Efflux pump-mediated antibiotics resistance: Insights from computational structural biology

Interdisciplinary Sciences – Computational Life Sciences

Volumn 6, Issue 1, 2014, Pages 1-12

  Fischer, Nadine ^a,b   Raunest, Martin ^b   Schmidt, Thomas H ^b   Koch, Dennis C ^b   Kandt, Christian ^b  

^a German Research School for Simulation Sciences GmbH ^*  (Germany)

^b UNIVERSITY OF BONN   (Germany)

Author keywords

access regulation; AcrB; membrane protein; molecular dynamics simulation; multidrug transport; OprM; proton conduction; TolC

Indexed keywords

CARRIER PROTEIN; ESCHERICHIA COLI PROTEIN; OPRM PROTEIN, PSEUDOMONAS AERUGINOSA; OUTER MEMBRANE PROTEIN; PROTON; TOLC PROTEIN, E COLI;

COMPUTER PROGRAM; COMPUTER SIMULATION; CONFORMATION; DRUG EFFECT; ESCHERICHIA COLI; METABOLISM; MOLECULAR DYNAMICS; MULTIDRUG RESISTANCE; PSEUDOMONAS AERUGINOSA; REVIEW;

BACTERIAL OUTER MEMBRANE PROTEINS; COMPUTER SIMULATION; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; MEMBRANE TRANSPORT PROTEINS; MOLECULAR CONFORMATION; MOLECULAR DYNAMICS SIMULATION; PROTONS; PSEUDOMONAS AERUGINOSA; SOFTWARE;

EID: 84902288609     PISSN: 19132751     EISSN: 18671462     Source Type: Journal    
DOI: 10.1007/s12539-014-0191-3     Document Type: Article

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