Inhibition of PTP1B by trodusquemine (MSI-1436) causes fat-specific weight loss in diet-induced obese mice

Obesity

Volumn 18, Issue 8, 2010, Pages 1516-1523

  Lantz, Kristen A ^a   Hart, Susan G Emeigh ^a   Planey, Sonia L ^a   Roitman, Mitchell F ^b   Ruiz White, Inez A ^a   Wolfe, Henry R ^a   McLane, Michael P ^a  

^a Genaera Corporation   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 N 1(SPERMINE) 7, 24 DIHYDROXY 5 CHOLESTANE 24 SULFATE; 3-N-1(SPERMINE)-7, 24-DIHYDROXY-5-CHOLESTANE 24-SULFATE; ANTILIPEMIC AGENT; CHOLESTANE DERIVATIVE; DRUG DERIVATIVE; INSULIN; INSULIN RECEPTOR; LEPTIN; PROTEIN TYROSINE PHOSPHATASE 1B; SPERMINE; STAT3 PROTEIN; STAT3 PROTEIN, MOUSE;

AKR MOUSE; ANIMAL; APPETITE; ARTICLE; BLOOD; BODY COMPOSITION; CELL STRAIN HEPG2; DIET; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; HUMAN; HYPOTHALAMUS; MALE; METABOLISM; MOUSE; MOUSE MUTANT; OBESITY; PHOSPHORYLATION; WEIGHT REDUCTION;

ANIMALS; APPETITE; BODY COMPOSITION; CHOLESTANES; DIET; DISEASE MODELS, ANIMAL; HEP G2 CELLS; HUMANS; HYPOLIPIDEMIC AGENTS; HYPOTHALAMUS; INSULIN; LEPTIN; MALE; MICE; MICE, INBRED AKR; MICE, OBESE; OBESITY; PHOSPHORYLATION; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1; RECEPTOR, INSULIN; SPERMINE; STAT3 TRANSCRIPTION FACTOR; WEIGHT LOSS;

MURINAE; MUS;

EID: 77955052291     PISSN: 19307381     EISSN: 1930739X     Source Type: Journal    
DOI: 10.1038/oby.2009.444     Document Type: Article

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