Characterization of grain-specific peptide markers for the detection of gluten by mass spectrometry

Journal of Agricultural and Food Chemistry

Volumn 62, Issue 25, 2014, Pages 5835-5844

  Fiedler, Katherine L ^a   McGrath, Sara C ^a   Callahan, John H ^a   Ross, Mark M ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

celiac disease; gliadin; gluten free; LC MS MS; proteomics; wheat

Indexed keywords

MASS SPECTROMETRY; MOLECULAR BIOLOGY; PEPTIDES; PROTEINS; SPECTROMETRY;

CELIAC DISEASE; GLIADIN; GLUTEN-FREE; LC-MS/MS; PROTEOMICS; WHEAT;

GRAIN (AGRICULTURAL PRODUCT);

AVENA; HORDEUM; SECALE CEREALE; TRITICUM AESTIVUM;

GLUTEN; PEPTIDE;

ANALYSIS; CEREAL; CHEMISTRY; DISCRIMINANT ANALYSIS; EVALUATION STUDY; FOOD CONTAMINATION; PROCEDURES; SPECIES DIFFERENCE; TANDEM MASS SPECTROMETRY; WHEAT;

CEREALS; DISCRIMINANT ANALYSIS; FOOD CONTAMINATION; GLUTENS; PEPTIDES; SPECIES SPECIFICITY; TANDEM MASS SPECTROMETRY; TRITICUM;

EID: 84903289336     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf500997j     Document Type: Article

References (39)

