Increased gene dosage plays a predominant role in the initial stages of evolution of duplicate tem-1 beta lactamase genes

Evolution

Volumn 68, Issue 6, 2014, Pages 1775-1791

  Dhar, Riddhiman ^a,b,c   Bergmiller, Tobias ^d,e   Wagner, Andreas ^a,b,f  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

^c CENTRE FOR GENOMIC REGULATION CRG   (Spain)

^d ETH ZURICH   (Switzerland)

^e INSTITUTE OF SCIENCE AND TECHNOLOGY AUSTRIA   (Austria)

^f SANTA FE INSTITUTE   (Mexico)

Author keywords

Beta lactamase; Duplicate genes; Experimental evolution; Gene dosage

Indexed keywords

COLIFORM BACTERIUM; EVOLUTIONARY BIOLOGY; EXPERIMENTAL STUDY; FUNCTIONAL ROLE; GENE EXPRESSION; GENOMICS; MUTATION;

ESCHERICHIA COLI;

ANTIINFECTIVE AGENT; BETA LACTAMASE; ESCHERICHIA COLI PROTEIN;

DRUG EFFECTS; ENVIRONMENT; ESCHERICHIA COLI; GENE DOSAGE; GENE DUPLICATION; GENETIC SELECTION; GENETICS; MOLECULAR EVOLUTION; POINT MUTATION;

ANTI-BACTERIAL AGENTS; BETA-LACTAMASES; ENVIRONMENT; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; EVOLUTION, MOLECULAR; GENE DOSAGE; GENE DUPLICATION; POINT MUTATION; SELECTION, GENETIC;

EID: 84901697309     PISSN: 00143820     EISSN: 15585646     Source Type: Journal    
DOI: 10.1111/evo.12373     Document Type: Article

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