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Volumn 2, Issue 6, 2013, Pages 635-646

Altered biometal homeostasis is associated with CLN6 mRNA loss in mouse neuronal ceroid lipofuscinosis

Author keywords

Biometal homeostasis; CLN6; Metal transporter; Neurodegeneration; Neuronal ceroid lipofuscinoses

Indexed keywords


EID: 84965071002     PISSN: None     EISSN: 20466390     Source Type: Journal    
DOI: 10.1242/bio.20134804     Document Type: Article
Times cited : (26)

References (48)
  • 1
    • 84856731679 scopus 로고    scopus 로고
    • The human ZIP4 transporter has two distinct binding affinities and mediates transport of multiple transition metals
    • Antala, S. and Dempski, R. E. (2012). The human ZIP4 transporter has two distinct binding affinities and mediates transport of multiple transition metals. Biochemistry 51, 963-973.
    • (2012) Biochemistry , vol.51 , pp. 963-973
    • Antala, S.1    Dempski, R.E.2
  • 4
    • 72949104344 scopus 로고    scopus 로고
    • Metal ion physiopathology in neurodegenerative disorders
    • Bolognin, S., Messori, L. and Zatta, P. (2009). Metal ion physiopathology in neurodegenerative disorders. Neuromolecular Med. 11, 223-238.
    • (2009) Neuromolecular Med. , vol.11 , pp. 223-238
    • Bolognin, S.1    Messori, L.2    Zatta, P.3
  • 5
    • 84861723960 scopus 로고    scopus 로고
    • Mutation of the parkinsonism gene ATP13A2 causes neuronal ceroid-lipofuscinosis
    • Bras, J., Verloes, A., Schneider, S. A., Mole, S. E. and Guerreiro, R. J. (2012). Mutation of the parkinsonism gene ATP13A2 causes neuronal ceroid-lipofuscinosis. Hum. Mol. Genet. 21, 2646-2650.
    • (2012) Hum. Mol. Genet. , vol.21 , pp. 2646-2650
    • Bras, J.1    Verloes, A.2    Schneider, S.A.3    Mole, S.E.4    Guerreiro, R.J.5
  • 6
    • 0032557726 scopus 로고    scopus 로고
    • Neuronal ceroid lipofuscinosis (nclf), a new disorder of the mouse linked to chromosome 9
    • Bronson, R. T., Donahue, L. R., Johnson, K. R., Tanner, A., Lane, P. W. and Faust, J. R. (1998). Neuronal ceroid lipofuscinosis (nclf), a new disorder of the mouse linked to chromosome 9. Am. J. Med. Genet. 77, 289-297.
    • (1998) Am. J. Med. Genet. , vol.77 , pp. 289-297
    • Bronson, R.T.1    Donahue, L.R.2    Johnson, K.R.3    Tanner, A.4    Lane, P.W.5    Faust, J.R.6
  • 7
    • 84860834511 scopus 로고    scopus 로고
    • Longitudinal analysis of the behavioural phenotype in hdh(CAG)150 Huntington's disease knock-in mice
    • Brooks, S., Higgs, G., Jones, L. and Dunnett, S. B. (2012). Longitudinal analysis of the behavioural phenotype in Hdh(CAG)150 Huntington's disease knock-in mice. Brain Res. Bull. 88, 182-188.
    • (2012) Brain Res. Bull. , vol.88 , pp. 182-188
    • Brooks, S.1    Higgs, G.2    Jones, L.3    Dunnett, S.B.4
  • 8
    • 79951993462 scopus 로고    scopus 로고
    • Distinct early molecular responses to mutations causing vLINCL and JNCL presage ATP synthase subunit C accumulation in cerebellar cells
    • Cao, Y., Staropoli, J. F., Biswas, S., Espinola, J. A., MacDonald, M. E., Lee, J. M. and Cotman, S. L. (2011). Distinct early molecular responses to mutations causing vLINCL and JNCL presage ATP synthase subunit C accumulation in cerebellar cells. PLoS ONE 6, e17118.
    • (2011) PLoS ONE , vol.6 , pp. e17118
    • Cao, Y.1    Staropoli, J.F.2    Biswas, S.3    Espinola, J.A.4    MacDonald, M.E.5    Lee, J.M.6    Cotman, S.L.7
  • 9
    • 84861924529 scopus 로고    scopus 로고
    • Improvement of cerebellum redox states and cholinergic functions contribute to the beneficial effects of silymarin against manganese-induced neurotoxicity
    • Chtourou, Y., Fetoui, H., Garoui, E. M., Boudawara, T. and Zeghal, N. (2012). Improvement of cerebellum redox states and cholinergic functions contribute to the beneficial effects of silymarin against manganese-induced neurotoxicity. Neurochem. Res. 37, 469-479.
