol.13
, pp. 369-378
-
-
Schimpl, A.1
Berberich, I.2
Kneitz, B.3
Krämer, S.4
Santner-Nanan, B.5
Wagner, S.6
Wolf, M.7
Hünig, T.8
-
45
-
-
79956085895
-
Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages
-
Liao, W., J. X. Lin, L. Wang, P. Li, and W. J. Leonard. 2011. Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages. Nat. Immunol. 12: 551-559.
-
(2011)
Nat. Immunol
, vol.12
, pp. 551-559
-
-
Liao, W.1
Lin, J.X.2
Wang, L.3
Li, P.4
Leonard, W.J.5
-
46
-
-
54549103162
-
Priming for T helper type 2 differentiation by interleukin 2-mediated induction of interleukin 4 receptor alpha-chain expression
-
Liao, W., D. E. Schones, J. Oh, Y. Cui, K. Cui, T. Y. Roh, K. Zhao, and W. J. Leonard. 2008. Priming for T helper type 2 differentiation by interleukin 2-mediated induction of interleukin 4 receptor alpha-chain expression. Nat. Immunol. 9: 1288-1296.
-
(2008)
Nat. Immunol
, vol.9
, pp. 1288-1296
-
-
Liao, W.1
Schones, D.E.2
Oh, J.3
Cui, Y.4
Cui, K.5
Roh, T.Y.6
Zhao, K.7
Leonard, W.J.8
-
47
-
-
33947162110
-
Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation
-
Laurence, A., C. M. Tato, T. S. Davidson, Y. Kanno, Z. Chen, Z. Yao, R. B. Blank, F. Meylan, R. Siegel, L. Hennighausen, et al. 2007. Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation. Immunity 26: 371-381.
-
(2007)
Immunity
, vol.26
, pp. 371-381
-
-
Laurence, A.1
Tato, C.M.2
Davidson, T.S.3
Kanno, Y.4
Chen, Z.5
Yao, Z.6
Blank, R.B.7
Meylan, F.8
Siegel, R.9
Hennighausen, L.10
-
48
-
-
84861423126
-
Interleukin-2 inhibits germinal center formation by limiting T follicular helper cell differentiation
-
Ballesteros-Tato, A., B. León, B. A. Graf, A. Moquin, P. S. Adams, F. E. Lund, and T. D. Randall. 2012. Interleukin-2 inhibits germinal center formation by limiting T follicular helper cell differentiation. Immunity 36: 847-856.
-
(2012)
Immunity
, vol.36
, pp. 847-856
-
-
Ballesteros-Tato, A.1
León, B.2
Graf, B.A.3
Moquin, A.4
Adams, P.S.5
Lund, F.E.6
Randall, T.D.7
-
49
-
-
0026922358
-
Soluble interleukin-2 receptor and soluble CD8 molecules in cerebrospinal fluid and serum of patients with multiple sclerosis
-
Carrieri, P. B., E. Soscia, B. Iacovitti, M. Pellicano, A. D'Antonio, V. Provitera, and O. Perrella. 1992. Soluble interleukin-2 receptor and soluble CD8 molecules in cerebrospinal fluid and serum of patients with multiple sclerosis. Eur. Cytokine Netw. 3: 495-498.
-
(1992)
Eur. Cytokine Netw
, vol.3
, pp. 495-498
-
-
Carrieri, P.B.1
Soscia, E.2
Iacovitti, B.3
Pellicano, M.4
D'Antonio, A.5
Provitera, V.6
Perrella, O.7
-
50
-
-
63149109244
-
Soluble IL-2RA levels in multiple sclerosis subjects and the effect of soluble IL-2RA on immune responses
-
Maier, L. M., D. E. Anderson, C. A. Severson, C. Baecher-Allan, B. Healy, D. V. Liu, K. D. Wittrup, P. L. De Jager, and D. A. Hafler. 2009. Soluble IL-2RA levels in multiple sclerosis subjects and the effect of soluble IL-2RA on immune responses. J. Immunol. 182: 1541-1547.
