α,α-Difluoro-β-ketophosphonates as potent inhibitors of protein tyrosine phosphatase 1B

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 16, 2004, Pages 4301-4306

  Li, Xianfeng ^a,b   Bhandari, Ashok ^a   Holmes, Christopher P ^a   Szardenings, Anna K ^a,c  

^a AFFYMAX RESEARCH INSTITUTE   (United States)

^b Galileo Laboratories Inc   (United States)

^c ACTIVX BIOSCIENCES INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA,ALPHA DIFLUORO BETA KETOPHOSPHONATE; PHOSPHONIC ACID DERIVATIVE; PROTEIN TYROSINE PHOSPHATASE; UNCLASSIFIED DRUG;

ARTICLE; ENZYME ACTIVITY; ENZYME INHIBITION; EVALUATION; STRUCTURE ANALYSIS; SYNTHESIS;

CATALYSIS; ENZYME INHIBITORS; PHOSPHONIC ACIDS; PROTEIN-TYROSINE-PHOSPHATASE;

EID: 3142763040     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.05.082     Document Type: Article

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