    • (2012) Neurochem. Res. , vol.37 , pp. 469-479
    • Chtourou, Y.1    Fetoui, H.2    Garoui, E.M.3    Boudawara, T.4    Zeghal, N.5
  • 10
    • 0242551370 scopus 로고    scopus 로고
    • Chronic activation of ERK and neurodegenerative diseases
    • Colucci-D'Amato, L., Perrone-Capano, C. and di Porzio, U. (2003). Chronic activation of ERK and neurodegenerative diseases. Bioessays 25, 1085-1095.
    • (2003) Bioessays , vol.25 , pp. 1085-1095
    • Colucci-D'Amato, L.1    Perrone-Capano, C.2    Di Porzio, U.3
  • 11
    • 84867146865 scopus 로고    scopus 로고
    • The cation selectivity of the ZIP transporters
    • Dempski, R. E. (2012). The cation selectivity of the ZIP transporters. Curr Top Membr 69, 221-245.
    • (2012) Curr Top Membr , vol.69 , pp. 221-245
    • Dempski, R.E.1
  • 14
    • 48849084889 scopus 로고    scopus 로고
    • A murine model of infantile neuronal ceroid lipofuscinosis-ultrastructural evaluation of storage in the central nervous system and viscera
    • Galvin, N., Vogler, C., Levy, B., Kovacs, A., Griffey, M. and Sands, M. S. (2008). A murine model of infantile neuronal ceroid lipofuscinosis-ultrastructural evaluation of storage in the central nervous system and viscera. Pediatr. Dev. Pathol. 11, 185-192.
    • (2008) Pediatr. Dev. Pathol. , vol.11 , pp. 185-192
    • Galvin, N.1    Vogler, C.2    Levy, B.3    Kovacs, A.4    Griffey, M.5    Sands, M.S.6
  • 16
    • 77953837000 scopus 로고    scopus 로고
    • ERK signaling leads to mitochondrial dysfunction in extracellular zinc-induced neurotoxicity
    • He, K. and Aizenman, E. (2010). ERK signaling leads to mitochondrial dysfunction in extracellular zinc-induced neurotoxicity. J. Neurochem. 114, 452-461.
    • (2010) J. Neurochem. , vol.114 , pp. 452-461
    • He, K.1    Aizenman, E.2
  • 17
    • 83655192207 scopus 로고    scopus 로고
    • Unilateral nigrostriatal 6-hydroxydopamine lesions in mice I: Motor impairments identify extent of dopamine depletion at three different lesion sites
    • Heuer, A., Smith, G. A., Lelos, M. J., Lane, E. L. and Dunnett, S. B. (2012). Unilateral nigrostriatal 6-hydroxydopamine lesions in mice I: motor impairments identify extent of dopamine depletion at three different lesion sites. Behav. Brain Res. 228, 30-43.
    • (2012) Behav. Brain Res. , vol.228 , pp. 30-43
    • Heuer, A.1    Smith, G.A.2    Lelos, M.J.3    Lane, E.L.4    Dunnett, S.B.5
  • 18
    • 17644400171 scopus 로고    scopus 로고
    • The ZIP7 gene (Slc39a7) encodes a zinc transporter involved in zinc homeostasis of the golgi apparatus
    • Huang, L., Kirschke, C. P., Zhang, Y. and Yu, Y. Y. (2005). The ZIP7 gene (Slc39a7) encodes a zinc transporter involved in zinc homeostasis of the Golgi apparatus. J. Biol. Chem. 280, 15456-15463.
    • (2005) J. Biol. Chem. , vol.280 , pp. 15456-15463
    • Huang, L.1    Kirschke, C.P.2    Zhang, Y.3    Yu, Y.Y.4
  • 19
    • 62949195147 scopus 로고    scopus 로고
    • Neuronal ceroid lipofuscinoses
    • Jalanko, A. and Braulke, T. (2009). Neuronal ceroid lipofuscinoses. Biochim. Biophys. Acta 1793, 697-709.
    • (2009) Biochim. Biophys. Acta , vol.1793 , pp. 697-709
    • Jalanko, A.1    Braulke, T.2
  • 20
    • 77952291042 scopus 로고    scopus 로고
    • Genome-wide microarray analysis of brain gene expression in mice on a short-term high iron diet
    • Johnstone, D. and Milward, E. A. (2010). Genome-wide microarray analysis of brain gene expression in mice on a short-term high iron diet. Neurochem. Int. 56, 856-863.
