Activation of NADPH oxidase 1 in tumour colon epithelial cells

Biochemical Journal

Volumn 415, Issue 1, 2008, Pages 57-65

  Nisimoto, Yukio ^a   Tsubouchi, Ryoto ^a   Diebold, Becky A ^b   Qiao, Shanlou ^c   Ogawas, Hisamitsu ^d   Ohara, Takuya ^e   Tamura, Minoru ^e  

^a AICHI MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c CHUBU UNIVERSITY   (Japan)

^d FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e EHIME UNIVERSITY   (Japan)

Author keywords

Caco 2 cells; Nox1; Rac1; Reactive oxygen species; Small GTPase; Superoxide

Indexed keywords

CELL MEMBRANES;

CACO-2 CELLS; NOX1; RAC1; REACTIVE OXYGEN SPECIES; SMALL GTPASE; SUPEROXIDE;

TUMORS;

DIPHENYLIODONIUM SALT; FLAVOPROTEIN; GUANOSINE DIPHOSPHATE; HEME; HYBRID PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; OXYGEN; PROTEIN INHIBITOR; PROTEIN P22; RAC1 PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; SUPEROXIDE; CATION; NOX1 PROTEIN, HUMAN; NOXA1 PROTEIN, HUMAN; NOXO1 PROTEIN, HUMAN; PHORBOL 13 ACETATE 12 MYRISTATE; RAC1 PROTEIN, HUMAN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; VESICULAR TRANSPORT ADAPTOR PROTEIN;

ARTICLE; CELL ACTIVITY; CELL FREE SYSTEM; CELL MEMBRANE; CELL STRAIN CACO 2; COLON TUMOR; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME LOCALIZATION; EPITHELIUM CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SPECTROPHOTOMETRY; CELL STRAIN HL 60; DRUG EFFECT; ENZYMOLOGY; METABOLISM; NEUTROPHIL;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; CACO-2 CELLS; CELL MEMBRANE; CELL-FREE SYSTEM; ENZYME ACTIVATION; HL-60 CELLS; HUMANS; NADPH OXIDASE; NEUTROPHILS; ONIUM COMPOUNDS; RAC1 GTP-BINDING PROTEIN; RECOMBINANT FUSION PROTEINS; SUPEROXIDES; TETRADECANOYLPHORBOL ACETATE;

EID: 53049110993     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20080300     Document Type: Article

References (45)

