메뉴 건너뛰기




Volumn 150, Issue 8, 2009, Pages 3645-3654

Computational and functional analysis of growth hormone (GH)-regulated genes identifies the transcriptional repressor B-cell lymphoma 6 (Bc16) as a participant in GH-regulated transcription

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL 6; PROTEIN SH2; PROTEIN SUBUNIT; SOMATOMEDIN C; STAT5 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 2;

EID: 67651162130     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2009-0212     Document Type: Article
Times cited : (27)

References (74)
  • 3
    • 0006789567 scopus 로고
    • Regulation of insulin-like growth factor I gene expression by growth hormone
    • Mathews LS, Norstedt G, Palmiter RD 1986 Regulation of insulin-like growth factor I gene expression by growth hormone. Proc Nat Acad Sci USA 83:9343-9347
    • (1986) Proc Nat Acad Sci USA , vol.83 , pp. 9343-9347
    • Mathews, L.S.1    Norstedt, G.2    Palmiter, R.D.3
  • 4
    • 0037590103 scopus 로고    scopus 로고
    • Acute control of insulin-like growth factor-I gene transcription by growth hormone through Stat5b
    • Woelfle J, Billiard J, Rotwein P 2003 Acute control of insulin-like growth factor-I gene transcription by growth hormone through Stat5b. J Biol Chem 278:22696-22702
    • (2003) J Biol Chem , vol.278 , pp. 22696-22702
    • Woelfle, J.1    Billiard, J.2    Rotwein, P.3
  • 5
    • 0028180418 scopus 로고
    • Growth hormone (GH) regulation of a rat serine protease inhibitor fusion gene in cells transfected with GH receptor cDNA
    • Enberg B, Hulthén A, Möller C, Norstedt G, Francis SM 1994 Growth hormone (GH) regulation of a rat serine protease inhibitor fusion gene in cells transfected with GH receptor cDNA. J Mol Endocrinol 12:39-46
    • (1994) J Mol Endocrinol , vol.12 , pp. 39-46
    • Enberg, B.1    Hulthén, A.2    Möller, C.3    Norstedt, G.4    Francis, S.M.5
  • 7
    • 0024600686 scopus 로고
    • Growth hormone stimulates c-fos gene expression by means of protein kinase C without increasing inositol lipid turnover
    • Doglio A, Dani C, Grimaldi P, Ailhaud G 1989 Growth hormone stimulates c-fos gene expression by means of protein kinase C without increasing inositol lipid turnover. Proc Natl Acad Sci USA 86:1148-1152
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 1148-1152
    • Doglio, A.1    Dani, C.2    Grimaldi, P.3    Ailhaud, G.4
  • 8
    • 0026707675 scopus 로고
    • Sex-specific, growth hormone-regulated transcription of the cytochrome P450 2C11 and 2C12 genes
    • Sundseth SS, Alberta JA, Waxman DJ 1992 Sex-specific, growth hormone-regulated transcription of the cytochrome P450 2C11 and 2C12 genes. J Biol Chem 267:3907-3914
    • (1992) J Biol Chem , vol.267 , pp. 3907-3914
    • Sundseth, S.S.1    Alberta, J.A.2    Waxman, D.J.3
  • 9
    • 33744456856 scopus 로고    scopus 로고
    • Growth hormone regulation of sex-dependent liver gene expression
    • Waxman DJ, O'Connor C 2006 Growth hormone regulation of sex-dependent liver gene expression. Mol Endocrinol 20:2613-2629
    • (2006) Mol Endocrinol , vol.20 , pp. 2613-2629
    • Waxman, D.J.1    O'Connor, C.2
  • 10
    • 0025678937 scopus 로고
    • Rapid events in growth hormone action. Induction of c-fos and c-jun transcription in 3T3-F442A preadipocytes
    • Gurland G, Ashcom G, Cochran BH, Schwartz J 1990 Rapid events in growth hormone action. Induction of c-fos and c-jun transcription in 3T3-F442A preadipocytes. Endocrinology 127:3187-3195
    • (1990) Endocrinology , vol.127 , pp. 3187-3195
    • Gurland, G.1    Ashcom, G.2    Cochran, B.H.3    Schwartz, J.4
  • 11
    • 33846243715 scopus 로고
    • Hypophysectomie et diabete pancreatique chez le crapaud.
