-
1
-
-
0030894162
-
Oxidative stress: oxidants and antioxidants
-
Sies H. Oxidative stress: oxidants and antioxidants. Exp Physiol 1997, 82(2):291-295.
-
(1997)
Exp Physiol
, vol.82
, Issue.2
, pp. 291-295
-
-
Sies, H.1
-
3
-
-
77049308856
-
Aging: a theory based on free radical and radiation chemistry
-
Harman D. Aging: a theory based on free radical and radiation chemistry. J Gerontol 1956, 11(3):298-300.
-
(1956)
J Gerontol
, vol.11
, Issue.3
, pp. 298-300
-
-
Harman, D.1
-
4
-
-
33750347347
-
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
-
Lin M.T., Beal M.F. Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature 2006, 443(7113):787-795.
-
(2006)
Nature
, vol.443
, Issue.7113
, pp. 787-795
-
-
Lin, M.T.1
Beal, M.F.2
-
5
-
-
0037280096
-
SOD2 functions downstream of Sch9 to extend longevity in yeast
-
Fabrizio P., Liou L.L., Moy V.N., et al. SOD2 functions downstream of Sch9 to extend longevity in yeast. Genetics 2003, 163(1):35-46.
-
(2003)
Genetics
, vol.163
, Issue.1
, pp. 35-46
-
-
Fabrizio, P.1
Liou, L.L.2
Moy, V.N.3
-
6
-
-
13944269223
-
The plasticity of aging: insights from long-lived mutants
-
Kenyon C. The plasticity of aging: insights from long-lived mutants. Cell 2005, 120(4):449-460.
-
(2005)
Cell
, vol.120
, Issue.4
, pp. 449-460
-
-
Kenyon, C.1
-
7
-
-
0033581704
-
The p66shc adaptor protein controls oxidative stress response and life span in mammals
-
Migliaccio E., Giorgio M., Mele S., et al. The p66shc adaptor protein controls oxidative stress response and life span in mammals. Nature 1999, 402(6759):309-313.
-
(1999)
Nature
, vol.402
, Issue.6759
, pp. 309-313
-
-
Migliaccio, E.1
Giorgio, M.2
Mele, S.3
-
8
-
-
0026795635
-
Protein oxidation and aging
-
Stadtman E.R. Protein oxidation and aging. Science 1992, 257(5074):1220-1224.
-
(1992)
Science
, vol.257
, Issue.5074
, pp. 1220-1224
-
-
Stadtman, E.R.1
-
9
-
-
63149135685
-
The Mn-superoxide dismutase single nucleotide polymorphism rs4880 and the glutathione peroxidase 1 single nucleotide polymorphism rs1050450 are associated with aging and longevity in the oldest old
-
Soerensen M., Christensen K., Stevnsner T., Christiansen L. The Mn-superoxide dismutase single nucleotide polymorphism rs4880 and the glutathione peroxidase 1 single nucleotide polymorphism rs1050450 are associated with aging and longevity in the oldest old. Mech Ageing Dev 2009, 130(5):308-314.
-
(2009)
Mech Ageing Dev
, vol.130
, Issue.5
, pp. 308-314
-
-
Soerensen, M.1
Christensen, K.2
Stevnsner, T.3
Christiansen, L.4
-
10
-
-
75149114104
-
Association between SOD2 T-9C and MTHFR C677T polymorphisms and longevity: a study in a Jordanian population
-
Khabour O.F., Abdelhalim E.S., Abu-Wardeh A. Association between SOD2 T-9C and MTHFR C677T polymorphisms and longevity: a study in a Jordanian population. BMC Geriatr 2009, 9:57.
-
(2009)
BMC Geriatr
, vol.9
, pp. 57
-
-
Khabour, O.F.1
Abdelhalim, E.S.2
Abu-Wardeh, A.3
-
11
-
-
33744913541
-
Research agenda for frailty in older adults: toward a better understanding of physiology and etiology: summary from the American Geriatrics Society/National Institute on Aging Research Conference on Frailty in Older Adults
-
Walston J., Hadley E.C., Ferrucci L., et al. Research agenda for frailty in older adults: toward a better understanding of physiology and etiology: summary from the American Geriatrics Society/National Institute on Aging Research Conference on Frailty in Older Adults. J Am Geriatr Soc 2006, 54(6):991-1001.
