The MSE-proteomic analysis of gliadins and glutenins in wheat grain identifies and quantifies proteins associated with celiac disease and baker's asthma

Journal of Proteomics

Volumn 93, Issue , 2013, Pages 65-73

  Uvackova, Lubica ^a   Skultety, Ludovit ^a,b   Bekesova, Slavka ^b   McClain, Scott ^c   Hajduch, Martin ^a  

^a INSTITUTE OF CHEMISTRY   (Slovakia)

^b INSTITUTE OF VIROLOGY   (Slovakia)

^c SYNGENTA CROP PROTECTION   (United States)

Author keywords

Gliadins; Glutenins; MSE; Proteomics; Quantification; Wheat grain

Indexed keywords

GLIADIN; GLUTENIN;

ARTICLE; ASTHMA; BAKER ASTHMA; CELIAC DISEASE; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEOMICS; VISCOELASTICITY; WHEAT;

TRITICUM AESTIVUM;

COEFFICIENT OF VARIATIONS; CV; DATA-INDEPENDENT MASS SPECTROMETRY; EMPAI; EXPONENTIALLY MODIFIED PROTEIN ABUNDANCE INDEX; GFP; GLIA; GLIADINS; GLU; GLU-1-FIBRINOPEPTIDE B; GLUTENINS; HIGH MOLECULAR WEIGHT GLUTENIN SUBUNITS; HMW GS; LMW GS; LOW MOLECULAR WEIGHT GLUTENIN SUBUNITS; MS(E); MSE; PROTEIN FRACTION CONTAINING MOSTLY GLIADINS; PROTEIN FRACTION CONTAINING MOSTLY GLUTENINS; PROTEOMICS; QUANTIFICATION; WHEAT GRAIN;

ASTHMA; CELIAC DISEASE; GLIADIN; GLUTENS; MASS SPECTROMETRY; PROTEOMICS; TRITICUM;

EID: 84888050445     PISSN: 18743919     EISSN: 18767737     Source Type: Journal    
DOI: 10.1016/j.jprot.2012.12.011     Document Type: Article

References (48)

