The Ras-related protein, Rap1A, mediates thrombin-stimulated, integrin-dependent glioblastoma cell proliferation and tumor growth

Journal of Biological Chemistry

Volumn 289, Issue 25, 2014, Pages 17689-17698

  Sayyah, Jacqueline ^a   Bartakova, Alena ^b   Nogal, Nekeisha ^a   Quilliam, Lawrence A ^c   Stupack, Dwayne G ^b   Brown, Joan Heller ^a  

^a San Diego   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c INDIANA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ANTIBODIES; CELL ADHESION; CELL PROLIFERATION; CELLS; CHEMICAL ACTIVATION; PROGRAMMABLE LOGIC CONTROLLERS; TUMORS;

ADHESION KINASE; G PROTEIN COUPLED RECEPTORS; GLIOBLASTOMA CELLS; INTEGRIN ACTIVATION; NEUTRALIZING ANTIBODIES; PHOSPHOLIPASE D; RAS-RELATED PROTEINS; TUMOR FORMATION;

ENZYMES;

BETA1 INTEGRIN; FIBRONECTIN; FOCAL ADHESION KINASE; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR PAR 1; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHOLIPASE D; RAP1 PROTEIN; RAP1A PROTEIN; RAP1B PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; THROMBIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CELL ADHESION; CELL PROLIFERATION; CELL STIMULATION; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE ASSOCIATION; DOWN REGULATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENE SILENCING; GLIOBLASTOMA; GLIOBLASTOMA CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; TUMOR GROWTH; TUMOR VOLUME; TUMOR XENOGRAFT;

CELL PROLIFERATION; CELL SIGNALING; G-PROTEIN-COUPLED RECEPTOR (GPCR); GLIOBLASTOMA; INTEGRIN; RAP1; SMALL GTPASE; THROMBIN;

ANIMALS; ANTIGENS, CD29; CELL LINE, TUMOR; CELL PROLIFERATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOBLASTOMA; HETEROGRAFTS; HUMANS; MICE; NEOPLASM PROTEINS; NEOPLASM TRANSPLANTATION; RAP1 GTP-BINDING PROTEINS; RHOA GTP-BINDING PROTEIN; THROMBIN;

EID: 84903436107     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.536227     Document Type: Article

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