-
(2006)
J Am Geriatr Soc
, vol.54
, Issue.6
, pp. 991-1001
-
-
Walston, J.1
Hadley, E.C.2
Ferrucci, L.3
-
13
-
-
34247129982
-
Insulin resistance and inflammation as precursors of frailty: the Cardiovascular Health Study
-
Barzilay J.I., Blaum C., Moore T., et al. Insulin resistance and inflammation as precursors of frailty: the Cardiovascular Health Study. Arch Intern Med 2007, 167(7):635-641.
-
(2007)
Arch Intern Med
, vol.167
, Issue.7
, pp. 635-641
-
-
Barzilay, J.I.1
Blaum, C.2
Moore, T.3
-
14
-
-
0001296914
-
Accumulation of deficits as a proxy measure of aging
-
Mitnitski A.B., Mogilner A.J., Rockwood K. Accumulation of deficits as a proxy measure of aging. Sci World J 2001, 1:323-336.
-
(2001)
Sci World J
, vol.1
, pp. 323-336
-
-
Mitnitski, A.B.1
Mogilner, A.J.2
Rockwood, K.3
-
15
-
-
29344473757
-
Relative fitness and frailty of elderly men and women in developed countries and their relationship with mortality
-
Mitnitski A., Song X., Skoog I., et al. Relative fitness and frailty of elderly men and women in developed countries and their relationship with mortality. J Am Geriatr Soc 2005, 53(12):2184-2189.
-
(2005)
J Am Geriatr Soc
, vol.53
, Issue.12
, pp. 2184-2189
-
-
Mitnitski, A.1
Song, X.2
Skoog, I.3
-
16
-
-
0032564824
-
Risk factors for 5-year mortality in older adults: the Cardiovascular Health Study
-
Fried L.P., Kronmal R.A., Newman A.B., et al. Risk factors for 5-year mortality in older adults: the Cardiovascular Health Study. JAMA 1998, 279(8):585-592.
-
(1998)
JAMA
, vol.279
, Issue.8
, pp. 585-592
-
-
Fried, L.P.1
Kronmal, R.A.2
Newman, A.B.3
-
17
-
-
50049120029
-
Sarcopenia: diagnosis and treatment
-
Morley J.E. Sarcopenia: diagnosis and treatment. J Nutr Health Aging 2008, 12(7):452-456.
-
(2008)
J Nutr Health Aging
, vol.12
, Issue.7
, pp. 452-456
-
-
Morley, J.E.1
-
18
-
-
34247568590
-
Alternative definitions of sarcopenia, lower extremity performance, and functional impairment with aging in older men and women
-
Delmonico M.J., Harris T.B., Lee J.S., et al. Alternative definitions of sarcopenia, lower extremity performance, and functional impairment with aging in older men and women. J Am Geriatr Soc 2007, 55(5):769-774.
-
(2007)
J Am Geriatr Soc
, vol.55
, Issue.5
, pp. 769-774
-
-
Delmonico, M.J.1
Harris, T.B.2
Lee, J.S.3
-
19
-
-
0034996580
-
Attenuation of skeletal muscle and strength in the elderly: the Health ABC Study
-
Goodpaster B.H., Carlson C.L., Visser M., et al. Attenuation of skeletal muscle and strength in the elderly: the Health ABC Study. J Appl Physiol 2001, 90(6):2157-2165.
-
(2001)
J Appl Physiol
, vol.90
, Issue.6
, pp. 2157-2165
-
-
Goodpaster, B.H.1
Carlson, C.L.2
Visser, M.3
-
20
-
-
0036073319
-
Longitudinal changes in body composition in older men and women: role of body weight change and physical activity
-
Hughes V.A., Frontera W.R., Roubenoff R., et al. Longitudinal changes in body composition in older men and women: role of body weight change and physical activity. Am J Clin Nutr 2002, 76(2):473-481.
-
(2002)
Am J Clin Nutr
, vol.76
, Issue.2
, pp. 473-481
-
-
Hughes, V.A.1
Frontera, W.R.2
Roubenoff, R.3
-
21
-
-
77950509657
-
Frailty, body mass index, and abdominal obesity in older people
-
Hubbard R.E., Lang I.A., Llewellyn D.J., Rockwood K. Frailty, body mass index, and abdominal obesity in older people. J Gerontol A Biol Sci Med Sci 2010, 65(4):377-381.
