Inhibition of protein kinase Cβ reverses increased blood-brain barrier permeability during hyperglycemic stroke and prevents edema formation in vivo

Stroke

Volumn 42, Issue 11, 2011, Pages 3252-3257

  Cipolla, Marilyn J ^a   Huang, Quillan ^a   Sweet, Julie G ^a  

^a UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

Author keywords

blood brain barrier; hyperglycemia; protein kinase C; reperfusion injury; vasogenic edema

Indexed keywords

4,5 BIS(4 FLUOROANILINO)PHTHALIMIDE; CPG 53353; GLUCOSE; PROTEIN KINASE C BETA; PROTEIN KINASE C BETA INHIBITOR; STREPTOZOCIN; UNCLASSIFIED DRUG; WATER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD BRAIN BARRIER; BRAIN EDEMA; CONTROLLED STUDY; ENZYME INHIBITION; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; HYPERGLYCEMIC STROKE; IN VIVO STUDY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; PRIORITY JOURNAL; RAT; STREPTOZOCIN DIABETES; STROKE; WATER CONTENT; WISTAR RAT;

ANIMALS; BLOOD-BRAIN BARRIER; BRAIN EDEMA; CAPILLARY PERMEABILITY; HYPERGLYCEMIA; MALE; PHTHALIMIDES; PROTEIN KINASE C; PROTEIN KINASE INHIBITORS; RATS; RATS, WISTAR; STROKE;

EID: 80054994277     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.111.623991     Document Type: Article

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