1. Shewry, P. R.; Halford, N. G.; Belton, P. S.; Tatham, A. S. The structure and properties of gluten: an elastic protein from wheat grain Philos. Trans. R Soc. London, B 2002, 357 (1418) 133-142
2. Wieser, H. Chemistry of gluten proteins Food Microbiol. 2007, 24 (2) 115-119
3. Catassi, C.; Fasano, A. Celiac disease Curr. Opin. Gastroenterol. 2008, 24 (6) 687-691
4. Mamone, G.; Picariello, G.; Addeo, F.; Ferranti, P. Proteomic analysis in allergy and intolerance to wheat products Expert Rev. Proteomics 2011, 8 (1) 95-115
5. Ciclitira, P. J.; Ellis, H. J.; Lundin, K. E. A. Gluten-free diet-what is toxic? Best Practice Res. Clin. Gastroenterol. 2005, 19 (3) 359-371
6. Comino, I.; Real, A.; de Lorenzo, L.; Cornell, H.; López-Casado, M. á.; Barro, F.; Lorite, P.; Torres, M. I.; Cebolla, á.; Sousa, C. Diversity in oat potential immunogenicity: basis for the selection of oat varieties with no toxicity in coeliac disease Gut 2011, 60 (7) 915-922
7. Koerner, T.; Cléroux, C.; Poirier, C.; Cantin, I.; Alimkulov, A.; Elamparo, H. Gluten contamination in the Canadian commercial oat supply Food Addit. Contam. 2011, 28 (6) 705-710
8. Hernando, A.; Mujico, J. R.; Mena, M.; Lombardía, M.; Méndez, E. Measurement of wheat gluten and barley hordeins in contaminated oats from Europe, the United States and Canada by sandwich R5 ELISA Eur. J. Gastroenterol. Hepatol. 2008, 20 (6) 545-554
9. Food labeling; gluten-free labeling of foods. Fed. Regist. 2013, 78 (150), 47154-47179.
10. Diaz-Amigo, C.; Popping, B. Accuracy of ELISA detection methods for gluten and reference materials: a realistic assessment J. Agric. Food Chem. 2013, 61 (24) 5681-5688
11. Diaz-Amigo, C.; Popping, B. Gluten and gluten-free: issues and considerations of labeling regulations, detection methods, and assay validation J. AOAC Int. 2012, 95 (2) 337-348
12. Haraszi, R.; Chassaigne, H.; Maquet, A.; Ulberth, F. Analytical methods for detection of gluten in food-method developments in support of food labeling legislation J. AOAC Int. 2011, 94 (4) 1006-1025
13. Sealey-Voyksner, J. A.; Khosla, C.; Voyksner, R. D.; Jorgenson, J. W. Novel aspects of quantitation of immunogenic wheat gluten peptides by liquid chromatography-mass spectrometry/mass spectrometry J. Chromatogr., A 2010, 1217 (25) 4167-4183
14. Shan, L.; Molberg, Ø.; Parrot, I.; Hausch, F.; Filiz, F.; Gray, G. M.; Sollid, L. M.; Khosla, C. Structural basis for gluten intolerance in celiac sprue Science 2002, 297 (5590) 2275-2279
15. Uvackova, L.; Skultety, L.; Bekesova, S.; McClain, S.; Hajduch, M. The MSE-proteomics analysis of gliadins and glutenins in wheat grain identifies and quantifies proteins associated with celiac disease and baker's asthma J. Proteomics 2013, 93, 65-73
16. Altenbach, S. B.; Vensel, W. H.; DuPont, F. M. Integration of transcriptomic and proteomic data from a single wheat cultivar provides new tools for understanding the roles of individual alpha gliadin proteins in flour quality and celiac disease J. Cereal Sci. 2010, 52 (2) 143-151
17. Mamone, G.; Ferranti, P.; Chianese, L.; Scafuri, L.; Addeo, F. Qualitative and quantitative analysis of wheat gluten proteins by liquid chromatography and electrospray mass spectrometry Rapid Commun. Mass Spectrom. 2000, 14 (10) 897-904
18. Méndez, E.; Valdes, I.; Camafeita, E. Analysis of gluten in foods by MALDI-TOFMS. In Mass Spectrometry of Proteins and Peptides; Chapman, J. R., Ed.; Humana Press: Totowa, NJ, USA, 2000; Vol. 146, pp 355-367.
19. Aebersold, R.; Mann, M. Mass spectrometry-based proteomics Nature 2003, 422 (6928) 198-207
20. Vensel, W. H.; Dupont, F. M.; Sloane, S.; Altenbach, S. B. Effect of cleavage enzyme, search algorithm and decoy database on mass spectrometric identification of wheat gluten proteins Phytochemistry 2011, 72 (10) 1154-1161
21. Simonato, B.; Mainente, F.; Tolin, S.; Pasini, G. Immunochemical and mass spectrometry detection of residual proteins in gluten fined red wine J. Agric. Food Chem. 2011, 59 (7) 3101-3110
22. Pompa, M.; Giuliani, M. M.; Palermo, C.; Agriesti, F.; Centonze, D.; Flagella, Z. Comparative analysis of gluten proteins in three durum wheat cultivars by a proteomic approach J. Agric. Food Chem. 2013, 61 (11) 2606-2617
