Quercetin prevents pyrrolizidine alkaloid clivorine-induced liver injury in mice by elevating body defense capacity

PLoS ONE

Volumn 9, Issue 6, 2014, Pages

  Ji, Lili ^a,b   Ma, Yibo ^a   Wang, Zaiyong ^b   Cai, Zhunxiu ^a   Pang, Chun ^a   Wang, Zhengtao ^a,b  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b Shanghai R and D Centre for Standardization of Chinese Medicines   (China)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYNONENAL; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; CASPASE 3; CLIVORINE; GLUTATHIONE; MALONALDEHYDE; MESSENGER RNA; QUERCETIN; PYRROLIZIDINE ALKALOID;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILIRUBIN BLOOD LEVEL; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG MECHANISM; ENZYME ACTIVATION; GENE EXPRESSION; HEAT SHOCK; HISTOPATHOLOGY; IMMUNITY; IMMUNOHISTOCHEMISTRY; LIPID PEROXIDATION; LIVER INJURY; LIVER LEVEL; LIVER PARENCHYMA; LIVER PROTECTION; MALE; METABOLIC STRESS; MOUSE; NICK END LABELING; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ANIMAL; CELL PROTECTION; DRUG EFFECTS; DRUG-INDUCED LIVER INJURY; IMMUNOLOGY; INSTITUTE FOR CANCER RESEARCH MOUSE; LIVER; METABOLISM; OXIDATION REDUCTION REACTION; PATHOLOGY; TOXICITY;

ANIMALS; APOPTOSIS; CYTOPROTECTION; DRUG-INDUCED LIVER INJURY; LIVER; MALE; MICE; MICE, INBRED ICR; OXIDATION-REDUCTION; OXIDATIVE STRESS; PYRROLIZIDINE ALKALOIDS; QUERCETIN;

EID: 84902578828     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0098970     Document Type: Article

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