CalDAG-GEFI and protein kinase C represent alternative pathways leading to activation of integrin αIIbβ3 in platelets

Blood

Volumn 112, Issue 5, 2008, Pages 1696-1703

  Cifuni, Stephen M ^a   Wagner, Denisa D ^a   Bergmeier, Wolfgang ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA2 INTEGRIN; CALCIUM ION; DIACYLGLYCEROL REGULATED QUANINE NUCLEOTIDE EXCHANGE FACTOR 1; GUANOSINE TRIPHOSPHATASE; INTEGRIN ALPHA2B BETA13; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; RAP1 PROTEIN; UNCLASSIFIED DRUG; ADENOSINE DIPHOSPHATE; FIBRINOGEN RECEPTOR; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GYPGKF NH(2); GYPGKF-NH(2); INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; OLIGOPEPTIDE; PROTEASE-ACTIVATED RECEPTOR 4; PROTEINASE ACTIVATED RECEPTOR 4; RASGRP2 PROTEIN, MOUSE; THROMBIN RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FLOW CYTOMETRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEROTONIN RELEASE; SIGNAL TRANSDUCTION; THROMBOCYTE AGGREGATION; ANIMAL; BIOLOGICAL MODEL; BLOOD; DEGRANULATION; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; KINETICS; METABOLISM; MOUSE MUTANT; PHYSIOLOGY; THROMBOCYTE;

ADENOSINE DIPHOSPHATE; ANIMALS; BLOOD PLATELETS; CELL DEGRANULATION; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; GUANINE NUCLEOTIDE EXCHANGE FACTORS; KINETICS; MICE; MICE, KNOCKOUT; MODELS, BIOLOGICAL; OLIGOPEPTIDES; PLATELET AGGREGATION; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PROTEIN KINASE C; RAP1 GTP-BINDING PROTEINS; RECEPTORS, THROMBIN; SIGNAL TRANSDUCTION;

EID: 52649163308     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2008-02-139733     Document Type: Article

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