메뉴 건너뛰기




Volumn 54, Issue 6, 2006, Pages 991-1001

Research agenda for frailty in older adults: Toward a better understanding of physiology and etiology: Summary from the American Geriatrics Society/National Institute on Aging research conference on frailty in older adults

Author keywords

Frailty; Multisystem decline; Pathophysiology

Indexed keywords

AGED; AGING; CONFERENCE PAPER; ELDERLY CARE; FRAIL ELDERLY; HEALTH CARE SYSTEM; HUMAN; MEDICAL RESEARCH; MEDICAL SOCIETY; NONHUMAN; PHENOTYPE;

EID: 33744913541     PISSN: 00028614     EISSN: 15325415     Source Type: Journal    
DOI: 10.1111/j.1532-5415.2006.00745.x     Document Type: Conference Paper
Times cited : (1237)

References (52)
  • 2
    • 0344761961 scopus 로고    scopus 로고
    • How to select a frail elderly population? a comparison of three working definitions
    • Chin A Paw MJ Dekker JM et al. How to select a frail elderly population? A comparison of three working definitions. J Clin Epidemiol 1999 52 : 1015 1021.
    • (1999) J Clin Epidemiol , vol.52 , pp. 1015-1021
    • Chin, A.1    Paw, M.J.2    Dekker, J.M.3
  • 3
    • 1842784019 scopus 로고    scopus 로고
    • Designing randomized, controlled trials aimed at preventing or delaying functional decline and disability in frail, older persons: A consensus report
    • Ferrucci L Guralnik JM Studenski S et al. Designing randomized, controlled trials aimed at preventing or delaying functional decline and disability in frail, older persons: A consensus report. J Am Geriatr Soc 2004 52 : 625 634.
    • (2004) J Am Geriatr Soc , vol.52 , pp. 625-634
    • Ferrucci, L.1    Guralnik, J.M.2    Studenski, S.3
  • 4
    • 4444352300 scopus 로고    scopus 로고
    • Clinical global impression of change in physical frailty: Development of a measure based on clinical judgment
    • Studenski S Hayes RP Leibowitz RQ et al. Clinical global impression of change in physical frailty: Development of a measure based on clinical judgment. J Am Geriatr Soc 2004 52 : 1560 1566.
    • (2004) J Am Geriatr Soc , vol.52 , pp. 1560-1566
    • Studenski, S.1    Hayes, R.P.2    Leibowitz, R.Q.3
  • 5
    • 0002509156 scopus 로고    scopus 로고
    • Frailty and failure to thrive
    • In: Hazzard, W. Blass, J.P. Halter, J.B.*et al., eds. New York: McGraw-Hill, pp
    • Fried LP Walston J. Frailty and failure to thrive. In : Hazzard W Blass JP Halter JB et al., eds. Principles of Geriatric Medicine and Gerontology, 5th Ed. New York : McGraw-Hill, 2003, pp 1487 1502.
    • (2003) Principles of Geriatric Medicine and Gerontology, 5th Ed. , pp. 1487-1502
    • Fried, L.P.1    Walston, J.2
  • 6
    • 2642511870 scopus 로고    scopus 로고
    • Frailty and its implications for care
    • In: Morrison, R.S. Meir, D.E., eds. New York: Oxford University Press, pp
    • Walston JD Fried LP. Frailty and its implications for care. In : Morrison RS Meir DE, eds. Geriatric Palliative Care. New York : Oxford University Press, 2003, pp 93 109.
    • (2003) Geriatric Palliative Care. , pp. 93-109
    • Walston, J.D.1    Fried, L.P.2
  • 7
    • 23444440343 scopus 로고    scopus 로고
    • Frailty and its definition: A worthy challenge
    • Rockwood K. Frailty and its definition: A worthy challenge. J Am Geriatr Soc 2005 53 : 1069 1070.
    • (2005) J Am Geriatr Soc , vol.53 , pp. 1069-1070
    • Rockwood, K.1
  • 8
    • 0026806138 scopus 로고
    • Conference on the physiologic basis of frailty, April 28, 1992, Baltimore, Maryland, U.S.A. Introduction
    • Fried LP. Conference on the physiologic basis of frailty, April 28, 1992, Baltimore, Maryland, U.S.A. Introduction. Aging (Milano) 1992 4 : 251 252.
