Polyphenol-rich strawberry extract protects human dermal fibroblasts against hydrogen peroxide oxidative damage and improves mitochondrial functionality

Molecules

Volumn 19, Issue 6, 2014, Pages 7798-7816

  Giampieri, Francesca ^a   Alvarez Suarez, José M ^a,d   Mazzoni, Luca ^a   Forbes Hernandez, Tamara Y ^a,d   Gasparrini, Massimiliano ^a   Gonzàlez Paramàs, Ana M ^b   Santos Buelga, Celestino ^b   Quiles, José L ^c   Bompadre, Stefano ^a   Mezzetti, Bruno ^a   Battino, Maurizio ^a,e  

^a UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^b UNIVERSITY OF SALAMANCA   (Spain)

^c UNIVERSITY OF GRANADA   (Spain)

^d Area de Nutrición y Salud Universidad Internacional Iberoamericana UNINI   (Mexico)

^e Parque Científico y Tecnológico de Cantabria   (Spain)

Author keywords

Anthocyanin; DNA damage; Fibroblasts; Lipid peroxidation; ROS; Strawberry

Indexed keywords

ANTHOCYANIN; ANTIOXIDANT; ASCORBIC ACID; BETA CAROTENE; FLAVONOID; HYDROGEN PEROXIDE; OLIGOMYCIN; PHENOL; PLANT EXTRACT;

CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; CYTOLOGY; DERMIS; DNA DAMAGE; DRUG EFFECTS; FIBROBLAST; FRAGARIA; HUMAN; LIPID PEROXIDATION; METABOLISM; MITOCHONDRION; OXYGEN CONSUMPTION;

ANTHOCYANINS; ANTIOXIDANTS; ASCORBIC ACID; BETA CAROTENE; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; DERMIS; DNA DAMAGE; FIBROBLASTS; FLAVONOIDS; FRAGARIA; HUMANS; HYDROGEN PEROXIDE; LIPID PEROXIDATION; MITOCHONDRIA; OLIGOMYCINS; OXYGEN CONSUMPTION; PHENOL; PLANT EXTRACTS;

EID: 84903291432     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules19067798     Document Type: Article

References (37)

