-
1
-
-
0038771965
-
The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling
-
Neel BG, Gu H, Pao L. The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling. Trends Biochem Sci. 2003;28:284-293.
-
(2003)
Trends Biochem Sci
, vol.28
, pp. 284-293
-
-
Neel, B.G.1
Gu, H.2
Pao, L.3
-
3
-
-
0033761488
-
The tyrosine phosphatase SHP-2 is required for sustained activation of extracellular signal-regulated kinase and epithelial morphogenesis downstream from the Met receptor tyrosine kinase
-
Maroun CR, Naujokas MA, Holgado-Madruga M, Wong A, Park M. The tyrosine phosphatase SHP-2 is required for sustained activation of extracellular signal-regulated kinase and epithelial morphogenesis downstream from the Met receptor tyrosine kinase. Mol Cell Biol. 2000;20:8513-8525.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 8513-8525
-
-
Maroun, C.R.1
Naujokas, M.A.2
Holgado-Madruga, M.3
Wong, A.4
Park, M.5
-
4
-
-
0033965899
-
Molecular mechanism for the Shp-2 tyrosine phosphatase function in promoting growth factor stimulation of Erk activity
-
Shi Z-Q, Yu D-H, Park M, Marshall M, Feng G-S. Molecular mechanism for the Shp-2 tyrosine phosphatase function in promoting growth factor stimulation of Erk activity. Mol Cell Biol. 2000;20:1526-1536.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 1526-1536
-
-
Shi, Z.-Q.1
Yu, D.-H.2
Park, M.3
Marshall, M.4
Feng, G.-S.5
-
5
-
-
0142059890
-
Molecular mechanism for a role of SHP-2 in epidermal growth factor receptor signaling
-
Agazie YM, Hayman MJ. Molecular mechanism for a role of SHP-2 in epidermal growth factor receptor signaling. Mol Cell Biol. 2003;23:7875-7886.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 7875-7886
-
-
Agazie, Y.M.1
Hayman, M.J.2
-
6
-
-
0141730311
-
Catalytic-dependent and -independent roles of SHP-2 tyrosine phosphatase in interleukin-3 signaling
-
Yu WM, Hawley TS, Hawley RG, Qu CK. Catalytic-dependent and -independent roles of SHP-2 tyrosine phosphatase in interleukin-3 signaling. Oncogene. 2003;22:5995-6004.
-
(2003)
Oncogene
, vol.22
, pp. 5995-6004
-
-
Yu, W.M.1
Hawley, T.S.2
Hawley, R.G.3
Qu, C.K.4
-
7
-
-
0028878979
-
The SH2-containing protein-tyrosine phosphatase SH-PTP2 is required upstream of MAP kinase for early Xenopus development
-
Tang TL, Freeman RM Jr, O'Reilly AM, Neel BG, Sokol SY. The SH2-containing protein-tyrosine phosphatase SH-PTP2 is required upstream of MAP kinase for early Xenopus development. Cell. 1995;80:473-483.
-
(1995)
Cell
, vol.80
, pp. 473-483
-
-
Tang, T.L.1
Freeman Jr., R.M.2
O'Reilly, A.M.3
Neel, B.G.4
Sokol, S.Y.5
-
8
-
-
0030921502
-
Abnormal mesoderm pattering in mouse embryos mutant for the SH2 tyrosine phosphatase Shp-2
-
Saxton TM, Henkemeyer M, Gasca S, et al. Abnormal mesoderm pattering in mouse embryos mutant for the SH2 tyrosine phosphatase Shp-2. EMBO J. 1997;16:2352-2364.
-
(1997)
EMBO J
, vol.16
, pp. 2352-2364
-
-
Saxton, T.M.1
Henkemeyer, M.2
Gasca, S.3
-
9
-
-
0031708674
-
Biased suppression of hematopoiesis and multiple developmental defects in chimeric mice containing Shp-2 mutant cells
-
Qu C-K, Yu W-M, Azzarelli B, Cooper S, Broxmeyer HE, Feng G-S. Biased suppression of hematopoiesis and multiple developmental defects in chimeric mice containing Shp-2 mutant cells. Mol Cell Biol. 1998;18:6075-6082.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 6075-6082
-
-
Qu, C.-K.1
Yu, W.-M.2
Azzarelli, B.3
Cooper, S.4
Broxmeyer, H.E.5
Feng, G.-S.6
-
10
-
-
0034127009
-
The SH2 tyrosine phosphatase Shp2 is required for mammalian limb development
-
Saxton TM, Ciruna BG, Holmyard D, et al. The SH2 tyrosine phosphatase Shp2 is required for mammalian limb development. Nat Genet. 2000;24:420-423.
