Pyrrolizidine alkaloid clivorine induced oxidative injury on primary cultured rat hepatocytes

Human and Experimental Toxicology

Volumn 29, Issue 4, 2010, Pages 303-309

  Ji, Li ^a,b   Liu, Tian Yu ^a   Wang, Zheng Tao ^a,b  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b Shanghai R and D Centre for Standardization of Chinese Medicines   (China)

Author keywords

Antioxidant enzymes; Clivorine; Hepatotoxic pyrrolizidine alkaloid; Oxidative stress; Rat hepatocytes

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CATALASE; CLIVORINE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DAMAGE; CELL ISOLATION; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; ENZYME ASSAY; HUMAN; HUMAN CELL; LIPID PEROXIDATION; LIVER CELL; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ANIMALS; ASTERACEAE; CATALASE; CELL CULTURE TECHNIQUES; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; HEPATOCYTES; HUMANS; LIPID PEROXIDATION; OXIDATION-REDUCTION; OXIDATIVE STRESS; PYRROLIZIDINE ALKALOIDS; RATS; RATS, SPRAGUE-DAWLEY; SUPEROXIDE DISMUTASE; TIME FACTORS;

RATTUS;

EID: 77949884959     PISSN: 09603271     EISSN: 14770903     Source Type: Journal    
DOI: 10.1177/0960327110361757     Document Type: Article

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