1. Boonstra, J. and Post, J. A. (2004) Molecular events associated with reactive oxygen species and cell cycle progression in mammalian cells. Gene 337, 1-13
2. Taniyama, T. and Griendling, K. K. (2003) Reactive oxygen species in the vasculature: molecular and cellular mechanisms. Hypertension 42, 1075-1081
3. 2-generating system modulates protein iodination and the activity of the pentose phosphate pathway in dog thyroid. Endocrinology 128, 779-785
4. Babior, B. M., Lambeth, J. D. and Nauseef, W. (2002) The neutrophil NADPH oxidase. Arch. Biochem. Biophys. 397, 342-344
5. Quinn, M. T. and Gauss, K. A. (2004) Structure and regulation of the neutrophil respiratory burst oxidase: comparison with nonphagocyte oxidase. J. Leukocyte Biol. 76, 760-781
6. 245 in a flavocytochrome containing FAD and the NADPH-binding site of the microbicidal oxidase of phagocytes. Biochem. J. 284, 781-788
7. Baker, M. A. and Aitken, R. J. (2004) The importance of redox regulated pathways in sperm cell biology. Mol. Cell. Endocrinol. 216, 47-54
8. Key, L. L., Wolf. W. C., Gundberg, C. M. and Ries, W. L. (1994) Superoxide and bone resorption. Bone 15, 431-436
9. Banfi, B., Clark, R. A., Steger, K. and Krause, K. H. (2003) Two novel proteins activate superoxide generation by the NADPH oxidase NOX1. J. Biol. Chem. 278, 3510-3513
10. Cheng, G. and Lambeth, J. D. (2004) NOX01, regulation of lipid binding, localization, and activation of Nox1 by the Phox homology (PX) domain. J. Biol. Chem. 279, 4737-4742
11. phox support superoxide production by NAD(P)H oxidase 1 in colon elpithelial cells. J. Biol. Chem. 27B, 20006-20012
12. Kawahara, T., Teshima, S., Oka, A., Sugiyama, T., Kishi, K. and Rokutan, K. (2001) Type 1 Helicobacter pylori lipopolysaccharide stimulates Toll-like receptor 4 and activates mitogen oxidase 1 in gastric pit cells. Infect. Immun. 69, 4382-4389
13. Kawahara, T., Kuwano, Y., Teshima-Kondo, S., Takeya, R., Sumimoto, H., Kishi, K., Tsunawaki, S., Hirayama, T. and Rokutan, K. (2004) Role of nicotinamide adenine dinucleotide phosphate oxidase 1 in oxidative burst response to toll-like receptor 5 signaling in large intestinal epithelial cells. J. Immunol. 172, 3051-3058
14. phox participate in activation of superoxide-producing NADPH oxidase. J. Biol. Chem. 278, 25234-25246
15. phox: cloning and tissue expression of Nox3, Nox4 and Nox5. Gene 269, 131-140
16. Griendling, K. K., Sorescu, D. and Ushio-Fukai, M. (2000) NAD(P)H oxidase: role in cardiovascular biology and disease. Circ. Res. 86, 494-501
17. Doi, H., Kugiyama, K., Oka, H., Sugiyama, S., Ogata, N., Koide, S., Nakamura, S. and Yasue, H. (2000) Remnant lipoproteins induce proatherothromogenic molecules in endothelial cells through a redox-sensitive mechanism. Circulation 102, 670-676
18. Kawakami, A., Tanaka, A., Chiba, T., Nakajima, K., Shimokado, K. and Yoshida, M. (2003) Remnant lipoprotein-induced smooth muscle cell proliferation involves epidermal growth factor receptor transactivation. Circulation 108, 2679-2688
19. Shin, H. K., Kim, Y. K., Kim, K. Y., Lee, J. H. and Hong, K. W. (2004) Remnant lipoprotein particles induce apoptosis in endothelial cells by NAD(P)H oxidase: Mediated production of superoxide and cytolkines via lectin-like oxidized low density lipoprotein receptor-1 activation. Circulation 109, 1022-1028
20. Byrne, J. A., Grieve, D. J., Bendall, J. K., Li, J. M., Gove, C., Lambeth, J. D., Cave, A. C. and Shah, A. M. (2003) Contrasting roles of NADPH oxidase isoforms in pressure-overload versus angiotensin II-induced cardiac hypertrophy. Circ. Res. 93, 802-804
21. Liu, J.. Ormsby, A., Oja-Tebbe, N. and Pagano. P. J. (2004) Gene transfer of NAD(P)H oxidase inhibitor to the vascular adventitia attenuates medial smooth muscle hypertrophy. Circ. Res. 95, 587-594
22. phox in endothelial cell superoxide production in response to phorbol ester and tumor necrosis factor-α. Circ. Res. 90, 143-150