    • Houssay BA, Biasotti A 1930 Hypophysectomie et diabete pancreatique chez le crapaud. C R Soc Biol (Paris) 104:407-412
    • (1930) C R Soc Biol (Paris) , vol.104 , pp. 407-412
    • Houssay, B.A.1    Biasotti, A.2
  • 12
    • 0036521760 scopus 로고    scopus 로고
    • Growth hormone-induced alterations in the insulin-signaling system
    • Dominici FP, Turyn D 2002 Growth hormone-induced alterations in the insulin-signaling system. Exp Biol Med (Maywood) 227:149-157
    • (2002) Exp Biol Med (Maywood) , vol.227 , pp. 149-157
    • Dominici, F.P.1    Turyn, D.2
  • 13
    • 0023336083 scopus 로고
    • Effect of growth hormone on carbohydrate and lipid metabolism
    • Davidson MB 1987 Effect of growth hormone on carbohydrate and lipid metabolism. Endocr Rev 8:115-131
    • (1987) Endocr Rev , vol.8 , pp. 115-131
    • Davidson, M.B.1
  • 16
    • 33645213704 scopus 로고    scopus 로고
    • Huo JS, McEachin RC, Cui TX, Duggal NK, Hai T, States DJ, Schwartz J 2006 Profiles of growth hormone (GH)-regulated genes reveal time-dependent responses and identify a mechanism for regulation of activating transcription factor 3 by GH. J Biol Chem 281:4132-4141
    • Huo JS, McEachin RC, Cui TX, Duggal NK, Hai T, States DJ, Schwartz J 2006 Profiles of growth hormone (GH)-regulated genes reveal time-dependent responses and identify a mechanism for regulation of activating transcription factor 3 by GH. J Biol Chem 281:4132-4141
  • 20
    • 0033982936 scopus 로고    scopus 로고
    • KEGG: Kyoto encyclopedia of genes and genomes
    • Kanehisa M, Goto S 2000 KEGG: Kyoto encyclopedia of genes and genomes. Nucleic Acids Res 28:27-30
    • (2000) Nucleic Acids Res , vol.28 , pp. 27-30
    • Kanehisa, M.1    Goto, S.2
  • 22
    • 33747830882 scopus 로고    scopus 로고
    • Clustering microarray gene expression data using weighted Chinese restaurant process
    • Qin ZS 2006 Clustering microarray gene expression data using weighted Chinese restaurant process. Bioinformatics 22:1988-1997
    • (2006) Bioinformatics , vol.22 , pp. 1988-1997
    • Qin, Z.S.1
  • 23
    • 33748460087 scopus 로고    scopus 로고
    • Foxp3-dependent and -independent molecules specific for CD25+CD4+ natural regulatory T cells revealed by DNA microarray analysis
    • Sugimoto N, Oida T, Hirota K, Nakamura K, Nomura T, Uchiyama T, Sakaguchi S 2006 Foxp3-dependent and -independent molecules specific for CD25+CD4+ natural regulatory T cells revealed by DNA microarray analysis. Int Immunol 18:1197-1209
    • (2006) Int Immunol , vol.18 , pp. 1197-1209
    • Sugimoto, N.1    Oida, T.2    Hirota, K.3    Nakamura, K.4    Nomura, T.5    Uchiyama, T.6    Sakaguchi, S.7
  • 24
  • 26
    • 0034871380 scopus 로고    scopus 로고
    • Differential gene expression in response to methoxychlor and estradiol through ERα, ERβ, and AR in reproductive tissues of female mice
    • Waters KM, Safe S, Gaido KW 2001 Differential gene expression in response to methoxychlor and estradiol through ERα, ERβ, and AR in reproductive tissues of female mice. Toxicol Sci 63:47-56
    • (2001) Toxicol Sci , vol.63 , pp. 47-56
    • Waters, K.M.1    Safe, S.2    Gaido, K.W.3
  • 27
    • 0033615595 scopus 로고    scopus 로고
    • CCAAT/enhancer-binding protein β (C/EBPβ) and C/EBPδ contribute to growth hormone-regulated transcription of c-fos