    • (2010) Neurochem. Int. , vol.56 , pp. 856-863
    • Johnstone, D.1    Milward, E.A.2
  • 21
    • 84875032283 scopus 로고    scopus 로고
    • Increased zinc and manganese in parallel with neurodegeneration, synaptic protein changes and activation of akt/GSK3 signaling in ovine CLN6 neuronal ceroid lipofuscinosis
    • Kanninen, K. M., Grubman, A., Meyerowitz, J., Duncan, C., Tan, J. L., Parker, S. J., Crouch, P. J., Paterson, B. M., Hickey, J. L., Donnelly, P. S. et al. (2013). Increased zinc and manganese in parallel with neurodegeneration, synaptic protein changes and activation of Akt/GSK3 signaling in ovine CLN6 neuronal ceroid lipofuscinosis. PLoS ONE 8, e58644.
    • (2013) PLoS ONE , vol.8 , pp. e58644
    • Kanninen, K.M.1    Grubman, A.2    Meyerowitz, J.3    Duncan, C.4    Tan, J.L.5    Parker, S.J.6    Crouch, P.J.7    Paterson, B.M.8    Hickey, J.L.9    Donnelly, P.S.10
  • 23
    • 84857676339 scopus 로고    scopus 로고
    • Update of the mutation spectrum and clinical correlations of over 360 mutations in eight genes that underlie the neuronal ceroid lipofuscinoses
    • Kousi, M., Lehesjoki, A. E. and Mole, S. E. (2012). Update of the mutation spectrum and clinical correlations of over 360 mutations in eight genes that underlie the neuronal ceroid lipofuscinoses. Hum. Mutat. 33, 42-63.
    • (2012) Hum. Mutat. , vol.33 , pp. 42-63
    • Kousi, M.1    Lehesjoki, A.E.2    Mole, S.E.3
  • 24
    • 27744545492 scopus 로고    scopus 로고
    • Alterations in zinc transporter protein-1 (ZnT-1) in the brain of subjects with mild cognitive impairment, early, and late-stage Alzheimer's disease
    • Lovell, M. A., Smith, J. L., Xiong, S. and Markesbery, W. R. (2005). Alterations in zinc transporter protein-1 (ZnT-1) in the brain of subjects with mild cognitive impairment, early, and late-stage Alzheimer's disease. Neurotox. Res. 7, 265-271.
    • (2005) Neurotox. Res. , vol.7 , pp. 265-271
    • Lovell, M.A.1    Smith, J.L.2    Xiong, S.3    Markesbery, W.R.4
  • 25
    • 75949120131 scopus 로고    scopus 로고
    • Alterations of zinc transporter proteins ZnT-1, ZnT-4 and ZnT-6 in preclinical Alzheimer's disease brain
    • Lyubartseva, G., Smith, J. L., Markesbery, W. R. and Lovell, M. A. (2010). Alterations of zinc transporter proteins ZnT-1, ZnT-4 and ZnT-6 in preclinical Alzheimer's disease brain. Brain Pathol. 20, 343-350.
    • (2010) Brain Pathol. , vol.20 , pp. 343-350
    • Lyubartseva, G.1    Smith, J.L.2    Markesbery, W.R.3    Lovell, M.A.4
  • 26
    • 64549084081 scopus 로고    scopus 로고
    • Cerebellar pathology and motor deficits in the palmitoyl protein thioesterase 1-deficient mouse
    • Macauley, S. L., Wozniak, D. F., Kielar, C., Tan, Y., Cooper, J. D. and Sands, M. S. (2009). Cerebellar pathology and motor deficits in the palmitoyl protein thioesterase 1-deficient mouse. Exp. Neurol. 217, 124-135.
    • (2009) Exp. Neurol. , vol.217 , pp. 124-135
    • Macauley, S.L.1    Wozniak, D.F.2    Kielar, C.3    Tan, Y.4    Cooper, J.D.5    Sands, M.S.6
  • 28
    • 84861419337 scopus 로고    scopus 로고
    • Mn(II) and Zn(II) interactions with peptide fragments from Parkinson's disease genes
    • Medici, S., Peana, M., Delogu, L. G. and Zoroddu, M. A. (2012). Mn(II) and Zn(II) interactions with peptide fragments from Parkinson's disease genes. Dalton Trans. 41, 4378-4388.
    • (2012) Dalton Trans. , vol.41 , pp. 4378-4388
    • Medici, S.1    Peana, M.2    Delogu, L.G.3    Zoroddu, M.A.4
  • 29
    • 8444239335 scopus 로고    scopus 로고
    • Behavioral characterization in a comprehensive mouse test battery reveals motor and sensory impairments in growth-associated protein-43 null mutant mice
    • Metz, G. A. and Schwab, M. E. (2004). Behavioral characterization in a comprehensive mouse test battery reveals motor and sensory impairments in growth-associated protein-43 null mutant mice. Neuroscience 129, 563-574.
