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Volumn 41, Issue 6, 2014, Pages 463-475

Abandon the mouse research ship? Not just yet!

(27)  Osuchowski, Marcin F a   Remick, Daniel G b   Lederer, James A c   Lang, Charles H d   Aasen, Ansgar O e   Aibiki, Mayuki f   Azevedo, Luciano C g   Bahrami, Soheyl a   Boros, Mihaly h   Cooney, Robert i   Cuzzocrea, Salvatore j   Jiang, Yong k   Junger, Wolfgang G l   Hirasawa, Hiroyuki m   Hotchkiss, Richard S n   Li, Xiang An o   Radermacher, Peter p   Redl, Heinz a   Salomao, Reinaldo q   Soebandrio, Amin r   more..


Author keywords

burn; endotoxemia; Mouse models of critical illness; sepsis; trauma

Indexed keywords

ENDOTOXIN; GELATINASE A; GELATINASE B; INTERLEUKIN 1; INTERLEUKIN 1BETA; INTERLEUKIN 6; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

EID: 84901626481     PISSN: 10732322     EISSN: 15400514     Source Type: Journal    
DOI: 10.1097/SHK.0000000000000153     Document Type: Review
Times cited : (131)

References (196)
  • 1
    • 84901613626 scopus 로고
    • US Congress Office of Technology Assessment 25 2013 Washington, D.C. US Government Printing Office; February OTA-BA-273 Available at. Accessed October
    • US Congress, Office of Technology Assessment. Alternatives to Animal Use in Research, Testing, and Education. Washington, DC: US Government Printing Office; February 1986. OTA-BA-273. Available at: Http://govinfo. library.unt.edu/ota/Ota-3/DATA/1986/8601. Accessed October 25, 2013
    • (1986) Alternatives to Animal Use in Research, Testing and Education
  • 4
    • 84868308087 scopus 로고    scopus 로고
    • Model organisms: Theres more to life than rats and flies
    • Bolker J: Model organisms: Theres more to life than rats and flies. Nature 491(7422):31-33, 2012
    • (2012) Nature , vol.491 , Issue.7422 , pp. 31-33
    • Bolker, J.1
  • 5
    • 80053898650 scopus 로고    scopus 로고
    • Of mice and men: Experimental autoimmune encephalitis and multiple sclerosis
    • Handel AE, Lincoln MR, Ramagopalan SV: Of mice and men: Experimental autoimmune encephalitis and multiple sclerosis. Eur J Clin Invest 41(11): 1254-1258, 2011
    • (2011) Eur J Clin Invest , vol.41 , Issue.11 , pp. 1254-1258
    • Handel, A.E.1    Lincoln, M.R.2    Ramagopalan, S.V.3
  • 6
    • 1342303482 scopus 로고    scopus 로고
    • Of mice and not men: Differences between mouse and human immunology
    • Mestas J, Hughes CC: Of mice and not men: Differences between mouse and human immunology. J Immunol 172(5):2731-2738, 2004
    • (2004) J Immunol , vol.172 , Issue.5 , pp. 2731-2738
    • Mestas, J.1    Hughes, C.C.2
  • 7
    • 84887607714 scopus 로고    scopus 로고
    • February 12, 2013 (nytimes.com Available at Accessed October 25 2013
    • Kolata G: Mice Fall Short as Test Subjects for Humans Deadly Ills. February 12, 2013 (nytimes.com): Available at: Http://www.nytimes.com/2013/02/ 12/ science/testing-of-some-deadly-diseases-on-mice-mislead-reportsays. html?pagewanted=1&-r=3&ref=global-home&comments. Accessed October 25, 2013
    • Mice Fall Short as Test Subjects for Humans Deadly Ills
    • Kolata, G.1
  • 8
    • 84901613627 scopus 로고    scopus 로고
    • February 12 Available at Accessed October 25 2013
    • In science.slashdot.org. February 12, 2013. Available at: Http://science. slashdot.org/story/13/02/12/1823238/drug-testing-in-mice-may-be-a-wasteof- time-researchers-warn. Accessed October 25, 2013
    • (2013) Science.Slashdot.Org
  • 9
    • 84901644506 scopus 로고    scopus 로고
    • February 14, 2013 (Huffingtonpost.com Available at Accessed October 25 2013
    • Love SM:We are notmice. February 14, 2013 (Huffingtonpost.com).Available at: Http://www.huffingtonpost.com/susan-m-love/research-mice-b-2680201.html. Accessed October 25, 2013
    • We are Notmice
    • Love, S.M.1
  • 10
    • 84901613625 scopus 로고    scopus 로고
    • Now We Know. February 12, 2013 pipeline.corante.com Available a.t. Accessed October 25 2013
    • Derek L: Mouse models of inflammation are basically worthless. Now We Know. February 12, 2013 (pipeline.corante.com). Available at: Http://pipeline. corante.com/archives/2013/02/13/mouse-models-of-inflammation-are- basically-worthless-now-we-know.php. Accessed October 25, 2013
    • Mouse Models Of Inflammation Are Basically Worthless
    • Derek, L.1
  • 11
    • 84901631505 scopus 로고    scopus 로고
    • December 20, 2012 (richarddawkins.net Available at Accessed October 25 2013
    • Chu E: This is why its a mistake to cure mice instead of humans. December 20, 2012 (richarddawkins.net). Available at: Http://www.popsci.com/science/ article/2013-02/how-scientists-got-lost-curing-mice-instead-of-humans. Accessed October 25, 2013
    • This is Why Its A Mistake To Cure Mice Instead Of Humans
    • Chu, E.1
  • 13
    • 84875719538 scopus 로고    scopus 로고
    • Model organisms: Mouse models challenged
    • de Souza N: Model organisms: Mouse models challenged. Nat Methods 10(4): 288, 2013
    • (2013) Nat Methods , vol.10 , Issue.4 , pp. 288
    • De Souza, N.1
  • 14
    • 84877142535 scopus 로고    scopus 로고
    • Humanizing the mouse: In defense of murine models of critical illness
    • Perlman H, Budinger GR, Ward PA: Humanizing the mouse: In defense of murine models of critical illness. Am J Respir Crit Care Med 187(9): 898-900, 2013
    • (2013) Am J Respir Crit Care Med , vol.187 , Issue.9 , pp. 898-900
    • Perlman, H.1    Budinger, G.R.2    Ward, P.A.3
  • 16
    • 84879983546 scopus 로고    scopus 로고
    • Of mice and men: What rodent models dont tell US
    • Drake AC: Of mice and men: What rodent models dont tell us. Cell Mol Immunol 10(4):284-285, 2013
    • (2013) Cell Mol Immunol , vol.10 , Issue.4 , pp. 284-285
    • Drake, A.C.1
  • 17
    • 84901629272 scopus 로고    scopus 로고
    • Do mice make bad models?
    • February 11 2013 Available at Accessed October 25
    • Cossin D: Do Mice Make Bad Models? The Scientist. February 11, 2013. Available at: Http://www.the-scientist.com/?articles.view/articleNo/34346/title/ Do-Mice-Make-Bad-Models-/. Accessed October 25, 2013
    • (2013) Scientist
    • Cossin, D.1
  • 18
    • 84901613624 scopus 로고    scopus 로고
    • Are mice reliable models for human disease studies?
    • February 14 Available at Accessed October 25 2013
    • Barrington B: Are mice reliable models for human disease studies? Understand Nutrition, February 14, 2013. Available at: Http:// understandnutrition. com/2013/02/14/are-mice-reliable-models-for-human-disease- studies/. Accessed October 25, 2013
    • (2013) Understand Nutrition
    • Barrington, B.1
  • 19
    • 84901644504 scopus 로고    scopus 로고
    • Why mice may succeed in research when a single mouse falls short?