-
(2010)
J Gerontol A Biol Sci Med Sci
, vol.65
, Issue.4
, pp. 377-381
-
-
Hubbard, R.E.1
Lang, I.A.2
Llewellyn, D.J.3
Rockwood, K.4
-
22
-
-
79151484704
-
Adipokines in inflammation and metabolic disease
-
Ouchi N., Parker J.L., Lugus J.J., Walsh K. Adipokines in inflammation and metabolic disease. Nat Rev Immunol 2011, 11(2):85-97.
-
(2011)
Nat Rev Immunol
, vol.11
, Issue.2
, pp. 85-97
-
-
Ouchi, N.1
Parker, J.L.2
Lugus, J.J.3
Walsh, K.4
-
23
-
-
15244348518
-
The origins of age-related proinflammatory state
-
Ferrucci L., Corsi A., Lauretani F., et al. The origins of age-related proinflammatory state. Blood 2005, 105(6):2294-2299.
-
(2005)
Blood
, vol.105
, Issue.6
, pp. 2294-2299
-
-
Ferrucci, L.1
Corsi, A.2
Lauretani, F.3
-
24
-
-
33750595325
-
Targeted ablation of IKK2 improves skeletal muscle strength, maintains mass, and promotes regeneration
-
Mourkioti F., Kratsios P., Luedde T., et al. Targeted ablation of IKK2 improves skeletal muscle strength, maintains mass, and promotes regeneration. J Clin Invest 2006, 116(11):2945-2954.
-
(2006)
J Clin Invest
, vol.116
, Issue.11
, pp. 2945-2954
-
-
Mourkioti, F.1
Kratsios, P.2
Luedde, T.3
-
25
-
-
0036903170
-
Change in muscle strength explains accelerated decline of physical function in older women with high interleukin-6 serum levels
-
Ferrucci L., Penninx B.W., Volpato S., et al. Change in muscle strength explains accelerated decline of physical function in older women with high interleukin-6 serum levels. J Am Geriatr Soc 2002, 50(12):1947-1954.
-
(2002)
J Am Geriatr Soc
, vol.50
, Issue.12
, pp. 1947-1954
-
-
Ferrucci, L.1
Penninx, B.W.2
Volpato, S.3
-
26
-
-
0035127960
-
Resistance exercise decreases skeletal muscle tumor necrosis factor alpha in frail elderly humans
-
Greiwe J.S., Cheng B., Rubin D.C., et al. Resistance exercise decreases skeletal muscle tumor necrosis factor alpha in frail elderly humans. FASEB J 2001, 15(2):475-482.
-
(2001)
FASEB J
, vol.15
, Issue.2
, pp. 475-482
-
-
Greiwe, J.S.1
Cheng, B.2
Rubin, D.C.3
-
27
-
-
0036170745
-
Age trends in the level of serum testosterone and other hormones in middle-aged men: longitudinal results from the Massachusetts male aging study
-
Feldman H.A., Longcope C., Derby C.A., et al. Age trends in the level of serum testosterone and other hormones in middle-aged men: longitudinal results from the Massachusetts male aging study. J Clin Endocrinol Metab 2002, 87(2):589-598.
-
(2002)
J Clin Endocrinol Metab
, vol.87
, Issue.2
, pp. 589-598
-
-
Feldman, H.A.1
Longcope, C.2
Derby, C.A.3
-
28
-
-
58149494750
-
Testicular disorders
-
Saudners, Philadelphia, H.M. Kronenberg, S. Melmed, K.S. Polonsky, P.R. Larsen (Eds.) 11th ed.
-
Bhasin S. Testicular disorders. Williams textbook of endocrinology 2008, 645-699. Saudners, Philadelphia. 11th ed. H.M. Kronenberg, S. Melmed, K.S. Polonsky, P.R. Larsen (Eds.).
-
(2008)
Williams textbook of endocrinology
, pp. 645-699
-
-
Bhasin, S.1
-
29
-
-
78649527705
-
Low serum testosterone and frailty in older men and women
-
Wu I.C., Lin X.Z., Liu P.F., et al. Low serum testosterone and frailty in older men and women. Maturitas 2010, 67(4):348-352.
-
(2010)
Maturitas
, vol.67
, Issue.4
, pp. 348-352
-
-
Wu, I.C.1
Lin, X.Z.2
Liu, P.F.3
-
31
-
-
0034853487
-
Association of IGF-I levels with muscle strength and mobility in older women
-
Cappola A.R., Bandeen-Roche K., Wand G.S., et al. Association of IGF-I levels with muscle strength and mobility in older women. J Clin Endocrinol Metab 2001, 86(9):4139-4146.