    • (1992) Aging (Milano) , vol.4 , pp. 251-252
    • Fried, L.P.1
  • 10
    • 0037111615 scopus 로고    scopus 로고
    • Frailty and activation of the inflammation and coagulation systems with and without clinical morbidities: Results from the Cardiovascular Health Study
    • Walston J McBurnie MA Newman A et al. Frailty and activation of the inflammation and coagulation systems with and without clinical morbidities: Results from the Cardiovascular Health Study. Arch Intern Med 2002 162 : 2333 2341.
    • (2002) Arch Intern Med , vol.162 , pp. 2333-2341
    • Walston, J.1    McBurnie, M.A.2    Newman, A.3
  • 11
    • 0026534404 scopus 로고
    • Loss of 'complexity' and aging. Potential applications of fractals and chaos theory to senescence
    • Lipsitz LA Goldberger AL. Loss of 'complexity' and aging. Potential applications of fractals and chaos theory to senescence. JAMA 1992 267 : 1806 1809.
    • (1992) JAMA , vol.267 , pp. 1806-1809
    • Lipsitz, L.A.1    Goldberger, A.L.2
  • 12
    • 0036197712 scopus 로고    scopus 로고
    • Dynamics of stability. the physiologic basis of functional health and frailty
    • Lipsitz LA. Dynamics of stability. The physiologic basis of functional health and frailty. J Gerontol A Biol Sci Med Sci 2002 57A : B115 B125.
    • (2002) J Gerontol a Biol Sci Med Sci , vol.57
    • Lipsitz, L.A.1
  • 13
    • 0038626827 scopus 로고    scopus 로고
    • Interleukin balance and early recovery from anesthesia in elderly surgical patients exposed to beta-adrenergic antagonism
    • Shyong EQ Lucchinetti E Tagliente TM et al. Interleukin balance and early recovery from anesthesia in elderly surgical patients exposed to beta-adrenergic antagonism. J Clin Anesth 2003 15 : 170 178.
    • (2003) J Clin Anesth , vol.15 , pp. 170-178
    • Shyong, E.Q.1    Lucchinetti, E.2    Tagliente, T.M.3
  • 14
    • 0035894668 scopus 로고    scopus 로고
    • When human walking becomes random walking: Fractal analysis and modeling of gait rhythm fluctuations
    • Hausdorff JM Ashkenazy Y Peng CK et al. When human walking becomes random walking: Fractal analysis and modeling of gait rhythm fluctuations. Physica A 2001 302 : 138 147.
    • (2001) Physica a , vol.302 , pp. 138-147
    • Hausdorff, J.M.1    Ashkenazy, Y.2    Peng, C.K.3
  • 15
    • 19644372637 scopus 로고    scopus 로고
    • Gait instability and fractal dynamics of older adults with a 'cautious' gait: Why do certain older adults walk fearfully?
    • Herman T Giladi N Gurevich T et al. Gait instability and fractal dynamics of older adults with a 'cautious' gait: Why do certain older adults walk fearfully? Gait Posture 2005 21 : 178 185.
    • (2005) Gait Posture , vol.21 , pp. 178-185
    • Herman, T.1    Giladi, N.2    Gurevich, T.3
  • 16
    • 0037422564 scopus 로고    scopus 로고
    • Elevations of inflammatory and procoagulant biomarkers in elderly persons with renal insufficiency
    • Shlipak MG Fried LF Crump C et al. Elevations of inflammatory and procoagulant biomarkers in elderly persons with renal insufficiency. Circulation 2003 107 : 87 92.
    • (2003) Circulation , vol.107 , pp. 87-92
    • Shlipak, M.G.1    Fried, L.F.2    Crump, C.3
  • 17
    • 0034051068 scopus 로고    scopus 로고
    • Age-associated increased interleukin-6 gene expression, late-life diseases, and frailty
    • Ershler WB Keller ET. Age-associated increased interleukin-6 gene expression, late-life diseases, and frailty. Annu Rev Med 2000 51 : 245 270.
    • (2000) Annu Rev Med , vol.51 , pp. 245-270
    • Ershler, W.B.1    Keller, E.T.2
  • 18
    • 14644390741 scopus 로고    scopus 로고
    • What constitutes normal hemoglobin concentration in community-dwelling disabled older women?