    • February 13 Available at Accessed October 25 2013
    • Wanner M: Why mice may succeed in research when a single mouse falls short? Genetics and Your Health Blog, February 13, 2013. Available at: Http://community.jax.org/genetics-health/b/weblog/archive/2013/02/13/ why-mice-may-succeed-in-research-when-a-single-mouse-fallsshort. aspx. Accessed October 25, 2013
    • (2013) Genetics and Your Health Blog
    • Wanner, M.1
  • 20
    • 84885656203 scopus 로고    scopus 로고
    • Use of animal models for the study of human disease-A shock society debate
    • Remick D: Use of animal models for the study of human disease-a shock society debate. Shock 40(4):345-346, 2013
    • (2013) Shock , vol.40 , Issue.4 , pp. 345-346
    • Remick, D.1
  • 21
    • 0018836213 scopus 로고
    • Cellular basis for genetically determined enhanced resistance of certain mouse strains to listeriosis
    • Sadarangani C, Skamene E, Kongshavn PA: Cellular basis for genetically determined enhanced resistance of certain mouse strains to listeriosis. Infect Immun 28(2):381-386, 1980
    • (1980) Infect Immun , vol.28 , Issue.2 , pp. 381-386
    • Sadarangani, C.1    Skamene, E.2    Kongshavn, P.A.3
  • 22
    • 0036150976 scopus 로고    scopus 로고
    • Model of differential susceptibility to mucosal Burkholderia pseudomallei infection
    • Liu B, Koo GC, Yap EH, Chua KL, Gan YH: Model of differential susceptibility to mucosal Burkholderia pseudomallei infection. Infect Immun 70(2):504-511, 2002
    • (2002) Infect Immun , vol.70 , Issue.2 , pp. 504-511
    • Liu, B.1    Koo, G.C.2    Yap, E.H.3    Chua, K.L.4    Gan, Y.H.5
  • 23
    • 0028129944 scopus 로고
    • Similar immune response to nonlethal infection with herpes simplex virus-1 in sensitive (BALB/c) and resistant (C57BL/6) strains of mice
    • Brenner GJ, Cohen N, Moynihan JA: Similar immune response to nonlethal infection with herpes simplex virus-1 in sensitive (BALB/c) and resistant (C57BL/6) strains of mice. Cell Immunol 157(2):510-524, 1994
    • (1994) Cell Immunol , vol.157 , Issue.2 , pp. 510-524
    • Brenner, G.J.1    Cohen, N.2    Moynihan, J.A.3
  • 24
    • 0028783750 scopus 로고
    • Mouse adenovirus type 1 causes a fatal hemorrhagic encephalomyelitis in adult C57BL/6 but not BALB/c mice
    • Guida JD, Fejer G, Pirofski LA, Brosnan CF, Horwitz MS: Mouse adenovirus type 1 causes a fatal hemorrhagic encephalomyelitis in adult C57BL/6 but not BALB/c mice. J Virol 69(12):7674-7681, 1995
    • (1995) J Virol , vol.69 , Issue.12 , pp. 7674-7681
    • Guida, J.D.1    Fejer, G.2    Pirofski, L.A.3    Brosnan, C.F.4    Horwitz, M.S.5
  • 25
    • 0028242631 scopus 로고
    • Immune responses to Yersinia enterocolitica in susceptible BALB/c and resistant C57BL/6 mice: An essential role for gamma interferon
    • Autenrieth IB, Beer M, Bohn E, Kaufmann SH, Heesemann J: Immune responses to Yersinia enterocolitica in susceptible BALB/c and resistant C57BL/6 mice: An essential role for gamma interferon. Infect Immun 62(6): 2590-2599, 1994
    • (1994) Infect Immun , vol.62 , Issue.6 , pp. 2590-2599
    • Autenrieth, I.B.1    Beer, M.2    Bohn, E.3    Kaufmann, S.H.4    Heesemann, J.5
  • 27
    • 84890861186 scopus 로고    scopus 로고
    • Animal models of sepsis
    • Fink MP: Animal models of sepsis. Virulence 5(1):143-153, 2014
    • (2014) Virulence , vol.5 , Issue.1 , pp. 143-153
    • Fink, M.P.1
  • 28
    • 0034243510 scopus 로고    scopus 로고
    • Effect of gender and sex hormones on immune responses following shock
    • Angele MK, Schwacha MG, Ayala A, Chaudry IH: Effect of gender and sex hormones on immune responses following shock. Shock 14(2):81-90, 2000
    • (2000) Shock , vol.14 , Issue.2 , pp. 81-90
    • Angele, M.K.1    Schwacha, M.G.2    Ayala, A.3    Chaudry, I.H.4
  • 30
    • 33645829478 scopus 로고    scopus 로고
    • Influence of gender and age on T-cell responses in a murine model of trauma-hemorrhage: Differences between circulating and tissue-fixed cells
    • Schneider CP, Schwacha MG, Chaudry IH: Influence of gender and age on T-cell responses in a murine model of trauma-hemorrhage: Differences between circulating and tissue-fixed cells. J Appl Physiol (1985) 100(3): 826-833, 2006
    • (2006) J Appl Physiol 1985 , vol.100 , Issue.3 , pp. 826-833
    • Schneider, C.P.1    Schwacha, M.G.2    Chaudry, I.H.3
  • 31
    • 33746880282 scopus 로고    scopus 로고
    • Sexual dimorphism in innate immune responses to infectious organisms
    • Marriott I, Huet-Hudson YM: Sexual dimorphism in innate immune responses to infectious organisms. Immunol Res 34(3):177-192, 2006
    • (2006) Immunol Res , vol.34 , Issue.3 , pp. 177-192
    • Marriott, I.1    Huet-Hudson, Y.M.2
  • 32
    • 70349669402 scopus 로고    scopus 로고
    • Gender difference in granulocyte dynamics and apoptosis and the role of IL-18 during endotoxin-induced systemic inflammation
    • Aoyama M, Kotani J, Usami M: Gender difference in granulocyte dynamics and apoptosis and the role of IL-18 during endotoxin-induced systemic inflammation. Shock 32(4):401-409, 2009
    • (2009) Shock , vol.32 , Issue.4 , pp. 401-409
    • Aoyama, M.1    Kotani, J.2    Usami, M.3
  • 33
    • 24344502729 scopus 로고    scopus 로고
    • The influence of gender on human innate immunity
    • Imahara SD, Jelacic S, Junker CE, Okeefe GE: The influence of gender on human innate immunity. Surgery 138(2):275-282, 2005
    • (2005) Surgery , vol.138 , Issue.2 , pp. 275-282
    • Imahara, S.D.1    Jelacic, S.2    Junker, C.E.3    Okeefe, G.E.4
  • 41
    • 0036225752 scopus 로고    scopus 로고
    • Delayed and reduced adaptive humoral immune responses in children with shigellosis compared with in adults
    • Raqib R, Qadri F, SarkEr P, Mia SM, Sansonnetti PJ, Albert MJ, Andersson J: Delayed and reduced adaptive humoral immune responses in children with shigellosis compared with in adults. Scand J Immunol 55(4):414-423, 2002
    • (2002) Scand J Immunol , vol.55 , Issue.4 , pp. 414-423
    • Raqib, R.1    Qadri, F.2    SarkEr, P.3    Mia, S.M.4    Sansonnetti, P.J.5    Albert, M.J.6    Andersson, J.7
  • 42
    • 84861190678 scopus 로고    scopus 로고
    • Characterization of TH17 responses to Streptococcus pneumoniae in humans: Comparisons between adults and children in a developed and a developing country
    • Lundgren A, Bhuiyan TR, Novak D, Kaim J, Reske A, Lu YJ, Qadri F, Malley R: Characterization of TH17 responses to Streptococcus pneumoniae in humans: Comparisons between adults and children in a developed and a developing country. Vaccine 30(26):3897-3907, 2012
    • (2012) Vaccine , vol.30 , Issue.26 , pp. 3897-3907
    • Lundgren, A.1    Bhuiyan, T.R.2    Novak, D.3    Kaim, J.4    Reske, A.5    Lu, Y.J.6    Qadri, F.7    Malley, R.8
  • 43
    • 33846178240 scopus 로고    scopus 로고
    • Impact of sex and age on bone marrow immune responses in a murine model of trauma-hemorrhage
    • Schneider CP, Schwacha MG, Chaudry IH: Impact of sex and age on bone marrow immune responses in a murine model of trauma-hemorrhage. J Appl Physiol (1985) 102(1):113-121, 2007
    • (2007) J Appl Physiol 1985 , vol.102 , Issue.1 , pp. 113-121
    • Schneider, C.P.1    Schwacha, M.G.2    Chaudry, I.H.3
  • 44
    • 2442552934 scopus 로고    scopus 로고
    • Are the immune responses different in middle-aged and young mice following bone fracture tissue trauma and hemorrhage?