    • Liao J, Piwien-Pilipuk G, Ross SE, Hodge CL, Sealy L, MacDougald OA, Schwartz J 1999 CCAAT/enhancer-binding protein β (C/EBPβ) and C/EBPδ contribute to growth hormone-regulated transcription of c-fos. J Biol Chem 274:31597-31604
    • (1999) J Biol Chem , vol.274 , pp. 31597-31604
    • Liao, J.1    Piwien-Pilipuk, G.2    Ross, S.E.3    Hodge, C.L.4    Sealy, L.5    MacDougald, O.A.6    Schwartz, J.7
  • 28
    • 33847724385 scopus 로고    scopus 로고
    • CCAAT/enhancer-binding protein (C/EBP) β is acetylated at multiple lysines: Acetylation of C/EBPβ at lysine 39 modulates its ability to activate transcription
    • Ceseña TI, Cardinaux JR, Kwok R, Schwartz J 2007 CCAAT/enhancer-binding protein (C/EBP) β is acetylated at multiple lysines: acetylation of C/EBPβ at lysine 39 modulates its ability to activate transcription. J Biol Chem 282:956-967
    • (2007) J Biol Chem , vol.282 , pp. 956-967
    • Ceseña, T.I.1    Cardinaux, J.R.2    Kwok, R.3    Schwartz, J.4
  • 31
    • 0027478579 scopus 로고
    • Growth hormone-promoted tyrosyl phosphorylation of a 121-kDa growth hormone receptor-associated protein
    • Wang X, Möller C, Norstedt G, Carter-Su C 1993 Growth hormone-promoted tyrosyl phosphorylation of a 121-kDa growth hormone receptor-associated protein. J Biol Chem 268:3573-3579
    • (1993) J Biol Chem , vol.268 , pp. 3573-3579
    • Wang, X.1    Möller, C.2    Norstedt, G.3    Carter-Su, C.4
  • 32
    • 0037113978 scopus 로고    scopus 로고
    • Dual regulation of phosphorylation and dephosphorylation of C/EBPβ modulate its transcriptional activation and DNA binding in response to growth hormone
    • Piwien-Pilipuk G, MacDougald O, Schwartz J 2002 Dual regulation of phosphorylation and dephosphorylation of C/EBPβ modulate its transcriptional activation and DNA binding in response to growth hormone. J Biol Chem 277:44557-44565
    • (2002) J Biol Chem , vol.277 , pp. 44557-44565
    • Piwien-Pilipuk, G.1    MacDougald, O.2    Schwartz, J.3
  • 33
    • 23744455019 scopus 로고    scopus 로고
    • Endogenous CCAAT/enhancer binding protein β and p300 are both regulated by growth hormone to mediate transcriptional activation
    • Cui TX, Piwien-Pilipuk G, Huo JS, Kaplani J, Kwok R, Schwartz J 2005 Endogenous CCAAT/enhancer binding protein β and p300 are both regulated by growth hormone to mediate transcriptional activation. Mol Endocrinol 19:2175-2186
    • (2005) Mol Endocrinol , vol.19 , pp. 2175-2186
    • Cui, T.X.1    Piwien-Pilipuk, G.2    Huo, J.S.3    Kaplani, J.4    Kwok, R.5    Schwartz, J.6
  • 35
    • 0021894457 scopus 로고
    • Mode of action of pituitary growth hormone on target cells
    • Isaksson OG, Edén S, Jansson JO 1985 Mode of action of pituitary growth hormone on target cells. Annu Rev Physiol 47:483-499
    • (1985) Annu Rev Physiol , vol.47 , pp. 483-499
    • Isaksson, O.G.1    Edén, S.2    Jansson, J.O.3
  • 37
    • 1442300760 scopus 로고    scopus 로고
    • In vivo regulation of growth hormone-stimulated gene transcription by STAT5b
    • Woelfle J, Rotwein P 2004 In vivo regulation of growth hormone-stimulated gene transcription by STAT5b. Am J Physiol Endocrinol Metab 286:E393-E401
    • (2004) Am J Physiol Endocrinol Metab , vol.286
    • Woelfle, J.1    Rotwein, P.2
  • 38
    • 0033304728 scopus 로고    scopus 로고
    • Growth hormone regulation of SOCS-2, SOCS-3, and CIS messenger ribonucleic acid expression in the rat