-
(2001)
J Clin Endocrinol Metab
, vol.86
, Issue.9
, pp. 4139-4146
-
-
Cappola, A.R.1
Bandeen-Roche, K.2
Wand, G.S.3
-
32
-
-
0029011908
-
The age of dehydroepiandrosterone
-
Herbert J. The age of dehydroepiandrosterone. Lancet 1995, 345(8959):1193-1194.
-
(1995)
Lancet
, vol.345
, Issue.8959
, pp. 1193-1194
-
-
Herbert, J.1
-
33
-
-
67649436019
-
The association between dehydroepiandosterone and frailty in older men and women
-
Voznesensky M., Walsh S., Dauser D., et al. The association between dehydroepiandosterone and frailty in older men and women. Age Ageing 2009, 38(4):401-406.
-
(2009)
Age Ageing
, vol.38
, Issue.4
, pp. 401-406
-
-
Voznesensky, M.1
Walsh, S.2
Dauser, D.3
-
34
-
-
0034325276
-
Human ageing and the sympathoadrenal system
-
Seals D.R., Esler M.D. Human ageing and the sympathoadrenal system. J Physiol 2000, 528(Pt 3):407-417.
-
(2000)
J Physiol
, vol.528
, Issue.PT 3
, pp. 407-417
-
-
Seals, D.R.1
Esler, M.D.2
-
35
-
-
66149096596
-
Frailty and impaired cardiac autonomic control: new insights from principal components aggregation of traditional heart rate variability indices
-
Varadhan R., Chaves P.H., Lipsitz L.A., et al. Frailty and impaired cardiac autonomic control: new insights from principal components aggregation of traditional heart rate variability indices. J Gerontol A Biol Sci Med Sci 2009, 64(6):682-687.
-
(2009)
J Gerontol A Biol Sci Med Sci
, vol.64
, Issue.6
, pp. 682-687
-
-
Varadhan, R.1
Chaves, P.H.2
Lipsitz, L.A.3
-
36
-
-
34447651103
-
Oxidative protein damage is associated with poor grip strength among older women living in the community
-
Howard C., Ferrucci L., Sun K., et al. Oxidative protein damage is associated with poor grip strength among older women living in the community. J Appl Physiol 2007, 103(1):17-20.
-
(2007)
J Appl Physiol
, vol.103
, Issue.1
, pp. 17-20
-
-
Howard, C.1
Ferrucci, L.2
Sun, K.3
-
37
-
-
36549062132
-
Oxidative stress and severe walking disability among older women
-
Semba R.D., Ferrucci L., Sun K., et al. Oxidative stress and severe walking disability among older women. Am J Med 2007, 120(12):1084-1089.
-
(2007)
Am J Med
, vol.120
, Issue.12
, pp. 1084-1089
-
-
Semba, R.D.1
Ferrucci, L.2
Sun, K.3
-
38
-
-
0041922325
-
The isoprostanes: unique products of arachidonic acid oxidation-a review
-
Fam S.S., Morrow J.D. The isoprostanes: unique products of arachidonic acid oxidation-a review. Curr Med Chem 2003, 10(17):1723-1740.
-
(2003)
Curr Med Chem
, vol.10
, Issue.17
, pp. 1723-1740
-
-
Fam, S.S.1
Morrow, J.D.2
-
39
-
-
84861025869
-
Oxidative damage, platelet activation, and inflammation to predict mobility disability and mortality in older persons: results from the health, aging, and body composition study
-
Cesari M., Kritchevsky S.B., Nicklas B., et al. Oxidative damage, platelet activation, and inflammation to predict mobility disability and mortality in older persons: results from the health, aging, and body composition study. J Gerontol A Biol Sci Med Sci 2012, 67(6):671-676.
-
(2012)
J Gerontol A Biol Sci Med Sci
, vol.67
, Issue.6
, pp. 671-676
-
-
Cesari, M.1
Kritchevsky, S.B.2
Nicklas, B.3
-
40
-
-
26444574826
-
Lipoprotein peroxidation and mobility limitation: results from the Health, Aging, and Body Composition Study
-
Cesari M., Kritchevsky S.B., Nicklas B.J., et al. Lipoprotein peroxidation and mobility limitation: results from the Health, Aging, and Body Composition Study. Arch Intern Med 2005, 165(18):2148-2154.