    • Kang SC, Matsutani T, Choudhry MA, Schwacha MG, Rue LW, Bland KI, Chaudry IH: Are the immune responses different in middle-aged and young mice following bone fracture, tissue trauma and hemorrhage? Cytokine 26(5):223-230, 2004
    • (2004) Cytokine , vol.26 , Issue.5 , pp. 223-230
    • Kang, S.C.1    Matsutani, T.2    Choudhry, M.A.3    Schwacha, M.G.4    Rue, L.W.5    Bland, K.I.6    Chaudry, I.H.7
  • 45
    • 84873555175 scopus 로고    scopus 로고
    • Reduced neutrophil chemotaxis and infiltration contributes to delayed resolution of cutaneous wound infection with advanced age
    • Brubaker AL, Rendon JL, Ramirez L, Choudhry MA, Kovacs EJ: Reduced neutrophil chemotaxis and infiltration contributes to delayed resolution of cutaneous wound infection with advanced age. J Immunol 190(4): 1746-1757, 2013
    • (2013) J Immunol , vol.190 , Issue.4 , pp. 1746-1757
    • Brubaker, A.L.1    Rendon, J.L.2    Ramirez, L.3    Choudhry, M.A.4    Kovacs, E.J.5
  • 46
    • 0029671119 scopus 로고    scopus 로고
    • Age-associated differences in TNF-alpha and nitric oxide production in endotoxic mice
    • Chorinchath BB, Kong LY, Mao L, McCallum RE: Age-associated differences in TNF-alpha and nitric oxide production in endotoxic mice. J Immunol 156(4):1525-1530, 1996
    • (1996) J Immunol , vol.156 , Issue.4 , pp. 1525-1530
    • Chorinchath, B.B.1    Kong, L.Y.2    Mao, L.3    McCallum, R.E.4
  • 51
    • 0029738469 scopus 로고    scopus 로고
    • Immune function is more compromised after closed bone fracture and hemorrhagic shock than hemorrhage alone
    • Wichmann MW, Zellweger R, DeMaso CM, Ayala A, Williams C, Chaudry IH: Immune function is more compromised after closed bone fracture and hemorrhagic shock than hemorrhage alone. Arch Surg 131(9):995-1000, 1996
    • (1996) Arch Surg , vol.131 , Issue.9 , pp. 995-1000
    • Wichmann, M.W.1    Zellweger, R.2    DeMaso, C.M.3    Ayala, A.4    Williams, C.5    Chaudry, I.H.6
  • 52
    • 0031880606 scopus 로고    scopus 로고
    • Severe depression of host immune functions following closed-bone fracture, soft-tissue trauma, and hemorrhagic shock
    • Wichmann MW, Ayala A, Chaudry IH: Severe depression of host immune functions following closed-bone fracture, soft-tissue trauma, and hemorrhagic shock. Crit Care Med 26(8):1372-1378, 1998
    • (1998) Crit Care Med , vol.26 , Issue.8 , pp. 1372-1378
    • Wichmann, M.W.1    Ayala, A.2    Chaudry, I.H.3
  • 54
    • 0036081355 scopus 로고    scopus 로고
    • Gene Expression Omnibus: NCBI gene expression and hybridization array data repository
    • Edgar R, Domrachev M, Lash AE: Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res 30(1):207-210, 2002
    • (2002) Nucleic Acids Res , vol.30 , Issue.1 , pp. 207-210
    • Edgar, R.1    Domrachev, M.2    Lash, A.E.3
  • 57
    • 84887073310 scopus 로고    scopus 로고
    • Role of biomarkers in sepsis care
    • Samraj RS, Zingarelli B, Wong HR: Role of biomarkers in sepsis care. Shock 40(5):358-365, 2013
    • (2013) Shock , vol.40 , Issue.5 , pp. 358-365
    • Samraj, R.S.1    Zingarelli, B.2    Wong, H.R.3
  • 58
    • 84880111010 scopus 로고    scopus 로고
    • Practical application of point-of-care coagulation testing to guide treatment decisions in trauma
    • Schochl H, Voelckel W, Grassetto A, Schlimp CJ: Practical application of point-of-care coagulation testing to guide treatment decisions in trauma. J Trauma Acute Care Surg 74(6):1587-1598, 2013
    • (2013) J Trauma Acute Care Surg , vol.74 , Issue.6 , pp. 1587-1598
    • Schochl, H.1    Voelckel, W.2    Grassetto, A.3    Schlimp, C.J.4
  • 59
    • 34447542644 scopus 로고    scopus 로고
    • Evaluation of white blood cell count, neutrophil percentage, and elevated temperature as predictors of bloodstream infection in burn patients
    • Murray CK, Hoffmaster RM, Schmit DR, Hospenthal DR, Ward JA, Cancio LC, Wolf SE: Evaluation of white blood cell count, neutrophil percentage, and elevated temperature as predictors of bloodstream infection in burn patients. Arch Surg 142(7):639-642, 2007
    • (2007) Arch Surg , vol.142 , Issue.7 , pp. 639-642
    • Murray, C.K.1    Hoffmaster, R.M.2    Schmit, D.R.3    Hospenthal, D.R.4    Ward, J.A.5    Cancio, L.C.6    Wolf, S.E.7
  • 60
    • 84866249797 scopus 로고    scopus 로고
    • Umbilical blood biomarkers for predicting early-onset neonatal sepsis
    • Fan Y, Yu JL: Umbilical blood biomarkers for predicting early-onset neonatal sepsis. World J Pediatr 8(2):101-108, 2012
    • (2012) World J Pediatr , vol.8 , Issue.2 , pp. 101-108
    • Fan, Y.1    Yu, J.L.2
  • 61
    • 36549019937 scopus 로고    scopus 로고
    • Systemic inflammation after trauma
    • Lenz A, Franklin GA, Cheadle WG: Systemic inflammation after trauma. Injury 38(12):1336-1345, 2007
    • (2007) Injury , vol.38 , Issue.12 , pp. 1336-1345
    • Lenz, A.1    Franklin, G.A.2    Cheadle, W.G.3
  • 62
    • 46149105672 scopus 로고    scopus 로고
    • The cytokine storm and factors determining the sequence and severity of organ dysfunction in multiple organ dysfunction syndrome
    • Wang H, Ma S: The cytokine storm and factors determining the sequence and severity of organ dysfunction in multiple organ dysfunction syndrome. Am J Emerg Med 26(6):711-715, 2008
    • (2008) Am J Emerg Med , vol.26 , Issue.6 , pp. 711-715
    • Wang, H.1    Ma, S.2
  • 63
    • 33745932547 scopus 로고    scopus 로고
    • Compartmentalization of the inflammatory response in sepsis and SIRS
    • Cavaillon JM, Annane D: Compartmentalization of the inflammatory response in sepsis and SIRS. J Endotoxin Res 12(3):151-170, 2006
    • (2006) J Endotoxin Res , vol.12 , Issue.3 , pp. 151-170
    • Cavaillon, J.M.1    Annane, D.2
  • 64
    • 0034913320 scopus 로고    scopus 로고
    • Immunodepression in sepsis and SIRS assessed by ex vivo cytokine production is not a generalized phenomenon: A review
    • Cavaillon JM, Adib-Conquy M, Cloez-Tayarani I, Fitting C: Immunodepression in sepsis and SIRS assessed by ex vivo cytokine production is not a generalized phenomenon: A review. J Endotoxin Res 7(2):85-93, 2001
    • (2001) J Endotoxin Res , vol.7 , Issue.2 , pp. 85-93
    • Cavaillon, J.M.1    Adib-Conquy, M.2    Cloez-Tayarani, I.3    Fitting, C.4
  • 65
    • 0035986840 scopus 로고    scopus 로고
    • Differential expression and tissue compartmentalization of the inflammatory response following thermal injury
    • Schwacha MG, Schneider CP, Chaudry IH: Differential expression and tissue compartmentalization of the inflammatory response following thermal injury. Cytokine 17(5):266-274, 2002
    • (2002) Cytokine , vol.17 , Issue.5 , pp. 266-274
    • Schwacha, M.G.1    Schneider, C.P.2    Chaudry, I.H.3
  • 66
    • 34548177492 scopus 로고    scopus 로고
    • Nitric oxide in shock
    • Cauwels A: Nitric oxide in shock. Kidney Int 72(5):557-565, 2007
    • (2007) Kidney Int , vol.72 , Issue.5 , pp. 557-565
    • Cauwels, A.1
  • 67
    • 83455164828 scopus 로고    scopus 로고
    • LPS-induced murine systemic inflammation is driven by parenchymal cell activation and exclusively predicted by early MCP-1 plasma levels
    • Juskewitch JE, Knudsen BE, Platt JL, Nath KA, Knutson KL, Brunn GJ, Grande JP: LPS-induced murine systemic inflammation is driven by parenchymal cell activation and exclusively predicted by early MCP-1 plasma levels. Am J Pathol 180(1):32-40, 2012
    • (2012) Am J Pathol , vol.180 , Issue.1 , pp. 32-40
    • Juskewitch, J.E.1    Knudsen, B.E.2    Platt, J.L.3    Nath, K.A.4    Knutson, K.L.5    Brunn, G.J.6    Grande, J.P.7
  • 68
    • 84870842886 scopus 로고    scopus 로고
    • Disparate roles of marrow- And parenchymal cellYderived TLR4 signaling in murine LPS-induced systemic inflammation
    • Juskewitch JE, Platt JL, Knudsen BE, Knutson KL, Brunn GJ, Grande JP: Disparate roles of marrow- And parenchymal cellYderived TLR4 signaling in murine LPS-induced systemic inflammation. Sci Rep 2:918, 2012
    • Sci Rep , vol.2 , Issue.918 , pp. 2012
    • Juskewitch, J.E.1    Platt, J.L.2    Knudsen, B.E.3    Knutson, K.L.4    Brunn, G.J.5    Grande, J.P.6
  • 69
    • 0041808735 scopus 로고    scopus 로고
    • Induction of procalcitonin and proinflammatory cytokines in an anhepatic baboon endotoxin shock model
    • Meisner M, Muller V, Khakpour Z, Toegel E, Redl H: Induction of procalcitonin and proinflammatory cytokines in an anhepatic baboon endotoxin shock model. Shock 19(2):187-190, 2003
    • (2003) Shock , vol.19 , Issue.2 , pp. 187-190
    • Meisner, M.1    Muller, V.2    Khakpour, Z.3    Toegel, E.4    Redl, H.5
  • 70
    • 0028864991 scopus 로고
    • A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion
    • Jung HC, Eckmann L, Yang SK, Panja A, Fierer J, Morzycka-Wroblewska E, Kagnoff MF: A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion. J Clin Invest 95(1):55-65, 1995
    • (1995) J Clin Invest , vol.95 , Issue.1 , pp. 55-65
    • Jung, H.C.1    Eckmann, L.2    Yang, S.K.3    Panja, A.4    Fierer, J.5    Morzycka-Wroblewska, E.6    Kagnoff, M.F.7
  • 72
    • 33846239963 scopus 로고    scopus 로고
    • Tissue compartment-specific role of estrogen receptor subtypes in immune cell cytokine production following trauma-hemorrhage
    • Suzuki T, Shimizu T, Yu HP, Hsieh YC, Choudhry MA, Schwacha MG, Chaudry IH: Tissue compartment-specific role of estrogen receptor subtypes in immune cell cytokine production following trauma-hemorrhage. J Appl Physiol (1985) 102(1):163-168, 2007
    • (2007) J Appl Physiol 1985 , vol.102 , Issue.1 , pp. 163-168
    • Suzuki, T.1    Shimizu, T.2    Yu, H.P.3    Hsieh, Y.C.4    Choudhry, M.A.5    Schwacha, M.G.6    Chaudry, I.H.7
  • 73
    • 0026316281 scopus 로고
    • Hemorrhage induces enhanced Kupffer cell cytotoxicity while decreasing peritoneal or splenic macrophage capacity. Involvement of cell-associated tumor necrosis factor and reactive nitrogen
    • Ayala A, Perrin MM, Wang P, Ertel W, Chaudry IH: Hemorrhage induces enhanced Kupffer cell cytotoxicity while decreasing peritoneal or splenic macrophage capacity. Involvement of cell-associated tumor necrosis factor and reactive nitrogen. J Immunol 147(12):4147-4154, 1991
    • (1991) J Immunol , vol.147 , Issue.12 , pp. 4147-4154
    • Ayala, A.1    Perrin, M.M.2    Wang, P.3    Ertel, W.4    Chaudry, I.H.5
  • 74
    • 0028902976 scopus 로고
    • Cytokine gene expression in splenic macrophages and Kupffer cells following haemorrhage
    • Zhu XL, Zellweger R, Zhu XH, Ayala A, Chaudry IH: Cytokine gene expression in splenic macrophages and Kupffer cells following haemorrhage. Cytokine 7(1):8-14, 1995
    • (1995) Cytokine , vol.7 , Issue.1 , pp. 8-14
    • Zhu, X.L.1    Zellweger, R.2    Zhu, X.H.3    Ayala, A.4    Chaudry, I.H.5
  • 75
    • 0028459375 scopus 로고
    • Differential alterations in cyclic nucleotide levels in Kupffer cells and hepatocytes following traumahemorrhage and resuscitation
    • Wang P, Ba ZF, Morrison MH, Chaudry IH: Differential alterations in cyclic nucleotide levels in Kupffer cells and hepatocytes following traumahemorrhage and resuscitation. Shock 1(6):438-442, 1994
    • (1994) Shock , vol.1 , Issue.6 , pp. 438-442
    • Wang, P.1    Ba, Z.F.2    Morrison, M.H.3    Chaudry, I.H.4
  • 76
    • 41149104463 scopus 로고    scopus 로고
    • Gene signatures reflect the marked heterogeneity of tissue-resident macrophages
    • Gorgani NN, Ma Y, Clark HF: Gene signatures reflect the marked heterogeneity of tissue-resident macrophages. Immunol Cell Biol 86(3):246-254, 2008
    • (2008) Immunol Cell Biol , vol.86 , Issue.3 , pp. 246-254
    • Gorgani, N.N.1    Ma, Y.2    Clark, H.F.3
  • 77
    • 12544254834 scopus 로고    scopus 로고
    • Inflammation and host response to injury investigators: Acute inflammatory response to endotoxin in mice and humans
    • Copeland S, Warren HS, Lowry SF, Calvano SE, Remick DG: Inflammation and host response to injury investigators: Acute inflammatory response to endotoxin in mice and humans. Clin Diagn Lab Immunol 12(1):60-67, 2005
    • (2005) Clin Diagn Lab Immunol , vol.12 , Issue.1 , pp. 60-67
    • Copeland, S.1    Warren, H.S.2    Lowry, S.F.3    Calvano, S.E.4    Remick, D.G.5
  • 78
    • 75149172745 scopus 로고    scopus 로고
    • The acute inflammatory response in trauma/hemorrhage and traumatic brain injury: Current state and emerging prospects
    • Namas R, Ghuma A, Hermus L, Zamora R, Okonkwo DO, Billiar TR, Vodovotz Y: The acute inflammatory response in trauma/hemorrhage and traumatic brain injury: Current state and emerging prospects. Libyan J Med 4(3):97-103, 2009
    • (2009) Libyan J Med , vol.4 , Issue.3 , pp. 97-103
    • Namas, R.1    Ghuma, A.2    Hermus, L.3    Zamora, R.4    Okonkwo, D.O.5    Billiar, T.R.6    Vodovotz, Y.7
  • 79
    • 72949092495 scopus 로고    scopus 로고
    • Involvement of pro- And antiinflammatory cytokines and chemokines in the pathophysiology of traumatic brain injury
    • Ziebell JM, Morganti-Kossmann MC: Involvement of pro- And antiinflammatory cytokines and chemokines in the pathophysiology of traumatic brain injury. Neurotherapeutics 7(1):22-30, 2010
    • (2010) Neurotherapeutics , vol.7 , Issue.1 , pp. 22-30
    • Ziebell, J.M.1    Morganti-Kossmann, M.C.2
  • 80
    • 18644382957 scopus 로고    scopus 로고
    • Different mRNA and protein expression of matrix metalloproteinases 2 and 9 and tissue inhibitor of metalloproteinases 1 in benign and malignant prostate tissue
    • Lichtinghagen R, Musholt PB, Lein M, Romer A, Rudolph B, Kristiansen G, Hauptmann S, Schnorr D, Loening SA, Jung K: Different mRNA and protein expression of matrix metalloproteinases 2 and 9 and tissue inhibitor of metalloproteinases 1 in benign and malignant prostate tissue. Eur Urol 42(4): 398-406, 2002
    • (2002) Eur Urol , vol.42 , Issue.4 , pp. 398-406
    • Lichtinghagen, R.1    Musholt, P.B.2    Lein, M.3    Romer, A.4    Rudolph, B.5    Kristiansen, G.6    Hauptmann, S.7    Schnorr, D.8    Loening, S.A.9    Jung, K.10
  • 82
    • 0036052093 scopus 로고    scopus 로고
    • Genome-wide study of gene copy numbers, transcripts, and protein levels in pairs of non-invasive and invasive human transitional cell carcinomas
    • Orntoft TF, Thykjaer T, Waldman FM, Wolf H, Celis JE: Genome-wide study of gene copy numbers, transcripts, and protein levels in pairs of non-invasive and invasive human transitional cell carcinomas. Mol Cell Proteomics 1(1):37-45, 2002
    • (2002) Mol Cell Proteomics , vol.1 , Issue.1 , pp. 37-45
    • Orntoft, T.F.1    Thykjaer, T.2    Waldman, F.M.3    Wolf, H.4    Celis, J.E.5
  • 84
    • 0030895921 scopus 로고    scopus 로고
    • A comparison of selected mRNA and protein abundances in human liver
    • Anderson L, Seilhamer J: A comparison of selected mRNA and protein abundances in human liver. Electrophoresis 18(3-4):533-537, 1997
    • (1997) Electrophoresis , vol.18 , Issue.3-4 , pp. 533-537
    • Anderson, L.1    Seilhamer, J.2
  • 85
    • 0141920354 scopus 로고    scopus 로고
    • Comparing protein abundance and mRNA expression levels on a genomic scale
    • Greenbaum D, Colangelo C, Williams K, Gerstein M: Comparing protein abundance and mRNA expression levels on a genomic scale. Genome Biol 4(9):117, 2003
    • (2003) Genome Biol , vol.4 , Issue.9 , pp. 117
    • Greenbaum, D.1    Colangelo, C.2    Williams, K.3    Gerstein, M.4
  • 86
    • 84865455765 scopus 로고    scopus 로고
    • Trauma equals dangerVdamage control by the immune system
    • Stoecklein VM, Osuka A, Lederer JA: Trauma equals dangerVdamage control by the immune system. J Leukoc Biol 92(3):539-551, 2012
    • (2012) J Leukoc Biol , vol.92 , Issue.3 , pp. 539-551
    • Stoecklein, V.M.1    Osuka, A.2    Lederer, J.A.3
  • 90
    • 36348976981 scopus 로고    scopus 로고
    • Structural analysis of the human galectin-9 N-terminal carbohydrate recognition domain reveals unexpected properties that differ from the mouse orthologue
    • Nagae M, Nishi N, Nakamura-Tsuruta S, Hirabayashi J, Wakatsuki S, Kato R: Structural analysis of the human galectin-9 N-terminal carbohydrate recognition domain reveals unexpected properties that differ from the mouse orthologue. J Mol Biol 375(1):119-135, 2008
    • (2008) J Mol Biol , vol.375 , Issue.1 , pp. 119-135
    • Nagae, M.1    Nishi, N.2    Nakamura-Tsuruta, S.3    Hirabayashi, J.4    Wakatsuki, S.5    Kato, R.6
  • 92
    • 84864317105 scopus 로고    scopus 로고
    • Unstressing intemperate models: How cold stress undermines mouse modeling
    • Karp CL: Unstressing intemperate models: How cold stress undermines mouse modeling. J Exp Med 209(6):1069-1074, 2012
    • (2012) J Exp Med , vol.209 , Issue.6 , pp. 1069-1074
    • Karp, C.L.1
  • 93
    • 0032820318 scopus 로고    scopus 로고
    • Sepsis: Lessons learned in the last century and future directions
    • Chaudry IH: Sepsis: Lessons learned in the last century and future directions. Arch Surg 134(9):922-929, 1999
    • (1999) Arch Surg , vol.134 , Issue.9 , pp. 922-929
    • Chaudry, I.H.1
  • 95
    • 84883880887 scopus 로고    scopus 로고
    • Look back in angerVwhat clinical studies tell us about preclinical work
    • Hartung T: Look back in angerVwhat clinical studies tell us about preclinical work. ALTEX 30(3):275-291, 2013
    • (2013) ALTEX , vol.30 , Issue.3 , pp. 275-291
    • Hartung, T.1
  • 96
    • 84885601101 scopus 로고    scopus 로고
    • Whos afraid of peer review?