1. Giamp ieri, F.; Alvarez-Suarez, J.M.; Tulipani, S.; Gonzalez-Paramas, A.M.; Santos-Buelga, C.; Bompadre, S.; Quiles, J.L.; Mezzetti, B.; Battino, M. Photoprotective potential of strawberry (Fragaria × ananassa) extract against UV-A irradiation damage on human fibroblasts. J. Agric. Food Chem. 2012, 60, 2322-2327.
2. Oyewole, A.O.; Wilmot, M.C.; Fowler, M.; Birch-Machin, M.A. Comparing the effects of mitochondrial targete d and localized antioxidants with cellular antioxidants in human skin cells exposed to UVA and hydrogen peroxide. FASEB J. 2014, 28, 485-494.
3. Chen, Q.M.; Bartholomew, J.C.; Campisi, J.; Acosta, M. ; Reagan, J.D.; Ames, B.N. Molecular analysis of H2O2-induced senescent-like growth arrest in normal human fibroblasts: p53 and Rb control G1 arrest but not cell replication. Biochem. J. 1998, 332, 43-50.
4. Zhou, Y.; Dong, Y.; Xu, Q.; He, Y.; Tian, S.; Zhu, S.; Zhu, Y.; Dong, X. Mussel oligopeptides ameliorate cognition deficit and attenuate brain senescence in D-galactose-induced aging mice. Food Chem. Tox icol. 2013, 59, 412-420.
5. Campisi, J.; d? Adda di Fagagna, F. Cellular senescence: When bad things happen to good cells. Nat. Rev. Mol. Cell Bio. 2007, 8, 729-740.
6. Kim, C.O.; Huh, A.J.; Han, S.H.; Kim, J.M. Analysis of cellular senescence induced by lipopolysaccharide in pulmonary alveolar epithelial cells. Arch. Gerontol. Geriatr. 2012, 54, e35-e41.
7. Demidenko, Z.N.; Blagosklonny, M.V. At concentrations that inhibit mTOR, resveratrol suppresses cellular senescence. Cell Cycle. 2009, 8, 1901-1904.
8. Draelos Z.D. Aging skin: The role of diet: Facts and controversies.Clin. Dermatol., 2013, 31, 701-706.
9. Palmer, D.M.; Kitchin, J.S. Oxidative damage, skin aging, antioxidants and a novel antioxidant rating system. J. Drugs Dermatol. 2010, 9, 11-15.
10. Scalzo, J.; Politi, A.; Pellegrini, N.; Mezzetti, B.; Battino, M. Plant genotype affects total antioxidant capacity and phenolic contents in fruit. Nutrition 2005, 21, 207-213.
11. Tulipani, S.; Romandini, S.; Busco, F.; Bompadre, S.; Mezzetti, B.; Battino, M. Ascorbate, not urate, modulates the plasma antioxidant capacity after strawberry intake. Food Chem. 2009, 117, 181-188.
12. Alvarez-Suarez, J.M.; Dekanski, D.; Ristić, S.; Radonjić, N.V.; Petronijević, N.D.; Giampieri, F.; Astolfi, P.; González-Paramás, A. M.; Santos-Buelga, C.; Tulipani, S.; et al. Strawberry polyphenols attenuate ethanol-induced gastric lesions in rats by activation of antioxidant enzymes and attenuation of MDA. PLoS One 2011, 6, e25878.
13. Alvarez-Suarez, J.M.; Giampieri, F.; Tulipani, S.; Casoli, T.; di Stefano, G.; González-Paramá s, A.M.; Santos-Buelga, C.; Busco, F.; Quiles, J.L.; Cordero, M.D.; et al. One-month strawberry-rich an thocyanins supplementation ameliorates cardiovascular risk, oxidative stress markers and platelets activation in humans. J. Nutr. Biochem. 2014, 25, 289-294.
14. Tulipani, S.; Armeni, T.; Giampieri, F.; Alvarez-Suarez, J.M.; Gonzalez-Paramá s, A.M.; Santos-Buelga, C.; Busco, F.; Principato, G.; Bompadre, S.; Quiles, J.L.; et al. Strawberry intake increases blood fluid, erythrocyte and mononuclear cell defenses against oxidat ive challenge. Food Chem. 2014, 156, 87-93.
15. Diamanti, J.; Capocasa, F.; Battino, M.; Mezzetti, B. Evaluation of F. x ananassa intra-specific and inter-specific back-crosses to generate new g enetic material with increased fruit nutritional quality. J. Berry Res. 2010, 1, 103-114.
16. Packer, L. Anti oxidant action of carotenoids in vitro and in vivo protection against oxidation of human low-density lipoproteins. N. Y. Acad. Sci. 1993, 691, 48-60.
17. Solomon, A.; Golubowicz, S.; Yablowiz, Z.; Bergman, M.; Grossman, S.; Altman, A.; Kerem, Z.; Flaishman, M.A. Protection of fibroblasts (NIH-3T3) against oxidative damage by Cyanidin-3-rhamnoglucoside isolated from fig fruits (Ficus carica L.). J. Agric. Food Chem. 2010, 58, 6660-6665.
18. Kaneko, T.; Tahara, S.; Baba, N. Inhibition of linoleic acid hydroperoxide-induced toxicity in cultured human fibroblasts by anthocyanidins. Biosci. Biotechnol. Biochem. 2003, 67, 1391-1393.