1. Johansson E., Prieto-Linde M.L., Jönsson J.Ö. Effects of wheat cultivar and nitrogen application on storage protein composition and breadmaking quality. Cereal Chem 2001, 78:19-25.
2. Osborne T.B. The vegetable proteins 1924, Longmans, Green & Co., London.
3. Ferranti P., Mamone G., Picariello G., Addeo F. Mass spectrometry analysis of gliadins in celiac disease. J Mass Spectrom 2007, 42:1531-1548.
4. Payne P.I., Holt L.M., Jarvis M.G., Jackson E.A. Two-dimensional fractionation of the endosperm proteins of bread wheat (Triticum aestivum): biochemical and genetic studies. Cereal Chem 1985, 62:319-326.
5. Jacobsen S., Grove H., Nedenskov Jensen K., Sorensen H.A., Jessen F., Hollung K., et al. Multivariate analysis of 2-DE protein patterns - practical approaches. Electrophoresis 2007, 28:1289-1299.
6. Wieser H. Chemistry of gluten proteins. Food Microbiol 2007, 24:115-119.
7. Wieser H. Relation between gliadin structure and coeliac toxicity. Acta Paediatr 1996, 412(85 Suppl.):3-9.
8. Tatham A.S., Shewry P.R., Belton P.S. Structural studies of cereal prolamins, including wheat gluten. Advances in Cereal Science and Technology 1990, vol. 10. AACC, St Paul. Y. Pomeranz (Ed.).
9. Jackson E.A., Holt L.M., Payne P.I. Characterisation of high molecular-weight gliadin and low-molecular-weight glutenin subunits of wheat endosperm by two-dimensional electrophoresis and the chromosomal localization of their controlling genes. Theor Appl Genet 1983, 66:29.
10. Kan Y., Wan Y., Beaudoin F., Leader D.J., Edwards K., Poole R., et al. Transcriptome analysis reveals differentially expressed storage protein transcripts in seeds of Aegilops and wheat. J Cereal Sci 2006, 44:75-85.
11. Rashtak S., Murray J.A. Review article: coeliac disease, new approaches to therapy. Aliment Pharmacol Ther 2012, 35:768-781.
12. Pietzak M. Celiac disease, wheat allergy, and gluten sensitivity: when gluten free is not a fad. JPEN J Parenter Enteral Nutr 2012, 36(1 Suppl.):68S-75S.
13. Sapone A., Bai J.C., Ciacci C., Dolinsek J., Green P.H., Hadjivassiliou M., et al. Spectrum of gluten-related disorders: consensus on new nomenclature and classification. BMC Med 2012, 10:13.
14. Allred L.K., Ritter B.W. Recognition of gliadin and glutenin fractions in four commercial gluten assays. J AOAC Int 2010, 93:190-196.
15. Sharma G.M. Immunoreactivity and detection of wheat proteins by commercial ELISA kits. J AOAC Int 2012, 95:364-371.
16. Simonato B., Mainente F., Tolin S., Pasini G. Immunochemical and mass spectrometry detection of residual proteins in gluten fined red wine. J Agric Food Chem 2011, 59(7):3101-3110.
17. Silva J.C., Gorenstein M.V., Li G.Z., Vissers J.P.C., Geromanos S.J. Absolute quantification of proteins by LCMSE: a virtue of parallel MS acquisition. Mol Cell Proteomics 2006, 5:144-156.
18. Mbeunkui F., Goshe M.B. Investigation of solubilization and digestion methods for microsomal membrane proteome analysis using data-independent LC-MSE. Proteomics 2011, 11:898-911.
19. Hummel M., Cordewener J.H., de Groot J.C., Smeekens S., America A.H., Hanson J. Dynamic protein composition of Arabidopsis thaliana cytosolic ribosomes in response to sucrose feeding as revealed by label free MSE proteomics. Proteomics 2012, 12:1024-1038.
20. Blackburn K., Cheng F.Y., Williamson J.D., Goshe M.B. Data-independent liquid chromatography/mass spectrometry (LC/MS(E)) detection and quantification of the secreted Apium graveolens pathogen defense protein mannitol dehydrogenase. Rapid Commun Mass Spectrom 2010, 24:1009-1016.
21. Levin Y., Hradetzky E., Bahn S. Quantification of proteins using data-independent analysis (MSE) in simple and complex samples: a systematic evaluation. Proteomics 2011, 11:3273-3287.
22. van den Broeck H.C., America A.H., Smulders M.J., Bosch D., Hamer R.J., Gilissen L.J., et al. A modified extraction protocol enables detection and quantification of celiac disease-related gluten proteins from wheat. J Chromatogr B Analyt Technol Biomed Life Sci 2009, 877:975-982.
23. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976, 72:248-254.
24. Plumb R.S., Johnson K.A., Rainville P., Smith B.W., Wilson I.D., Castro-Perez J.M., et al. UPLC/MS(E); a new approach for generating molecular fragment information for biomarker structure elucidation. Rapid Commun Mass Spectrom 2006, 20:1989-1994.
25. Li G.Z., Vissers J.P., Silva J.C., Golick D., Gorenstein M.V., Geromanos S.J. Database searching and accounting of multiplexed precursor and product ion spectra from the data independent analysis of simple and complex peptide mixtures. Proteomics 2009, 9:1696-1719.