    • Bohannon J: Whos afraid of peer review? Science 342(6154):60-65, 2013
    • (2013) Science , vol.342 , Issue.6154 , pp. 60-65
    • Bohannon, J.1
  • 98
    • 0022411888 scopus 로고
    • Passive immunization against cachectin/ tumor necrosis factor protects mice from lethal effect of endotoxin
    • Beutler B, Milsark IW, Cerami AC: Passive immunization against cachectin/ tumor necrosis factor protects mice from lethal effect of endotoxin. Science 229(4716):869-871, 1985
    • (1985) Science , vol.229 , Issue.4716 , pp. 869-871
    • Beutler, B.1    Milsark, I.W.2    Cerami, A.C.3
  • 99
    • 0018964280 scopus 로고
    • Sepsis and septic shockVa review of laboratory models and a proposal
    • Wichterman KA, Baue AE, Chaudry IH: Sepsis and septic shockVa review of laboratory models and a proposal. J Surg Res 29(2):189-201, 1980
    • (1980) J Surg Res , vol.29 , Issue.2 , pp. 189-201
    • Wichterman, K.A.1    Baue, A.E.2    Chaudry, I.H.3
  • 101
    • 0029348036 scopus 로고
    • Blockade of tumor necrosis factor reduces lipopolysaccharide lethality, but not the lethality of cecal ligation and puncture
    • Remick D, Manohar P, Bolgos G, Rodriguez J, Moldawer L, Wollenberg G: Blockade of tumor necrosis factor reduces lipopolysaccharide lethality, but not the lethality of cecal ligation and puncture. Shock 4(2):89-95, 1995
    • (1995) Shock , vol.4 , Issue.2 , pp. 89-95
    • Remick, D.1    Manohar, P.2    Bolgos, G.3    Rodriguez, J.4    Moldawer, L.5    Wollenberg, G.6
  • 102
    • 0026317729 scopus 로고
    • Prophylaxis and treatment of newborn endotoxic shock with anti-lipid a monoclonal antibodies
    • Goto M, Zeller WP, Hurley RM, Jong JS, Lee CH: Prophylaxis and treatment of newborn endotoxic shock with anti-lipid. A monoclonal antibodies. Circ Shock 35(1):60-64, 1991
    • (1991) Circ Shock , vol.35 , Issue.1 , pp. 60-64
    • Goto, M.1    Zeller, W.P.2    Hurley, R.M.3    Jong, J.S.4    Lee, C.H.5
  • 103
    • 0025225333 scopus 로고
    • Interleukin-1 receptor antagonist reduces mortality from endotoxin shock
    • Ohlsson K, Bjork P, Bergenfeldt M, Hageman R, Thompson RC: Interleukin-1 receptor antagonist reduces mortality from endotoxin shock. Nature 348(6301): 550-552, 1990
    • (1990) Nature , vol.348 , Issue.6301 , pp. 550-552
    • Ohlsson, K.1    Bjork, P.2    Bergenfeldt, M.3    Hageman, R.4    Thompson, R.C.5
  • 107
    • 84888325490 scopus 로고    scopus 로고
    • Sepsis-induced immunosuppression: From cellular dysfunctions to immunotherapy
    • Hotchkiss RS, Monneret G, Payen D: Sepsis-induced immunosuppression: From cellular dysfunctions to immunotherapy. Nat Rev Immunol 13(12): 862-874, 2013
    • (2013) Nat Rev Immunol , vol.13 , Issue.12 , pp. 862-874
    • Hotchkiss, R.S.1    Monneret, G.2    Payen, D.3
  • 108
    • 84255183707 scopus 로고    scopus 로고
    • The search for effective therapy for sepsis: Back to the drawing board?
    • Angus DS: The search for effective therapy for sepsis: Back to the drawing board? JAMA 306(23):2614-2615, 2011
    • (2011) JAMA , vol.306 , Issue.23 , pp. 2614-2615
    • Angus, D.S.1
  • 109
    • 8544262221 scopus 로고    scopus 로고
    • Efficacy and safety of the monoclonal anti-tumor necrosis factor antibody F(ab¶)2 fragment afelimomab in patients with severe sepsis and elevated interleukin-6 levels
    • Panacek EA, Marshall JC, Albertson TE, Johnson DH, Johnson S, MacArthur RD, Miller M, Barchuk WT, Fischkoff S, Kaul M, et al.: Efficacy and safety of the monoclonal anti-tumor necrosis factor antibody F(ab¶)2 fragment afelimomab in patients with severe sepsis and elevated interleukin-6 levels. Crit Care Med 32(11):2173-2182, 2004
    • (2004) Crit Care Med , vol.32 , Issue.11 , pp. 2173-2182
    • Panacek, E.A.1    Marshall, J.C.2    Albertson, T.E.3    Johnson, D.H.4    Johnson, S.5    MacArthur, R.D.6    Miller, M.7    Barchuk, W.T.8    Fischkoff, S.9    Kaul, M.10
  • 110
    • 67650486328 scopus 로고    scopus 로고
    • Stratification is the key: Inflammatory biomarkers accurately direct immunomodulatory therapy in experimental sepsis
    • Osuchowski MF, Connett J, Welch K, Granger J, Remick DG: Stratification is the key: Inflammatory biomarkers accurately direct immunomodulatory therapy in experimental sepsis. Crit Care Med 37(5):1567-1573, 2009
    • (2009) Crit Care Med , vol.37 , Issue.5 , pp. 1567-1573
    • Osuchowski, M.F.1    Connett, J.2    Welch, K.3    Granger, J.4    Remick, D.G.5
  • 111
    • 33846630040 scopus 로고    scopus 로고
    • Humanized mice in translational biomedical research
    • Shultz LD, Ishikawa F, Greiner DL: Humanized mice in translational biomedical research. Nat Rev Immunol 7(2):118-130, 2007
    • (2007) Nat Rev Immunol , vol.7 , Issue.2 , pp. 118-130
    • Shultz, L.D.1    Ishikawa, F.2    Greiner, D.L.3
  • 112
  • 113
    • 84877152452 scopus 로고    scopus 로고
    • Humanized mice, a new model to study the influence of drug treatment on neonatal sepsis
    • Ernst W, Zimara N, Hanses F, Männel DN, Seelbacj-Gobel B, Wege AK: Humanized mice, a new model to study the influence of drug treatment on neonatal sepsis. Infect Immun 81(5):1520-1531, 2013
    • (2013) Infect Immun , vol.81 , Issue.5 , pp. 1520-1531
    • Ernst, W.1    Zimara, N.2    Hanses, F.3    Männel, D.N.4    Seelbacj-Gobel, B.5    Wege, A.K.6
  • 115
    • 84857433366 scopus 로고    scopus 로고
    • Ten years of the Collaborative Cross
    • Threadgill DW, Churchill GA.: Ten years of the Collaborative Cross. Genetics 190(2):291-294, 2012
    • (2012) Genetics , vol.190 , Issue.2 , pp. 291-294
    • Threadgill, D.W.1    Churchill, G.A.2
  • 116
    • 0026585007 scopus 로고
    • Anti-tumor necrosis factor antibody therapy fails to prevent lethality after cecal ligation and puncture or endotoxemia
    • Eskandari MK, Bolgos G, Miller C, Nguyen DT, DeForge LE, Remick DG: Anti-tumor necrosis factor antibody therapy fails to prevent lethality after cecal ligation and puncture or endotoxemia. J Immunol 148(9):2724-2730, 1992
    • (1992) J Immunol , vol.148 , Issue.9 , pp. 2724-2730
    • Eskandari, M.K.1    Bolgos, G.2    Miller, C.3    Nguyen, D.T.4    DeForge, L.E.5    Remick, D.G.6
  • 117
    • 0029132699 scopus 로고
    • CDP571, a humanized antibody to human tumor necrosis factor-alpha: Safety, pharmacokinetics, immune response, and influence of the antibody on cytokine concentrations in patients with septic shock
    • CPD571 Sepsis Study Group
    • Dhainaut JF, Vincent JL, Richard C, Lejeune P, Martin C, Fierobe L, Stephens S, Ney UM, Sopwith M: CDP571, a humanized antibody to human tumor necrosis factor-alpha: Safety, pharmacokinetics, immune response, and influence of the antibody on cytokine concentrations in patients with septic shock. CPD571 Sepsis Study Group. Crit Care Med 23(9):1461-1469, 1995
    • (1995) Crit Care Med , vol.23 , Issue.9 , pp. 1461-1469
    • Dhainaut, J.F.1    Vincent, J.L.2    Richard, C.3    Lejeune, P.4    Martin, C.5    Fierobe, L.6    Stephens, S.7    Ney, U.M.8    Sopwith, M.9
  • 118
    • 9344246862 scopus 로고    scopus 로고
    • Assessment of the safety and efficacy of the monoclonal anti-tumor necrosis factor antibodyfragment, MAK 195F, in patients with sepsis and septic shock: A multicenter, randomized, placebo-controlled, dose-ranging study
