Reducing Recon 2 for steady-state flux analysis of HEK cell culture

Journal of Biotechnology

Volumn 184, Issue , 2014, Pages 172-178

  Quek, Lake Ee ^a   Dietmair, Stefanie ^a   Hanscho, Michael ^b   Martínez, Verónica S ^a   Borth, Nicole ^b,c   Nielsen, Lars K ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b AUSTRIAN CENTRE OF INDUSTRIAL BIOTECHNOLOGY   (Austria)

^c UNIVERSITY OF AGRICULTURAL SCIENCES   (Austria)

Author keywords

Flux analysis; Genome scale model; Human metabolism; Mammalian cell culture; Model reduction

Indexed keywords

ENZYME ACTIVITY; GENES; METABOLISM;

FLUX ANALYSIS; GENOME-SCALE MODEL; HUMAN METABOLISMS; MAMMALIAN CELL CULTURE; MODEL REDUCTION;

CELL CULTURE;

ARTICLE; BIOLOGICAL MODEL; CELL CULTURE; CITRIC ACID CYCLE; CONTROLLED STUDY; EXTRACELLULAR SPACE; GENOME SCALE MODEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; LIPOGENESIS; METABOLIC FLUX ANALYSIS; METABOLISM; NUCLEOTIDE METABOLISM; PHENOTYPE; PHOSPHATE TRANSPORT; PRIORITY JOURNAL; PROTEIN ASSEMBLY; STEADY STATE; HEK293 CELL LINE; HUMAN GENOME; IN VITRO STUDY;

GENOME, HUMAN; HEK293 CELLS; HUMANS; IN VITRO TECHNIQUES; METABOLIC FLUX ANALYSIS; METABOLIC NETWORKS AND PATHWAYS;

EID: 84902504015     PISSN: 01681656     EISSN: 18734863     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2014.05.021     Document Type: Article

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