Hyperglycaemia promotes human brain microvascular endothelial cell apoptosis via induction of protein kinase C-βI and prooxidant enzyme NADPH oxidase

Redox Biology

Volumn 2, Issue 1, 2014, Pages 694-701

  Shao, Beili ^a   Bayraktutan, Ulvi ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Apoptosis; Endothelial cell; Hyperglycaemia; NADPH oxidase; Protein kinase C

Indexed keywords

CASPASE 3; CASPASE 7; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN BAX; PROTEIN KINASE C ALPHA; PROTEIN KINASE C BETA; PROTEIN KINASE C BETAI; PROTEIN P22; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; UNCLASSIFIED DRUG; ISOPROTEIN; PRKCB PROTEIN, HUMAN; SMALL INTERFERING RNA; SUPEROXIDE;

APOPTOSIS; ARTICLE; ASTROCYTE; BLOOD BRAIN BARRIER; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HYPERGLYCEMIA; MICROVASCULAR ENDOTHELIAL CELL; OXIDATIVE STRESS; PERICYTE; PRIORITY JOURNAL; ANTAGONISTS AND INHIBITORS; BRAIN; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYMOLOGY; GENETICS; METABOLISM; MICROVASCULATURE; MORTALITY; PATHOLOGY; RNA INTERFERENCE;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BLOOD-BRAIN BARRIER; BRAIN; CASPASE 3; CASPASE 7; CELLS, CULTURED; ENDOTHELIAL CELLS; ENZYME ACTIVATION; HUMANS; HYPERGLYCEMIA; MICROVESSELS; NADPH OXIDASE; PROTEIN ISOFORMS; PROTEIN KINASE C BETA; RNA INTERFERENCE; RNA, SMALL INTERFERING; SUPEROXIDES; TETRADECANOYLPHORBOL ACETATE;

EID: 84901845011     PISSN: 22132317     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.redox.2014.05.005     Document Type: Article

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