    • Tollet-Egnell P, Flores-Morales A, Stavréus-Evers A, Sahlin L, Norstedt G 1999 Growth hormone regulation of SOCS-2, SOCS-3, and CIS messenger ribonucleic acid expression in the rat. Endocrinology 140:3693-3704
    • (1999) Endocrinology , vol.140 , pp. 3693-3704
    • Tollet-Egnell, P.1    Flores-Morales, A.2    Stavréus-Evers, A.3    Sahlin, L.4    Norstedt, G.5
  • 40
    • 33846187999 scopus 로고    scopus 로고
    • STAT5 represses BCL6 expression by binding to a regulatory region frequently mutated in lymphomas
    • Walker SR, Nelson EA, Frank DA 2007 STAT5 represses BCL6 expression by binding to a regulatory region frequently mutated in lymphomas. Oncogene 26:224-233
    • (2007) Oncogene , vol.26 , pp. 224-233
    • Walker, S.R.1    Nelson, E.A.2    Frank, D.A.3
  • 43
  • 44
    • 0032536744 scopus 로고    scopus 로고
    • Cyclic AMP potentiates growth hormone-dependent differentiation of 3T3-F442A preadipocytes: Possible involvement of the transcription factor CREB
    • Yarwood SJ, Kilgour E, Anderson NG 1998 Cyclic AMP potentiates growth hormone-dependent differentiation of 3T3-F442A preadipocytes: possible involvement of the transcription factor CREB. Mol Cell Endocrinol 138:41-50
    • (1998) Mol Cell Endocrinol , vol.138 , pp. 41-50
    • Yarwood, S.J.1    Kilgour, E.2    Anderson, N.G.3
  • 45
    • 38849099855 scopus 로고    scopus 로고
    • Cooperative regulation of endogenous cAMP-response element binding protein and CCAAT/enhancer-binding protein β in GH-stimulated c-fos expression
    • Cui TX, Kwok R, Schwartz J 2008 Cooperative regulation of endogenous cAMP-response element binding protein and CCAAT/enhancer-binding protein β in GH-stimulated c-fos expression. J Endocrinol 196:89-100
    • (2008) J Endocrinol , vol.196 , pp. 89-100
    • Cui, T.X.1    Kwok, R.2    Schwartz, J.3
  • 46
    • 13944251646 scopus 로고    scopus 로고
    • Role of SOCS2 in growth hormone actions
    • Turnley AM 2005 Role of SOCS2 in growth hormone actions. Trends Endocrinol Metab 16:53-58
    • (2005) Trends Endocrinol Metab , vol.16 , pp. 53-58
    • Turnley, A.M.1
  • 47
    • 0034801684 scopus 로고    scopus 로고
    • SOCS proteins: Negative regulators of cytokine signaling
    • Krebs DL, Hilton DJ 2001 SOCS proteins: negative regulators of cytokine signaling. Stem Cells 19:378-387
    • (2001) Stem Cells , vol.19 , pp. 378-387
    • Krebs, D.L.1    Hilton, D.J.2
  • 48
    • 33846787037 scopus 로고    scopus 로고
    • The BCL6 proto-oncogene: A leading role during germinal center development and lymphomagenesis
    • Jardin F, Ruminy P, Bastard C, Tilly H 2007 The BCL6 proto-oncogene: a leading role during germinal center development and lymphomagenesis. Pathol Biol (Paris) 55:73-83
    • (2007) Pathol Biol (Paris) , vol.55 , pp. 73-83
    • Jardin, F.1    Ruminy, P.2    Bastard, C.3    Tilly, H.4
  • 49
    • 47149096182 scopus 로고    scopus 로고
    • B-cell lymphoma 6 and the molecular pathogenesis of diffuse large B-cell lymphoma
    • Ci W, Polo JM, Melnick A 2008 B-cell lymphoma 6 and the molecular pathogenesis of diffuse large B-cell lymphoma. Curr Opin Hematol 15:381-390
    • (2008) Curr Opin Hematol , vol.15 , pp. 381-390
    • Ci, W.1    Polo, J.M.2    Melnick, A.3
  • 50
    • 0032538429 scopus 로고    scopus 로고
    • Components of the SMRT corepressor complex exhibit distinctive interactions with the POZ domain oncoproteins PLZF, PLZF-RARα, and BCL-6
