Abrogation of MMP-9 gene protects against the development of retinopathy in diabetic mice by preventing mitochondrial damage

Diabetes

Volumn 60, Issue 11, 2011, Pages 3023-3033

  Kowluru, Renu A ^a   Mohammad, Ghulam ^a   Dos Santos, Julia M ^a   Zhong, Qing ^a  

^a WAYNE STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE B; GLUCOSE; HEAT SHOCK PROTEIN 60; HEAT SHOCK PROTEIN 70; MITOCHONDRIAL DNA; SMALL INTERFERING RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CAPILLARY; CELL ISOLATION; DIABETES MELLITUS; DIABETIC RETINOPATHY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME BINDING; GENE FUNCTION; GENE SILENCING; HUMAN; HUMAN TISSUE; LAMELLAR BODY; MALE; MICROVASCULATURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RETINOPATHY; ULTRASTRUCTURE;

ANIMALS; APOPTOSIS; CELLS, CULTURED; CHAPERONIN 60; DIABETIC RETINOPATHY; DNA DAMAGE; DNA, MITOCHONDRIAL; ENZYME ACTIVATION; GENE SILENCING; HSP70 HEAT-SHOCK PROTEINS; HUMANS; HYPERGLYCEMIA; MALE; MATRIX METALLOPROTEINASE 9; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MIDDLE AGED; MITOCHONDRIA; MOLECULAR TARGETED THERAPY; RETINA; RETINAL VESSELS;

EID: 80755184669     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db11-0816     Document Type: Article

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