A source of the single-stranded DNA substrate for activation-induced deaminase during somatic hypermutation

Nature Communications

Volumn 5, Issue , 2014, Pages

  Wang, Xiaohua ^a   Fan, Manxia ^a   Kalis, Susan ^a   Wei, Lirong ^a   Scharff, Matthew D ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION INDUCED CYTIDINE DEAMINASE; IMMUNOGLOBULIN HEAVY CHAIN; MESSENGER RNA; RNA POLYMERASE II; SHORT HAIRPIN RNA; SINGLE STRANDED DNA; TUBULIN; AICDA (ACTIVATION-INDUCED CYTIDINE DEAMINASE); CYTIDINE DEAMINASE; IMMUNOGLOBULIN VARIABLE REGION;

DNA; IMMUNE RESPONSE; MUTATION; NUMERICAL MODEL; SUBSTRATE;

ARTICLE; BURKITT LYMPHOMA; CHROMATIN IMMUNOPRECIPITATION; EXOSOME; HUMAN; HUMAN CELL; NONSENSE MUTATION; PROMOTER REGION; SOMATIC HYPERMUTATION; TRANSCRIPTION INITIATION; TRANSCRIPTION TERMINATION; B LYMPHOCYTE; ENZYMOLOGY; GENE REARRANGEMENT; GENETICS; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOLOGY; METABOLISM; TUMOR CELL LINE;

B-LYMPHOCYTES; BURKITT LYMPHOMA; CELL LINE, TUMOR; CYTIDINE DEAMINASE; DNA, SINGLE-STRANDED; HUMANS; IMMUNOGLOBULIN CLASS SWITCHING; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN VARIABLE REGION; RNA POLYMERASE II; SOMATIC HYPERMUTATION, IMMUNOGLOBULIN;

EID: 84902493677     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms5137     Document Type: Article

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