    • Chaves PH Xue QL Guralnik JM et al. What constitutes normal hemoglobin concentration in community-dwelling disabled older women? J Am Geriatr Soc 2004 52 : 1811 1816.
    • (2004) J Am Geriatr Soc , vol.52 , pp. 1811-1816
    • Chaves, P.H.1    Xue, Q.L.2    Guralnik, J.M.3
  • 19
    • 0347511004 scopus 로고    scopus 로고
    • Emerging relationships of inflammation, cardiovascular disease and chronic diseases of aging
    • Tracy RP. Emerging relationships of inflammation, cardiovascular disease and chronic diseases of aging. Int J Obes Relat Metab Disord 2003 27 Suppl 3 : S29 S34.
    • (2003) Int J Obes Relat Metab Disord , vol.27 , Issue.3
    • Tracy, R.P.1
  • 20
    • 0027415150 scopus 로고
    • Sarcopenia and age-related changes in body composition and functional capacity
    • Evans WJ Campbell WW. Sarcopenia and age-related changes in body composition and functional capacity. J Nutr 1993 123 Suppl 2 : 465 468.
    • (1993) J Nutr , vol.123 , Issue.2 , pp. 465-468
    • Evans, W.J.1    Campbell, W.W.2
  • 22
    • 0036251818 scopus 로고    scopus 로고
    • Leg muscle mass and composition in relation to lower extremity performance in men and women aged 70 to 79: The Health, Aging and Body Composition Study
    • Visser M Kritchevsky SB Goodpaster BH et al. Leg muscle mass and composition in relation to lower extremity performance in men and women aged 70 to 79: The Health, Aging and Body Composition Study. J Am Geriatr Soc 2002 50 : 897 904.
    • (2002) J Am Geriatr Soc , vol.50 , pp. 897-904
    • Visser, M.1    Kritchevsky, S.B.2    Goodpaster, B.H.3
  • 23
    • 0036604165 scopus 로고    scopus 로고
    • Adipogenesis and aging: Does aging make fat go MAD?
    • Kirkland JL Tchkonia T Pirtskhalava T et al. Adipogenesis and aging: Does aging make fat go MAD? Exp Gerontol 2002 37 : 757 767.
    • (2002) Exp Gerontol , vol.37 , pp. 757-767
    • Kirkland, J.L.1    Tchkonia, T.2    Pirtskhalava, T.3
  • 24
    • 0036068710 scopus 로고    scopus 로고
    • Serum interleukin-6 and hemoglobin as physiological correlates in the geriatric syndrome of frailty: A pilot study
    • Leng S Chaves P Koenig K et al. Serum interleukin-6 and hemoglobin as physiological correlates in the geriatric syndrome of frailty: A pilot study. J Am Geriatr Soc 2002 50 : 1268 1271.
    • (2002) J Am Geriatr Soc , vol.50 , pp. 1268-1271
    • Leng, S.1    Chaves, P.2    Koenig, K.3
  • 25
    • 0034084305 scopus 로고    scopus 로고
    • Sarcopenic obesity. Does muscle loss cause fat gain? Lessons from rheumatoid arthritis and osteoarthritis
    • Roubenoff R. Sarcopenic obesity. Does muscle loss cause fat gain? Lessons from rheumatoid arthritis and osteoarthritis. Ann N Y Acad Sci 2000 904 : 553 557.
    • (2000) Ann N Y Acad Sci , vol.904 , pp. 553-557
    • Roubenoff, R.1
  • 26
    • 18944379924 scopus 로고    scopus 로고
    • Sarcopenic obesity predicts instrumental activities of daily living disability in the elderly
    • Baumgartner RN Wayne SJ Waters DL et al. Sarcopenic obesity predicts instrumental activities of daily living disability in the elderly. Obes Res 2004 12 : 1995 2004.
    • (2004) Obes Res , vol.12 , pp. 1995-2004
    • Baumgartner, R.N.1    Wayne, S.J.2    Waters, D.L.3
  • 27
    • 23444450084 scopus 로고    scopus 로고
    • The association between obesity and the frailty syndrome in older women: The Women's Health and Aging Studies
    • Blaum CS Xue QL Michelon E et al. The association between obesity and the frailty syndrome in older women: The Women's Health and Aging Studies. J Am Geriatr Soc 2005 53 : 927 934.