-
(2005)
Arch Intern Med
, vol.165
, Issue.18
, pp. 2148-2154
-
-
Cesari, M.1
Kritchevsky, S.B.2
Nicklas, B.J.3
-
41
-
-
70350560239
-
Frailty syndrome is associated with altered circulating redox balance and increased markers of oxidative stress
-
Serviddio G., Romano A.D., Greco A., et al. Frailty syndrome is associated with altered circulating redox balance and increased markers of oxidative stress. Int J Immunopathol Pharmacol 2009, 22(3):819-827.
-
(2009)
Int J Immunopathol Pharmacol
, vol.22
, Issue.3
, pp. 819-827
-
-
Serviddio, G.1
Romano, A.D.2
Greco, A.3
-
42
-
-
0038799736
-
Oxidative DNA damage: mechanisms, mutation, and disease
-
Cooke M.S., Evans M.D., Dizdaroglu M., Lunec J. Oxidative DNA damage: mechanisms, mutation, and disease. FASEB J 2003, 17(10):1195-1214.
-
(2003)
FASEB J
, vol.17
, Issue.10
, pp. 1195-1214
-
-
Cooke, M.S.1
Evans, M.D.2
Dizdaroglu, M.3
Lunec, J.4
-
43
-
-
69549124156
-
High oxidative stress is correlated with frailty in elderly Chinese
-
Wu I.C., Shiesh S.C., Kuo P.H., Lin X.Z. High oxidative stress is correlated with frailty in elderly Chinese. J Am American Geriatr Soc 2009, 57(9):1666-1671.
-
(2009)
J Am American Geriatr Soc
, vol.57
, Issue.9
, pp. 1666-1671
-
-
Wu, I.C.1
Shiesh, S.C.2
Kuo, P.H.3
Lin, X.Z.4
-
44
-
-
2442619131
-
Detection of reactive oxygen and nitrogen species by EPR spin trapping
-
Villamena F.A., Zweier J.L. Detection of reactive oxygen and nitrogen species by EPR spin trapping. Antioxid Redox Signal 2004, 6(3):619-629.
-
(2004)
Antioxid Redox Signal
, vol.6
, Issue.3
, pp. 619-629
-
-
Villamena, F.A.1
Zweier, J.L.2
-
45
-
-
84864655470
-
Low-grade chronic inflammation and superoxide anion production by NADPH oxidase are the main determinants of physical frailty in older adults
-
Baptista G., Dupuy A.M., Jaussent A., et al. Low-grade chronic inflammation and superoxide anion production by NADPH oxidase are the main determinants of physical frailty in older adults. Free Radic Res 2012, 46(9):1108-1114.
-
(2012)
Free Radic Res
, vol.46
, Issue.9
, pp. 1108-1114
-
-
Baptista, G.1
Dupuy, A.M.2
Jaussent, A.3
-
46
-
-
0028827252
-
Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase
-
Li Y., Huang T.T., Carlson E.J., et al. Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase. Nat Genet 1995, 11(4):376-381.
-
(1995)
Nat Genet
, vol.11
, Issue.4
, pp. 376-381
-
-
Li, Y.1
Huang, T.T.2
Carlson, E.J.3
-
47
-
-
0032561328
-
Increased oxidative damage is correlated to altered mitochondrial function in heterozygous manganese superoxide dismutase knockout mice
-
Williams M.D., Van Remmen H., Conrad C.C., et al. Increased oxidative damage is correlated to altered mitochondrial function in heterozygous manganese superoxide dismutase knockout mice. J Biol Chem 1998, 273(43):28510-28515.
-
(1998)
J Biol Chem
, vol.273
, Issue.43
, pp. 28510-28515
-
-
Williams, M.D.1
Van Remmen, H.2
Conrad, C.C.3
-
48
-
-
1642377274
-
Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes
-
Petersen K.F., Dufour S., Befroy D., et al. Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes. N Engl J Med 2004, 350(7):664-671.
-
(2004)
N Engl J Med
, vol.350
, Issue.7
, pp. 664-671
-
-
Petersen, K.F.1
Dufour, S.2
Befroy, D.3
-
49
-
-
2642580016
-
Premature ageing in mice expressing defective mitochondrial DNA polymerase
-
Trifunovic A., Wredenberg A., Falkenberg M., et al. Premature ageing in mice expressing defective mitochondrial DNA polymerase. Nature 2004, 429(6990):417-423.
