Identification of core DNA elements that target somatic hypermutation

Journal of Immunology

Volumn 189, Issue 11, 2012, Pages 5314-5326

  Kohler, Kristin M ^a,d   McDonald, Jessica J ^a   Duke, Jamie L ^b   Arakawa, Hiroshi ^c   Tan, Sally ^a   Kleinstein, Steven H ^a,b   Buerstedde, Jean Marie ^a   Schatz, David G ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY   (United States)

^c FIRC INSTITUTE OF MOLECULAR ONCOLOGY   (Italy)

^d UNIVERSITY OF THE PACIFIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION INDUCED CYTIDINE DEAMINASE; DNA; IMMUNOGLOBULIN LIGHT CHAIN; RNA POLYMERASE II;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; CHICKEN; ENHANCER REGION; EPIGENETICS; GENE CASSETTE; GENE DELETION; GENE LOCUS; GENE SEQUENCE; GENE TARGETING; GENETIC TRANSCRIPTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REPORTER GENE; SOMATIC HYPERMUTATION;

3' FLANKING REGION; ANIMALS; B-LYMPHOCYTES; CELLS, CULTURED; CHICKENS; CHROMATIN IMMUNOPRECIPITATION; CYTIDINE DEAMINASE; DNA; ENHANCER ELEMENTS, GENETIC; GENES, IMMUNOGLOBULIN; GENETIC LOCI; IMMUNOASSAY; IMMUNOGLOBULIN VARIABLE REGION; MUTATION; PHOSPHORYLATION; RNA POLYMERASE II; SERINE; SOMATIC HYPERMUTATION, IMMUNOGLOBULIN; TRANSCRIPTION, GENETIC;

EID: 84869818088     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1202082     Document Type: Article

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