-
(2000)
Nat Genet
, vol.24
, pp. 420-423
-
-
Saxton, T.M.1
Ciruna, B.G.2
Holmyard, D.3
-
11
-
-
0034091647
-
Mice mutants for Egfr and Shp2 have defective cardiac semilunar valvulogenesis
-
Chen B, Bronson RT, Klaman LD, et al. Mice mutants for Egfr and Shp2 have defective cardiac semilunar valvulogenesis. Nat Genet. 2000;24:296-299.
-
(2000)
Nat Genet
, vol.24
, pp. 296-299
-
-
Chen, B.1
Bronson, R.T.2
Klaman, L.D.3
-
12
-
-
0030797548
-
A deletion mutation in the SH2-N domain of Shp-2 severely suppresses hematopoietic cell development
-
Qu CK, Shi ZQ, Shen R, Tsai FY, Orkin SH, Feng GS. A deletion mutation in the SH2-N domain of Shp-2 severely suppresses hematopoietic cell development. Mol Cell Biol. 1997;17:5499-5507.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 5499-5507
-
-
Qu, C.K.1
Shi, Z.Q.2
Shen, R.3
Tsai, F.Y.4
Orkin, S.H.5
Feng, G.S.6
-
13
-
-
0035865690
-
Requirement of Shp-2 tyrosine phosphatase in lymphoid and hematopoietic cell development
-
Qu C-K, Nguyen S, Chen J, Feng G-S. Requirement of Shp-2 tyrosine phosphatase in lymphoid and hematopoietic cell development. Blood. 2001;97:911-914.
-
(2001)
Blood
, vol.97
, pp. 911-914
-
-
Qu, C.-K.1
Nguyen, S.2
Chen, J.3
Feng, G.-S.4
-
14
-
-
0141567655
-
A definitive role of Shp-2 tyrosine phosphatase in mediating embryonic stem cell differentiation and hematopoiesis
-
Chan RJ, Johnson SA, Li Y, Yoder MC, Feng GS. A definitive role of Shp-2 tyrosine phosphatase in mediating embryonic stem cell differentiation and hematopoiesis. Blood. 2003;102:2074-2080.
-
(2003)
Blood
, vol.102
, pp. 2074-2080
-
-
Chan, R.J.1
Johnson, S.A.2
Li, Y.3
Yoder, M.C.4
Feng, G.S.5
-
15
-
-
18344385476
-
Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome
-
Tartaglia M, Mehler EL, Goldberg R, et al. Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome. Nat Genet. 2001;29:465-468.
-
(2001)
Nat Genet
, vol.29
, pp. 465-468
-
-
Tartaglia, M.1
Mehler, E.L.2
Goldberg, R.3
-
16
-
-
18344370436
-
PTPN11 mutations in Noonan syndrome: Molecular spectrum, genotype-phenotype correlation, and phenotypic heterogeneity
-
Tartaglia M, Kalidas K, Shaw A, et al. PTPN11 mutations in Noonan syndrome: molecular spectrum, genotype-phenotype correlation, and phenotypic heterogeneity. Am J Hum Genet. 2002;70:1555-1563.
-
(2002)
Am J Hum Genet
, vol.70
, pp. 1555-1563
-
-
Tartaglia, M.1
Kalidas, K.2
Shaw, A.3
-
17
-
-
3142524901
-
PTPN11 and the Noonan syndrome
-
Epstein CJ, Erickson RP, Wynshaw-Boris A, eds. San Francisco, CA: Oxford University Press
-
Tartaglia M, Gelb BD. PTPN11 and the Noonan syndrome. In: Epstein CJ, Erickson RP, Wynshaw-Boris A, eds. Inborn Errors of Development. The Molecular Basis of Clinical Disorders of Morphogenesis. San Francisco, CA: Oxford University Press; 2004:895-903.
