Fullerene derivatives as a new class of inhibitors of protein tyrosine phosphatases

Bioorganic and Medicinal Chemistry Letters

Volumn 24, Issue 14, 2014, Pages 3175-3179

  Kobzar, Oleksandr L ^a   Trush, Viacheslav V ^a   Tanchuk, Vsevolod Yu ^a   Zhilenkov, Alexander V ^b   Troshin, Pavel A ^b   Vovk, Andriy I ^a  

^a INSTITUTE OF BIOORGANIC CHEMISTRY AND PETROCHEMISTRY   (Ukraine)

^b INSTITUTE OF PROBLEMS OF CHEMICAL PHYSICS   (Russian Federation)

Author keywords

Fullerene; Inhibition; Molecular docking; Protein tyrosine phosphatase

Indexed keywords

CD45 ANTIGEN; FULLERENE DERIVATIVE; NON RECEPTOR PROTEIN TYROSINE PHOSPHATASE 2; PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE 1B; PROTEIN TYROSINE PHOSPHATASE BETA; PROTEIN TYROSINE PHOSPHATASE INHIBITOR; PROTEIN TYROSINE PHOSPHATASE SHP 2; UNCLASSIFIED DRUG; ENZYME INHIBITOR;

ARTICLE; DRUG DESIGN; IC 50; ANTAGONISTS AND INHIBITORS; CHEMISTRY; CONFORMATION; DOSE RESPONSE; HUMAN; METABOLISM; STRUCTURE ACTIVITY RELATION;

DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; FULLERENES; HUMANS; MOLECULAR CONFORMATION; PROTEIN TYROSINE PHOSPHATASES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84902549136     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2014.04.110     Document Type: Article

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