    • Reinhart K, Wiegand-Lohnert C, Grimminger F, Kaul M, Withington S, Treacher D, Eckart J, Willatts S, Bouza C, Krausch D, et al.: Assessment of the safety and efficacy of the monoclonal anti-tumor necrosis factor antibodyfragment, MAK 195F, in patients with sepsis and septic shock: A multicenter, randomized, placebo-controlled, dose-ranging study. Crit Care Med 24(5): 733-742, 1996
    • (1996) Crit Care Med , vol.24 , Issue.5 , pp. 733-742
    • Reinhart, K.1    Wiegand-Lohnert, C.2    Grimminger, F.3    Kaul, M.4    Withington, S.5    Treacher, D.6    Eckart, J.7    Willatts, S.8    Bouza, C.9    Krausch, D.10
  • 119
    • 0029845610 scopus 로고    scopus 로고
    • Prevention of Jarisch-Herxheimer reactions by treatment with antibodies against tumor necrosis factor alpha
    • Fekade D, Knox K, Hussein K, Melka A, Lalloo DG, Coxon RE, Warrell DA: Prevention of Jarisch-Herxheimer reactions by treatment with antibodies against tumor necrosis factor alpha. N Engl J Med 335(5):311-315, 1996
    • (1996) N Engl J Med , vol.335 , Issue.5 , pp. 311-315
    • Fekade, D.1    Knox, K.2    Hussein, K.3    Melka, A.4    Lalloo, D.G.5    Coxon, R.E.6    Warrell, D.A.7
  • 121
    • 84855433653 scopus 로고    scopus 로고
    • Early initiation of low-dose corticosteroid therapy in the management of septic shock: A retrospective observational study
    • R3
    • Park HY, Suh GY, Song JU, Yoo H, Jo IJ, Shin TG, Lim SY, Woo S, Jeon K: Early initiation of low-dose corticosteroid therapy in the management of septic shock: A retrospective observational study. Crit Care 16(1):R3, 2012
    • (2012) Crit Care , vol.16 , Issue.1
    • Park, H.Y.1    Suh, G.Y.2    Song, J.U.3    Yoo, H.4    Jo, I.J.5    Shin, T.G.6    Lim, S.Y.7    Woo, S.8    Jeon, K.9
  • 124
    • 51049101334 scopus 로고    scopus 로고
    • Adenosine receptors: Therapeutic aspects for inflammatory and immune diseases
    • Haskó G, Linden J, Cronstein B, Pacher P: Adenosine receptors: Therapeutic aspects for inflammatory and immune diseases. Nat Rev Drug Discov 7(9):759-770, 2008
    • (2008) Nat Rev Drug Discov , vol.7 , Issue.9 , pp. 759-770
    • Haskó, G.1    Linden, J.2    Cronstein, B.3    Pacher, P.4
  • 125
    • 0033565425 scopus 로고    scopus 로고
    • Mechanisms of lung neutrophil activation after hemorrhage or endotoxemia: Roles of reactive oxygen intermediates, NF-kappa B, and cyclic AMP response element binding protein
    • Shenkar R, Abraham E: Mechanisms of lung neutrophil activation after hemorrhage or endotoxemia: Roles of reactive oxygen intermediates, NF-kappa B, and cyclic AMP response element binding protein. J Immunol 163(2):954-962, 1999
    • (1999) J Immunol , vol.163 , Issue.2 , pp. 954-962
    • Shenkar, R.1    Abraham, E.2
  • 126
    • 0035164344 scopus 로고    scopus 로고
    • Activation of extracellular signal-regulated kinases, NF-kappa B, and cyclic adenosine 5¶-monophosphate response element-binding protein in lung neutrophils occurs by differing mechanisms after hemorrhage or endotoxemia
    • Abraham E, Arcaroli J, Shenkar R: Activation of extracellular signal-regulated kinases, NF-kappa B, and cyclic adenosine 5¶-monophosphate response element-binding protein in lung neutrophils occurs by differing mechanisms after hemorrhage or endotoxemia. J Immunol 166(1):522-530, 2001
    • (2001) J Immunol , vol.166 , Issue.1 , pp. 522-530
    • Abraham, E.1    Arcaroli, J.2    Shenkar, R.3
  • 127
    • 33744917518 scopus 로고    scopus 로고
    • Peripheral blood neutrophil activation patterns are associated with pulmonary inflammatory responses to lipopolysaccharide in humans
    • Abraham E, Nick JA, Azam T, Kim SH, Mira JP, Svetkauskaite D, He Q, Zamora M, Murphy J, Park JS, et al.: Peripheral blood neutrophil activation patterns are associated with pulmonary inflammatory responses to lipopolysaccharide in humans. J Immunol 176(12):7753-7760, 2006
    • (2006) J Immunol , vol.176 , Issue.12 , pp. 7753-7760
    • Abraham, E.1    Nick, J.A.2    Azam, T.3    Kim, S.H.4    Mira, J.P.5    Svetkauskaite, D.6    He, Q.7    Zamora, M.8    Murphy, J.9    Park, J.S.10
  • 128
    • 0038132126 scopus 로고    scopus 로고
    • Early alterations in neutrophil activation are associated with outcome in acute lung injury
    • Yang KY, Arcaroli JJ, Abraham E: Early alterations in neutrophil activation are associated with outcome in acute lung injury. Am J Respir Crit Care 167(11):1567-1574, 2003
    • (2003) Am J Respir Crit Care , vol.167 , Issue.11 , pp. 1567-1574
    • Yang, K.Y.1    Arcaroli, J.J.2    Abraham, E.3
  • 129
    • 33746190736 scopus 로고    scopus 로고
    • Circulating cytokine/ inhibitor profiles reshape the understanding of the SIRS/CARS continuum in sepsis and predict mortality
    • Osuchowski MF, Welch K, Siddiqui J, Remick DG: Circulating cytokine/ inhibitor profiles reshape the understanding of the SIRS/CARS continuum in sepsis and predict mortality. J Immunol 177(3):1967-1974, 2006
    • (2006) J Immunol , vol.177 , Issue.3 , pp. 1967-1974
    • Osuchowski, M.F.1    Welch, K.2    Siddiqui, J.3    Remick, D.G.4
  • 130
    • 84867903811 scopus 로고    scopus 로고
    • Sepsis chronically in MARS: Systemic cytokine responses are always mixed regardless of the outcome, magnitude, or phase of sepsis
    • Osuchowski MF, Craciun F, Weixelbaumer KM, Duffy ER, Remick DG: Sepsis chronically in MARS: Systemic cytokine responses are always mixed regardless of the outcome, magnitude, or phase of sepsis. J Immunol 189(9): 4648-4656, 2012
    • (2012) J Immunol , vol.189 , Issue.9 , pp. 4648-4656
    • Osuchowski, M.F.1    Craciun, F.2    Weixelbaumer, K.M.3    Duffy, E.R.4    Remick, D.G.5
  • 132
    • 84860237238 scopus 로고    scopus 로고
    • Mixed antagonist response and sepsis severity-dependent dysbalance of pro- And anti-inflammatory responses at the onset of postoperative sepsis
    • Novotny AR, Reim D, Assfalg V, Altmayr F, Friess HM, Emmanuel K, Holzmann B: Mixed antagonist response and sepsis severity-dependent dysbalance of pro- And anti-inflammatory responses at the onset of postoperative sepsis. Immunobiology 217(6):616-621, 2012
    • (2012) Immunobiology , vol.217 , Issue.6 , pp. 616-621
    • Novotny, A.R.1    Reim, D.2    Assfalg, V.3    Altmayr, F.4    Friess, H.M.5    Emmanuel, K.6    Holzmann, B.7
  • 133
    • 0036595292 scopus 로고    scopus 로고
    • Six at six: Interleukin-6 measured 6 h after the initiation of sepsis predicts mortality over 3 days
    • Remick DG, Bolgos GR, Siddiqui J, Shin J, Nemzek JA: Six at six: Interleukin-6 measured 6 h after the initiation of sepsis predicts mortality over 3 days. Shock 17(6):463-467, 2002
    • (2002) Shock , vol.17 , Issue.6 , pp. 463-467
    • Remick, D.G.1    Bolgos, G.R.2    Siddiqui, J.3    Shin, J.4    Nemzek, J.A.5
  • 135
    • 0024529891 scopus 로고
    • The complex pattern of cytokines in serum from patients with meningococcal septic shock association between interleukin 6, interleukin 1, and fatal outcome