26. Ishihama Y., Oda Y., Tabata T., Sato T., Nagasu T., Rappsilber J., et al. Exponentially modified protein abundance index (em-PAI) for estimation of absolute protein amount in proteomics by the number of sequenced peptides per protein. Mol Cell Proteomics 2005, 4:1265-1272.
27. Pastorello E.A., Farioli L., Conti A., Pravettoni V., Bonomi S., Iametti S., et al. Wheat IgE-mediated food allergy in European patients: α-amylase inhibitors, lipid transfer proteins and low-molecular-weight glutenins. Int Arch Allergy Immunol 2007, 144:10-22.
28. Bevan M., Bancroft I., Bent E., Love K., Goodman H., Dean C., et al. Analysis of 19 Mb of contiguous sequence from chromosome 4 of Arabidopsis thaliana. Nature 1998, 391:485-488.
29. Shewry P.R., Tatham A.S., Lazzeri P. Biotechnology of wheat quality. J Sci Food Agric 1997, 73:397-406.
30. Shan L., Molberg Ø., Parrot I., Hausch F., Filiz F., Gray G.M., et al. Structural basis for gluten intolerance in celiac disease. Science 2002, 297:2275-2279.
31. Battais F., Richard C., Szustakowski G., et al. Wheat flour allergy: an entire diagnostic tool for complex allergy. Allerg Immunol (Paris) 2006, 38:59-61.
32. Palosuo K. Update on wheat hypersensitivity. Curr Opin Allergy Clin Immunol 2003, 3:205-209.
33. Takizawa T., Arakawa H., Tokuyama K., Morikawa A. Identification of allergen fractions of wheat flour responsible for anaphylactic reactions to wheat products in infants and young children. Int Arch Allergy Immunol 2001, 125:51-56.
34. Morita E., Kameyoshi Y., Mihara S., Hiragun T., Yamamoto S. gamma-Gliadin: a presumptive allergen causing wheat-dependent exercise-induced anaphylaxis. Br J Dermatol 2001, 145:182-184.
35. Armentia A., Rodriguez R., Callejo A., et al. Allergy after ingestion or inhalation of cereals involves similar allergens in different ages. Clin Exp Allergy 2002, 32:1216-1222.
36. Shewry P.R., Tatham A.S. The prolamin storage proteins of cereal seeds: structure and evolution. Biochem J 1990, 267:1-12.
37. Gänzle M.G., Loponen J., Gobbetti M. Proteolysis in sourdough fermentations: mechanisms and potential for improved bread quality. Trends Food Sci. Technol. 2008, 19:513-521.
38. Salcedo G., Quirce S., Diaz-Perales A. Wheat allergens associated with baker's asthma. J Investig Allergol Clin Immunol 2011, 21:81-92.
39. Weiss W., Huber G., Engel K.H., Pethran A., Dunn M.J., Gooley A.A., et al. Identification and characterization of wheat grain albumin/globulin allergens. Electrophoresis 1997, 18:826-833.
40. Posch A., Weiss W., Wheeler C., Dunn M.J., Görg A. Sequence analysis of wheat grain allergens separated by two dimensional electrophoresis with immobilized pH gradients. Electrophoresis 1995, 16:1115-1119.
41. Sander I., Flagge A., Merget R., Halder T.M., Meyer H.E., Baur X. Identification of wheat flour allergens by means of 2-dimensional immunoblotting. J Allergy Clin Immunol 2001, 107:907-913.
42. Sandiford C.P., Tee R.D., Newman Taylor A.J. The role of cereal and fungal amylases in cereal flour hypersensitivity. Clin Exp Allergy 1994, 24:549-557.
43. Masci S., D'Ovidio R., Lafiandra D., Kasarda D.D. Characterization of a low-molecular-weight glutenin subunit gene from bread wheat and the corresponding protein that represents a major subunit of the glutenin polymer. Plant Physiol 1998, 118:1147-1158.
44. Kasarda D.D. Glutenin structure in relation to wheat quality. Wheat is unique 1989, 277-302. American Association of Cereal Chemistry, St. Paul, MN.
45. Gu Y.Q., Anderson O.D., Londeorë C.F., Kong X., Chibbar R.N., Lazo G.R. Structural organization of the barley D-hordein locus in comparison with its orthologous regions of wheat genomes. Genome 2003, 46:1084-1097.
46. Jolly C.J., Rahman S., Kortt A.A., Higgins T.J.V. Characterisation of the wheat Mr 15000 "grain-softness protein" and analysis of the relationship between its accumulation in the whole seed and grain softness. Theor Appl Genet 1993, 86:589-597.
47. Morrison W.R., Greenwell P., Law C.N., Sulaiman B.D. Occurrence of friabilin, a low molecular weight protein associated with grain softness, on starch granules isolated from some wheats and related species. J Cereal Sci 1992, 15:143-149.
48. Rahman S., Jolly C.J., Skerritt J.H., Wallosheck A. Cloning of a wheat 15-kDa grain softness protein (GSP). GSP is a mixture of puroindoline-like polypeptides. Eur J Biochem 1994, 223:917-925.