23. Han, B.; Higgs, R. E. Proteomics: from hypothesis to quantitative assay on a single platform. Guidelines for developing MRM assays using ion trap mass spectrometers Brief. Funct. Genomics Proteomics 2008, 7 (5) 340-354
24. Sherrod, S. D.; Myers, M. V.; Li, M.; Myers, J. S.; Carpenter, K. L.; MacLean, B.; MacCoss, M. J.; Liebler, D. C.; Ham, A.-J. L. Label-free quantitation of protein modifications by pseudo selected reaction monitoring with internal reference peptides J. Proteome Res. 2012, 11 (6) 3467-3479
25. Keshishian, H.; Addona, T.; Burgess, M.; Kuhn, E.; Carr, S. A. Quantitative, multiplexed assays for low abundance proteins in plasma by targeted mass spectrometry and stable isotope dilution Mol. Cell. Proteomics 2007, 6 (12) 2212-2229
26. Tatham, A. S.; Gilbert, S. M.; Fido, R. J.; Shewry, P. R. Extraction, separation, and purification of wheat gluten proteins and related proteins of barley, rye, and oats. In Celiac Disease; Springer: Berlin, Germany, 2000; pp 55-73.
27. Wieser, H.; Antes, S.; Seilmeier, W. Quantitative determination of gluten protein types in wheat flour by reversed-phase high-performance liquid chromatography Cereal Chem. 1998, 75 (5) 644-650
28. Rombouts, I.; Lagrain, B.; Brunnbauer, M.; Delcour, J. A.; Koehler, P. Improved identification of wheat gluten proteins through alkylation of cysteine residues and peptide-based mass spectrometry Sci. Rep. 2013, 3 (2279) 1-11
29. Šalplachta, J.; Marchetti, M.; Chmelík, J.; Allmaier, G. A new approach in proteomics of wheat gluten: combining chymotrypsin cleavage and matrix-assisted laser desorption/ionization quadrupole ion trap reflectron tandem mass spectrometry Rapid Commun. Mass Spectrom. 2005, 19 (18) 2725-2728
30. Altenbach, S.; Vensel, W.; DuPont, F. Analysis of expressed sequence tags from a single wheat cultivar facilitates interpretation of tandem mass spectrometry data and discrimination of gamma gliadin proteins that may play different functional roles in flour BMC Plant Biol. 2010, 10 (1) 7
31. Comino, I.; Real, A.; de Lourdes Moreno, M.; Montes, R.; Cebolla, á.; Sousa, C. Immunological determination of gliadin 33-mer equivalent peptides in beers as a specific and practical analytical method to assess safety for celiac patients J. Sci. Food Agric. 2013, 93 (4) 933-943
32. Valdes, I.; Garcia, E.; Llorente, M.; Mendez, E. Innovative approach to low-level gluten determination in foods using a novel sandwich enzyme-linked immunosorbent assay protocol Eur. J. Gastroenterol. Hepatol. 2003, 15 (5) 465-474
33. MacLean, B.; Tomazela, D. M.; Shulman, N.; Chambers, M.; Finney, G. L.; Frewen, B.; Kern, R.; Tabb, D. L.; Liebler, D. C.; MacCoss, M. J. Skyline: an open source document editor for creating and analyzing targeted proteomics experiments Bioinformatics 2010, 26 (7) 966-968
34. Zhang, H.; Liu, Q.; Zimmerman, L. J.; Ham, A.-J. L.; Slebos, R. J. C.; Rahman, J.; Kikuchi, T.; Massion, P. P.; Carbone, D. P.; Billheimer, D.; Liebler, D. C. Methods for peptide and protein quantitation by liquid chromatography-multiple reaction monitoring mass spectrometry. Mol. Cell. Proteomics 2011, DOI: 10.1074/mcp.M110.006593.
35. Anderson, O. D.; Hsia, C. C.; Torres, V. The wheat γ-gliadin genes: characterization of ten new sequences and further understanding of γ-gliadin gene family structure TAG, Theor. Appl. Genetics 2001, 103 (2) 323-330
36. Carr, S. A. Targeted Peptide Measurements in Biology and Medicine: Best Practices for Mass Spectrometry-based Assay Development Using a Fit-for-Purpose Approach Mol. Cell. Proteomics 2014, 7, mcp-M113
37. Guidance for the Analysis and Documentation to Support Regulatory Action On Pesticide Residues; U.S. Food and Drug Administration Office of Regulatory Affairs, Washington, DC, 2009; ORA-Lab.010, (1.4), 1-16.
38. Mass Spectrometry for Confirmation of the Identity of Animal Drug Residues; U.S. Food and Drug Administration Center for Veterinary Medicine, Washington, DC, 2003; Final Guidance for Industry, (118).
39. Peterson, A. C.; Russell, J. D.; Bailey, D. J.; Westphall, M. S.; Coon, J. J. Parallel reaction monitoring for high resolution and high mass accuracy quantitative, targeted proteomics Mol. Cell. Proteomics 2012, 11 (11) 1475-1488