    • (2004) Neuroscience , vol.129 , pp. 563-574
    • Metz, G.A.1    Schwab, M.E.2
  • 30
    • 0021276999 scopus 로고
    • Cardiac involvement in juvenile ceroid lipofuscinosis of the spielmeyer-vogt-sjögren type: Prospective noninvasive findings in two siblings
    • Michielsen, P., Martin, J. J., Vanagt, E., Vrints, C., Gillebert, T. and Snoeck, J. (1984). Cardiac involvement in juvenile ceroid lipofuscinosis of the Spielmeyer-Vogt-Sjögren type: prospective noninvasive findings in two siblings. Eur. Neurol. 23, 166-172.
    • (1984) Eur. Neurol. , vol.23 , pp. 166-172
    • Michielsen, P.1    Martin, J.J.2    Vanagt, E.3    Vrints, C.4    Gillebert, T.5    Snoeck, J.6
  • 31
    • 33846028706 scopus 로고    scopus 로고
    • Zinc induces cell death in immortalized embryonic hippocampal cells via activation of akt-GSK-3beta signaling
    • Min, Y. K., Lee, J. E. and Chung, K. C. (2007). Zinc induces cell death in immortalized embryonic hippocampal cells via activation of Akt-GSK-3beta signaling. Exp. Cell Res. 313, 312-321.
    • (2007) Exp. Cell Res. , vol.313 , pp. 312-321
    • Min, Y.K.1    Lee, J.E.2    Chung, K.C.3
  • 32
    • 3242712107 scopus 로고    scopus 로고
    • CLN6, which is associated with a lysosomal storage disease, is an endoplasmic reticulum protein
    • Mole, S. E., Michaux, G., Codlin, S., Wheeler, R. B., Sharp, J. D. and Cutler, D. F. (2004). CLN6, which is associated with a lysosomal storage disease, is an endoplasmic reticulum protein. Exp. Cell Res. 298, 399-406.
    • (2004) Exp. Cell Res. , vol.298 , pp. 399-406
    • Mole, S.E.1    Michaux, G.2    Codlin, S.3    Wheeler, R.B.4    Sharp, J.D.5    Cutler, D.F.6
  • 33
    • 84861214679 scopus 로고    scopus 로고
    • Effect of dietary iron deficiency and overload on the expression of ZIP metal-ion transporters in rat liver
    • Nam, H. and Knutson, M. D. (2012). Effect of dietary iron deficiency and overload on the expression of ZIP metal-ion transporters in rat liver. Biometals 25, 115-124.
    • (2012) Biometals , vol.25 , pp. 115-124
    • Nam, H.1    Knutson, M.D.2
  • 34
    • 79954623288 scopus 로고    scopus 로고
    • Cardiac involvement in juvenile neuronal ceroid lipofuscinosis (Batten disease)
    • Ostergaard, J. R., Rasmussen, T. B. and Mølgaard, H. (2011). Cardiac involvement in juvenile neuronal ceroid lipofuscinosis (Batten disease). Neurology 76, 1245-1251.
    • (2011) Neurology , vol.76 , pp. 1245-1251
    • Ostergaard, J.R.1    Rasmussen, T.B.2    Mølgaard, H.3
  • 36
    • 80053340219 scopus 로고    scopus 로고
    • Mechanisms controlling the cellular accumulation of copper bis(thiosemicarbazonato) complexes
    • Price, K. A., Crouch, P. J., Volitakis, I., Paterson, B. M., Lim, S., Donnelly, P. S. and White, A. R. (2011). Mechanisms controlling the cellular accumulation of copper bis(thiosemicarbazonato) complexes. Inorg. Chem. 50, 9594-9605.
    • (2011) Inorg. Chem. , vol.50 , pp. 9594-9605
    • Price, K.A.1    Crouch, P.J.2    Volitakis, I.3    Paterson, B.M.4    Lim, S.5    Donnelly, P.S.6    White, A.R.7
  • 39
    • 34548484857 scopus 로고    scopus 로고
    • Mechanism and regulation of cellular zinc transport
    • Sekler, I., Sensi, S. L., Hershfinkel, M. and Silverman, W. F. (2007). Mechanism and regulation of cellular zinc transport. Mol. Med. 13, 337-343.