19. Giampieri, F.; Tulipani, S.; Alvarez-Suarez, J.M.; Quiles, J.L.; Mezzetti, B.; Battino, M. The strawberry: Composition, nutritional quality, and impact on human health. Nutrition 20 12, 28, 9-19.
20. Tumbas, V.; Canadanovic-Brunet, J.; Gille, L.; Dilas, S.; Cetkovic, G. Superoxide anion radical scavenging activity of bilberry (Vaccinum myrtillus L.). J. Berry Res. 2010, 1, 13-23.
21. Schantz, M.; Mohn, M.; Baum, M.; Richling, E. Antioxdative effic iency of an anthocyanin rich bilberry extract in the human colon tumor cell lines Caco-2 and HT-29. J. Berry Res. 2010, 1, 25-33.
22. Ghosh, D.; McGhie, T.; Zhang, J.; Adaim, A.; Skinner, M. Effects of anthocyanins and other phenolics of boysenberry and blackcurrant as inhibitors of oxidative stress and damage to cellular DNA in SH-SY5Y and HL-60 cells. J. Sci. Food Agric. 2006, 86, 678-686.
23. Esselen, M.; Barth, S.W.; Winkler, S.; Baechler, S.; Briviba, K.; Watzl, B.; Skrbek, S.; Marko, D. Anthocyanins suppress the cleavable complex formation by irinotecan and diminish its DNA-strand-breaking activity in the colon of W istar rats. Carcinogenesis 2013, 34, 835-840.
24. Lopes da Silva, F.; Escribano-Bailon, M.T.; Perez Alonso, J.J.; Rivas-Gonzalo, J.; Santos-Buelga, C. Anthocyanin pigments in strawberry. LWT- Food Scien. Tech. 2007, 40, 374-382.
25. Slinkard, K.; Singleton, V.L. Total phenol analysis: Automation and comparison with manual methods. Am. J. Enol. Vitic. 1977, 28, 49-55.
26. Dewanto, V.; Wu, X.; Adom, K.K.; Liu, R.H. Thermal processing enhances the nutritional values of tomatoes by increasing the total antioxidant activity. J. Agric. Food Chem. 2002, 50, 3010-3014.
27. Helsper, J.P.F.G.; de Vos, C.H.R.; Maas, F.M.; Jonker, H.H.; van den Broeck, H.C.; Jordi, W.; Pot, C.S.; Keizer, L.C.P.; Schapendonk, A.H.C.M. Response of selected antioxidants and pigments in tissues of Rosa hybrida and Fuchsia hybrida to supplemental UV-A exposure. Physiol. Plantarum 2003, 117, 171-187.
28. Zanatta, C.F.; Mercadante, A.Z. Carotenoid composition from the Brazilian tropical fruit camu-camu (Myrciaria dubia). Food Chem. 2007, 101, 1526-1532.
29. Re R.,Pellegrini N.,Proteggente A.,Pannala A.,Yang M.,Rice-Evans C.Antioxidant activity applying an improved ABTS radica l cation decolorization assay.Free Radic. Biol. Med.,1999, 26 1231-1237.
30. Bompadre, S.; Leone, L.; Politi, A.; Battino, M. Improved FIA-ABTS method for antioxidant capacity determination in diffe rent biological samples. Free Radic. Res. 2004, 38, 831-838.
31. Deighton, N.; Brennan, R.; Finn, C.; Davies, H.V. Antioxidant properties of domesticated and wild Rubus species. J. Sci. Food Agric. 2000, 80, 1307-1313.
32. Maines, M.D.; Costa, L.G.; Reed, D.J.; Sassa, S.; Sipes, I.G. Current Protocols in Toxicology; John Wiley & Sons: New York, NY, USA, 1998.
33. . Hempel, S.L.; Buettner, G.R.; O'Malley, Y.Q.; Wessels, D.A.; Flaherty, D.M. Hihydrofluorescein diacetate is superior for detecting intracellular oxidants: Comparison with 2',7'-dichlorodihydrofluorescein diacetate, 5(and 6) -carboxy-2',7'-dichlorodihydrofluorescein diacetate, and dihydrorhodamine 123. Free Radic. Biol. Med. 1999, 27, 146-159.
34. Drummen, G.P.; van Liebergen, L.C.; Op den Kamp, J.A.; Post, J.A. C11-BODIPY (581 /591), an oxidation-sensitive fluorescent lipid peroxidation probe: (micro) spectroscopic characterization and validation of methodology. Free Radic. Biol. Med. 2002, 33, 473-490.
35. Richardson, T.E.; Yu, A.E.; Wen, Y.; Yang, S.H.; Simpkins, J.W. Estrogen prevents oxidative damage to the mitochondria in Friedreich? s ataxia skin fibroblasts. PLoS One 2012, 7, e34600.
36. Singh, N.P.; McCoy, M.T.; Tice, R.R.; Schneider, E.L. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp. Cell Res. 1988, 175, 184-191.
37. Ma chella, N.; Battino, M.; Pisanelli, B.; Regoli, F. Influence of the SCGE protocol on the amount of basal DNA damage detected in the Mediterranean mussel, Mytilus galloprovincialis. Environ. Mol. Mutagen. 2006, 47, 579 -586.