    • Wong CW, Privalsky ML 1998 Components of the SMRT corepressor complex exhibit distinctive interactions with the POZ domain oncoproteins PLZF, PLZF-RARα, and BCL-6. J Biol Chem 273:27695-27702
    • (1998) J Biol Chem , vol.273 , pp. 27695-27702
    • Wong, C.W.1    Privalsky, M.L.2
  • 51
    • 0032511890 scopus 로고    scopus 로고
    • The BCL-6 POZ domain and other POZ domains interact with the co-repressors N-CoR and SMRT
    • Huynh KD, Bardwell VJ 1998 The BCL-6 POZ domain and other POZ domains interact with the co-repressors N-CoR and SMRT. Oncogene 17:2473-2484
    • (1998) Oncogene , vol.17 , pp. 2473-2484
    • Huynh, K.D.1    Bardwell, V.J.2
  • 52
    • 0034661112 scopus 로고    scopus 로고
    • BCoR, a novel corepressor involved in BCL-6 repression
    • Huynh KD, Fischle W, Verdin E, Bardwell VJ 2000 BCoR, a novel corepressor involved in BCL-6 repression. Genes Dev 14:1810-1823
    • (2000) Genes Dev , vol.14 , pp. 1810-1823
    • Huynh, K.D.1    Fischle, W.2    Verdin, E.3    Bardwell, V.J.4
  • 57
    • 34250800195 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription (Stat) 5b-mediated inhibition of insulin-like growth factor binding protein-1 gene transcription: A mechanism for repression of gene expression by growth hormone
    • Ono M, Chia DJ, Merino-Martinez R, Flores-Morales A, Unterman TG, Rotwein P 2007 Signal transducer and activator of transcription (Stat) 5b-mediated inhibition of insulin-like growth factor binding protein-1 gene transcription: a mechanism for repression of gene expression by growth hormone. Mol Endocrinol 21:1443-1457
    • (2007) Mol Endocrinol , vol.21 , pp. 1443-1457
    • Ono, M.1    Chia, D.J.2    Merino-Martinez, R.3    Flores-Morales, A.4    Unterman, T.G.5    Rotwein, P.6
  • 58
    • 48249150036 scopus 로고    scopus 로고
    • Sex-specific early growth hormone response genes in rat liver
    • Wauthier V, Waxman DJ 2008 Sex-specific early growth hormone response genes in rat liver. Mol Endocrinol 22:1962-1974
    • (2008) Mol Endocrinol , vol.22 , pp. 1962-1974
    • Wauthier, V.1    Waxman, D.J.2
  • 59
    • 33344457703 scopus 로고    scopus 로고
    • Codependence of growth hormone-responsive, sexually dimorphic hepatic gene expression on signal transducer and activator of transcription 5b and hepatic nuclear factor 4α
    • Holloway MG, Laz EV, Waxman DJ 2006 Codependence of growth hormone-responsive, sexually dimorphic hepatic gene expression on signal transducer and activator of transcription 5b and hepatic nuclear factor 4α. Mol Endocrinol 20:647-660
    • (2006) Mol Endocrinol , vol.20 , pp. 647-660
    • Holloway, M.G.1    Laz, E.V.2    Waxman, D.J.3
  • 61
    • 11144241637 scopus 로고    scopus 로고
    • Isolation of unique STAT5 targets by chromatin immunoprecipitation-based gene identification
    • Nelson EA, Walker SR, Alvarez JV, Frank DA 2004 Isolation of unique STAT5 targets by chromatin immunoprecipitation-based gene identification. J Biol Chem 279:54724-54730
    • (2004) J Biol Chem , vol.279 , pp. 54724-54730
    • Nelson, E.A.1    Walker, S.R.2    Alvarez, J.V.3    Frank, D.A.4
  • 62
    • 0036898253 scopus 로고    scopus 로고
    • Acetylation inactivates the transcriptional repressor BCL6
    • Bereshchenko OR, Gu W, Dalla-Favera R 2002 Acetylation inactivates the transcriptional repressor BCL6. Nat Genet 32:606-613