    • Waage A, Brandtzaeg P, Halstensen A, Kierulf P, Espevik T: The complex pattern of cytokines in serum from patients with meningococcal septic shock. Association between interleukin 6, interleukin 1, and fatal outcome. J Exp Med 169(1):333-338, 1989
    • (1989) J Exp Med , vol.169 , Issue.1 , pp. 333-338
    • Waage, A.1    Brandtzaeg, P.2    Halstensen, A.3    Kierulf, P.4    Espevik, T.5
  • 137
    • 84862727180 scopus 로고    scopus 로고
    • Rethinking inflammation: Neural circuits in the regulation of immunity
    • Olofsson PS, Rosas-Ballina M, Levine YA, Tracey KJ: Rethinking inflammation: Neural circuits in the regulation of immunity. Immunol Rev 248(1): 188-204, 2012
    • (2012) Immunol Rev , vol.248 , Issue.1 , pp. 188-204
    • Olofsson, P.S.1    Rosas-Ballina, M.2    Levine, Y.A.3    Tracey, K.J.4
  • 139
    • 0037348980 scopus 로고    scopus 로고
    • Tolllike receptor 4 expression levels determine the degree of LPS-susceptibility in mice
    • Kalis C, Kanzler B, Lembo A, Poltorak A, Galanos C, Freudenberg MA: Tolllike receptor 4 expression levels determine the degree of LPS-susceptibility in mice. Eur J Immunol 33(3):798-805, 2003
    • (2003) Eur J Immunol , vol.33 , Issue.3 , pp. 798-805
    • Kalis, C.1    Kanzler, B.2    Lembo, A.3    Poltorak, A.4    Galanos, C.5    Freudenberg, M.A.6
  • 141
    • 59649104517 scopus 로고    scopus 로고
    • Toll-like receptor pathway signaling is differently regulated in neutrophils and peripheral mononuclear cells of patients with sepsis, severe sepsis, and septic shock
    • Salomao R, Brunialti MK, Gomes NE, Mendes ME, Diaz RS, Komninakis S, Machado FR, Da Silva ID, Rigato O: Toll-like receptor pathway signaling is differently regulated in neutrophils and peripheral mononuclear cells of patients with sepsis, severe sepsis, and septic shock. Crit Care Med 37(1): 132-139, 2009
    • (2009) Crit Care Med , vol.37 , Issue.1 , pp. 132-139
    • Salomao, R.1    Brunialti, M.K.2    Gomes, N.E.3    Mendes, M.E.4    Diaz, R.S.5    Komninakis, S.6    Machado, F.R.7    Da Silva, I.D.8    Rigato, O.9
  • 142
    • 0030739250 scopus 로고    scopus 로고
    • Apoptosis in lymphoid and parenchymal cells during sepsis: Findings in normal and T- And B-cellYdeficient mice
    • Hotchkiss RS, Swanson PE, Cobb JP, Jacobson A, Buchman TG, Karl IE: Apoptosis in lymphoid and parenchymal cells during sepsis: Findings in normal and T- And B-cellYdeficient mice. Crit Care Med 25(8):1298-1307, 1997
    • (1997) Crit Care Med , vol.25 , Issue.8 , pp. 1298-1307
    • Hotchkiss, R.S.1    Swanson, P.E.2    Cobb, J.P.3    Jacobson, A.4    Buchman, T.G.5    Karl, I.E.6
  • 147
    • 26444578150 scopus 로고    scopus 로고
    • Effect of increased cardiac output on hepatic and intestinal microcirculatory blood flow, oxygenation, and metabolism in hyperdynamic murine septic shock
    • Albuszies G, Radermacher P, Vogt J, Wachter U, Weber S, Schoaff M, Georgieff M, Barth E: Effect of increased cardiac output on hepatic and intestinal microcirculatory blood flow, oxygenation, and metabolism in hyperdynamic murine septic shock. Crit Care Med 33(10):2332-2338, 2005
    • (2005) Crit Care Med , vol.33 , Issue.10 , pp. 2332-2338
    • Albuszies, G.1    Radermacher, P.2    Vogt, J.3    Wachter, U.4    Weber, S.5    Schoaff, M.6    Georgieff, M.7    Barth, E.8
  • 150
    • 31344453460 scopus 로고    scopus 로고
    • Role of inducible nitric oxide synthase in the reduced responsiveness of the myocardium to catecholamines in a hyperdynamic, murine model of septic shock
    • Barth E, Radermacher P, Thiemermann C, Weber S, Georgieff M, Albuszies G: Role of inducible nitric oxide synthase in the reduced responsiveness of the myocardium to catecholamines in a hyperdynamic, murine model of septic shock. Crit Care Med 34(2):307-313, 2006
    • (2006) Crit Care Med , vol.34 , Issue.2 , pp. 307-313
    • Barth, E.1    Radermacher, P.2    Thiemermann, C.3    Weber, S.4    Georgieff, M.5    Albuszies, G.6
  • 153
    • 0028288683 scopus 로고
    • Acute effects of nitric oxide on left ventricular relaxation and diastolic distensibility in humans assessment by bicoronary sodium nitroprusside infusion
    • Paulus WJ, Vantrimpont PJ, Shah AM: Acute effects of nitric oxide on left ventricular relaxation and diastolic distensibility in humans. Assessment by bicoronary sodium nitroprusside infusion. Circulation 89(5):2070, 1994
    • (1994) Circulation , vol.89 , Issue.5 , pp. 2070
    • Paulus, W.J.1    Vantrimpont, P.J.2    Shah, A.M.3
  • 155
    • 84879114381 scopus 로고    scopus 로고
    • Mechanism of interleukin-1 modulation of intestinal epithelial barrier involves p38 kinase and activating transcription factor-2 activation
    • Al-Sadi R, Guo S, Dokladny K, Alhmound T, Ereifej L, Said HM, Ma TY: Mechanism of interleukin-1 modulation of intestinal epithelial barrier involves p38 kinase and activating transcription factor-2 activation. J Immunol 190(12):6596-6606, 2013
    • (2013) J Immunol , vol.190 , Issue.12 , pp. 6596-6606
    • Al-Sadi, R.1    Guo, S.2    Dokladny, K.3    Alhmound, T.4    Ereifej, L.5    Said, H.M.6    Ma, T.Y.7
  • 156
    • 0025442212 scopus 로고
    • Role of interleukin 1 in inflammatory bowel diseaseYenhanced production during active disease
    • Ligumsky M, Simon PL, Karmeli F, Rachmilewitz D: Role of interleukin 1 in inflammatory bowel diseaseYenhanced production during active disease. Gut 31(6):686-689, 1990
    • (1990) Gut , vol.31 , Issue.6 , pp. 686-689
    • Ligumsky, M.1    Simon, P.L.2    Karmeli, F.3    Rachmilewitz, D.4
  • 157
    • 33947631511 scopus 로고    scopus 로고
    • IL-1beta causes an increase in intestinal epithelial tight junction permeability
    • Al-Sadi RM, Ma TY: IL-1beta causes an increase in intestinal epithelial tight junction permeability. J Immunol 178(7):4641-4649, 2007
    • (2007) J Immunol , vol.178 , Issue.7 , pp. 4641-4649
    • Al-Sadi, R.M.1    Ma, T.Y.2
  • 158
    • 45949086355 scopus 로고    scopus 로고
    • Mechanism of IL-1betaYinduced increase in intestinal epithelial tight junction permeability
    • Al-Sadi R, Ye D, Dokladny K, Ma TY: Mechanism of IL-1betaYinduced increase in intestinal epithelial tight junction permeability. J Immunol 180(8): 5653-5661, 2008
    • (2008) J Immunol , vol.180 , Issue.8 , pp. 5653-5661
    • Al-Sadi, R.1    Ye, D.2    Dokladny, K.3    Ma, T.Y.4
  • 159
    • 33749428028 scopus 로고    scopus 로고
    • Coordinated epithelial NHE3 inhibition and barrier dysfunction are required for TNFmediated diarrhea in vivo
    • Clayburgh DR, Musch MW, Leitges M, Fu YX, Turner JR: Coordinated epithelial NHE3 inhibition and barrier dysfunction are required for TNFmediated diarrhea in vivo. J Clin Invest 116(10):2682-2694, 2006
    • (2006) J Clin Invest , vol.116 , Issue.10 , pp. 2682-2694
    • Clayburgh, D.R.1    Musch, M.W.2    Leitges, M.3    Fu, Y.X.4    Turner, J.R.5
  • 162
    • 77149169405 scopus 로고    scopus 로고
    • Nod2 regulates the host response towards microflora by modulating T cell function and epithelial permeability in mouse Peyers patches
    • Barreau F, Madre C, Meinzer U, Berrebi D, Dussaillant M, Merlin F, Eckmann L, Karin M, Sterkers G, Bonacorsi S: Nod2 regulates the host response towards microflora by modulating T cell function and epithelial permeability in mouse Peyers patches. Gut 59(2):207-217, 2010