-
(2004)
Inborn Errors of Development. The Molecular Basis of Clinical Disorders of Morphogenesis
, pp. 895-903
-
-
Tartaglia, M.1
Gelb, B.D.2
-
18
-
-
0030712155
-
Occurrence of myeloproliferative disorder in patients with Noonan syndrome
-
Bader-Meunier B, Tchernia G, Miélot F, et al. Occurrence of myeloproliferative disorder in patients with Noonan syndrome. J Pediatr. 1997;130:885-889.
-
(1997)
J Pediatr
, vol.130
, pp. 885-889
-
-
Bader-Meunier, B.1
Tchernia, G.2
Miélot, F.3
-
19
-
-
0031086478
-
Spontaneous remission of JCML in an infant with NS
-
Fukuda M, Horibe K, Miyajima Y, Matsumoto K, Nagashima M. Spontaneous remission of JCML in an infant with NS. J Pediatr Hematol Oncol. 1997;19:177-178.
-
(1997)
J Pediatr Hematol Oncol
, vol.19
, pp. 177-178
-
-
Fukuda, M.1
Horibe, K.2
Miyajima, Y.3
Matsumoto, K.4
Nagashima, M.5
-
20
-
-
0033504544
-
Juvenile myelomonocytic leukemia and Noonan syndrome
-
Choong K, Freedman MH, Chitayat D, Kelly EN, Taylor G, Zipursky A. Juvenile myelomonocytic leukemia and Noonan syndrome. J Pediatr Hematol Oncol. 1999;21:523-527.
-
(1999)
J Pediatr Hematol Oncol
, vol.21
, pp. 523-527
-
-
Choong, K.1
Freedman, M.H.2
Chitayat, D.3
Kelly, E.N.4
Taylor, G.5
Zipursky, A.6
-
21
-
-
0027198793
-
Acute lymphoblastic leukemia in Noonan syndrome: Report of two cases
-
Piombo M, Rosanda C, Pasino M, Marasini M, Cerruti P, Comelli A. Acute lymphoblastic leukemia in Noonan syndrome: report of two cases. Med Pediatr Oncol. 1993;21:454-455.
-
(1993)
Med Pediatr Oncol
, vol.21
, pp. 454-455
-
-
Piombo, M.1
Rosanda, C.2
Pasino, M.3
Marasini, M.4
Cerruti, P.5
Comelli, A.6
-
24
-
-
0038278866
-
Somatic PTPN11 mutations in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia
-
Tartagiia M, Niemeyer CM, Fragale A, et al. Somatic PTPN11 mutations in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia. Nat Genet. 2003;34:148-150.
-
(2003)
Nat Genet
, vol.34
, pp. 148-150
-
-
Tartagiia, M.1
Niemeyer, C.M.2
Fragale, A.3
-
25
-
-
12144286410
-
Somatic mutations in PTPN11 implicate the protein tyrosine phosphatase SHP-2 in leukemogenesis
-
Prepublished on November 26, as DOI 10.1182/blood-2003-09-3287
-
Loh ML, Vattikuti S, Schubbert S, et al. Somatic mutations in PTPN11 implicate the protein tyrosine phosphatase SHP-2 in leukemogenesis. Blood. Prepublished on November 26, 2003, as DOI 10.1182/blood-2003-09-3287. (Now available as Blood. 2004;103:2325-2331.)
-
(2003)
Blood
-
-
Loh, M.L.1
Vattikuti, S.2
Schubbert, S.3
-
26
-
-
12144286410
-
-
Loh ML, Vattikuti S, Schubbert S, et al. Somatic mutations in PTPN11 implicate the protein tyrosine phosphatase SHP-2 in leukemogenesis. Blood. Prepublished on November 26, 2003, as DOI 10.1182/blood-2003-09-3287. (Now available as Blood. 2004;103:2325-2331.)
-
(2004)
Blood
, vol.103
, pp. 2325-2331
-
-
-
28
-
-
0032757710
-
Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual disease. Report of the BIOMED-1 Concerted Action: Investigation of minimal residual disease in acute leukemia
-
van Dongen JJ, Macintyre EA, Gabert JA, et al. Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual disease. Report of the BIOMED-1 Concerted Action: investigation of minimal residual disease in acute leukemia. Leukemia. 1999;13:1901-1928.
