Activity of glutamate dehydrogenase is increased in ammonia-stressed hybridoma cells

Biotechnology and Bioengineering

Volumn 57, Issue 4, 1998, Pages 447-453

  Bonarius, Handrik P J ^a,c,d   Houtman, José H M ^d   De Gooijer, Cornelis D ^b   Tramper, Johannes ^b   Schmid, Georg ^a  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

^b WAGENINGEN UNIVERSITY   (Netherlands)

^c NOVO NORDISK A S   (Denmark)

^d ZOETIS   (United States)

Author keywords

Ammonia; Cell culture; Glutamate dehydrogenase; Mass balance; Metabolic flux

Indexed keywords

AMMONIA; ANIMAL CELL CULTURE; BIOCONVERSION; BIOSYNTHESIS; CATALYSIS; CATALYST ACTIVITY; COMPOSITION EFFECTS; METABOLISM;

GLUTAMATE DEHYDROGENASE; METABOLIC FLUX;

ENZYMES;

2 OXOGLUTARIC ACID; ALANINE AMINOTRANSFERASE; AMMONIA; ASPARTATE AMINOTRANSFERASE; GLUTAMATE DEHYDROGENASE;

ARTICLE; CELL CULTURE; CELL METABOLISM; HYBRIDOMA; KINETICS;

AMINO ACIDS; ANIMALS; CARBON; CELL DIVISION; CELL SURVIVAL; CELLS, CULTURED; GLUTAMATE DEHYDROGENASE; HYBRIDOMAS; MAMMALS; NITROGEN; QUATERNARY AMMONIUM COMPOUNDS;

ANIMALIA;

EID: 0032549164     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0290(19980220)57:4<447::AID-BIT8>3.0.CO;2-M     Document Type: Article

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