23. Mark, K. S., Trickler, W. J. and Miller, D. W. (2001) Tumor necrosis factor-α induces cyclooxygenase-2 expression and prostaglandin release in brain microvessel endothelial cells. J. Pharmacol. Exp. Ther. 297, 1051-1058
24. - generating oxidase of neutrophils by an azido derivative of FAD. Biochemistry 34, 1760-1770
25. phox is the heme binding subunit of the superoxide-generating NADPH oxidase. Proc. Natl. Acad. Sci. U.S.A. 95, 7993-7998
26. 558: the flavin-binding component of the phagocyte NADPH oxidase. Science 256, 1459-1462
27. 558, a component of the phagocyte NADPH oxidase, is a flavoprotein. Biochem. Biophys. Res. Commun. 186, 1368-1375
28. phox (1-210) and Rac complex. Biochemistry 43, 9567-9575
29. phox and regulation of phagocytic NADPH oxidase activity. Science 265, 531-533
30. Cheng, G., Diebold, B., Hughes. Y. and Lambeth, J. D. (2006) Nox1-dependent reactive oxygen generation is regulated by Rac1. J. Biol. Chem. 281, 17718-17726
31. Nisimoto, Y., Otsuka-Murakami, H. and Iwata, S. (1994) NADPH-cytochrome c reductase from human neutrophil membranes: purification, characterization and localization. Biochem. J. 297, 585-593
32. Tauber, A. J. and Goetzl, E. J. (1979) Structural and catalytic properties of the solubilized superoxide-generating activity of polymorphonuclear leukocytes. Solubilization, stabilization in solution, and partial characterization. Biochemistry 18, 5576-5584
33. Light, D. R., Walsh, C., O'Callaghan, A. M., Goezl, E. J. and Tauber, A. I. (1981) Characteristics of the cofactor requirements for the superoxide-generating NADPH oxidase of human polymorphonuclear leukocytes. Biochemistry 20, 1468-1476
34. Faeder, E. J. and Siegel, L. M. (1973) A rapid micromethod for determination of FMN and FAD in mixtures. Anal. Biochem. 53, 332-336
35. phox (1-210) reconstitutes NADPH oxicase with higher activity and stability than the individual components. Biochemistry 40, 14089-14097
36. phox in complex with Rac-GTP. Mol. Cell 6, 899-907
37. Hua, J., Hasebe, T., Someya, A., Nakamura, S., Sugimoto, K. and Nagaoka, I. (2000) Evaluation of the expression of NADPH oxidase components during maturation of HL-60 cells to neutrophil lineage. J. Leukoc. Biol. 68, 216-224
38. Levy, R., Rotrosen, D., Nagauker, O., Leto, T. L. and Malech, H. L. (1990) Induction of the respiratory burst in HL-60 cells: correlation of function and protein expression. J. Immunol. 145, 2595-2601
39. Arnold, R. S., Shi, J., Murad, E., Whalen, A. M., Sun, C. Q., Polavarapu, R., Pardthsarathy, S., Petros, J. A. and Lambeth, J. D. (2001) Hydrogen peroxide mediates the cell growth and transformation caused by the mitogenic oxidase Nox1. Proc. Natl. Acad. Sci. U.S.A. 98, 5550-5555
40. Shiose, A., Kuroda, J., Tsuruya, K., Hirai, M., Hirakata, H., Naito, S., Hattori, M., Sakai, Y. and Sumimoto, H. (2001) A novel superoxide-producing NAD(P)H oxidase in kidney. J. Biol. Chem. 276, 1417-1423
41. Miyano, K., Ueno, N., Tkakeya, R. and Sumimoto, H. (2006) Direct involvement of the small GTPase Rac in the activation of the superoxide-producing NADPH oxidase Nox1. J. Biol. Chem. 281, 21857-21868
42. Ueyama, T., Geiszt, M. and Leto, T. L. (2006) Involvement of Rac1 in activation of multicomponent Nox1- and Nox3-based NADPH oxidase. Mol. Cell. Biol. 26, 2160-2174
43. phox in the regulated production of superoxide by phagocytes. J. Immunol. 170, 299-306
44. Fan, C. Y., Katsuyama, M. and Yabe-Nishimura, C. (2005) PKCδ mediates up-regulation of NOX1, a catalytic subunit of NADPH oxidase, via transactivation of the EGF receptor: possible involvement of PKCδ in vascular hypertrophy. Biochem. J. 390, 761-767
45. Kim, J.-S., Diebold, B. A., Babior, B. M., Knaus, U. G. and Bokoch, G. M. (2007) Regulation of Nox1 activity via protein kinase A-mediated phosphorylation of NoxA1 and 14-3-3 binding. J. Biol. Chem. 282, 34787-34800