    • (2005) J Am Geriatr Soc , vol.53 , pp. 927-934
    • Blaum, C.S.1    Xue, Q.L.2    Michelon, E.3
  • 28
    • 0036482716 scopus 로고    scopus 로고
    • Cellular and molecular basis of age-related sarcopenia
    • Welle S. Cellular and molecular basis of age-related sarcopenia. Can J Appl Physiol 2002 27 : 19 41.
    • (2002) Can J Appl Physiol , vol.27 , pp. 19-41
    • Welle, S.1
  • 29
    • 0030789461 scopus 로고    scopus 로고
    • Influence of visual control, conduction, and central integration on static and dynamic balance in healthy older adults
    • Perrin PP Jeandel C Perrin CA et al. Influence of visual control, conduction, and central integration on static and dynamic balance in healthy older adults. Gerontology 1997 43 : 223 231.
    • (1997) Gerontology , vol.43 , pp. 223-231
    • Perrin, P.P.1    Jeandel, C.2    Perrin, C.A.3
  • 30
    • 0141531051 scopus 로고    scopus 로고
    • Influence of regular proprioceptive and bioenergetic physical activities on balance control in elderly women
    • Gauchard GC Gangloff P Jeandel C et al. Influence of regular proprioceptive and bioenergetic physical activities on balance control in elderly women. J Gerontol A Biol Sci Med Sci 2003 58A : M846 M850.
    • (2003) J Gerontol a Biol Sci Med Sci , vol.58
    • Gauchard, G.C.1    Gangloff, P.2    Jeandel, C.3
  • 31
    • 17144392613 scopus 로고    scopus 로고
    • Total and differential white blood cell counts and their associations with circulating interleukin-6 levels in community-dwelling older women
    • Leng S Bandeen-Roche K Huang Y et al. Total and differential white blood cell counts and their associations with circulating interleukin-6 levels in community-dwelling older women. J Gerontol A Biol Sci Med Sci 2005 60A : M195 M199.
    • (2005) J Gerontol a Biol Sci Med Sci , vol.60
    • Leng, S.1    Bandeen-Roche, K.2    Huang, Y.3
  • 32
    • 0141892842 scopus 로고    scopus 로고
    • Cytokines, insulin-like growth factor 1, sarcopenia, and mortality in very old community-dwelling men and women. the Framingham Heart Study
    • Roubenoff R Parise H Payette HA et al. Cytokines, insulin-like growth factor 1, sarcopenia, and mortality in very old community-dwelling men and women. The Framingham Heart Study. Am J Med 2003 115 : 429 435.
    • (2003) Am J Med , vol.115 , pp. 429-435
    • Roubenoff, R.1    Parise, H.2    Payette, H.A.3
  • 33
    • 0037927688 scopus 로고    scopus 로고
    • Catabolism of aging: Is it an inflammatory process?
    • Roubenoff R. Catabolism of aging: Is it an inflammatory process? Curr Opin Clin Nutr Metab Care 2003 6 : 295 299.
    • (2003) Curr Opin Clin Nutr Metab Care , vol.6 , pp. 295-299
    • Roubenoff, R.1
  • 34
    • 2642541669 scopus 로고    scopus 로고
    • Serum levels of insulin-like growth factor-I (IGF-I) and dehydroepiandrosterone sulfate (DHEA-S), and their relationships with serum interleukin-6, in the geriatric syndrome of frailty
    • Leng SX Cappola AR Andersen RE et al. Serum levels of insulin-like growth factor-I (IGF-I) and dehydroepiandrosterone sulfate (DHEA-S), and their relationships with serum interleukin-6, in the geriatric syndrome of frailty. Aging Clin Exp Res 2004 16 : 153 157.