-
(1999)
Leukemia
, vol.13
, pp. 1901-1928
-
-
Van Dongen, J.J.1
Macintyre, E.A.2
Gabert, J.A.3
-
29
-
-
0021159632
-
Convention on nomenclature for DNA cytometry
-
Committee on Nomenclature, Society for Analytical Cytology
-
Hiddemann W, Schumann J, Andreef M, et al. Convention on nomenclature for DNA cytometry. Committee on Nomenclature, Society for Analytical Cytology. Cancer Genet Cytogenet. 1984;13:181-183.
-
(1984)
Cancer Genet Cytogenet
, vol.13
, pp. 181-183
-
-
Hiddemann, W.1
Schumann, J.2
Andreef, M.3
-
30
-
-
0032548830
-
Crystal structure of the tyrosine phosphatase SHP-2
-
Hof P, Pluskey S, Dhe-Paganon S, Eck MJ, Shoelson SE. Crystal structure of the tyrosine phosphatase SHP-2. Cell. 1998;92:441-450.
-
(1998)
Cell
, vol.92
, pp. 441-450
-
-
Hof, P.1
Pluskey, S.2
Dhe-Paganon, S.3
Eck, M.J.4
Shoelson, S.E.5
-
31
-
-
13344282725
-
TEL/AML1 fusion resulting from a cryptic t(12;21) is the most common genetic lesion in pediatric ALL and defines a subgroup of patients with an excellent prognosis
-
Shurtleff SA, Buijs A, Behm FG, et al. TEL/AML1 fusion resulting from a cryptic t(12;21) is the most common genetic lesion in pediatric ALL and defines a subgroup of patients with an excellent prognosis. Leukemia. 1995;9:1985-1989.
-
(1995)
Leukemia
, vol.9
, pp. 1985-1989
-
-
Shurtleff, S.A.1
Buijs, A.2
Behm, F.G.3
-
32
-
-
0030742318
-
Src homology 2 protein tyrosine phosphatase (SH PTP2)/Src homology 2 phosphatase 2 (SHP2) tyrosine phosphatase is a positive regulator of the interleukin 5 receptor signal transduction pathways leading to the prolongation of eosinophil survival
-
Pazdrak K, Adachi T, Alam R. Src homology 2 protein tyrosine phosphatase (SH PTP2)/Src homology 2 phosphatase 2 (SHP2) tyrosine phosphatase is a positive regulator of the interleukin 5 receptor signal transduction pathways leading to the prolongation of eosinophil survival. J Exp Med. 1997;186:561-568.
-
(1997)
J Exp Med
, vol.186
, pp. 561-568
-
-
Pazdrak, K.1
Adachi, T.2
Alam, R.3
-
33
-
-
0034623059
-
SHP2 mediates the protective effect of interleukin-6 against dexamethasone-induced apoptosis in multiple myeloma cells
-
Chauhan D, Pandey P, Hideshima T, et al. SHP2 mediates the protective effect of interleukin-6 against dexamethasone-induced apoptosis in multiple myeloma cells. J Biol Chem. 2000;275:27845-27850.
-
(2000)
J Biol Chem
, vol.275
, pp. 27845-27850
-
-
Chauhan, D.1
Pandey, P.2
Hideshima, T.3
-
34
-
-
0141730311
-
Catalytic-dependent and -independent roles of SHP-2 tyrosine phosphatase in interleukin-3 signaling
-
Yu WM, Hawley TS, Hawley RG, Qu CK. Catalytic-dependent and -independent roles of SHP-2 tyrosine phosphatase in interleukin-3 signaling. Oncogene. 2003;22:5995-6004.
-
(2003)
Oncogene
, vol.22
, pp. 5995-6004
-
-
Yu, W.M.1
Hawley, T.S.2
Hawley, R.G.3
Qu, C.K.4
-
35
-
-
0031870590
-
Mutational analysis of the N-ras gene in acute lymphoblastic leukemia: A study of 125 Japanese pediatric cases
-
Yokota S, Nakao M, Horiike S, et al. Mutational analysis of the N-ras gene in acute lymphoblastic leukemia: a study of 125 Japanese pediatric cases. Int J Hematol. 1998;67:379-387.