    • (2002) Nat Genet , vol.32 , pp. 606-613
    • Bereshchenko, O.R.1    Gu, W.2    Dalla-Favera, R.3
  • 63
    • 0032128002 scopus 로고    scopus 로고
    • Antigen receptor signaling induces MAP kinase-mediated phosphorylation and degradation of the BCL-6 transcription factor
    • Niu H, Ye BH, Dalla-Favera R 1998 Antigen receptor signaling induces MAP kinase-mediated phosphorylation and degradation of the BCL-6 transcription factor. Genes Dev 12:1953-1961
    • (1998) Genes Dev , vol.12 , pp. 1953-1961
    • Niu, H.1    Ye, B.H.2    Dalla-Favera, R.3
  • 68
    • 0030901289 scopus 로고    scopus 로고
    • Control of inflammation, cytokine expression, and germinal center formation by BCL-6
    • Dent AL, Shaffer AL, Yu X, Allman D, Staudt LM 1997 Control of inflammation, cytokine expression, and germinal center formation by BCL-6. Science 276:589-592
    • (1997) Science , vol.276 , pp. 589-592
    • Dent, A.L.1    Shaffer, A.L.2    Yu, X.3    Allman, D.4    Staudt, L.M.5
  • 70
    • 21344434092 scopus 로고    scopus 로고
    • The regulation of fatty acid synthase by STAT5A
    • Hogan JC, Stephens JM 2005 The regulation of fatty acid synthase by STAT5A. Diabetes 54:1968-1975
    • (2005) Diabetes , vol.54 , pp. 1968-1975
    • Hogan, J.C.1    Stephens, J.M.2
  • 71
    • 34249742693 scopus 로고    scopus 로고
    • The STAT5A-mediated induction of pyruvate dehydrogenase kinase 4 expression by prolactin or growth hormone in adipocytes
    • White UA, Coulter AA, Miles TK, Stephens JM 2007 The STAT5A-mediated induction of pyruvate dehydrogenase kinase 4 expression by prolactin or growth hormone in adipocytes. Diabetes 56:1623-1629
    • (2007) Diabetes , vol.56 , pp. 1623-1629
    • White, U.A.1    Coulter, A.A.2    Miles, T.K.3    Stephens, J.M.4
  • 72
    • 0346849704 scopus 로고    scopus 로고
    • Constitutively active signal transducer and activator of transcription 5 can replace the requirement for growth hormone in adipogenesis of 3T3-F442A preadipocytes
    • Shang CA, Waters MJ 2003 Constitutively active signal transducer and activator of transcription 5 can replace the requirement for growth hormone in adipogenesis of 3T3-F442A preadipocytes. Mol Endocrinol 17:2494-2508
    • (2003) Mol Endocrinol , vol.17 , pp. 2494-2508
    • Shang, C.A.1    Waters, M.J.2
  • 73
    • 33847684669 scopus 로고    scopus 로고
    • Growth hormone stimulates adipogenesis of 3T3-L1 cells through activation of the Stat5A/5B-PPARγ pathway
    • Kawai M, Namba N, Mushiake S, Etani Y, Nishimura R, Makishima M, Ozono K 2007 Growth hormone stimulates adipogenesis of 3T3-L1 cells through activation of the Stat5A/5B-PPARγ pathway. J Mol Endocrinol 38:19-34
    • (2007) J Mol Endocrinol , vol.38 , pp. 19-34
    • Kawai, M.1    Namba, N.2    Mushiake, S.3    Etani, Y.4    Nishimura, R.5    Makishima, M.6    Ozono, K.7
  • 74
    • 0023678685 scopus 로고
    • Effects of human growth hormone on insulin-stimulated glucose metabolism in 3T3-F442A adipocytes
    • Foster CM, Hale PM, Jing HW, Schwartz J 1988 Effects of human growth hormone on insulin-stimulated glucose metabolism in 3T3-F442A adipocytes. Endocrinology 123:1082-1088
    • (1988) Endocrinology , vol.123 , pp. 1082-1088
    • Foster, C.M.1    Hale, P.M.2    Jing, H.W.3    Schwartz, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.