Pyrrolizidine alkaloid clivorine inhibits human normal liver L-02 cells growth and activates p38 mitogen-activated protein kinase in L-02 cells

Toxicon

Volumn 40, Issue 12, 2002, Pages 1685-1690

  Ji, Li Li ^a,b   Zhao, Xian Guo ^a   Chen, Li ^b   Zhang, Mian ^a   Wang, Zheng Tao ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

Author keywords

Clivorine; L 02 cell; p38 Mitogen activated protein kinase; Pyrrolizidine alkaloid

Indexed keywords

CLIVORINE; ISOENZYME; LIGULARIA HODGSONII EXTRACT; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCROTALINE; PLANT EXTRACT; UNCLASSIFIED DRUG;

ARTICLE; CELL GROWTH; CELL PROLIFERATION; CELL VIABILITY; CHINA; CONTROLLED STUDY; DRUG EFFECT; HUMAN; HUMAN CELL; LIVER CELL; MEDICINAL PLANT; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

BLOTTING, WESTERN; CELL DIVISION; CELL SURVIVAL; ENZYME ACTIVATION; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HELA CELLS; HUMANS; LIVER; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; MONOCROTALINE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PYRROLIZIDINE ALKALOIDS; TETRAZOLIUM SALTS; THIAZOLES; TIME FACTORS;

LIGULARIA; LIGULARIA HODGSONII;

EID: 0036891360     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0041-0101(02)00184-8     Document Type: Article

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