-
(1998)
Int J Hematol
, vol.67
, pp. 379-387
-
-
Yokota, S.1
Nakao, M.2
Horiike, S.3
-
36
-
-
0025254225
-
N-Ras gene point mutations in childhood acute lymphocytic leukemia correlate with a poor prognosis
-
Lübbert M, Mirro J Jr, Miller CW, et al. N-Ras gene point mutations in childhood acute lymphocytic leukemia correlate with a poor prognosis. Blood. 1990;75:1163-1169.
-
(1990)
Blood
, vol.75
, pp. 1163-1169
-
-
Lübbert, M.1
Mirro Jr., J.2
Miller, C.W.3
-
37
-
-
0025240615
-
The pattern of mutational involvement of RAS genes in human hematologic malignancies determined by DNA amplification and direct sequencing
-
Ahuja HG, Foti A, Bar-Eli M, Cline MJ. The pattern of mutational involvement of RAS genes in human hematologic malignancies determined by DNA amplification and direct sequencing. Blood. 1990;75:1684-1690.
-
(1990)
Blood
, vol.75
, pp. 1684-1690
-
-
Ahuja, H.G.1
Foti, A.2
Bar-Eli, M.3
Cline, M.J.4
-
38
-
-
1542619343
-
Noonan syndrome-associated SHP-2/PTPN11 mutants cause EGF-dependent prolonged GAB1 binding and sustained ERK2/MAPK1 activation
-
Fragale A, Tartaglia M, Wu J, Gelb BD. Noonan syndrome-associated SHP-2/PTPN11 mutants cause EGF-dependent prolonged GAB1 binding and sustained ERK2/MAPK1 activation. Hum Mut. 2004;23:267-277.
-
(2004)
Hum Mut
, vol.23
, pp. 267-277
-
-
Fragale, A.1
Tartaglia, M.2
Wu, J.3
Gelb, B.D.4
-
39
-
-
0036074033
-
Grouping of multiple-lentigines/LEOPARD and Noonan syndromes on the PTPN11 gene
-
Digilio MC, Conti E, Sarkozy A, et al. Grouping of multiple-lentigines/ LEOPARD and Noonan syndromes on the PTPN11 gene. Am J Hum Genet. 2002;71:389-394.
-
(2002)
Am J Hum Genet
, vol.71
, pp. 389-394
-
-
Digilio, M.C.1
Conti, E.2
Sarkozy, A.3
-
41
-
-
0031718359
-
Regulation of proliferation, differentiation and survival by the IL-3/IL-5/GM-CSF receptor family
-
de Groot RP, Coffer PJ, Koenderman L. Regulation of proliferation, differentiation and survival by the IL-3/IL-5/GM-CSF receptor family. Cell Signal. 1998;10:619-628.
-
(1998)
Cell Signal
, vol.10
, pp. 619-628
-
-
De Groot, R.P.1
Coffer, P.J.2
Koenderman, L.3
-
42
-
-
0033113275
-
Cytokine signaling for proliferation, survival, and death in hematopoietic cells
-
Miyajima A, Ito Y, Kinoshita T. Cytokine signaling for proliferation, survival, and death in hematopoietic cells. Int J Hematol. 1999;69:137-146.
-
(1999)
Int J Hematol
, vol.69
, pp. 137-146
-
-
Miyajima, A.1
Ito, Y.2
Kinoshita, T.3
-
43
-
-
0037810249
-
Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: Potential targeting for therapeutic intervention
-
Chang F, Steelman LS, Lee JT, et al. Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention. Leukemia. 2003;17:1263-1293.
-
(2003)
Leukemia
, vol.17
, pp. 1263-1293
-
-
Chang, F.1
Steelman, L.S.2
Lee, J.T.3
-
44
-
-
0031937682
-
The molecular pathophysiology of myeloid leukaemias: Ras revisited
-
Byrne JL, Marshall CJ. The molecular pathophysiology of myeloid leukaemias: Ras revisited. Br J Haematol. 1998;100:256-264.
-
(1998)
Br J Haematol
, vol.100
, pp. 256-264
-
-
Byrne, J.L.1
Marshall, C.J.2
|