    • (2010) Gut , vol.59 , Issue.2 , pp. 207-217
    • Barreau, F.1    Madre, C.2    Meinzer, U.3    Berrebi, D.4    Dussaillant, M.5    Merlin, F.6    Eckmann, L.7    Karin, M.8    Sterkers, G.9    Bonacorsi, S.10
  • 165
    • 13844308129 scopus 로고    scopus 로고
    • Mechanism of TNF-{alpha} modulation of Caco-2 intestinal epithelial tight junction barrier: Role of myosin light-chain kinase protein expression
    • Ma TY, Boivin MA, Ye D, Pedram A, Said HM: Mechanism of TNF-{alpha} modulation of Caco-2 intestinal epithelial tight junction barrier: Role of myosin light-chain kinase protein expression. Am J Physiol Gastrointest Liver Physiol 288(3):G422YG430, 2005
    • (2005) Am J Physiol Gastrointest Liver Physiol , vol.288 , Issue.3
    • Ma, T.Y.1    Boivin, M.A.2    Ye, D.3    Pedram, A.4    Said, H.M.5
  • 167
    • 34250823515 scopus 로고    scopus 로고
    • Gene-specific control of inflammation by TLR-induced chromatin modifications
    • Foster SL, Hargreaves DC, Medzhitov R: Gene-specific control of inflammation by TLR-induced chromatin modifications. Nature 447(7147): 972-978, 2007
    • (2007) Nature , vol.447 , Issue.7147 , pp. 972-978
    • Foster, S.L.1    Hargreaves, D.C.2    Medzhitov, R.3
  • 168
    • 77952395705 scopus 로고    scopus 로고
    • Potent phagocytic activity with impaired antigen presentation identifying lipopolysaccharide-tolerant human monocytes: Demonstration in isolated monocytes from cystic fibrosis patients
    • Del Fresno C, García-Rio F, Gómez-Piña V, Soares-Schanoski A, Fernández- Ruíz I, Jurado T, Kajiji T, Shu C, Marín E, Gutierrez Del Arroyo A, et al.: Potent phagocytic activity with impaired antigen presentation identifying lipopolysaccharide-tolerant human monocytes: Demonstration in isolated monocytes from cystic fibrosis patients. J Immunol 182(10):6494-6507, 2009
    • (2009) J Immunol , vol.182 , Issue.10 , pp. 6494-6507
    • Del Fresno, C.1    García-Rio, F.2    Gómez-Piña, V.3    Soares-Schanoski, A.4    Fernández- Ruíz, I.5    Jurado, T.6    Kajiji, T.7    Shu, C.8    Marín, E.9    Gutierrez Del Arroyo, A.10
  • 169
    • 79251599459 scopus 로고    scopus 로고
    • Differential expression of Toll-like receptor signaling cascades in LPS-tolerant human peripheral blood mononuclear cells
    • MendesME, Baggio-Zappia GL, Brunialti MK, Fernandes Mda L, RapozoMM, Salomao R: Differential expression of Toll-like receptor signaling cascades in LPS-tolerant human peripheral blood mononuclear cells. Immunobiology 216(3):285-295, 2011
    • (2011) Immunobiology , vol.216 , Issue.3 , pp. 285-295
    • Mendes, M.E.1    Baggio-Zappia, G.L.2    Brunialti, M.K.3    Fernandes M Da, L.4    Rapozo, M.M.5    Salomao, R.6
  • 171
    • 84856401404 scopus 로고    scopus 로고
    • Protein metabolism and gene expression in skeletal muscle of critically ill patients with sepsis
    • Klaude M, Mori M, Tjäder I, Gustafsson T, Wernerman J, Rooyackers O: Protein metabolism and gene expression in skeletal muscle of critically ill patients with sepsis. Clin Sci (Lond) 122(3):133-142, 2012
    • (2012) Clin Sci (Lond) , vol.122 , Issue.3 , pp. 133-142
    • Klaude, M.1    Mori, M.2    Tjäder, I.3    Gustafsson, T.4    Wernerman, J.5    Rooyackers, O.6
  • 172
    • 77956679005 scopus 로고    scopus 로고
    • BCATm deficiency ameliorates endotoxininduced decrease in muscle protein synthesis and improves survival in septic mice
    • Lang CH, Lynch CJ, Vary TC: BCATm deficiency ameliorates endotoxininduced decrease in muscle protein synthesis and improves survival in septic mice. Am J Physiol Regul Integr Comp Physiol 299(3):R935YR944, 2010
    • (2010) Am J Physiol Regul Integr Comp Physiol , vol.299 , Issue.3
    • Lang, C.H.1    Lynch, C.J.2    Vary, T.C.3
  • 173
    • 0032470556 scopus 로고    scopus 로고
    • Sequential changes in the metabolic response in severely septic patients during the first 23 days after the onset of peritonitis
    • Plank LD, Connolly AB, Hill GL: Sequential changes in the metabolic response in severely septic patients during the first 23 days after the onset of peritonitis. Ann Surg 228(2):146-158, 1998
    • (1998) Ann Surg , vol.228 , Issue.2 , pp. 146-158
    • Plank, L.D.1    Connolly, A.B.2    Hill, G.L.3
  • 174
    • 1542374453 scopus 로고    scopus 로고
    • Inhibition of the tissue factor/factor VIIa pathway does not influence the inflammatory or antibacterial response to abdominal sepsis induced by Escherichia coli in mice
    • Weijer S, Schoenmakers SH, Florquin S, Levi M, Vlasuk GP, Rote WE, Reitsma PH, Spek CA, Van Der Poll T: Inhibition of the tissue factor/factor VIIa pathway does not influence the inflammatory or antibacterial response to abdominal sepsis induced by Escherichia coli in mice. J Infect Dis 189(12): 2308-2317, 2004
    • (2004) J Infect Dis , vol.189 , Issue.12 , pp. 2308-2317
    • Weijer, S.1    Schoenmakers, S.H.2    Florquin, S.3    Levi, M.4    Vlasuk, G.P.5    Rote, W.E.6    Reitsma, P.H.7    Spek, C.A.8    Van Der Poll, T.9
  • 178
    • 33747483345 scopus 로고    scopus 로고
    • Carbamoyl phosphate synthase-1: A marker of mitochondrial damage and depletion in the liver during sepsis
    • Crouser ED, Julian MW, Huff JE, Struck J, Cook CH: Carbamoyl phosphate synthase-1: A marker of mitochondrial damage and depletion in the liver during sepsis. Crit Care Med 34(9):2439-2446, 2006
    • (2006) Crit Care Med , vol.34 , Issue.9 , pp. 2439-2446
    • Crouser, E.D.1    Julian, M.W.2    Huff, J.E.3    Struck, J.4    Cook, C.H.5
  • 188
  • 193
    • 80053173045 scopus 로고    scopus 로고
    • Treatment with gelsolin reduces brain inflammation and apoptotic signaling in mice following thermal injury
    • Zhang QH, Chen Q, Kang JR, Liu C, Dong N, Zhu XM, Sheng ZY, Yao YM: Treatment with gelsolin reduces brain inflammation and apoptotic signaling in mice following thermal injury. J Neuroinflammation 8:118, 2011
    • J Neuroinflammation , vol.8 , Issue.118 , pp. 2011
    • Zhang, Q.H.1    Chen, Q.2    Kang, J.R.3    Liu, C.4    Dong, N.5    Zhu, X.M.6    Sheng, Z.Y.7    Yao, Y.M.8
  • 195
    • 33644657307 scopus 로고    scopus 로고
    • Relationship of plasma gelsolin levels to outcomes in critically ill surgical patients
    • Lee PS, Drager LR, Stossel TP, Moore FD, Rogers SO: Relationship of plasma gelsolin levels to outcomes in critically ill surgical patients. Ann Surg 243(3):399-403, 2006
    • (2006) Ann Surg , vol.243 , Issue.3 , pp. 399-403
    • Lee, P.S.1    Drager, L.R.2    Stossel, T.P.3    Moore, F.D.4    Rogers, S.O.5
  • 196
    • 80055105130 scopus 로고    scopus 로고
    • Reduction of plasma gelsolin levels correlates with development of multiple organ dysfunction syndrome and fatal outcome in burn patients
    • Huang LF, Yao YM, Li JF, Dong N, Liu C, Yu Y, He LX, Sheng ZY: Reduction of plasma gelsolin levels correlates with development of multiple organ dysfunction syndrome and fatal outcome in burn patients. PLoS One 6(11):e25748, 2011
    • (2011) PLoS One , vol.6 , Issue.11
    • Huang, L.F.1    Yao, Y.M.2    Li, J.F.3    Dong, N.4    Liu, C.5    Yu, Y.6    He, L.X.7    Sheng, Z.Y.8


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