    • (2004) Aging Clin Exp Res , vol.16 , pp. 153-157
    • Leng, S.X.1    Cappola, A.R.2    Andersen, R.E.3
  • 35
    • 0038369150 scopus 로고    scopus 로고
    • Insulin-like growth factor I and interleukin-6 contribute synergistically to disability and mortality in older women
    • Cappola AR Xue QL Ferrucci L et al. Insulin-like growth factor I and interleukin-6 contribute synergistically to disability and mortality in older women. J Clin Endocrinol Metab 2003 88 : 2019 2025.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 2019-2025
    • Cappola, A.R.1    Xue, Q.L.2    Ferrucci, L.3
  • 36
    • 3242676731 scopus 로고    scopus 로고
    • Dehydroepiandrosterone-sulfate inhibits nuclear factor-kappaB-dependent transcription in hepatocytes, possibly through antioxidant effect
    • Iwasaki Y Asai M Yoshida M et al. Dehydroepiandrosterone-sulfate inhibits nuclear factor-kappaB-dependent transcription in hepatocytes, possibly through antioxidant effect. J Clin Endocrinol Metab 2004 89 : 3449 3454.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 3449-3454
    • Iwasaki, Y.1    Asai, M.2    Yoshida, M.3
  • 37
    • 0027320859 scopus 로고
    • Insulin-like growth factor-1 activity is inhibited by interleukin-1 alpha, tumor necrosis factor-alpha, and interleukin-6
    • Lazarus DD Moldawer LL Lowry SF. Insulin-like growth factor-1 activity is inhibited by interleukin-1 alpha, tumor necrosis factor-alpha, and interleukin-6. Lymphokine Cytokine Res 1993 12 : 219 223.
    • (1993) Lymphokine Cytokine Res , vol.12 , pp. 219-223
    • Lazarus, D.D.1    Moldawer, L.L.2    Lowry, S.F.3
  • 38
    • 0031963046 scopus 로고    scopus 로고
    • The pathophysiologic roles of interleukin-6 in human disease
    • Papanicolaou DA Wilder RL Manolagas SC et al. The pathophysiologic roles of interleukin-6 in human disease. Ann Intern Med 1998 128 : 127 137.
    • (1998) Ann Intern Med , vol.128 , pp. 127-137
    • Papanicolaou, D.A.1    Wilder, R.L.2    Manolagas, S.C.3
  • 39
    • 0038544188 scopus 로고    scopus 로고
    • Oxidative stress, chromatin remodeling and gene transcription in inflammation and chronic lung diseases
    • Rahman I. Oxidative stress, chromatin remodeling and gene transcription in inflammation and chronic lung diseases. J Biochem Mol Biol 2003 36 : 95 109.
    • (2003) J Biochem Mol Biol , vol.36 , pp. 95-109
    • Rahman, I.1
  • 40
    • 0033570271 scopus 로고    scopus 로고
    • Oxidative stress as a regulator of gene expression in the vasculature
    • Kunsch C Medford RM. Oxidative stress as a regulator of gene expression in the vasculature. Circ Res 1999 85 : 753 766.
    • (1999) Circ Res , vol.85 , pp. 753-766
    • Kunsch, C.1    Medford, R.M.2
  • 41
    • 0036985417 scopus 로고    scopus 로고
    • The mitochondrial theory of aging: Involvement of mitochondrial DNA damage and repair
    • Souza-Pinto NC Bohr VA. The mitochondrial theory of aging: Involvement of mitochondrial DNA damage and repair. Int Rev Neurobiol 2002 53 : 519 534.
    • (2002) Int Rev Neurobiol , vol.53 , pp. 519-534
    • Souza-Pinto, N.C.1    Bohr, V.A.2
  • 42
    • 0141763835 scopus 로고    scopus 로고
    • Telomere maintenance and disease
    • Wong JM Collins K. Telomere maintenance and disease. Lancet 2003 362 : 983 988.
    • (2003) Lancet , vol.362 , pp. 983-988
    • Wong, J.M.1    Collins, K.2
  • 43
    • 0037308404 scopus 로고    scopus 로고
    • Association between telomere length in blood and mortality in people aged 60 years or older
    • Cawthon RM Smith KR O'Brien E et al. Association between telomere length in blood and mortality in people aged 60 years or older. Lancet 2003 361 : 393 395.
    • (2003) Lancet , vol.361 , pp. 393-395
    • Cawthon, R.M.1    Smith, K.R.2    O'Brien, E.3
  • 44
    • 0037238101 scopus 로고    scopus 로고
    • Cellular senescence and apoptosis: How cellular responses might influence aging phenotypes
    • Campisi J. Cellular senescence and apoptosis: How cellular responses might influence aging phenotypes. Exp Gerontol 2003 38 : 5 11.