-
(2009)
J. Immunol
, vol.182
, pp. 1541-1547
-
-
Maier, L.M.1
Anderson, D.E.2
Severson, C.A.3
Baecher-Allan, C.4
Healy, B.5
Liu, D.V.6
Wittrup, K.D.7
De Jager, P.L.8
Hafler, D.A.9
-
51
-
-
58949100205
-
IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production
-
Maier, L. M., C. E. Lowe, J. Cooper, K. Downes, D. E. Anderson, C. Severson, P. M. Clark, B. Healy, N. Walker, C. Aubin, et al. 2009. IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production. PLoS Genet. 5: e1000322.
-
(2009)
PLoS Genet
, vol.5
-
-
Maier, L.M.1
Lowe, C.E.2
Cooper, J.3
Downes, K.4
Anderson, D.E.5
Severson, C.6
Clark, P.M.7
Healy, B.8
Walker, N.9
Aubin, C.10
-
52
-
-
0026568198
-
IL-2 dependence of IL-9 expression in human T lymphocytes
-
Houssiau, F. A., J. C. Renauld, W. E. Fibbe, and J. Van Snick. 1992. IL-2 dependence of IL-9 expression in human T lymphocytes. J. Immunol. 148: 3147-3151.
-
(1992)
J. Immunol
, vol.148
, pp. 3147-3151
-
-
Houssiau, F.A.1
Renauld, J.C.2
Fibbe, W.E.3
Van Snick, J.4
-
53
-
-
0023696925
-
A novel activation pathway for mature thymocytes: Costimulation of CD2 (T,p50) and CD28 (T,p44) induces autocrine interleukin 2/interleukin 2 receptormediated cell proliferation
-
Yang, S. Y., S. M. Denning, S. Mizuno, B. Dupont, and B. F. Haynes. 1988. A novel activation pathway for mature thymocytes: costimulation of CD2 (T,p50) and CD28 (T,p44) induces autocrine interleukin 2/interleukin 2 receptormediated cell proliferation. J. Exp. Med. 168: 1457-1468.
-
(1988)
J. Exp. Med
, vol.168
, pp. 1457-1468
-
-
Yang, S.Y.1
Denning, S.M.2
Mizuno, S.3
Dupont, B.4
Haynes, B.F.5
-
54
-
-
0028286628
-
Cytoplasmic domains of the interleukin-2 receptor beta and gamma chains mediate the signal for T-cell proliferation
-
Nelson, B. H., J. D. Lord, and P. D. Greenberg. 1994. Cytoplasmic domains of the interleukin-2 receptor beta and gamma chains mediate the signal for T-cell proliferation. Nature 369: 333-336.
-
(1994)
Nature
, vol.369
, pp. 333-336
-
-
Nelson, B.H.1
Lord, J.D.2
Greenberg, P.D.3
-
55
-
-
0028171065
-
Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: Implications for XSCID and XCID
-
Russell, S. M., J. A. Johnston, M. Noguchi, M. Kawamura, C. M. Bacon, M. Friedmann, M. Berg, D. W. McVicar, B. A. Witthuhn, O. Silvennoinen, et al. 1994. Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID. Science 266: 1042-1045.
-
(1994)
Science
, vol.266
, pp. 1042-1045
-
-
Russell, S.M.1
Johnston, J.A.2
Noguchi, M.3
Kawamura, M.4
Bacon, C.M.5
Friedmann, M.6
Berg, M.7
McVicar, D.W.8
Witthuhn, B.A.9
Silvennoinen, O.10
-
56
-
-
0035925887
-
Signaling domains of the interleukin 2 receptor
-
Gaffen, S. L. 2001. Signaling domains of the interleukin 2 receptor. Cytokine 14: 63-77.