-
(2004)
Nature
, vol.429
, Issue.6990
, pp. 417-423
-
-
Trifunovic, A.1
Wredenberg, A.2
Falkenberg, M.3
-
50
-
-
0344927165
-
Regulation of ion channel structure and function by reactive oxygen-nitrogen species
-
Matalon S., Hardiman K.M., Jain L., et al. Regulation of ion channel structure and function by reactive oxygen-nitrogen species. Am J Physiol Lung Cell Mol Physiol 2003, 285(6):L1184-1189.
-
(2003)
Am J Physiol Lung Cell Mol Physiol
, vol.285
, Issue.6
-
-
Matalon, S.1
Hardiman, K.M.2
Jain, L.3
-
51
-
-
85047693596
-
Activation of caspase-3 is an initial step triggering accelerated muscle proteolysis in catabolic conditions
-
Du J., Wang X., Miereles C., et al. Activation of caspase-3 is an initial step triggering accelerated muscle proteolysis in catabolic conditions. J Clin Invest 2004, 113(1):115-123.
-
(2004)
J Clin Invest
, vol.113
, Issue.1
, pp. 115-123
-
-
Du, J.1
Wang, X.2
Miereles, C.3
-
52
-
-
0035425503
-
Nitric oxide synthases: structure, function and inhibition
-
Alderton W.K., Cooper C.E., Knowles R.G. Nitric oxide synthases: structure, function and inhibition. Biochem J 2001, 357(Pt 3):593-615.
-
(2001)
Biochem J
, vol.357
, Issue.PT 3
, pp. 593-615
-
-
Alderton, W.K.1
Cooper, C.E.2
Knowles, R.G.3
-
53
-
-
0036260697
-
Cellular response to oxidative stress: signaling for suicide and survival
-
Martindale J.L., Holbrook N.J. Cellular response to oxidative stress: signaling for suicide and survival. J Cell Physiol 2002, 192(1):1-15.
-
(2002)
J Cell Physiol
, vol.192
, Issue.1
, pp. 1-15
-
-
Martindale, J.L.1
Holbrook, N.J.2
-
54
-
-
0029838063
-
Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice
-
Lebovitz R.M., Zhang H., Vogel H., et al. Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice. Proc Natl Acad Sci USA 1996, 93(18):9782-9787.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, Issue.18
, pp. 9782-9787
-
-
Lebovitz, R.M.1
Zhang, H.2
Vogel, H.3
-
55
-
-
33646588683
-
Absence of CuZn superoxide dismutase leads to elevated oxidative stress and acceleration of age-dependent skeletal muscle atrophy
-
Muller F.L., Song W., Liu Y., et al. Absence of CuZn superoxide dismutase leads to elevated oxidative stress and acceleration of age-dependent skeletal muscle atrophy. Free Radic Biol Med 2006, 40(11):1993-2004.
-
(2006)
Free Radic Biol Med
, vol.40
, Issue.11
, pp. 1993-2004
-
-
Muller, F.L.1
Song, W.2
Liu, Y.3
-
56
-
-
34548186667
-
Cellular senescence: when bad things happen to good cells
-
Campisi J., d'Adda di Fagagna F. Cellular senescence: when bad things happen to good cells. Nat Rev Mol Cell Biol 2007, 8(9):729-740.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, Issue.9
, pp. 729-740
-
-
Campisi, J.1
d'Adda di Fagagna, F.2
-
57
-
-
33749187810
-
P16INK4a induces an age-dependent decline in islet regenerative potential
-
Krishnamurthy J., Ramsey M.R., Ligon K.L., et al. p16INK4a induces an age-dependent decline in islet regenerative potential. Nature 2006, 443(7110):453-457.
-
(2006)
Nature
, vol.443
, Issue.7110
, pp. 453-457
-
-
Krishnamurthy, J.1
Ramsey, M.R.2
Ligon, K.L.3
-
58
-
-
33749171885
-
Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing
-
Molofsky A.V., Slutsky S.G., Joseph N.M., et al. Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing. Nature 2006, 443(7110):448-452.
-
(2006)
Nature
, vol.443
, Issue.7110
, pp. 448-452
-
-
Molofsky, A.V.1
Slutsky, S.G.2
Joseph, N.M.3
-
59
-
-
69949150673
-
A crucial role for adipose tissue p53 in the regulation of insulin resistance
-
Minamino T., Orimo M., Shimizu I., et al. A crucial role for adipose tissue p53 in the regulation of insulin resistance. Nat Med 2009, 15(9):1082-1087.