    • (2007) Mol. Med. , vol.13 , pp. 337-343
    • Sekler, I.1    Sensi, S.L.2    Hershfinkel, M.3    Silverman, W.F.4
  • 41
    • 5644241723 scopus 로고    scopus 로고
    • A mouse model of classical late-infantile neuronal ceroid lipofuscinosis based on targeted disruption of the CLN2 gene results in a loss of tripeptidyl-peptidase I activity and progressive neurodegeneration
    • Sleat, D. E., Wiseman, J. A., El-Banna, M., Kim, K. H., Mao, Q., Price, S., Macauley, S. L., Sidman, R. L., Shen, M. M., Zhao, Q. et al. (2004). A mouse model of classical late-infantile neuronal ceroid lipofuscinosis based on targeted disruption of the CLN2 gene results in a loss of tripeptidyl-peptidase I activity and progressive neurodegeneration. J. Neurosci. 24, 9117-9126.
    • (2004) J. Neurosci. , vol.24 , pp. 9117-9126
    • Sleat, D.E.1    Wiseman, J.A.2    El-Banna, M.3    Kim, K.H.4    Mao, Q.5    Price, S.6    Macauley, S.L.7    Sidman, R.L.8    Shen, M.M.9    Zhao, Q.10
  • 42
    • 0029422305 scopus 로고
    • Antiarrhythmic action of pharmacological administration of magnesium in heart failure: A critical review of new data
    • Sueta, C. A., Patterson, J. H. and Adams, K. F., Jr. (1995). Antiarrhythmic action of pharmacological administration of magnesium in heart failure: a critical review of new data. Magnes. Res. 8, 389-401.
    • (1995) Magnes. Res. , vol.8 , pp. 389-401
    • Sueta, C.A.1    Patterson, J.H.2    Adams, K.F.3
  • 43
    • 1642494591 scopus 로고    scopus 로고
    • Structurefunction analysis of HKE4, a member of the new LIV-1 subfamily of zinc transporters
    • Taylor, K. M., Morgan, H. E., Johnson, A. and Nicholson, R. I. (2004). Structurefunction analysis of HKE4, a member of the new LIV-1 subfamily of zinc transporters. Biochem. J. 377, 131-139.
    • (2004) Biochem. J. , vol.377 , pp. 131-139
    • Taylor, K.M.1    Morgan, H.E.2    Johnson, A.3    Nicholson, R.I.4
  • 44
    • 84855870087 scopus 로고    scopus 로고
    • High expression of disease-related cln6 in the cerebral cortex, purkinje cells, dentate gyrus, and hippocampal ca1 neurons
    • Thelen, M., Fehr, S., Schweizer, M., Braulke, T. and Galliciotti, G. (2012a). High expression of disease-related Cln6 in the cerebral cortex, purkinje cells, dentate gyrus, and hippocampal ca1 neurons. J. Neurosci. Res. 90, 568-574.
    • (2012) J. Neurosci. Res. , vol.90 , pp. 568-574
    • Thelen, M.1    Fehr, S.2    Schweizer, M.3    Braulke, T.4    Galliciotti, G.5
  • 45
    • 84859952517 scopus 로고    scopus 로고
    • Disruption of the autophagy-lysosome pathway is involved in neuropathology of the nclf mouse model of neuronal ceroid lipofuscinosis
    • Thelen, M., Damme, M., Schweizer, M., Hagel, C., Wong, A. M., Cooper, J. D., Braulke, T. and Galliciotti, G. (2012b). Disruption of the autophagy-lysosome pathway is involved in neuropathology of the nclf mouse model of neuronal ceroid lipofuscinosis. PLoS ONE 7, e35493.
    • (2012) PLoS ONE , vol.7 , pp. e35493
    • Thelen, M.1    Damme, M.2    Schweizer, M.3    Hagel, C.4    Wong, A.M.5    Cooper, J.D.6    Braulke, T.7    Galliciotti, G.8
  • 47
    • 84867249792 scopus 로고    scopus 로고
    • ZIP8 is an iron and zinc transporter whose cell-surface expression is up-regulated by cellular iron loading
    • Wang, C. Y., Jenkitkasemwong, S., Duarte, S., Sparkman, B. K., Shawki, A., Mackenzie, B. and Knutson, M. D. (2012). ZIP8 is an iron and zinc transporter whose cell-surface expression is up-regulated by cellular iron loading. J. Biol. Chem. 287, 34032-34043.
    • (2012) J. Biol. Chem. , vol.287 , pp. 34032-34043
    • Wang, C.Y.1    Jenkitkasemwong, S.2    Duarte, S.3    Sparkman, B.K.4    Shawki, A.5    Mackenzie, B.6    Knutson, M.D.7


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