    • (2003) Exp Gerontol , vol.38 , pp. 5-11
    • Campisi, J.1
  • 45
    • 0141720388 scopus 로고    scopus 로고
    • Calorie restriction and aging: Review of the literature and implications for studies in humans
    • Heilbronn LK Ravussin E. Calorie restriction and aging: Review of the literature and implications for studies in humans. Am J Clin Nutr 2003 78 : 361 369.
    • (2003) Am J Clin Nutr , vol.78 , pp. 361-369
    • Heilbronn, L.K.1    Ravussin, E.2
  • 46
    • 15944404290 scopus 로고    scopus 로고
    • Exogenous testosterone (T) alone or with finasteride increases physical performance, grip strength, and lean body mass in older men with low serum T
    • Page ST Amory JK Bowman FD et al. Exogenous testosterone (T) alone or with finasteride increases physical performance, grip strength, and lean body mass in older men with low serum T. J Clin Endocrinol Metab 2005 90 : 1502 1510.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 1502-1510
    • Page, S.T.1    Amory, J.K.2    Bowman, F.D.3
  • 47
    • 0037463821 scopus 로고    scopus 로고
    • Effect of 1-year oral administration of dehydroepiandrosterone to 60- to 80-year-old individuals on muscle function and cross-sectional area: A double-blind placebo-controlled trial
    • Percheron G Hogrel JY Denot-Ledunois S et al. Effect of 1-year oral administration of dehydroepiandrosterone to 60- to 80-year-old individuals on muscle function and cross-sectional area: A double-blind placebo-controlled trial. Arch Intern Med 2003 163 : 720 727.
    • (2003) Arch Intern Med , vol.163 , pp. 720-727
    • Percheron, G.1    Hogrel, J.Y.2    Denot-Ledunois, S.3
  • 48
    • 5444234867 scopus 로고    scopus 로고
    • Erythropoietin: Novel approaches to neuroprotection in human brain disease
    • Ehrenreich H Aust C Krampe H et al. Erythropoietin: Novel approaches to neuroprotection in human brain disease. Metab Brain Dis 2004 19 : 195 206.
    • (2004) Metab Brain Dis , vol.19 , pp. 195-206
    • Ehrenreich, H.1    Aust, C.2    Krampe, H.3
  • 49
    • 0842329753 scopus 로고    scopus 로고
    • Erythropoietin: A candidate compound for neuroprotection in schizophrenia
    • Ehrenreich H Degner D Meller J et al. Erythropoietin: A candidate compound for neuroprotection in schizophrenia. Mol Psychiatry 2004 9 : 42 54.
    • (2004) Mol Psychiatry , vol.9 , pp. 42-54
    • Ehrenreich, H.1    Degner, D.2    Meller, J.3
  • 50
    • 0037117109 scopus 로고    scopus 로고
    • Relation between use of angiotensin-converting enzyme inhibitors and muscle strength and physical function in older women: An observational study
    • Onder G Penninx BW Balkrishnan R et al. Relation between use of angiotensin-converting enzyme inhibitors and muscle strength and physical function in older women: An observational study. Lancet 2002 359 : 926 930.
    • (2002) Lancet , vol.359 , pp. 926-930
    • Onder, G.1    Penninx, B.W.2    Balkrishnan, R.3
  • 51
    • 0028341292 scopus 로고
    • Exercise training and nutritional supplementation for physical frailty in very elderly people
    • Fiatarone MA O'Neill EF Ryan ND et al. Exercise training and nutritional supplementation for physical frailty in very elderly people. N Engl J Med 1994 330 : 1769 1775.
    • (1994) N Engl J Med , vol.330 , pp. 1769-1775
    • Fiatarone, M.A.1    O'Neill, E.F.2    Ryan, N.D.3
  • 52
    • 0037015543 scopus 로고    scopus 로고
    • A program to prevent functional decline in physically frail, elderly persons who live at home
    • Gill TM Baker DI Gottschalk M et al. A program to prevent functional decline in physically frail, elderly persons who live at home. N Engl J Med 2002 347 : 1068 1074.
    • (2002) N Engl J Med , vol.347 , pp. 1068-1074
    • Gill, T.M.1    Baker, D.I.2    Gottschalk, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.