-
(2009)
Nat Med
, vol.15
, Issue.9
, pp. 1082-1087
-
-
Minamino, T.1
Orimo, M.2
Shimizu, I.3
-
60
-
-
0037011958
-
P53 mutant mice that display early ageing-associated phenotypes
-
Tyner S.D., Venkatachalam S., Choi J., et al. p53 mutant mice that display early ageing-associated phenotypes. Nature 2002, 415(6867):45-53.
-
(2002)
Nature
, vol.415
, Issue.6867
, pp. 45-53
-
-
Tyner, S.D.1
Venkatachalam, S.2
Choi, J.3
-
61
-
-
15844409553
-
Positional cloning of the Werner's syndrome gene
-
Yu C.E., Oshima J., Fu Y.H., et al. Positional cloning of the Werner's syndrome gene. Science 1996, 272(5259):258-262.
-
(1996)
Science
, vol.272
, Issue.5259
, pp. 258-262
-
-
Yu, C.E.1
Oshima, J.2
Fu, Y.H.3
-
62
-
-
3543043128
-
Essential role of limiting telomeres in the pathogenesis of Werner syndrome
-
Chang S., Multani A.S., Cabrera N.G., et al. Essential role of limiting telomeres in the pathogenesis of Werner syndrome. Nat Genet 2004, 36(8):877-882.
-
(2004)
Nat Genet
, vol.36
, Issue.8
, pp. 877-882
-
-
Chang, S.1
Multani, A.S.2
Cabrera, N.G.3
-
63
-
-
17544402913
-
Mutations in the WRN gene in mice accelerate mortality in a p53-null background
-
Lombard D.B., Beard C., Johnson B., et al. Mutations in the WRN gene in mice accelerate mortality in a p53-null background. Mol Cell Biol 2000, 20(9):3286-3291.
-
(2000)
Mol Cell Biol
, vol.20
, Issue.9
, pp. 3286-3291
-
-
Lombard, D.B.1
Beard, C.2
Johnson, B.3
-
64
-
-
80855138775
-
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
-
Baker D.J., Wijshake T., Tchkonia T., et al. Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders. Nature 2011, 479(7372):232-236.
-
(2011)
Nature
, vol.479
, Issue.7372
, pp. 232-236
-
-
Baker, D.J.1
Wijshake, T.2
Tchkonia, T.3
-
65
-
-
3042761646
-
BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice
-
Baker D.J., Jeganathan K.B., Cameron J.D., et al. BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice. Nat Genet 2004, 36(7):744-749.
-
(2004)
Nat Genet
, vol.36
, Issue.7
, pp. 744-749
-
-
Baker, D.J.1
Jeganathan, K.B.2
Cameron, J.D.3
-
66
-
-
34648813720
-
ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis
-
D'Autreaux B., Toledano M.B. ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis. Nat Rev Mol Cell Biol 2007, 8(10):813-824.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, Issue.10
, pp. 813-824
-
-
D'Autreaux, B.1
Toledano, M.B.2
-
67
-
-
7044230885
-
Possible novel therapy for diabetes with cell-permeable JNK-inhibitory peptide
-
Kaneto H., Nakatani Y., Miyatsuka T., et al. Possible novel therapy for diabetes with cell-permeable JNK-inhibitory peptide. Nat Med 2004, 10(10):1128-1132.
-
(2004)
Nat Med
, vol.10
, Issue.10
, pp. 1128-1132
-
-
Kaneto, H.1
Nakatani, Y.2
Miyatsuka, T.3
-
68
-
-
0034733807
-
Redox-dependent signal transduction
-
Finkel T. Redox-dependent signal transduction. FEBS Lett 2000, 476(1-2):52-54.
-
(2000)
FEBS Lett
, vol.476
, Issue.1-2
, pp. 52-54
-
-
Finkel, T.1
-
69
-
-
0036802207
-
Pharmaco-redox regulation of cytokine-related pathways: from receptor signaling to pharmacogenomics
-
Haddad J.J. Pharmaco-redox regulation of cytokine-related pathways: from receptor signaling to pharmacogenomics. Free Radic Biol Med 2002, 33(7):907-926.
-
(2002)
Free Radic Biol Med
, vol.33
, Issue.7
, pp. 907-926
-
-
Haddad, J.J.1
|