-
(2001)
Cytokine
, vol.14
, pp. 63-77
-
-
Gaffen, S.L.1
-
57
-
-
0032827421
-
Transcriptional repression of Stat6-dependent interleukin-4-induced genes by BCL-6: Specific regulation of Iε transcription and immunoglobulin e switching
-
Harris, M. B., C. C. Chang, M. T. Berton, N. N. Danial, J. Zhang, D. Kuehner, B. H. Ye, M. Kvatyuk, P. P. Pandolfi, G. Cattoretti, et al. 1999. Transcriptional repression of Stat6-dependent interleukin-4-induced genes by BCL-6: specific regulation of Iε transcription and immunoglobulin E switching. Mol. Cell. Biol. 19: 7264-7275.
-
(1999)
Mol. Cell. Biol
, vol.19
, pp. 7264-7275
-
-
Harris, M.B.1
Chang, C.C.2
Berton, M.T.3
Danial, N.N.4
Zhang, J.5
Kuehner, D.6
Ye, B.H.7
Kvatyuk, M.8
Pandolfi, P.P.9
Cattoretti, G.10
-
58
-
-
44449145063
-
STAT3-mediated up-regulation of BLIMP1 is coordinated with BCL6 down-regulation to control human plasma cell differentiation
-
Diehl, S. A., H. Schmidlin, M. Nagasawa, S. D. van Haren, M. J. Kwakkenbos, E. Yasuda, T. Beaumont, F. A. Scheeren, and H. Spits. 2008. STAT3-mediated up-regulation of BLIMP1 is coordinated with BCL6 down-regulation to control human plasma cell differentiation. J. Immunol. 180: 4805-4815.
-
(2008)
J. Immunol
, vol.180
, pp. 4805-4815
-
-
Diehl, S.A.1
Schmidlin, H.2
Nagasawa, M.3
Van Haren, S.D.4
Kwakkenbos, M.J.5
Yasuda, E.6
Beaumont, T.7
Scheeren, F.A.8
Spits, H.9
-
59
-
-
34447634411
-
Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch
-
Amsen, D., A. Antov, D. Jankovic, A. Sher, F. Radtke, A. Souabni, M. Busslinger, B. McCright, T. Gridley, and R. A. Flavell. 2007. Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch. Immunity 27: 89-99.
-
(2007)
Immunity
, vol.27
, pp. 89-99
-
-
Amsen, D.1
Antov, A.2
Jankovic, D.3
Sher, A.4
Radtke, F.5
Souabni, A.6
Busslinger, M.7
McCright, B.8
Gridley, T.9
Flavell, R.A.10
-
60
-
-
34447642439
-
Notch directly regulates Gata3 expression during T helper 2 cell differentiation
-
Fang, T. C., Y. Yashiro-Ohtani, C. Del Bianco, D. M. Knoblock, S. C. Blacklow, and W. S. Pear. 2007. Notch directly regulates Gata3 expression during T helper 2 cell differentiation. Immunity 27: 100-110.
-
(2007)
Immunity
, vol.27
, pp. 100-110
-
-
Fang, T.C.1
Yashiro-Ohtani, Y.2
Del Bianco, C.3
Knoblock, D.M.4
Blacklow, S.C.5
Pear, W.S.6
-
61
-
-
84869806031
-
IFN-γ limits Th9-mediated autoimmune inflammation through dendritic cell modulation of IL-27
-
Murugaiyan, G., V. Beynon, A. Pires Da Cunha, N. Joller, and H. L. Weiner. 2012. IFN-γ limits Th9-mediated autoimmune inflammation through dendritic cell modulation of IL-27. J. Immunol. 189: 5277-5283.
-
(2012)
J. Immunol
, vol.189
, pp. 5277-5283
-
-
Murugaiyan, G.1
Beynon, V.2
Pires Da Cunha, A.3
Joller, N.4
Weiner, H.L.5
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